1.Effect of Long-Term Benzodiazepines for Chronic Insomnia on Cognitive Function and Waking Electroencephalography: A Case-Control Study
Young Rong BANG ; Hong Jun JEON ; In-Young YOON
Psychiatry Investigation 2022;19(4):259-267
Objective:
The relationship between benzodiazepine use and cognitive decline in insomnia patients has been reported, but still conflicting. Thus, we tried to determine whether long-term exposure of benzodiazepine might be associated with changes of cognition and electroencephalography (EEG) findings in patients with chronic insomnia.
Methods:
Insomniacs using benzodiazepines (n=29), drug-free insomniacs (n=27), and age- and sex-matched controls (n=28) were recruited. Neurocognitive function tested with Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet Neuropsychological Assessment Battery, quantitative EEG in awake state, and information of benzodiazepine usage were obtained.
Results:
Drug-free insomniacs reported more severe symptoms than insomniacs using benzodiazepine (p<0.001). Insomniacs using benzodiazepine showed a decrease of executive function in Trail Making Test A than drug-free insomniacs and controls (0.73±0.66 vs. 1.27±0.38 vs. 1.09±0.47, p<0.001) and in categorical fluency than drug-free insomniacs (-0.01±0.99 vs. 1.26±0.97, p=0.002). However, such decrease of executive function was not proportional to daily dose or cumulative dose of benzodiazepine. The EEG was not significantly different between insomniacs using benzodiazepine and drug-free insomniacs, while EEG of insomniacs showed low relative theta power in frontal and parietal regions but high relative beta power in frontal region than that of controls.
Conclusion
Benzodiazepine users with chronic insomnia showed an impairment of executive function compared to drug-free insomniacs and controls although they showed relatively decreased severity of insomnia symptoms. Chronic insomniacs showed a hyper-arousal manifestation in front-parietal region of brain regardless of benzodiazepine exposure.
2.A Case of Block Dot Ringworm Caused by trichophyton tonsurans.
Soon Bong SUH ; Sung Wha KIM ; Soo Hee OH ; Sung Koan CHOI ; Young Jun BANG
Korean Journal of Dermatology 1998;36(5):918-923
Trichophyton tonsurans is a major causative agent of tinea capitis in the United States, Canada, Mezico and other Latin American countries, but the infection of T.tonsurans has not been reported in Korea. We report a case of tinea capitis caused by T. tonsurans in a 15-year-old student wrestler. He had a 3*3cm sized non-inflammatory alopecia with black dots on the right occipital area of the scalp. The diagnosis was established by a hght microscopic examination of the affected hairs and by mycological studies from cultures. To our knowledge, this is the first case in which T. tonsurans has been isolated in Korea, It is likely that the student acquired the infection through contact with a foreign wrestler during interaational games and practice. We should be concerned about the potential of spread of this infection in our country.
Adolescent
;
Alopecia
;
Canada
;
Diagnosis
;
Hair
;
Humans
;
Korea
;
Scalp
;
Tinea Capitis
;
Tinea*
;
Trichophyton*
;
United States
3.Clinicopathological Analysis of Malignant Germ Cell Tumors of Ovary.
Jun Bae BANG ; II Soo PARK ; Jae Chul SIM ; Young Chul CHOI
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):388-396
Malignant germ cell tumors occur in children and young women in reproductive age, of all the germ cell malignancies, only pure dysgerminomas had a high cure rate prior to 1970. This was due to the exquisite radiosensitivity of these tumors. Multiple-agent chemotherapy has dramatically improved the pmgnosis of patients with malignant ovarian germ cell tumors. Clinicopathological analysis was performed on 21 cases of malignant germ cell tumors of the ovary, 9 cases at the department of Obstetrics & Gynecology, Kyung-pook National University Hospital, 4 cases, at the department of Obstetrics and Gynecology, Dong-guk University Kyungju Hospital and 8 cases, at the department of Obstetrics and Gynecology, Dae-gu Fatima Hospital during the period 10 years from July. 19S8 to June. 1997 The results were summarized as follows: 1. The mean age of the patients was 21.8 years old, ranging from 10 to 61 years old. 2. Main initial symptoms were abdominal distension(33.3%), abdominal mass palpation(33.3%), abdominal pain(28.6%), amenorrhea(4.8%) in order. 3. Histologically, the tumors were classified as immature teratoma(57.1%), dysgerminoma(19%), mixed germ cell tumor(9.5%), endodermal sinus tumor(9.5%), embryonal cell carcinoma(4.8%). 4, According to FIGO classification Stage I was the most prevalent(57.1%) at the time of diagnosis while Stage III was forward in 48.6%, Stage II in 9.5%, and no Stage IV, 5. The 5-year survival rate was 80.4% and three patients have died of malignancy and the other 18 patients live without disease from 11 to 102 months, with a median follow-up of 34.2 months. 6. Prognostic factors of malignant germ cell tumors in this study were the clinical stage, the presence of ascites and the residual tumor mass.
Ascites
;
Child
;
Classification
;
Daegu
;
Diagnosis
;
Drug Therapy
;
Dysgerminoma
;
Endoderm
;
Female
;
Follow-Up Studies
;
Germ Cells*
;
Gyeongsangbuk-do
;
Gynecology
;
Humans
;
Middle Aged
;
Neoplasm, Residual
;
Neoplasms, Germ Cell and Embryonal*
;
Obstetrics
;
Ovary*
;
Radiation Tolerance
;
Survival Rate
4.A Case of Priapism.
