Colorectal cancer is treated primarily by surgery. The goal of surgery is to completely remove the tumor. Surgery for carcinoma of the colon is aimed at removing the tumors with an adequate margin by a wide excision of the tumor-bearing area and associated lymphatics, with attention to the blood supply to the segment and creation of anastomosis without tension. Both rectal and colon cancers are resected for the purpose of cure and prevention of spread and local or pelvic recurrence. The operations generally employed for cancers above the rectum include right colectomy, transverse colectomy, left colectomy, anterior resection, subtotal colectomy, and total colectomy. More limited resections are occasionally performed for palliation in patients with distant metastasis. The survival benefits from the no-touch technique and radical lymphadenectomy with high ligation are still controversial. In rectal cancer, 2 ㎝ is sufficient for the distal resection margin. Several reports have demonstrated improvement in local recurrence rates and cancer-specific survival rate through TME (total mesorectal excision). The technique of chemosensitized irradiation was successful in down staging the tumors and in reducing the tumor size. Preoperative chemoradiation therapy and coloanal anastomosis enables the sphincter-preserving operation more frequently. The rectum, genitourinary structures, and the pelvic autonomic nervous system are very closely related. The urinary and sexual function can be preserved by nerve-sparing operation for rectal cancer. The anorectal function might be improved by colonic pouch operation. Transanal excision or trananal endoscopic microsurgery are advocated for the definitive treatment of small, exophytic, well differentiated, mobile lesions. Resection of hepatic or pulmonary metastasis in cases with-out contraindications improves the survival.
Autonomic Nervous System ; Colectomy ; Colon ; Colonic Neoplasms ; Colorectal Neoplasms* ; Humans ; Ligation ; Lymph Node Excision ; Microsurgery ; Neoplasm Metastasis ; Rectal Neoplasms ; Rectum ; Recurrence ; Survival Rate

No abstract available.
Animals ; Ligation* ; Neuralgia* ; Rats* ; Rhizotomy* ; Spinal Cord* ; Spinal Nerves*

No abstract available.
Coal* ; Mucous Membrane*

No abstract available.
Stomach Neoplasms*

No abstract available.
Cardioplegic Solutions* ; Heart Diseases* ; Heart* ; Hemodynamics* ; Humans

We report the clinical evolution of two elderly male patients with extramammary Paget's disease who were treated with radiotherapy. Both cases primarily involved the scrotum and penile root, and were not associated with any underlying or visceral malignancy. The total doses administered were 6000 cGy and 3000 cGy, respectively. A good clinical response was achieved in both cases. No major side effects were observed. The patients are being followed for any signs of recurrence and have been completely asymptomatic to date
Aged ; Humans ; Male ; Paget Disease, Extramammary ; Radiotherapy* ; Recurrence ; Scrotum

We report a case of tuberculosis verrucosa cutis in a 33-year-old male patient who presented with mild itching verrucous plaque over the perineum. The Mantoux test revealed a positive reaction. The histophathologic picture consists of slight hyperkeratosis, irregular ac:anthosis overlying an inflammatory iafitrate in the dermis. Tuberculous granulomas with caseation necrosis were seen in the dermis. Tuber clebacillus was demonstrated. The patient was treated with Isoniazid, Rifampicin, and Pyrazine made for 6 months. To date, the skin lesions have markedly improved.
Adult ; Dermis ; Granuloma ; Humans ; Isoniazid ; Male ; Necrosis ; Perineum ; Pruritus ; Rifampin ; Skin ; Tuberculosis*

No abstract available.
Evaluation Studies as Topic* ; Hoarseness*

This authors reviewed the radiographs of 20,057 patients with spinl radiculomyelopathy from April 1983 August 1990. The incidence and distribtion of the ossification of the spinal ligaments were analized as following. 1) The overall incidence of spinal ligaments ossification was 3.6% among 20,057 patients. 2) The most frequently occurs at lumbar area(67.1%), and then cervical(27.5%) thoracic(0.4%) area as in orders. 3) The OPLL was most common type(2.19%) of these spinal ligaments ossification, and then OALL(0.7%), OLF(0.24%) as in orders. 4) OPLL (1) OPLL was most frequent at lumbar area(58.6%) and then cervical(37.0%), thoracic(0.4%) area as in orders. (2) The cervical OPLL was commonly found at C5 & C6 area and morphologically, the multiple segmented type was most common then continuous type, mixed type and single segmented type in orders. (3) The multiple segmented type was more frequently found at upper cervical area, but the continuous type was more frequent at lower cervical area. 5) OALL (1) OALL was most frequent at lumbar area(86.0%) but thoracic(1.4%) and cervecal area(5.3%) were relatively low in frequency. (2) Of the lumbar OALL, the L4/5 area was most frequent site(37.8%) but the L3/4(25.3%) and L5/S1 area(24.5%) also had relatively high occurance rate. 6) OLF (1) OLF was most frequent at lumbar area(92.7%), but the incidence of OLF was relativerly rare at cervical(2.1%) and thoracic area(5.2%). (2) Of the lumbar OLF, the L4/5 area was most common site(33.1), but L5/S1 area had also high occurance rate(27.2%).
Humans ; Incidence ; Ligaments*

Nicotine is a water-soluble alkaloid extracted from tobacco plants, and most frequently encountered in snuff, chewing tobacco, cigarettes, cigars and pipe tobacco or in a limited number of pesticides. Nicotine overdose or poisoning might be serious or fatal and lead to death; caused by cardiovascular arrest, respiratory muscle paralysis, and/or central respiratory failure due to its toxic effect. Suicide by nicotine ingestion has been rarely reported due to emetic response. We present a case of suicidal nicotine poisoning. A 56-year-old man was found dead and the postmortem examination revealed no injury or disease. We confirmed a high concentration of nicotine in the toxicological test. Through scene investigation, we determined this case as a suicidal nicotine poisoning.
Autopsy ; Eating ; Humans ; Middle Aged ; Nicotine* ; Pesticides ; Poisoning* ; Respiratory Insufficiency ; Respiratory Paralysis ; Suicide ; Tobacco ; Tobacco Products ; Tobacco, Smokeless