1.Clinical Response of Combined Androgen Blockade in Metastatic Prostate Cancers.
Suk Young LEE ; Young Sig KIM ; Sung Joon HONG
Korean Journal of Urology 2000;41(3):361-366
No abstract available.
Prostate*
;
Prostatic Neoplasms*
2.The Expression of L-type Calcium Channel mRNA by the Concentrations of Glucose on the Cell Proliferation in Cultured OLETF Rat Aortic Vascular Smooth Muscle Cells.
Hyung Joon YOO ; Young Jung CHO ; Hong Woo NAM
Journal of the Korean Geriatrics Society 2004;8(4):191-195
BACKGROUND: The proliferation of vascular smooth muscle cell(VSMC) is a part of the major pathogenic mechanism for atheroscle- rosis. It has been reported that L-type calcium channel plays a role in the VSMC proliferation in diabetic rats. But there is a little study results about the association between L-type calcium channel and VSMC proliferation by glucose concentrations in culture media. So we examined the association between voltage-dependent L-type calcium channel of VSMCs and the proliferative activity of vascular smooth muscle cells. METHODS: Rat aortic VSMCs were isolated from the aorta of OLETF rat by enzyme method. VSMCs were cultured in various concentrations of glucose(5.5, 25 mM). The VSMCs(1x104 cells in 24-well plates) were incubated in the presence of Bay K 8644 (10-6M) with/without verapamil(10-6M) for 48 hours. Then the proliferation was assessed by MTT(methylthiazole tetrazolium) assay and expression of L-type calcium channel mRNA was measured by RT-PCR. RESULTS: The proliferative ability and the expression of L-type calcium channel of cultured VSMCs were increased dose-dependently by the glucose concentrations(p<0.05). Bay K 8644 enhanced the proliferation of VSMC and verapamil blocked the incremental effects induced by Bay K 8644. CONCLUSION: These results suggest that L-type calcium channel may play a role in VSMC proliferation of OLETF rat.
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
;
Animals
;
Aorta
;
Calcium Channels, L-Type*
;
Cell Proliferation*
;
Culture Media
;
Glucose*
;
Muscle, Smooth, Vascular*
;
Rats
;
Rats, Inbred OLETF*
;
RNA, Messenger*
;
Verapamil
3.Determination of High Density Lipoprotein Cholesterol in Psoriasis Patients.
Joon Young SONG ; Kyu Suk LEE ; Jin Pyo HONG
Korean Journal of Dermatology 1986;24(4):493-498
In orper to measure the levels of high density lipoprotein cholesterol in psoriasis, 60 psoriatic patients and 30 healthy subjects were included in this study. Lopez-Virells methos was applied for measuring the serum level of high density lipoprotein cholesterol. The results were obtained as follows. The level of serurn HDL cholesterol was 58. 39+17. 40 mg/dl in psoratcs and 50.3+0.31 mg/dl in healthy subjects and 50. 43+ 10. 31 mg/dl in healthy subjects. No significant differences were noted between psoriatics & healthy subjects. 2. The level of serum HDL cholesterol was 56. 40+19. 10 mg/dl in male group of psoriatics and 60. 00+15.47 mg/dl in female group of psoriatics and 48.3+9. 50 mg/dl in healthy male group and 52.60 -10.59 mg/dl in healthy female group. No significant differences of serum HDL cholesteol levels were noted in both sexes.3. The mean value of serum HDL cholesterol by age groups of 10, 20, 30, 40, and 50 years old with psoriasis were 50. 70 mg/dl, 61. 97 mg/dl, 57. 44 mg/dl, 49. 11 mg/dl and 70. 36 mg/dl, respectively and those of healthy groups were 57. 25 mg/ dl, 45. 17 rng/dl, 50. 97 rng/dl, 48. 07 mg/dl and 46. 98 mg/dl, respectively.
Cholesterol, HDL*
;
Female
;
Humans
;
Male
;
Middle Aged
;
Psoriasis*
4.Postprostatectomy Urinary Incontinence, Impotence and Quality of Life Measurements.
Heon Gwan LIM ; Young Sig KIM ; Sung Joon HONG
Korean Journal of Urology 2000;41(1):118-123
No abstract available.
Erectile Dysfunction*
;
Male
;
Quality of Life*
;
Urinary Incontinence*
5.Postprostatectomy Urinary Incontinence, Impotence and Quality of Life Measurements.
Heon Gwan LIM ; Young Sig KIM ; Sung Joon HONG
Korean Journal of Urology 2000;41(1):118-123
No abstract available.
Erectile Dysfunction*
;
Male
;
Quality of Life*
;
Urinary Incontinence*
7.Diagnostic Approach to Angina Pectoris
Korean Journal of Medicine 2021;96(3):218-224
Stable angina is a chronic, systemic disease with a wide range of associated symptoms and clinical outcomes. Prompt diagnosis can be challenging for clinicians. Typical chest pain caused by stable angina occurs when the myocardium receives inadequate oxygen, resulting in myocardial ischemia. Various diagnostic tools including non-invasive tests such as coronary computed tomographic angiography and image-based stress tests have evolved over the last decade. An important factor in the selection of the proper diagnostic test for stable angina is assessment of the pre-test probability in the event of possible coronary arterial stenosis.
8.Diagnostic Approach to Angina Pectoris
Korean Journal of Medicine 2021;96(3):218-224
Stable angina is a chronic, systemic disease with a wide range of associated symptoms and clinical outcomes. Prompt diagnosis can be challenging for clinicians. Typical chest pain caused by stable angina occurs when the myocardium receives inadequate oxygen, resulting in myocardial ischemia. Various diagnostic tools including non-invasive tests such as coronary computed tomographic angiography and image-based stress tests have evolved over the last decade. An important factor in the selection of the proper diagnostic test for stable angina is assessment of the pre-test probability in the event of possible coronary arterial stenosis.
9.A Case of Malignamt Priapism due to Metastatic Prostate Cancer.
Sang Kwon BYON ; Chang Hee HONG ; Young Sig KIM ; Sung Eun KIM ; Sung Joon HONG
Korean Journal of Urology 2000;41(1):200-203
No abstract available.
Priapism*
;
Prostate*
;
Prostatic Neoplasms*
10.A Case of Malignamt Priapism due to Metastatic Prostate Cancer.
Sang Kwon BYON ; Chang Hee HONG ; Young Sig KIM ; Sung Eun KIM ; Sung Joon HONG
Korean Journal of Urology 2000;41(1):200-203
No abstract available.
Priapism*
;
Prostate*
;
Prostatic Neoplasms*