1.A clinical review of upper gastrointestinal bleeding.
Young Hwan CHO ; Joon Heon JEONG ; Il Dong CHUNG
Journal of the Korean Surgical Society 1991;41(2):159-167
No abstract available.
Hemorrhage*
2.A subclassification of conduct disorder by child behavior checklist.
Hwan Bae LEE ; Young Sook KWACK ; Ki Chung PAIK
Journal of Korean Neuropsychiatric Association 1992;31(2):351-362
No abstract available.
Checklist*
;
Child
;
Child Behavior*
;
Child*
;
Conduct Disorder*
;
Humans
4.Treatment of chronic isolated rupture of anterior cruciate ligament.
Hyun Kee CHUNG ; Do Gyoung LEE ; Young Hwan KIM
Journal of the Korean Knee Society 1993;5(1):55-61
No abstract available.
Anterior Cruciate Ligament*
;
Rupture*
5.Three Cases of Mirtazapine Induced Akathisia.
Seung Hwan LEE ; Min NAM ; Young Cho CHUNG
Journal of the Korean Society of Biological Psychiatry 2001;8(1):162-166
The mirtazapine is a relatively new antidepressant that has noradrenergic and specific serotonin antagonist action(NaSSAs). This has been known as one of the most safest drugs because of its few side effects. Until now, there have been only one case report that mirtazapine causes a EPS side effect(restless leg syndrome). But the peculiar mechanism of this drug makes it impossible to explain the exact reasons why the mirtazapine could induce EPS symptoms. Authors obseved three cases of mirtazapine indeced akathisia. We could not explain the phenomenon the other way except akathisia. So here we presents the three case of mirtazapine induced akathisia and a few possible hypothesis of this phenomenon.
Leg
;
Psychomotor Agitation*
;
Serotonin
6.Neurobiology of Alzheimer's Disease.
Young Cho CHUNG ; Seung Woo SEO ; Seung Hwan LEE
Journal of the Korean Society of Biological Psychiatry 2001;8(1):62-70
Alzheimer's disease(AD) is associated with a characteristic neuropathology. The major hallmarks of AD are senile plaques(SPs) and neurofibrillary tangles(NFTs). beta-amyloid protein(Abeta) is derived from the proteolysis of amyloid precursor protein(APP) and then converted to SPs. Mature SPs produce cytotoxicity through direct toxic effects and activation of microglia and complement. NFTs are composed of paired helical filaments(PHFs) including abnormally phosphorylated form of the microtubule-associated protein(MAP) tau and increased tau level in cerebrospinal fluid may be observed in most AD. The aggregation of Abeta and tau formation are thought to be a final common pathway of AD. Acetycholine, dopamine, serotonin, GABA and their receptors are associated with AD. Especially, decreased nicotinic acetylcholine receptors(nAChRs) in AD are reported. Genetic lesions associated with AD are mutations in the structural genes for the APP located on chromosome 21, presenilin(PSN)1 located on chromosome 14 and PSN2 located on chromosome 1. Also, trisomy 21, Apo-E gene located on chromosome 19, PMF locus, low density lipoprotein receptor-related protein and alpha-macroglobulin increase risk of AD. In this article, we will review about the neurobioloby of AD and some newly developed research areas.
Acetylcholine
;
Alzheimer Disease*
;
Amyloid
;
Amyloid beta-Peptides
;
Apolipoproteins E
;
Cerebrospinal Fluid
;
Chromosomes, Human, Pair 1
;
Chromosomes, Human, Pair 14
;
Chromosomes, Human, Pair 19
;
Chromosomes, Human, Pair 21
;
Complement System Proteins
;
Dopamine
;
Down Syndrome
;
gamma-Aminobutyric Acid
;
Genetics
;
Lipoproteins
;
Microglia
;
Neurobiology*
;
Proteolysis
;
Serotonin
7.A case report on human infection with Anisakis sp. in Korea.
