1.Long term results and clinical evaluation of lung cancer.
Jae Hyun CHANG ; Jae Ho CHO ; Jin Woo CHANG ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):463-469
No abstract available.
Lung Neoplasms*
;
Lung*
2.Clinical evaluation of 32 cases aortocoronary bypass with saphenous vein.
Jae Hyun CHANG ; Jin Woo CHANG ; Jae Ho CHO ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):452-456
No abstract available.
Coronary Artery Bypass*
;
Saphenous Vein*
3.Surgical treatment of pulmonary aspergillosis.
Jae Ho JO ; Jin Woo CHANG ; jae Hyun CHANG ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(5):380-383
No abstract available.
Pulmonary Aspergillosis*
4.Double bridge PAP labelling of fibronectin in paraffin processed tissue.
Douk Ho HWANG ; Young Seok KIM ; In Yup CHANG ; Wang Jae LEE ; Ka Young CHANG
Korean Journal of Anatomy 1991;24(2):260-167
No abstract available.
Fibronectins*
;
Paraffin*
5.The effects of acute exercise on plasma concentration of follicular stimulating hormoen(FSH), estradiol, progesterone in women.
Si Young JUNG ; Hee Kyung CHOI ; Young Soo JIN ; Jae Sik SHIM ; Chang Jae LYU
Korean Journal of Obstetrics and Gynecology 1993;36(7):2843-2856
No abstract available.
Estradiol*
;
Female
;
Humans
;
Plasma*
;
Progesterone*
6.Comparison of Oxygenation and Lung Damage of High Frequency Flow Interruption to Conventional Ventilation in Surfactant Deficient Rabbits.
Chang Keun KIM ; Churl Young CHUNG ; Hye Jae CHO
Journal of the Korean Pediatric Society 1995;38(5):591-601
No abstract available.
Lung*
;
Oxygen*
;
Rabbits*
;
Ventilation*
7.Mannitol induced acute oliguric renal failure.
Young Mi CHUNG ; Jae Seung LEE ; Chang Jun COE
Journal of the Korean Pediatric Society 1991;34(6):857-862
No abstract available.
Acute Kidney Injury
;
Mannitol*
;
Renal Insufficiency*
8.Manic patients with delusions or hallucinations.
Hee Cheol KIM ; Young Nam PARK ; Jae Chang HA
Journal of Korean Neuropsychiatric Association 1992;31(1):93-105
No abstract available.
Delusions*
;
Hallucinations*
;
Humans
9.Restoration of Hormone Dependency in Estrogen Receptor - Lipofected MDA-MB-231 Human Breast Cancer Cells.
Young Jin SUH ; Jae Hee CHANG ; Chung Soo CHUN
Journal of the Korean Cancer Association 1999;31(3):473-482
PURPOSE: The loss of estrogen and progesterone receptors appeats to be associated with a progression to less differentiated and hormone-independent tumors. The gain of hormone independency over time even in estrogen receptor-positive tumors has become another obstacle to endocrine therapy for breast cancer. We tried to regain the hormone dependency in estrogen receptor-negative breast cancer cells by lipofecting estmgen receptor cDNA. MATERIALS AND METHODS: The mutant human estrogen receptor cDNA (pSGS-HEO) was lipofected into estrogen receptor-negative human breast cancer cell line MDA-MB-231, in an attempt to restore their sensitivity to antiestrogen. Then the effects of 17p-estradiol and tamoxifen were studied by counting viable cell numbers after treating the lipofected cell line with either one or together. RESULTS: Culture medium cantaining phenol red, a weak estrogen, has growth advantages compared with culture medium without it. In both culture conditions, cell growth was most profoundly inhibited in 4 days after lipofection with mutant human estrogen receptor cDNA, which was overcome after that day. Tamoxifen, as an antiestrogen, showed a growth inhibitory effect slightly stronger tban combined conditions of tamoxifen and 17- estradiol compared to estrogen-treated group and to control, and the inhibitory effect was lasted 4 days. CONCLUSION: The temporary induction of estrogen receptor by lipofection with pSGS-HEO on estrogen receptor-negative human breast cancer cell line MDA-MB-231 showed negative growth control on these cells by tamoxifen, indicating that liposome-mediated estrogen receptor transfection may be used as a novel therapeutic strategy for hormane independent human breast cancers in the near future.
Breast Neoplasms*
;
Breast*
;
Cell Count
;
Cell Line
;
DNA, Complementary
;
Estradiol
;
Estrogen Receptor Modulators
;
Estrogens*
;
Genetic Therapy
;
Humans*
;
Phenolsulfonphthalein
;
Receptors, Progesterone
;
Tamoxifen
;
Transfection
10.Short-term outcome in manic patients with delusions or hallucinations.
Hee Cheol KIM ; Young Nam PARK ; Jae Chang HA
Journal of Korean Neuropsychiatric Association 1992;31(4):697-707
No abstract available.
Delusions*
;
Hallucinations*
;
Humans
Result Analysis
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