1.Clinical experience with IABP: report of 12 cases.
Weon Yong LEE ; Jun Young CHOI ; Kyung Phill SUH
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(3):287-291
No abstract available.
2.A Case of Callus Induced By Tophi.
Young Sik RYU ; Jong Gap PARK ; Jun Young LEE ; Jin Wou KIM ; Eun Joo SUH
Korean Journal of Dermatology 1997;35(2):365-368
Callus is a nonpenetrating circumscribed hyperkeratosis produced by repeated friction or pressure. It occurs on parts subjected to intermittent pressure, particularly on the palms and soles, and particularly over the bony prominences of the joints. In painful callosities of the feet, ill-fitting shoes and orthopedic problems of the foot (bunions, exostoses) are some of the etiological factors to be considered. Gout is a condition of inborn metabolic and/or acquired form of the disease characterized by hyperuricemia, tophaceous deposits of sodium urate and recurrent attacks of arthritis. We present a case of callus caused by tophi. The patient was a 45-year-old man who had complained of a painful, well-demarcated, hyperkeratotic plaque on the heel of the left foot for 18 months. After the tophi beneath overlying whitish thickened skin had been removed, the skin lesion disappeared and to date has not recurred.
Arthritis
;
Bony Callus*
;
Callosities
;
Foot
;
Friction
;
Gout
;
Heel
;
Humans
;
Hyperuricemia
;
Joints
;
Middle Aged
;
Orthopedics
;
Shoes
;
Skin
;
Uric Acid
3.The mRNA Expression of Phosphoinositide-specific Phospholipase C-beta Isozymes in Postnatal Rat Brains.
Im Joo RHYU ; Hyun KIM ; Yoon Hee KANG ; Kyoungsook PARK ; Seung Jun HWANG ; Pann Ghill SUH ; Young Suk SUH
Korean Journal of Anatomy 1998;31(4):535-544
Phosphoinositide-specific phospholipase C(PLC) is known as a key enzyme which produces two major second messengers: diacylglycerol and inositol 1,4,5 trisphosphate. Although it has been suggested that PLC beta isozymes have important roles in nervous system, less is known about the function of PLC beta in development of nervous system. We have localized the mRNA expressions of PLC beta isozymes in the postnatal rat brains by id firm hybridization histochemistry. In the postnatal rat brains, each isozyme of PLC beta showed differential expression pattern. The expression of PLC beta1 mRNA was found in various areas including olfactory bulb, cerebral cortex, caudate putamen, hippocampus, dentate gyrus, and cerebellum. In general, the expression in these areas was gradually increased after birth (PO) until postnatal day 21 (P2l) and slightly decreased to adult level. The expression of PLC beta2 mRNA was not found in postnatal rat brains. The expression of PLC beta3 mRNA was found from P0, peaked at Pl4, and decreased to adult level in the purkinje cells of cerebellum. PLC beta4 mRNA was strongly expressed in the thalamus, cerebellum, cerebral cortex, and olfactory bulb. In these areas, the expression was gradually increased after birth, peaked at P2l, and decreased to adult level. In whole body parasagittal sections of 18 day old rat embryo, PLC betal mRNA was exclusively expressed in nervous tissue, PLC beta3 and PLC beta4 were expressed in various tissues, and the expression of PLC beta2 was not found in any kind of rat tissues. From the different spatiotemporal mRNA expression patterns of PLC beta isozymes in the postnatal rat brains, it is suspected that each PLC beta isozyme may have specific role in signal transduction for postnatal development of rat brain.
Adult
;
Animals
;
Brain*
;
Cerebellum
;
Cerebral Cortex
;
Dentate Gyrus
;
Embryonic Structures
;
Hippocampus
;
Humans
;
Inositol
;
Isoenzymes*
;
Nervous System
;
Olfactory Bulb
;
Parturition
;
Phospholipase C beta*
;
Phospholipases*
;
Purkinje Cells
;
Putamen
;
Rats*
;
RNA, Messenger*
;
Second Messenger Systems
;
Signal Transduction
;
Thalamus
4.A Case of Spontaneous Remission of Histiocytosis X.