Woo Young JANG ; Bang Whan JUN ; Hae Young PARK ; Hyun Jae NA
Korean Journal of Urology 1986;27(6):971-975
Priapism is an uncommon condition of prolonged painful penile erection, and no sexual excitement or desire is present. The therapeutic goal in priapism is to restore normal circulation and blood flow in the erectile tissue of corporacavernosa. In recent years medical treatment is unsuccessful and it should be treated as a surgical emergency. Here we report one case of priapism with review of related recent references.
Emergencies
;
Male
;
Penile Erection
;
Priapism*
5.A case of carcinomatous polyarthritis.
Suk In LEE ; Woo Kyung KIM ; Jae Suk JUN ; Kyung Ran BAIK ; Sung Hyun YANG ; Young Joo BANG ; Young Ok SONG
Journal of the Korean Cancer Association 1993;25(2):307-314
No abstract available.
Arthritis*
6.A Case of Multiple Trichoepitheliomas and Basal Cell Carcinomas Co-existed on the Nose
Hyo Jung KIM ; Ju Hee HAN ; Chul Hwan BANG ; Jun Young LEE ; Ji Hyun LEE ; Young Min PARK
Korean Journal of Dermatology 2019;57(3):164-166
No abstract available.
Carcinoma, Basal Cell
;
Nose
7.Comparison between Second and Third Generation Piezoelectric Lithotripsy in Children & Adolescents.
Seung Hyeun AHN ; Jang Ho BANG ; Won Jun KAI ; Young Tae MOON
Korean Journal of Urology 1997;38(6):600-604
During a 9-year period 43 children and adolescents 2 to 18 years old underwent 140 extracorporeal shock wave lithotripsy (ESWL) treatments for 48 calculi. The second generation piezoelectric lithotriptor (LT01) was used in 28 cases (65%) while the remaining cases were treated with the third generation piezoelectric lithotriptor (LT02). LT02 lithotriptor differs from an earlier model LT01 in 2 important respects; a stone localization system consisting of ultrasound and fluoroscopy, and more energy per shock wave. The LT01 necessitated caudal anesthesia in 14 cases (50%) while the LT02 necessitated caudal anesthesia in 2 cases (13%) and intravenous anesthesia in 2 cases (13%). Two upper ureteral stones without ureteral dilatation and 1 mid ureteral stone, which were difficult to detect with ultrasound, could be localized by combined ultrasound and fluoroscopy on LT02. The success rate by LT01 and LT02 ESWL was 92.9% and 100%, respectively. The mean session of LT01 and LT02 ESWL was 3.6+/-.4.09 and 2.6+/-2.47, respectively, and the total storage of LT02 ESWL (93+/-97.8) was much less(p<0.05) than that of LT01 ESWL (363+/-380.3). There were no statistical differences in regard to success and the use of stents, stone size or location between the 2 lithotriptors. Six patients required adjuvant procedures, and ESWL complications were not required admission or surgical management. Therefore, LT02 piezoelectric lithotripsy, in comparison with LT01, is more efficient to localize stones and can lessen total storage by reducing treatment sessions in children and adolescents.
Adolescent*
;
Anesthesia, Caudal
;
Anesthesia, Intravenous
;
Calculi
;
Child*
;
Dilatation
;
Fluoroscopy
;
Humans
;
Lithotripsy*
;
Shock
;
Stents
;
Ultrasonography
;
Ureter
;
Urinary Calculi
8.Prevalence of Tinea Pedis of College Students and Their Families in Taegu.
Hae Ook CHO ; Dong Hoon SHIN ; Jong Soo CHOI ; Ki Hong KIM ; Young Jun BANG ; Soon Bong SUH
Korean Journal of Dermatology 1997;35(1):114-120
BACKGROUND: Tinea pedis is one of the most comrnon dermatoses in the general population. But its prevalence in the general populat,ion was not yet reported in Korea. OBJECTIVE: Prevalence of tinea pedis and associated tinea unguium were checked in the general population. METHODS: Six hundred fifty eight persons from 179 families of the college students were evaluated. Clinical examinatior. for tinea pedis and onychomycosis and collecting scales from the suspicious lesions of the family members were perforrned by educated college students. Then dermatologists exarnined those specimens mycologically by KOH ~tnount and fungal culture. RESULTS: The results were as follows 1. The prevalence of tinea pedis was 41.2% in the studied 658 persons. 2. Among all 271 patients with tinea pedis, 201 strains of dermatophytes were isolated. They were 143 strains of Trichophyton(T) rubrum, 49 strains of T. mentagrophytes and 9 mixed infections of T. rubrum and T. mentagrophytes. In the co existence of i,inea pedis and tinea unguiurn, isolated species were corresponding. 3. Among 179 families, 143 families (79.9%) had at least one patient with tinea pedis. The isolated species of derrnatophytes in a farnily were one organism, 71.4% and two or more organisms, 28.6% of 77 familiys with more than one patient. CONCLUSION: In our study, the prevalence rate of tinea pedis was 41.2%. That suggests that tinea pedis is a wide spr .ad disease in healthy adult in Korea.
Adult
;
Arthrodermataceae
;
Coinfection
;
Daegu*
;
Humans
;
Korea
;
Onychomycosis
;
Prevalence*
;
Skin Diseases
;
Tinea Pedis*
;
Tinea*
;
Weights and Measures
9.In Memory of Professor Soon Bong Suh
Weon Ju LEE ; Min Ji KIM ; Young Jun BANG
Korean Journal of Medical Mycology 2018;23(3):84-90
10.Comparison of characteristics between fatty and normal liver diagnosed by abdominal ultrasonography.
Heung Won JUN ; Eung Soo KIM ; Young Ryong PARK ; Mi Kyung OH ; Hye Ree LEE ; Bang Bu YOUN
Journal of the Korean Academy of Family Medicine 1991;12(12):1-6
No abstract available.
Liver*
;
Ultrasonography*