Traumatic dislocation of the knee is an uncommon but serious injury associated with extensive soft tissue damage and the danger of neurological and vascular involvement. During the periods from September 1983 to September 1992, we had experienced 21 cases of the traumatic dislocation of knee at the Guro and Ansan Hospital, Korea University College of Medicine. The results obtained from this study were as follows ; 1. The age of initial dislocation varied from 11 to 79 years with the average of 32. 8 years and the ratio of male to female was 20: 1. 2. Dislocations were classified into 5 types which were anterior in 9, posterior in 4, medial in 1, lateral in 4 and rotatory in 2 cases and also unclassified in 1 case. 3. Causes of the injury were traffic accident in 9, sports injury in 7, fall down in 4 and industriai injury was 1 case. 4. Complications of traumatic dislocation of the knee included popliteal artery rupture in 3, compartment syndrome in 2 and peroneal nerve palsy in 4 cases. 5. All of ligamentous injuries were repaired and augmented except 2 cases which were treated conservating 10-14 days after trauma and all of the cases of arterial injuries were repaired with an autogenous vein graft. 6. Results were excellent 3, good 12, fair 4, and poor 2 cases by Marvin classification at the average 27 months after operation. 7. Prompt completion of vascular repair is critical to avoid amputation and also operative repair of injured ligaments seems to be good method to yield good results with the improved stability.
Accidents, Traffic ; Amputation ; Athletic Injuries ; Classification ; Compartment Syndromes ; Dislocations ; Female ; Gyeonggi-do ; Humans ; Knee ; Korea ; Ligaments ; Male ; Methods ; Paralysis ; Peroneal Nerve ; Popliteal Artery ; Rupture ; Transplants ; Veins

Operative internal fixation of femoral fractures is widely accepted as the best method of treatment but the techniques are by no means devoid of complications, nor are they simple to execute. A method of treatment must be based on the analysis of the :"personality of the fracture", that is, the nature of the fracture and of patient. Mechanical failure such as metal failure, loosening of screw or nail after internal fixation, residual deformity, and nonunion, may impose serious problems on the surgeon and patient unless treatment is appropriate. The authors analyzed 14 mechanical failures of internal fixation in 12 femoral fractures from Dec. 1987 to Aug. 1992 in the department of orthopedic surgery, Ansan Hospital Korea University to study the possible cause of mechanical failure of internal fixation and pursue the way of reducing that complications and obtained the following results. 1. Eleven were males and one was female, most of them were in age of active life. 2. The level of fractures in 12 femorals were subtrochanteric in two, shaft in nine and supracondylar in one. 3. The time interval between internal fixation and failure in 10 failures was 5.5 months on average(range, 3month to 11months). It was uncertain in 4 failures. 4. Mechanical failure were presented as breakage in five plates, loosening of screw in five plates, loosening of screw in two DCP fixation, loosening of nail in one interlocking nail, bending of nail in one Kuntscher nail, one breakage and one bending in two condylar buttres plates, and cutting-out of hip screw in three compression hip screw. 5. The causes of failure were presumed to be improper surgical technique in 7 failures, inadequate selection of internal fixatives in 5 failures, and inadequate postoperative care in 1 case.
Congenital Abnormalities ; Female ; Femoral Fractures ; Fixatives ; Gyeonggi-do ; Hip ; Humans ; Korea ; Male ; Methods ; Orthopedics ; Postoperative Care

The present study was performed to evaluate the effect of Tetracycline-HCl and Saline on the change of implant surface microstructure and surface roughness according to application time. Implants with resorbable blasting media surface were utilized. Before test all 13 implants were measured surface roughness. Among them, 6 implants were rubbed with 50mg/ml Tetracycline-HCl solution and other 6 implants with saline for 1/2min., 1min., 1 1/2min., 2min., 2 1/2min and 3min. Then, specimens were processed for scanning electron microscopic observation and surface roughness after test. The results of this study were as follows. 1. Control group showed a few irregular, rough, uneven surface with crater-like depression. 2. The test group with Tetracycline-HCl conditioning showed an altered surface when Tetracycline-HCl was applied for 30secs, and showed a various surface alteration as application times go on. 3. The test group with Saline conditioning showed no significant surface differences and surface roughness. 4. The significant increase of Ra value was showed when Tetracycline-HCl was applied for 30secs. In conclusion, the 50mg/ml Tetracycline-HCl must not be applied for the RBM surface implant for surface treatment.
Depression