Gun Su PARK ; Jun Young LEE ; Chung Won KIM ; Eun Joo SUH
Korean Journal of Dermatology 1995;33(2):379-383
Histiocytosis X(Langerhans cell histiocytosis) is a rare prolifertive disorder of Langerhans cells that includes Lettere-Siwe disease, Hand-Shiiller-Christian his ase and eosinophilic granuloma. Since many authors have reported in anintermediate and poarl classified form histiocytosis X has a namenclatural had nosologic problem. We report a case benign cutaneous variant of histiocytisis X. A four-month-old boy had shown multiple skin-colour papules on the trunk, head and nik for one month. Extensive in- vestigations failed to detcct any systemic involvement. The clixron microscopic findings of the skin biopsy specimen were Qefinitely diagnostic for histiocytosi. X Since he did not sbow evidence of internal organ involvernent and any further progression of he skin lesion, no therapy was given. Over the next two months the disease underwent spontane us and complete remission.
Biopsy
;
Eosinophilic Granuloma
;
Head
;
Histiocytosis*
;
Histiocytosis, Langerhans-Cell*
;
Humans
;
Langerhans Cells
;
Male
;
Remission, Spontaneous*
;
Skin
5.Relationship Between Initial Biochemical Bone Markers and Change of Bone Mineral Density of Postmenopausal Women with Short-term Hormone Replacement Therapy.
Sung Young PARK ; Yoo Suk SUH ; Sung Jun YOON ; Hyoung Moo PARK ; Min HUR
Korean Journal of Obstetrics and Gynecology 1999;42(9):1972-1979
OBJECTIVE: This study is proposed to examine the relationship between bone loss after hormone replacement therapy for one year and initial bone markers. METHODS: One hundred postmenopausal women were studied for one year. At first visit, measurements were made of bone mineral density(BMD) at the lumbar spine and femoral neck, and of serum osteocalcin and urine deoxypyridinoline. After hormone replacement therapy was done for one year, BMD was rechecked. RESULTS: Serum osteocalcin was correlated with the rate of bone change(r=0.150, 0.262) and urine deoxypyridinoline was weakly correlated(r=-0.003, 0.038). The changes of femoral BMD in women with higher concentration of osteocalcin and deoxypyridinoline were significant different from those in women with normal concentration. At the lumbar spine, no significant differences were showed. In women with higher concentration of osteocalcin, the incidence of subjects with increased spine BMD was increased up to around 71.1%, which showed not significant increase compared with normal concentration of osteocalcin. And the incidence of increased spine BMD in women with higher concentration of osteocalcin was marked increased compared with the incidence of normal concentration. The level of the osteocalcin with increased spine BMD was 11.5+/-6.6 ng/ml, and the level with decreased spine BMD was 9.2+/-4.7 ng/ml, respectively. And the level of the deoxypyridinoline was 7.2+/-4.2 pmol/ mol cr in women with increased spine BMD and 7.2+/-2.7 pmol/ mol cr in women with decreased spine BMD, which was not statistically different. The concentration of deoxypyridinoline with increased and decreased in BMD in spine and femur was not statistically different. but the concentration of osteocalcin was 12.2 +/-5.5 ng/ml in significantly increased in BMD and 8.5 +/-4.5ng/ml in significantly decreased in BMD, which was showed significant different. CONCLUSION: Present study indicates that the serum osteocalcin more reflcets bone turnover changes at the menopause than deoxypyridinoline, however, the clinical utility of measurements of osteocalcin only to response to therapy is uncertain.
Bone Density*
;
Female
;
Femur
;
Femur Neck
;
Hormone Replacement Therapy*
;
Humans
;
Incidence
;
Menopause
;
Osteocalcin
;
Spine
6.Atypical Eruption Due to Chemotherapeutic Agent.
Jun HUR ; Jae Young SEONG ; Tae Sik CHOI ; Kee Suck SUH ; Sang Tae KIM
Annals of Dermatology 2001;13(4):232-234
We report a case of atypical eruption due to chemotherapeutic agent in a 60-year-old man who presented with asymptomatic, erythematous, 0.5cm in diameter, confluent, and elevated papules and plaques confined to the face. The patient was previously diagnosed with small cell carcinoma of the lung with liver metastasis. Two months after the diagnosis, a first course of chemotherapy including etoposide was started. Five days after starting the chemotherapy, the patient developed a facial eruption. Histopathologic examination demonstrated increased epidermal mitotic figures, cells in metaphase arrest, basal cell layer hyperpigmentation, prominent dyskeratosis, and squamous atypia. The most distinctive histologic feature was the presence of starburst cells, which are markedly enlarged pale staining keratinocytes containing small basophilic fragments of nuclear debris haphazardly scattered throughout the cytoplasm in a starburst pattern.
