1.Study on the nNOS Expression in the Rat Spinal Cord of the Spinal Nerve Ligation Model with Neuropathic Pain and the Dorsal Rhizotomy.
Journal of Korean Neurosurgical Society 2000;29(7):877-885
No abstract available.
Animals
;
Ligation*
;
Neuralgia*
;
Rats*
;
Rhizotomy*
;
Spinal Cord*
;
Spinal Nerves*
2.CT Findings of Paranasal Sinus Osteoma.
Young Uk LEE ; Eun Kyung YOUN ; Sang Gyeong SUH ; Sun Young NA ; Kook Jin LEE
Journal of the Korean Radiological Society 1994;30(1):27-31
PURPOSE: To evaluate the incidence and the site of osteomas and their relation to sinonasal inflammation. MATERIALS AND METHODS: 1578 PNS computed tomography (CT) of patients with symptoms of sinusitis were evaluated and correlation with plain radiographic finding was done. RESULTS: The total incidence of osteomas was 0.82%(13/1578) on plain radiography and 3.29% (52/1578) on CT. Fifty-seven osteomas were found in 1578 PNS CT, including 2 osteomas in 5 cases. The most common site was the ethmoid sinus(54%, 31/57) and the next was the frontal sinus(35%, 20/57) on CT. Forty-five osteomas (78.9%) were associated with the sinonasal inflammatory change. CONCLUSION: The total incidence of osteomas from our results was higher than previous reports. And based on the analysis of CT, the most common site was not the frontal sinus as all the previous reports stated, but the ethmoid sinus, probably by virtue of high resolution of CT and/or higher prevalence of inflammation in the ethmold sinus.
Ethmoid Sinus
;
Frontal Sinus
;
Humans
;
Incidence
;
Inflammation
;
Osteoma*
;
Prevalence
;
Radiography
;
Sinusitis
;
Virtues
3.Effect of obesity and age on the blood pressure.
Youn Jin KIM ; Young Hoon HAN ; Sang Wook PARK ; Byung Mann CHO ; Hyung Su SEOL ; Youn Jeong HEO
Journal of the Korean Academy of Family Medicine 1997;18(3):295-305
BACKGROUND: In recent years, the incidence of obesity increased in Koreans. The main cause suggested is the diet style of Korean changed to that of Western. It has been proved that obesity is a risk factor or an aggravating factor of hypertension and diabetes mellitus, cardiovascular disease, etc. Primary physician has been interested in the correlation of blood pressure with relative body weight and aging. The purpose of this study was to focus on the influence of age and relative body weight on blood pressure. METHODS: Subjects were collected from 2,068 adults who had received Adult Health Examination. That subjects were divided according to age, relative body weight and then the relation of blood pressure with age according to relative body weight and relation with relative body weight according to age were investigated. RESULTS: Systolic blood pressure increased significantly according to age in all male and female three weight groups and then increased significantly according to relative body weight in all male and female three age groups except male seventh decade group. Diastolic blood pressure increased significantly according to age in all male and female three weight groups except male obesity group and then increased significantly according to the relative body weight in all male and female three age groups except male and female seventh decade groups. Systolic blood pressure has higher correlation with age than relative body weight and diastolic blood pressure has higher correlation with relative body weight in male. In female, systolic and diastolic blood pressure have higher correlations with age. CONCLUSIONS: It can be suggested that blood pressure increase significantly according to aging process and relative body weight. These two factors have a little different effects to systolic and diastolic blood pressure according to sex. Relative body weight has more effect to diastolic blood pressure than systolic blood pressure in male.
Adult
;
Aging
;
Blood Pressure*
;
Body Weight
;
Cardiovascular Diseases
;
Diabetes Mellitus
;
Diet
;
Female
;
Humans
;
Hypertension
;
Incidence
;
Male
;
Obesity*
;
Risk Factors
4.DNA Profiling via Short Tandem Repeat Analysis by Using Serum Samples.
