To know the efficacy of intravenous gammaglobulin(IVGG) treatment and the resulting outcome at 18 months for acute Guillain-Barr syndrome (GBS) in children, clinical courses of 27 GBS patients who had been treated with IVGG in a dose of 1g/kg/day oyer 2 consecutive days were investigated. One died with respiratory failure and 8 patients received assisted ventilatory care with improvement. All consecutively treated patients responded well to IVGG. The mean plateau period in 26 recovered patients was 8.5 days. At the 6th month evaluation, only one failed to reach grade 2 on GBSSG scales. At the 18th month evaluation, minor motor symptoms such as easy fatigability or mild tremor on writing were remained in 9 patients. 9 patients showed mild to moderate febrile response to IVGG infusion, but no significant side effects were noted. IVGG can be chosen as an initial treatment for acute GBS in children because of its rapid effect, relative safety even in unstable patients and convenience of administration.
Child* ; Humans ; Respiratory Insufficiency ; Tremor ; Weights and Measures ; Writing

Duplication of the urethra within a single penile shaft is a rare anomaly. These can be divided into those that are in the sagittal plane, which is most common, and those that occur side by side. In some cases, the accessory channel is complete, having a separate bladder opening and no communication with the more normal ventral urethra. In other cases, the accessory urethra is incomplete, either ending blindly or communicating with the urethra distal to the bladder neck. We report on a 20-year-old male with incomplete double urethra.
Humans ; Male ; Neck ; Urethra* ; Urinary Bladder ; Young Adult

PURPOSE: Cerebral cortical dysplasias are one of the important causes for epileptic seizures and developmental disabilities in children, particularly in diffuse or bilateral cases. These developmental malformations are generally regarded as a group of neuronal migration disorders, however, the classification system and pathogenetic mechanisms of cortical dysplasias are not yet entirely clear. Even a novel entity, congenital bilateral perisylvian syndrome, characterized by speech delay, pseudobulbar Palsy, intractable seizures, and bilateral perisylvian abnormalities on imaging studies, have rather diverse figures on morphology and symptomatology than initially considered. We have studied the clinical features and correlations of clinical outcomes 3nd magnetic resonance imaging(MRI) findings of bilaterally involved cortical dysplasias. METHODS: 20 cases of bilateral cortical dyspalsias were grouped into three categories on the basis of MRI findings; centroparietal dysplasias(6 cases), diffuse dysplasias with (5) or without white matter lesions(4), and schizencephaly(5). EEGs, motor and language development, epilepsy, and outcomes were reviewed in each groups. RESULTS: Language delay(100%), motor developmental delay(94.7%), motor deficit(65%), epilepsy(40%) were the main reasons for their initial hospital visits. A meaningful word expression was possible at the mean age of 2 years and 2 months(1 to 4 years of age). Hypotonia and spastic motor paralysis were evident in all the cases of diffuse dysplasia with white matter lesions and the schizencephaly groups. All but one case of centroparietal dysplasia showed motor developmental delay. Epilepsies were developed in 8 cases at the mean age of 5 years and 5 months(2 months to 12 years of age) and the seizures were relatively well controlled with anticonvulsants. EEG findings were variable; normal, focal or diffuse abnormalities. High amplitude diffuse fast activities were only noted in the diffuse dysplasia group. CONCLUSION: The severity of neurological deficits and developmental delay had correlated to the size of cortical abnormalities. The epilepsies were relatively well controlled during childhood and the EEG finding of high amplitude diffuse fast activities was specific for the diffuse cortical dysplasias. Bilateral centroparietal dysplasias should be included on consideration of the causes for developmental aphasia.
Anticonvulsants ; Aphasia ; Child ; Classification ; Developmental Disabilities ; Electroencephalography ; Epilepsy ; Humans ; Language Development ; Language Development Disorders ; Magnetic Resonance Imaging* ; Malformations of Cortical Development* ; Muscle Hypotonia ; Muscle Spasticity ; Neuronal Migration Disorders ; Paralysis ; Pseudobulbar Palsy ; Seizures

