Hypertrichosis has been frequently observed during the oral administration of the potent antihypertensive agent, minoxidil. However, hypertrichosis is uncommon after treatment with topical minoxidil for alopecia, and usually occurs in areas close to the site of the application. We describe a 52-year-old woman with diffuse facial hypertrichosis. She developed abnormal hypertrichosis while applying the optimal dose of 3% topical minoxidil for 2 months for the treatment of androgenetic alopecia.
Administration, Oral ; Alopecia ; Female ; Humans ; Hypertrichosis* ; Middle Aged ; Minoxidil*

Bowen's disease represents an intraepidermal squamous cell carcinoma and can be associated with internal malignancy. Internal cancers originate predominantly from respiratory, gastrointestinal, and genitourinary tracts. A 71-year-old man presented with erythematous crusted plaques with emsion on the right lower abdomen, left elbow, and left 4th finger. He had been diagnosed with small-cell lung cancer 17 months ago. The histopathologic features of the skin lesions showed Bowens disease. The abdominal lesion was removed by surgical excision and the lesions on the elbow and finger were treated by topical 5-FU application.
Abdomen ; Aged ; Bowen's Disease* ; Carcinoma, Squamous Cell ; Elbow ; Fingers ; Fluorouracil ; Humans ; Lung Neoplasms* ; Lung* ; Skin

Iron deficiency has been discussed as an etiologic factor in diffuse alopecia. Although the mechanism of alopecia related to iron deficiency remains unknown, the diagnosis is confirmed if hair loss ceases with iron administration. However, hair structure abnormalities due to iron deficiency are less known. We report a case of hair structure abnormality associated with iron deficiency anaemia. The hair structure abnormality was a fusiform and expanded node of the hair shaft. The hair loss ceased and the abnormality was corrected with iron administration.
Alopecia ; Diagnosis ; Hair* ; Iron*

No abstract available.
Adenoma* ; Toes*

Periumbilical perforating pseudoxanthoma elasticum (PPPXE) is a localized acquired disorder found most frequently in obese, multiparous, middle-aged women. It is characterized clinically by yellowish, lax, well-circumscribed, reticulated or cobblestoned patches or plaques in the periumbilical region. Multiparity, obesity, massive ascites, and abdominal surgery are thought to the initiating factors. There is controversy about the etiology of PPPXE. Some authors have classified it as a separate entity from hereditary pseudoxanthoma elasticum (PXE), while others speculate that this condition merely represents a variable expression of PXE in which systemic associations are likely. We report a case of periumbilical perforating pseudoxanthoma elasticum associated with a clinical PXE lesion on the anterior neck.
Ascites ; Female ; Humans ; Neck ; Obesity ; Parity ; Pseudoxanthoma Elasticum*

A 68-year-old male patient visited our clinic complaining of a single skin lesion on the left shoulder for 5 months. The lesion was a bluish to pigmented, bean-sized nodule. No subjective symptoms and signs accompanied it. Histologically, the tumor mass was composed tumor emboli in the vessels and moderately differentiated neoplastic glands lined by anaplastic cells. These findings were consistent with the metastatic adenocarcinoma. Abdominal sonography and CT scanning showed a mass at the tail of the pancreas. Therefore, we diagnosed this skin lesion as a metastatic adenocarcinoma originating from the pancreatic tail. We report herein a rare case of skin metastasis from pancreatic tail cancer, in which the cutaneous involvement was the first sign of the internal malignancy.
Adenocarcinoma ; Aged ; Humans ; Male ; Neoplasm Metastasis* ; Pancreas ; Pancreatic Neoplasms ; Shoulder ; Skin* ; Tail* ; Tomography, X-Ray Computed

No abstract available.
Meningitis

Vibrio cholerae strain other than O1 and O139 (Vibrio cholerae non-O1/O139) are associated with sporadic diarrhea and have often been reported in association with extraintestinal infections. We report a case of peritonitis by V. cholerae non-O1/O139 in 43-year-old male who was diagnosed cirrhosis. He, was complained of abdominal distension and fever without history of consumption of raw sea food and exposure to sea water. Gram negative bacilli were cultured from his peritoneal fluid and identified as V. cholerae sero group O14.
Adult ; Ascitic Fluid ; Cholera ; Diarrhea ; Fever ; Fibrosis ; Humans ; Male ; Peritonitis* ; Seafood ; Seawater ; Vibrio cholerae* ; Vibrio*

Vibrio cholerae strain other than O1 and O139 (Vibrio cholerae non-O1/O139) are associated with sporadic diarrhea and have often been reported in association with extraintestinal infections. We report a case of peritonitis by V. cholerae non-O1/O139 in 43-year-old male who was diagnosed cirrhosis. He, was complained of abdominal distension and fever without history of consumption of raw sea food and exposure to sea water. Gram negative bacilli were cultured from his peritoneal fluid and identified as V. cholerae sero group O14.
Adult ; Ascitic Fluid ; Cholera ; Diarrhea ; Fever ; Fibrosis ; Humans ; Male ; Peritonitis* ; Seafood ; Seawater ; Vibrio cholerae* ; Vibrio*

No abstract available.
Humans