Ji Hyun LEE ; Hye Young LEE ; Sohee CHO ; Joo Youn CHO ; In Jin JANG ; Soong Deok LEE
Korean Journal of Legal Medicine 2013;37(4):220-223
Serum is free of cellular components. Because DNA is located in the nuclei or mitochondria of cells, serum could be assumed DNA free. Few previously published case reports to date have used serum for DNA typing. Here, we report on human genotyping via short tandem repeat (STR) analysis using serum as a sample, and discuss problems involved in the process.
DNA Fingerprinting*
;
DNA*
;
Humans
;
Microsatellite Repeats*
;
Mitochondria
5.Studies of cocktail therapy with multiple cytokines for neoplasia or infectious disease of the dog I. cDNA cloning of canine IL-3 and IL-6.
Il Seob SHIN ; Hye Ryon KIM ; Myung Jin NAM ; Hwa Young YOUN
Journal of Veterinary Science 2001;2(2):115-120
This paper describes the cloning and sequence analysis of the cDNAs encoding the canine homologues of interleukin-3 (IL-3) and interleukin-6 (IL-6). The coding sequences for canine IL-3 and IL-6 were obtained by using the reverse transcription polymerase chain reaction (RT-PCR) with RNA harvested from canine peripheral blood mononuclear cells (PBMCs). Canine IL-3 cDNA includes a single open reading frame of 432 nucleotides, which encodes a 143 amino acid polypeptide and has 44.7, 42.4, 37 and 23.7% homology with the cow, sheep, human and rat IL-3 sequences, respectively. Canine IL-6 cDNA (GenBank accession number; AF275796) encodes a putative 20-amino acid signal peptide followed by a 187-amino acid mature protein. The predicted amino acid sequence of canine IL-6 shares 60.4, 77.2, 71.0, 55.8 and 42.0% sequence identity with those of human, feline, porcine, sheep and rat IL-6, respectively.
Amino Acid Sequence
;
Animals
;
Base Sequence
;
Cloning, Molecular
;
Concanavalin A/pharmacology
;
DNA, Complementary/*chemistry
;
Dogs/blood/genetics/*immunology
;
Interleukin-3/chemistry/*genetics
;
Interleukin-6/chemistry/*genetics
;
Leukocytes, Mononuclear/chemistry/drug effects
;
Molecular Sequence Data
;
Open Reading Frames/genetics
;
Protein Sorting Signals/genetics
;
RNA/blood/genetics
;
Reverse Transcriptase Polymerase Chain Reaction/veterinary
;
Sequence Homology, Amino Acid
;
Sequence Homology, Nucleic Acid
6.Detection of Herpes Virus-6 by PCR I Cerebrospinal Fluid from Hospitalized Adult Patients with Aseptic Meningitis or Encephalitis.
Hae Kyung PARK ; So Youn WOO ; Hyun Jin KIM ; Young Hae CHONG
Journal of the Korean Society of Virology 2000;30(3):171-178
No Abstract Available.
Adult*
;
Cerebrospinal Fluid*
;
Encephalitis*
;
Humans
;
Meningitis, Aseptic*
;
Polymerase Chain Reaction*
7.The longevity of immunofluorescent antibody in the patientsconfirmed as Tsutsugamushi disease.
Jeung Hoon LEE ; Beom Jin SUNG ; Tae Young YOUN ; Woo Hyun CHANG
Korean Journal of Infectious Diseases 1991;23(1):19-23
No abstract available.
Longevity*
;
Scrub Typhus*
8.Anatomic Variations on PNS CT.
