Epdemiological studies were done on 721 patients detected and confirmed as leprosy patients at the Department of Dermatology at Chonnam University Hospitai in the ten years period from l969 to 1978. Statistically, 491 cases were male and 230 cases were female, comprising 2. 1% of the total number of outpatients (34, 631) and showing a decreasing yearly tendency, The percentage of each group, or type; tuberculoid, borderline, lepromatous and indeterminate, was 53.8%, 9.6%, 31.2%, and 5.4%, respectively. The most common age at discovery for males was 30 39 and for female 20~29 with the largest group being adults aged 20~49, 482 cases (66.9%). The sex ratio was 2.1: l, male to female. However, for the tuberculoid types the ratio was 2.5: 1 which was higher than that of the lepromatous type, I. 7: 1, By disease type the most common age group was 20 29 for tubercekid type, 30 39 for lepromatous and borderline group and 10~19 for the indeterminated group. Geographically, 652 cases(90. 4%) were from Chonnam Province and 61 cases (8.5%) from Chonbuk Province. We also observed some significant sequential changes of the type of disease descovered even though 10 years is a relatively short period. There was a tendency towards decreased detection of the tuberculoid type and increased detection of the borderline an.d indeterminate group.
Adult ; Dermatology ; Female ; Humans ; Jeollabuk-do ; Jeollanam-do ; Leprosy* ; Leprosy, Paucibacillary ; Male ; Outpatients ; Sex Ratio

No abstract available.
Child* ; Humans ; Infant* ; Peptic Ulcer*

The subjects of the present study were 111 patients admitted to a hospital and 304 healthy people living in similar condition. A self report symptom inventory, SCL-90(symptom check list-90) was used and the two groups were analysed and compared by many factors. The results of theis study are as follows. 1. All dimensional values of the psoriasis group were much higher than the normal healthy group. In order of significance: depression, anxiety, obsessive-compulsive, psychotism, interpersonal sensitivity, hostility, and somatization(all p<0.01). This result indicates a significantly heightened incidence of psychological problems among psoriatic patients. 2. There were significant differences between each clinical type. As a whole, common and pustular types showed highter dimensional scores than guttate type. 3. In the psoriasis group, subjects over 30 years old had higher scores except in somatization and paranoid ideation dimensions. However there was no significant relationship between age and dimensional scores. 4. Female psoriatic patients showed higher values than male patients on all dimensions excopt paranoid ideation. T verification showed significance in depression and hostility (p<0.05). 5. Analysed by marital status, generally unmarried patients had higher dimensional scores than married patients, but there was no significant differences. 6. In contrast with the control group, psoriatic patients of low educational status showed higher dimensional scores than patients of high educational status. 7. Analysed by job at onset of disease, student patients showed the lowest scores. There were significant differences for somatization(p<0.01) and paranoid (p<0.05) dimensional scores. 8. Analysed by the age of onset of disease, the patients who developed psoriasis before 20 years of ages showed higher dimensional scores than the patients, after 20 years of age. 9. Compared according to duration of the disease, dimensional scores rose in patients under 1 year duration decreased in patients of 1 to 2 years' duration and rose again in parients over 3 years' duratio. 10. As the accuracy of understanding about the disease decreased, the dimensional scores tended to be higher.
Adult ; Age of Onset ; Anxiety ; Depression ; Educational Status ; Female ; Hostility ; Humans ; Incidence ; Male ; Marital Status ; Psoriasis ; Self Report ; Single Person

We studied skin thickness of the twelve body sites in 25 post-mortem subjects. The most thinnest and thickest sites of the skin layers are as follows(unit: um) l. In the horny layer, eyelid(13.16+/-5.44) and sole(420.83+182. 25), respectively 2. In the granular, eyelid, posterior ear, abdomen, back, thigh, forearrn(1 layer)and sole(3.4+/-0.59 layers), respectively 3. In the prickle cell layer(to rete ridge), forearm(50. 21+/-15. 36) and sole (174.72+/-84.41), respectively 4. In the prickle cell layer(to papillary dermis), abdomen (33. 05+/-10. 28) and sole (106.13+/-73.62), respectively 5. In the epidermis, eyelid (61.60+/-16.53) and sole (972.00+/-228. 16), rpspectively 6. In the dermis, eyelid(878.08+283. 56) and back(3596.05+/-1306.80), respectively.
Abdomen ; Dermis ; Ear ; Epidermis ; Eyelids ; Skin* ; Thigh

Livedo reticularis with summer ulceration was first reported by Feldaker et al in 1955, that is characterized by livedo reticularis and ulcerations of the legs or feet beginning primarily the summer or warmer months of the year, and healing the winter months. A 32-year old rnan has suffered from periodic painful ulcerations, which were occurred during the summer, on the both ankles and brown to bluish colored reticulated discoloration on the lower legs for about 10 years. Histopathological findings showed endothelial proliferation and partial occlusion of the dermal capillaries, fibrinoid material on the superficial blood vessels, and partial epidermal necrolysis. This patient. was treated with antiplatelet aggregating medications and antihypertensive drug.
Adult ; Ankle ; Blood Vessels ; Capillaries ; Foot ; Humans ; Leg ; Livedo Reticularis* ; Ulcer*