Hypertensive encephalopathy is characterized by an acute, severe rise in blood pressure associated with headache, nausea, vomiting, altered mental status, and focal neurologic deficits, and rapid improvement after control of blood pressure. An eight-year old boy had been admitted with symptoms of red urine, fever, headache, convulsion, and visual blurring of vision. Blood pressure was 140/90mmHg, and CSF exam revealed WBC 8/mm3, glucose 83mg/dL, protein 106mg/dL. Serum C3 was 8mg/dL, C4 17mg/dL, ASO 1,024 Todd units. Brain CT showed non specific findings, however, MRI revealed symmetric high signal intensity lesions on T2WI over the parieto-occipital areas bilaterally. These lesions had been completely resolved on the following MRI 4 weeks later.
Blood Pressure ; Brain* ; Fever ; Glomerulonephritis* ; Glucose ; Headache ; Humans ; Hypertensive Encephalopathy* ; Magnetic Resonance Imaging* ; Male ; Nausea ; Neurologic Manifestations ; Seizures ; Vomiting

Keratosis punctata of the palmar creases (KPPC) is rare skin condition characterized by punctiform hyperkeratotic pits confined to the palmar and digital creases. Although this condition has been regarded as a variant of classical punctate keratoses, there are some differences between classical punctate keratosis and KPPC. We herein report a case of KPPC in a 22-year-old man who had numerous, tiny, hyperkeratotic pits limited to the palmar creases of both hands with typical histologic findings.
Hand ; Humans ; Keratosis* ; Skin ; Young Adult

Ureteroscopic removal of the stone is now popular for the management of the lower ureteral stone. A clinical study was performed on our 75 patients with lower ureteral stone treated with ureteroscopy. Of the 75 stone manipulations 62 (83%) were immediately successful and the final success rate including spontaneous delivery of stone or fragment after the procedure was 87 percents (65 cases). Of 57 smaller calculi than 1 cm (radiographic largest diameter) 50 (88%) were removed successfully. Mean duration of postoperative hospitalization was 5.6 days. There were no interrelations between the success rate and anesthetic methods. Significant complications during or after procedure were not identified. We conclude that ureteroscopic removal of stones under direct vision can be done safely and be the first choice of procedure for the lower ureteral stones.
Calculi ; Clinical Study ; Hospitalization ; Humans ; Ureter* ; Ureteroscopy

Carcinoembryonic antigen(CEA) was measured by the enzyme immunoassay(EIA) technique in the serum and urine of 25 patients with non-tumor disease and 68 patients with several types of genitourinary tumor at the Department of Urology, Kyungpook National University Hospital during period from January 1982 to May, 1984. The results were as follows : 1. Mean serum and urine CEA levels in 24 normal controls were 3.97 ng/ml and 9.56 ng/ml. The upper limit of ""Normal"" for CEA levels was fixed at 2 standard deviation above the mean of normal controls. Therefore, we accept 9ng/ml and 23 ng/ml as the upper limit of normal for serum and urine 2. Mean serum and urine CEA levels in 21 patients with urinary infection were 5.70 ng/ ml and 21.14ng/ ml and incidence of positive results in serum and urine were 9.5% and 33%. Mean serum and urine CEA. levels in 68 patients with G-U tumor were 11.08ng/ ml and 49.12 ng/ ml and incidence of positive results in serum and urine were 32% and 34% 3. Mean serum and urine CEA levels in bladder ca were 13.78 ng/ ml and 60.43 ng/ ml being the highest elevation in G-U tumor, 12.74 ng/ ml and 53.60 ng/ ml in renal cell ca and 7.98 ng/ ml and 44.40ng/ ml in ureteral ca. Incidence of positive results of serum and urine in bladder ca were 38% and 38%, 23% and 38% in renal cell ca and 33% and 40% in ureteral ca. 4. Mean CEA levels and incidence of positive results in urine were correlated with the stage and grade of bladder ca. 5. Preoperative and postoperative serum and urine CEA measurements were useful in determining the completeness of tumor resection in patients with G-U tumor. However, in case of ileal conduit with cystectomy or incomplete resection of tumor mass, serum and urine CEA levels were increased postoperatively.
Carcinoembryonic Antigen* ; Cystectomy ; Gyeongsangbuk-do ; Humans ; Incidence ; Ureter ; Urinary Bladder ; Urinary Diversion ; Urology

