Incontinentia pigmenti achromians (Ito) begins during childhood and is characterized by progressive appearance of bizarre patchy or whorl-like hypopigmentation without any preceeding or associated inflammatory changes in a fashion that resembles a negative piture of pigmentation in patients with incontinentia pigmenti. Mental, bony and ocular symptoms are not infrequently found in association with incontinentia pigmenti achromians. The incidence is high in the female sex, and there is no hereditary background. A 24-year-old Korean soldier was first seen in May 1974 in dermatologic clinic of Capital Armed Forces General Hospital. Bizarre, reticulated, linear and whorllike hypopigmented macular lesions were noted. On the skin of the trunk and both extremities. The lesions started at the age of 4 year and developed without any inflarnmatory signs Family history did not disclose any type of pigmentation The disorder, and mental, bony and occular manifestations were not found. Biopsy specimen demonstrated that the amount of melanin in the basal layer was decreased in the hypopigmented area, and reveals neither inflammatory changes nor dropping off of melanin granules into the dermis.
Arm ; Biopsy ; Dermis ; Extremities ; Female ; Hospitals, General ; Humans ; Hypopigmentation ; Incidence ; Incontinentia Pigmenti ; Melanins ; Military Personnel ; Pigmentation ; Pigmentation Disorders ; Skin ; Young Adult

A 77-year old man living in Kyunggi-Do, Korea was surgically treated at Seoul National University Hospital on April 1981, because of acute abdomen. At laparotomy, a 1.77m long adult Taenia saginata was found both in gallbladder and in common bile duct to cause acute gangrenous cholecystitis. The relevant literature were reviewed and possible mechanisms of the disease were discussed.
parasitology-helminth-cestoda ; Taenia saginata-taeniasis ; case report ; gallbladder ; common bile duct ; acute abdomen ; laparatomy

No abstract available.
Adolescent* ; Humans ; Liposarcoma* ; Neck*

No abstract available.
Child* ; Humans ; Melanoma*

The advent of the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates a thorough study of the stability and transmissibility in the environment. We characterized the stability of SARS-CoV-2 in three water matrices: fresh, tap, and seawater. The minimum infective dose of SARS-CoV-2 in Vero cells was confirmed to be 10 3 PFU/mL. The stability of SARS-CoV-2 varied according to the water matrix: infective SARSCoV-2 was undetectable after treatment with fresh water and seawater, but remained detectable for 2 days in tap water, when starting with an initial concentration of 10 4 PFU/mL. When the starting concentration was increased to 10 5 PFU/mL, a similar trend was observed. In addition, viral RNA persisted longer than infectious virus in all water matrices. This study was conducted in stagnant water containing a significantly high titer of virus, thus, human-to-human transmission of SARS-CoV-2 through the actual aquatic environment is expected to be rare.

No abstract available.
Keloid*

No abstract available.
Common Variable Immunodeficiency* ; Cytomegalovirus Infections* ; Cytomegalovirus* ; Immune System Diseases

Juvenile hyaline fibromatosis is a rare disorder probably inherited as an autosomal recessive trait. It is characterized by multiple slowly growing subcutaneous nodules, hypertrophy of gingiva, flexion contracture, and radiolucent bone destruction. The histological features of the tumor-like lesions are characterized by the deposition of amorphous hyaline material in which spindle shaped cells are embedded. We report a case of juvenile hyaline fibromatosis in a 26 year-old-woman. She had multiple subcutaneous nodules in scalp, ear, forearms, right knee, and back. Surgical excision of the tumors in the scalp and ear was done. The largest one measured 13 9 6 cm, and had homogeneous, grayish yellow cut surface with calcification. Light microscopic examination showed abundant eosinophilic hyaline material with extensive calcification and metaplastic bone formation. Spindle cells were rarely observed at the periphery of the tumor. Hyaline matrix was PAS positive, diastase resistant, and alcian blue negative. Scattered spindle cells were positive for vimentin but negative for S-100 protein and smooth muscle actin. There were many reports regarding early lesions of juvenile hyaline fibromatosis; however in this patient, tumor existed for more than 20 years and the histology was somewhat different from the early lesions reported in the literature.
Actins ; Adult* ; Alcian Blue ; Amylases ; Contracture ; Ear ; Eosinophils ; Forearm ; Gingiva ; Humans ; Hyalin ; Hyalinosis, Systemic* ; Hypertrophy ; Knee ; Muscle, Smooth ; Osteogenesis ; S100 Proteins ; Scalp ; Vimentin

Xeroderma pigmentosum is characterized by sunlight sensitivity, autosomal recessive inheritance, and multiple cutaneous malignant melanoma, angiosarcoma and fibrosarcoma. Some patient also demonstrate neurological manifestations, ie, mental deficiency, microcephaly, ataxia, choreoathetosis, and deafness. A 22 year old Korean soldier was seen at the Capital Armed Forces General Hospital in May of 1974 because of pigmentation and ulceration on the exposed area. Since the age of 3, the patient has suffered from freckles on exposed area and the lesions were gradually increased in number. About 3 years ago, he observed nodule on the left side of face, which underwent ulceration eventually. There were no history of unconsciousness, convulsion or other neurological symptoms. The histopathological picture in the margin of ulcerated lesion revealed hyperkeratosis and acanthosis in epidermis, and masses of various shaped and sized composed of basalioma cells in dermis. The peripheral cell layer of the tumor masses showed pallisade arrangement of the nuclei.
Arm ; Ataxia ; Deafness ; Dermis ; Epidermis ; Fibrosarcoma ; Hemangiosarcoma ; Hospitals, General ; Humans ; Ichthyosis* ; Intellectual Disability ; Melanoma ; Melanosis ; Microcephaly ; Military Personnel ; Neurologic Manifestations ; Pigmentation ; Seizures ; Sunlight ; Ulcer ; Unconsciousness ; Wills ; Xeroderma Pigmentosum* ; Young Adult

The Becker's nevus (pigmentary hairy edidermal nevus) is a variety of epidermal nevus in which epidermal thickening may be minimal, and hairiness and pigmentation obvious. Characteristically it is a unilateral lesion of the shoulder in males but it may affect other sites, be multiple and bilateral, and be found in women and negroes. Histologically nevus cells are not seen in the dermis. A man aged 25 had the nevus covering extensive area on his right shoulder since 2 years ago. The pigmentation was dark brownish and hairy. The pigmented area was noninfiltrated and in place showed perifollicular darkening. Coarse hairs were noticed since a year. ago. The histopathological picture showed hyperkeratosis, acanthosis, papillomatosis and increased melanin pigments in the basal cell layer. Nevus cells were not seen in the dermis.
African Continental Ancestry Group ; Dermis ; Female ; Hair ; Humans ; Male ; Melanins ; Nevus* ; Papilloma ; Pigmentation ; Shoulder