The present study was performed to evaluate the effect of Tetracycline-HCl on the change of implant surface microstructure according to application time. Anodic oxidation surface were utilized. Implant surface was rubbed with 50mg/ml Tetracycline-HCl solution for 1/2min., 1min., 1 1/2min., 2min., 2 1/2min. and 3min. respectively in the test group. Then, specimens were processed for Ra Value test and scanning electron microscopic observation. The results of this study were as follows. 1. The anodic oxidation surface roughness tests don't show significant difference on conditioning with saline and Tetracycline-HCl. 2. The anodic oxidized surfaces showed the craterous structures. The surface conditioning with Tetracycline-HCl didn't influence on its micro-morphology. In conclusion, Anodic oxidation implant surface is stable to detoxificate with 50mg/ml Tetracycline-HCl of implant surface.

The earliest reports of the use of electrical energy to directly stimulate bone healing seem to be in 1853 from England, the techniques involved the introduction of direct current into the non-united fracture site percutaneously via metallic needles, with subsequent healing of the defect. One endpoint of the periodontal therapy is to generate structure lost by periodontal diseases. Several procedural advances may support regeneration of attachment, however, regeneration of alveolar bone does not occur consistently. Therefore, factors which stimulate bone repair are areas for research in periodontal reconstructive therapy. Effects of cytokines or growth factors on bone repair are examples of such areas. Another one is electrical current which occurs in bone naturally, so that such bone may be particularly susceptible to electrical therapy. The purposes of this study were to observe the effects of electrical stimulation on the normal periodontium, to determine whether the electricity is the useful means for periodontal regeneration or not. Forty rats weighted about 100 gram were used and divided into 4 groups, the first group, there was no electrical stimulation with the connection of electrodes only. In the second group, there was stimulated by the 10 mA during 10 minutes per a day, in the third group was stimulated by the 25 mA , and the fourth by the 50 mA. At 3, 5, 10 and 15 days post-appliance , two rats in each group were serially sacrificed. and the maxillae and the mandible processed to paraffin, and the specimens were prepared with Hematoxylin-Eosin stain for the light microscopic evaluation. The results of this study were as follows : 1. There was the distinct reversal line on the lingual alveolar crest, whereas a little changes in the labial alveolar crest to the duration and amount of currents. 2. In 50 mA group, the cells were highly concentrated at the apex of anterior teeth, and was observed the necrotic tissue. In posterior root apex, the hypercementosis was appeared, and newly formed cementum layer has been increased continuously with the time. 3. The periodontal ligament fiber and Sharpey's fiber were arranged in order, and the bone trabeculae were increased as the experiment proceeded by, relatively the bone marrows were decreased. 4. In the pulp tissue, the blood vessels were increased with blood congestion in the experimetal specimens remarkably, and the dentinal tubules were obstructed . 5. The osteoblasts in alveolar bone proper had been showed highly activity, and also observed the formation of bone trabeculea. In the conclusion, it was suggested that the electrical stimulation has influence on the periodontium and the pulp tissue. However, there might be the injurious effects.
Animals ; Blood Vessels ; Bone Marrow ; Cytokines ; Dental Cementum ; Dentin ; Electric Stimulation* ; Electricity ; Electrodes ; England ; Estrogens, Conjugated (USP) ; Hypercementosis ; Intercellular Signaling Peptides and Proteins ; Mandible ; Maxilla ; Needles ; Osteoblasts ; Osteogenesis ; Paraffin ; Periodontal Diseases ; Periodontal Ligament ; Periodontium* ; Rats ; Regeneration ; Tooth

Metastatic spinal cord compression is one of the most dreaded complications of metastatic cancer. This type of compression can lead to pain, neurological deficits and a reduction in the patient's quality of life. A case of rapid progression and extension of a metastatic epidural mass from clear cell adenocarcinoma of the kidney in a short period after surgical decompression is reported, along with a literature review.
Adenocarcinoma, Clear Cell ; Decompression, Surgical ; Kidney ; Neoplasm Metastasis ; Quality of Life ; Spinal Cord Compression