PURPOSE: To investigate the clinical effects of orthokeratology lens wear on inhibition of the progression of Korean myopia and astigmatism. METHODS: The authors reviewed out-patient records of 144 eyes of 74 patients wearing orthokeratology lenses. The cycloplegic refraction and keratometry before and after wearing the lens were compared. The 190 eyes wearing spectacles were included into the control group. We evaluated the relationship between orthokeratology lens wear and control group according to age, initial myopia, initial astigmatism, myopic progression, astigmatic progression and duration of orthokeratology lens wearing. RESULTS: The mean cycloplegic refractive error of spherical equivalent was -3.36 +/- 1.96 diopters (D) in the patients wearing orthokeratology lenses, the mean astigmatism was -0.86 +/- 0.72 D, and the mean wearing period was 3.41 +/- 1.5 years. The mean myopic progression was 0.25 +/- 0.31 D in lens wearing, and 0.62 +/- 0.39 D in glasses wearing, respectively. There were statistically significant differences between lens and glasses wearing group (t-test, p < 0.01). The mean astigmatic progression was 0.06 +/- 0.22 D in lens wearing, and 0.15 +/- 0.21 D in glasses wearing control group respectively, and the results also show statistically significant differences (t-test, p < 0.01). There were no relationships between two groups as for age, initial myopia, initial astigmatism and duration of orthokeratology lens wearing (t-test, p > 0.01). CONCLUSIONS: The orthokeratology lens was found to be effective in suppression of the progression of Korean myopia and astigmatism, compared with the glasses.
Astigmatism ; Eye ; Eyeglasses ; Glass ; Humans ; Myopia ; Outpatients ; Refractive Errors

No abstract available.
Birth Weight ; Erythrocytes/ultrastructure ; Gestational Age ; Human ; Infant, Newborn* ; Infant, Premature* ; Prospective Studies ; Reticuloendothelial System/physiology* ; Spleen/physiology*

The purpose of this study was to compare microleakage and marginal hybrid layer in class V restorations using two one-bottle adhesives and one self-etching adhesive. Class V cavity preparations with occlusal margins in enamel and gingival margins in dentin were prepared on buccal and lingual surfaces of 30 extracted human molar teeth. Prepared teeth were randomly divided into three treatment groups (n=30) and restored with three adhesives and composites: Single Bond/Filtek Z-250 (Group 1), Prime&BondNT/Esthet.X (Group 2), UniFil Bond/UniFil F (Group 3). For microleakage, samples were stored in room temperature water for 24 hours, thermocycled, stained with 2% methylene blue dye, sectioned into halves, scored and analysed using Mann-whitney test and Wilcoxon signed rank sum test. For marginal hybrid layer, samples were sectioned into halves, treated with 10% phosphoric acid for 5 seconds, stored in 5% NaOCL solution for 24 hours, dried and gold coated. Occlusal and gingival margins of each sample were inspected under SEM. The results of this study were as follows; 1. Microleakage at the occlusal margins was not evident in group 1 and group 2, but it showed in group 3 (p<0.05). 2. Microleakage in group 1 and group 3 was significantly lower than in group 2 at gingival margins (p<0.05). 3. Microleakage at gingival margins was greater than at occlusal margins in group 1 and group 2, but microleakage at occlusal margins was greater than at gingival margins in group 3 (p<0.05). 4. In group 1 and group 2, no gaps at occlusal margins showed. But gaps showed in group 3. Occlusal margins were free from a hybrid layer in all groups. 5. The thickness of the marginal hybrid layers was 2.5~5 microm thick in group 5 microm thick in group 2 and 1.5 microm thick in group 3. 6. There was no corelation between microleakage and thickness of marginal hybrid layer. In coclusion, the effect of dentin adhesives on microleakge in class V composite restorations was excellent when one-bottle adhesives were applied on enamel margin, and it was good when a self-etching adhesive was applied on dentinal margin. There was no corelation between microleakage and thickness of marginal hybrid layer.
Adhesives ; Chimera ; Dental Enamel ; Dentin ; Humans ; Methylene Blue ; Molar ; Phosphoric Acids ; Tooth ; Water