Basophils
;
Carcinoma, Small Cell
;
Cytoplasm
;
Diagnosis
;
Drug Therapy
;
Etoposide
;
Humans
;
Hyperpigmentation
;
Keratinocytes
;
Liver
;
Lung
;
Metaphase
;
Middle Aged
;
Neoplasm Metastasis
7.A Case of Spindle Cell Hemangioendothelioma.
Jun Gyu JANG ; Hyun Chul KIM ; Young Soo CHAE ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1997;35(2):322-326
Spindle cell hemangioendothelioma was first described in 1986 by Weiss and Enzinger as a low grade angiosarcoma resr mbling a cavernous hemangioma and kaposis sarcoma. Recently, it is suggested to be non neoplastic lesion or reactive process arising from pre-existing vascular mal- formation. We report a case of spindle cell hemangioendothelioma in a 9-month-old boy. He had multiple, variable sized, colorful, cutaneous or subcutaneous nodules on the forearm and hand. The tumor first appeared on the forearm as erythematous patches at birth and grew rapidly with- in 3 months. Histopatholgical findings showed that the lesion was composed of thin walled cavernous spaces mixed with spindle cells and occasional epithelioid endothelial cells containing intracytoplasmic vacuole. Most af the endothelial cells lining the cavernous spaces and intracytoplasmic lumina, were positive for factor VIII associated antigen. But the spindle cells were negative. Atypical vascular structures resembling arteriovenous shunts were noted around the tumor suggesting a reactive proliferation due to disturbance of local blood flow. Several turnors were excised. No recurrence has been recognized in the one year- follow-up period.
Endothelial Cells
;
Factor VIII
;
Follow-Up Studies
;
Forearm
;
Hand
;
Hemangioendothelioma*
;
Hemangioma, Cavernous
;
Hemangiosarcoma
;
Humans
;
Infant
;
Male
;
Parturition
;
Recurrence
;
Sarcoma, Kaposi
;
Vacuoles
8.Transurethral Dormia Dislodging in Patients with Lower Ureteral Stone.
Eun Gill KIM ; Jun Kyu SUH ; Young Soo KIM ; Tong Choon PARK
Yeungnam University Journal of Medicine 1985;2(1):81-85
Management of the small lower ureteral stone has been attempted by either transurethral manipulation or expectant therapy. To date, however, the choice of proper method has depended mostly on clinician's preference, and the effectiveness of the transurethral stone manipulation has remained controversial. Herein we evaluated the effectiveness of the transurethral stone manipulation, using with the Dormia dislodger, in 37 patients with lower ureteral stone less than 10mm in greatest diameter. The results are summarized as follows. 1. The overall success rate was 68% (25 of 37 patients); Immediate delivery of the stone was observed in 16 of 37 patients. In another 5 patients the stone was removed at the time when the indwelled ureteral catheter was taken out. In the remaining 4 patients the stone passed spontaneously within a week following the procedure. 2. Higher success rate was observed in smaller stone; 79% in less than 4 mm, 58% in 46 mm, and 33% in 610 mm in it's greatest diameter, respectively. 3. The morbidity rate was 8.1% (3 of 37 patients); In one patient a broken basket was retained in the ureter, which was removed at the time of ureterolithotomy. In another patient a ureteral stricture requiring periodic dilation was complicated. And in the other patient persistent hematuria was observed, which was relieved by conservative management. These results suggest that transurethral manipulation might have to be initially applied to unremittingly painful patients with small lower ureteral stone.
Constriction, Pathologic
;
Hematuria
;
Humans
;
Methods
;
Ureter*
;
Urinary Catheters
9.A Case of Retrocaval Ureter with Left Renal Agenesis.
Seong Tae KIM ; Jun Kyu SUH ; Young Soo KIM ; Tong Choon PARK
Korean Journal of Urology 1987;28(1):143-146
Retrocaval ureter is a rare congenital anomaly of the urogenital organ originating from the venous maldevelopment. To our knowledge, retrocaval ureter with contralateral renal agenesis has not been reported in Korea. Recently, we experienced a case of retrocaval ureter with contralateral renal agenesis, and obtained a good result following ureteral resection with end-to-end anastomosis of the ureter.
Korea
;
Retrocaval Ureter*
;
Ureter
10.A Case of Squamous Cell Carcinoma with Colonic Polyp in Female Urethra.
Ju Seuk KIM ; Do Hwan SEONG ; Jun Kyu SUH ; Kwang Hoon LEE ; Jee Young HAN
Korean Journal of Urology 2000;41(10):1281-1284
No abstract available.
Carcinoma, Squamous Cell*
;
Colon*
;
Colonic Polyps*
;
Female*
;
Humans
;
Urethra*