Young Uk LEE ; Jong Dae SUH ; Eun Kyung YOUN ; Dong Hyun KIM ; Kuk Jin LEE
Journal of the Korean Radiological Society 1994;31(3):431-438
PURPOSE: To illustrate frequently encountered anatomic variations on PNS computed tomography(CT) and to assess their clinical significance. MATERIALS AND METHODS: CT findings of 1523 patients, who underwent PNS CT with no history of sinus surgery, were reviewed, and prevalence of each anatomic variation and its relationship with mucociliary clearance pathway was evaluated. RESULTS: Two categories of anatomic variations were encountered. The first group included variations of the turbinates, such as concha bullosa(28.6% ), paradoxical middle turbinate(31.5%), of the uncinate process, such as medially bent or folded(36.3%), laterally bent(3.7%) or uncinate bulla(0.5%), of the ethmoidal sinus, such as Haller's ce11(28.2%), large agger nasi ce11(9.6%) or large ethmoidal bulla(23.5%) and nasal septal deviation(24. 1%), which might cause obstruction of mucociliary clearance pathway and thus give rise to secondary obstructive sinusitis. The second group included Onodi ce11(1.4%) and medial depression of the lamina papyracea (3.5%), which were not related with obstructive sinusitis. 87 cases of large agger nasi cell were associated with obstruction of nasofrontal recess. Large ethmoidal bulla(452 cases), Haller's ce11(245 cases) and true concha bullosa (25 cases) contributed to narrowing of the infundibulum. Medially bent uncinate process(220 cases), concha bullosa(157 cases), paradoxical middle turbinate(126 cases) and nasal septal deviation(93 cases) were observed in middle meatal obstruction and supreme concha (3 cases) accompanied sphenoethmoidal recess obstruction. CONCLUSION: Recognition of anatomic variations on PNS CT is important to build a treatment plan in patients with obstructive sinusitis as they may represent causes of the disease, and to avoid critical complications during functional endoscopic sinus surgery.
Anatomic Variation
;
Depression
;
Humans
;
Mucociliary Clearance
;
Prevalence
;
Sinusitis
;
Turbinates
9.UVB Induced Minimal Erythema Dose ( MED ) and Minimal Melanogenic Dose ( MMD ) in Young Adult Koreans.
Woo Seok KOH ; Jin Ho CHUNG ; Jai Il YOUN ; Young Woo SHIN
Korean Journal of Dermatology 1994;32(2):253-257
BACKGROUND: The erythemal response and delayed tanning of the skin to UV radiations which are used as diagnostic phototest and guideline of phototherapy are different according to the races and light sources. OBJECTIVE: The MED and MMD induced by UVB radiation were measured in 130 normal young adult Koreans. METHODS: In this study, a high pressure mercury are lamp(Burdick UV-800) and a sunlight fluorescent lamp(Waldmann UV 800) were used as UVB light sources. Multiple sites of the lower baek or buttock skin were irradiated with an increasing dose by a constant, anount. The minimal doses of erythema response and delayed tanning of the skin were assessed visaually at 24 hours and 7 days after irradiation, respectively. RESULTS: MED and MMD of Burdick UV-800 are 18.0+/-9.8mJ/cm2 (mean+/-S.D.), 29.7+/-12.5mJ/cm2, respectively. MED and MMD of Waldmann UV 800 are 70.8+/-28.5mJ/cm2 and 91.2+/-33.1mJ/cm2, respecively. The most frequent MED by Burdick UV-800 is 10mJ/cm2 and those by Waldmann UV 800 are 50m J/cm2 and 60m J/cm2. CONCLUSION: In this study MED and MMD of young adult Koreans by two kinds of UVB light sources were assessed. The RESULTS: how that MED is less than MMD and the levels of MED under which the photosensitivity is suggested are 5.6mJ/cm2 by Burdick UV-800 anr 32.4mJ/cm2 by Waldmann UV 800.
Buttocks
;
Continental Population Groups
;
Erythema*
;
Humans
;
Phototherapy
;
Skin
;
Sunlight
;
Tanning
;
Triacetoneamine-N-Oxyl
;
Young Adult*
10.An analysis of contents of outpatients in geriatric center.
Tai Kyung PARK ; Young Jin KIM ; Hye Ree LEE ; Bang Bu YOUN
Journal of the Korean Academy of Family Medicine 1992;13(10):800-808
No abstract available.
Humans
;
Outpatients*