It is well known that the murine T helper cell clones are divided by their lymphokine secretory activities. One is the Th-1 cell, producing IL-2 and IFN after stimulation and the other is the Th-2 cell, producing the IL-4 and IL-5. This study was undertaken to evaluate the immunomodulatory properties of the bacterial lipopolysaccharide(LPS) on the lymphokine production in vivo and in vitro. The results were as follows: There were no effects on the lymphokine secretion by the in vitro treatment of the LPS. The in vivo treatment of the LPS decreases the capability of the production of IL-2 and IFN , whereas it increases the capability of IL-4 production. The altered capacity of the lymphokine production was recovered about 2 weeks after the treatment of the LPS. There were no differences on the lymphokine production between E-coli LPS and salmonella LPS. The capacity of the lymphokine production was the same in the treatment of a non-heated LPS or heated-LPS. The lymphokine production of the mice which were desensitized by the long term treatment of the LPS was not different from the control mice. The in vitro treatment of RU486 can block the alterations of the lymphokine production after the treatment of the LPS. In summary, one can tell that the LPS increases the secretion of the IL-4 through the endogenous secretion of the glucocorticoids.
Animals ; Clone Cells ; Glucocorticoids ; Interleukin-2 ; Interleukin-4 ; Interleukin-5 ; Mice ; Mifepristone ; Salmonella ; T-Lymphocytes* ; T-Lymphocytes, Helper-Inducer

The aim of our study is to achieve complete periodontal tissue regeneration by the application of BMP and resorbable membrane. Three beagle dogs aged over one and half years and weighed 14 to 16 kg were used in this study. Mandibular 1st, 2nd premolars were extracted bilaterally. Horizontal furcation defects were induced around 3rd, 4th premolars bilaterally. BMP-4 were applied in the right side with resorbable membranes and only resorbable membranes were applied in the left side respectively. Each animal was sacrificed at 2, 4, and 8weeks, after regenerative surgery. Specimens were prepared with Hematoxylin-Eosin stain and Goldner's modified Masson Trichrome stain for light microscopic evaluation. The results were as follows: 1. At 2 weeks after regenerative surgery, downgrowth of junctional epithelium was observed both in the membrane-applied site and BMP-4-and-membrane-applied site. 2. At 4 weeks after regenerative surgery, resorbable membranes were completely resolved, therefore would not prevent downgrowth of junctional epithelium. New bone formation, new cementum formation and Sharpey's fiber were observed in BMP-4-and-membrane-applied site. 3. At 8 weeks after regenerative surgery, downgrowth of junctional epithelium was observed in the membrane-applied site. But, new cementum formation was observed in the same site. The extensive regeneration of new bone, new cementum and remarkable formation of Shapey's fiber were showed in BMP-4-and-membrane-applied site. 4. Resorbable membranes were resolved via the cell-mediated processes. 5. Periodontal tissue regeneration were better achieved in the BMP-4-and-membrane-applied site than in the membrane-applied site. Within the above results, BMP-4 may have the strong capability to form the new bone and resorbable membrane may be able to prevent the bony ankylosis. However, resolution rate of resorbable membrane may not be enough to protect rapid epithelial downgrowth for ideal periodontal regeneration. In conclusion, I suggest BMP-4 may have the strong possibility to be utilized in the clinical periodontal treatments.
Animals ; Ankylosis ; Bicuspid ; Dental Cementum ; Dogs ; Epithelial Attachment ; Furcation Defects ; Membranes* ; Osteogenesis ; Regeneration*

The authors report 3 cases of intracranial cysticercosis simulating brain tumor. The 2 cases of them had parenchymatous huge cysts in the cerebral hemisphere and the other one had large cyst in the 4th ventricle. In one case of parenchymatous cysticercosis, angiographic finding was less significant though C-T scan revealed huge cystic shadow in the frontal lobe bilaterally and multiple small cystic shadow in occipital lobe and cerebellum. The 4th ventricular cysticercosis was well delineated with Conray ventriculography. All cases were proved as cerebral cysticercosis by operation and the patients were uneventful postoperatively.
Brain Neoplasms ; Cerebellum ; Cerebrum ; Cysticercosis* ; Frontal Lobe ; Humans ; Occipital Lobe

No abstract available.
Primary Myelofibrosis* ; Xanthogranuloma, Juvenile*