From September 1983 to August 1984, the clinical observations regarding cutaneous manifestations of 26(j cases of in-patients in the Department of Internal medicine with hepatic problems were observed at the Department of Derrnatology in Chonnam University Eiospital, The results were as follows: In the 266 patients, 201 patients(75.6%) revealed various cutaneous manifestaiions; Among them vascular spider occured in 100 (37. 6%), bleeding tendency in 67(25. 2%), pruritus in 65(24.4%), jaundice in 59 (22.2%), palmar erythema in 59(22. 2%), and melanosis in 56(21. l%). The incidences of skin changes by pattern of liver disease were as follows; In acte hepatits, prurit;us(46.8%) and acute urticarial & maculapapular eruption(36. 4%) were found in order. In chronic hepatitis, vascular spider(42. 6%) and melanosis (27. 9%) in order. In cirrhosis, vascular spider (62. 5%) and bleeding tendency (42. 0%) in order. In hepatic cancer vascular spider (24. 2%) and jaundice (21. 2%) in order. There were no statistically significant differences in sex distribution. In the incidences of skin changes by age groups, jaundice(p<0. 01) and melanosis were more frequently observed in the patients under the age of 29 and vascular spider (p<0.01 ) and melanosis in the patients are the age of 50. The longer the duration of illness were, the higher the incidences of skin changes except jaundice were.
Erythema ; Fibrosis ; Hemorrhage ; Hepatitis, Chronic ; Humans ; Incidence ; Internal Medicine ; Jaundice ; Jeollanam-do ; Liver Diseases ; Liver Neoplasms ; Melanosis ; Pruritus ; Sex Distribution ; Skin Manifestations* ; Skin* ; Spiders

Etretinate is a synthetic retinoic acid which has been reported effective in hyperkeratotic disorders. Recently, it has also been tried, on a limited number, for the treatment of viral wart. A 33-year-old male patient presented with multiple, tender, confluent, verrucous lesions on the scalp, both hands and feet of 4 years duration. Before coming to us, he had been treated with intralesional injection of bleomycin and electrodesiccation with little effect. We started etretinate therapy in a daily dose of 70mg(1mg /kg). After 3 weeks treatment, most of his skin lesions were flattened and softened: but an abrupt elevation of serum aminotransferases was noticed, which was normalized soon after cessation of medication. Unfortunately, the drug stop page aggravated most of skin lesions. After two weeks of withdrawal we started again the drug in a daily dose of 30mg and observed a good response without hepatic dysfunction.
Acitretin* ; Adult ; Bleomycin ; Etretinate* ; Foot ; Hand ; Humans ; Injections, Intralesional ; Male ; Scalp ; Skin ; Transaminases ; Tretinoin ; Warts*

During a 10-year period from Jan, 1970 to Dec. 1979, 33 cases of systemic lupus erythematosys were observed clinically at the Department of Dematology, Chonnam University Hospital. Statistieally, 13 cases were male and 20 chses firnale for a sex ratio of 1: l. 5. The most common age group at eatimated onset was 10-19 and the mean age was 27, 3. There were 5 cases under the age of 15 comprising 15. 2, of all cases. There was no seasonal variation at the onset of disease. Facial lesions were the most common initial sign or symptom and chief cornplaint. During the course of the illness, varions manifeatations were obaerved: artbralgia, 87. 9%; weakness and fatigue, 84. 8%; fever, 75. 8%; cutaneous lesions, 100. 0% gastrointestinal symptoms, 54. 5%; pulmonary symptoms, 42. 4%; cardiae abnomalities, 36. 4%; enlargement of reticuloendothelial systems, 30.3%; and neuropsychiatric symptom., 30. 3%. Upon laboratory analysis we found 14 cases of lupoid hepatitis and 8 cases of lupus nephritis. There were various associated diseases such as retinopathy, congestive heart failure, pulmonary tuberculosis, diabetes mellitus, etc.
Cardia ; Diabetes Mellitus ; Fatigue ; Fever ; Heart Failure ; Hepatitis ; Humans ; Jeollanam-do ; Lupus Erythematosus, Systemic* ; Lupus Nephritis ; Male ; Mononuclear Phagocyte System ; Seasons ; Sex Ratio ; Tuberculosis, Pulmonary

No abstract available.
Breast Neoplasms* ; Breast* ; Neoplasm Metastasis*

With the aging process, the senile lids are manifested by the excessive skin, decreased height of palpebral fissures with interference of the vision. Sometimes these patients often complained the blepharitis on the lateral canthal area and phtophobia. But there are many diseases to differentiate from senile lids such as dermatochalasia, blepharochalasia, hypertrophy of orbicularis oculi, herniation of orbital fat, myasthenia gravis, and blepharoptosis. Blepharospasm must also be differentiated because of sysmptoms similar to the above described senile lids. Essential blepharospam is an idiopathic progressively debilitating desease which involve bilateral spasm of the orbicularis oculi. So just only an conventional blepharoplasty could not get an improvement of symptoms and some times it makes the symptoms worsen. This case report is about blepharospasm patients visiting for blepharoplasty. And the patients got relatively the satisfied results with the injection of botulinum A toxin, aided by neurologist, instead of blepharoplasty. In conslutions, The blepharospasm in required to detect in preoperative evaluation for blepharoplasty. Once the blepharospasm is diagnosed, it is better to cooperate with neurologist and to do the blepharoplasty.
Aging ; Blepharitis ; Blepharoplasty* ; Blepharoptosis ; Blepharospasm* ; Botulinum Toxins ; Botulinum Toxins, Type A ; Humans ; Hypertrophy ; Myasthenia Gravis ; Orbit ; Skin ; Spasm