Chong Hwan KIM ; Bong Seok CHUNG ; Young Il MOON ; Soong Hwan CHUN
The Korean Journal of Parasitology 1971;9(1):39-43
Authors experienced a case of human infection with Anisakis sp. in left tonsil. The case was 27 year Korean female who visited Department of Otolaryngology, Severance Hospital with the chief complaints of swollowing difficulty, and the sensation of a foreign body in the throat, on November 20th 1968. Physical examination of the oral cavity revealed that both palatin tonsil were chronically enlarged. A larval worm was found in crypt of the upper portion of the left palatin tonsil. Chief complaints of the patient was improved after removal of it by forceps. The greyish white living worm was fixed in lactophenol solution for morphological study. The worm measured 36 mm in length by 0.6 mm in width, 2.4 mm in esophageal length, 1.4 mm in ventricule, 0.1 mm in tail length, and 0.025 mm in caudal spine length, respectively and histological study was carried out from the serial section of the larva which was stained with hematoxylin eosin. Authors identified that the larva was Anisakis species.
parasitology-helminth-nematoda-Anisakis sp.
;
case report
;
tonsil
;
swollowing difficulty
8.Clinical anaysis of suction coagulator tonsillectomy.
Byoung Jun BAEK ; Ki Hwan KIM ; Seung Ju LEE ; Yoon Young CHUNG ; Cheon Hwan OH
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):193-198
No abstract available.
Suction*
;
Tonsillectomy*
9.Multiple ESWL treatment for renal stones with piezoelectric lithotriptor.
Young Tae MOON ; Chung Hwan OH ; Sae Chul KIM
Korean Journal of Urology 1991;32(6):941-949
From February 1987 to December 1990, 654 patients with renal stones completed the multiple ESWL monotherapies using the EDAP-LT01 piezoelectric lithotriptor. The location of stones was calyx in 452 patients. pelvis in 1O8. calyx and pelvis in 94 and the stone size ranged from 0.6 to 4.8cm (mean 1.9cm). The number of treatment sessions was 2 to 19 sessions (mean 4.7) with 72.2% of re-treatment rate. In accordance with increment of stone size, number of treatment increased but success rate decreased; 2.8 sessions. 96.2% for 0.6-<1 cm. 4.4, 93.2% for 1-<2 cm, 5.5. 87.7% for 2-<3 cm. 6.3, 65.5% for 3-<4 cm and 6.4, 58.8% for stones larger than 4 cm. Supposing 654 patients had been completed by 5 sessions only. 67.9% of success rate would have been expected. But. 88.4% (578,654) of success rate was obtained by multiple treatment up to 19 sessions, adding 20.5%. Auxiliary ureteral manipulations were required in 88 (13.5%) patients and there were no significant complications. Therefore. multiple ESWL monotherapy is considered to be a efficient. safe procedure as the first applicable method for treatment of larger renal stones and to extend the indications of ESWL for renal stone.
Humans
;
Pelvis
;
Ureter
10.Limb Salvage Surgery with Tumor Prosthesis for the Malignant Bone Tumors Involving the Proximal Femur.
Young Soo CHUN ; Jong Hun BAEK ; Seung Hyuk LEE ; Chung Hwan LEE ; Chung Soo HAN
The Journal of the Korean Bone and Joint Tumor Society 2014;20(1):7-13
PURPOSE: As well as patient survival, the restoration of postoperative function such as ambulation is important in limb salvage operations for treatment of malignant bone tumors involving the proximal femur. The authors analyzed clinical outcomes of limb salvage operations using tumor prostheses for metastatic or primary malignant bone tumors in the proximal femur. MATERIALS AND METHODS: From February 2005 to January 2014, 20 cases (19 patients) with malignant bone tumor involving the proximal femur with pain or complicated pathologic fracture were treated with segmental resection and limb salvage operations with tumor prostheses. Mean age was 63.1 years (range 35-86). Fourteen patients were male and six ones were female. The mean follow-up period was 20 months (1-94 months). There were 15 cases of metastatic bone tumor, 4 cases of osteosarcoma, and 1 case of multiple myeloma. The primary tumors of the metastatic bone tumors included 4 lung cancers, 3 hepatocellular carcinomas, and 3 renal cell carcinomas. Other primary tumors were breast cancer, thyroid cancer, colon cancer, prostate cancer, and malignant spindle cell tumor, each in 1 case. Modular tumor prostheses were used in all cases; (Kotz's(R) Modular Tumor prosthesis (Howmedica, Rutherford, New Jersey) in 3 cases, MUTARS(R) proximal femur system (Implantcast, Munster, Germany) in 17 cases). Perioperative pain was assessed with Visual Analogue Scales (VAS). Postoperative functional outcome was assessed with Musculoskeletal Tumor Society (MSTS) grading system. RESULTS: Out of 20 cases (19 patients), 11 cases (10 patients) survived at the last follow-up. Average postoperative survival of the 9 deceased patients was 10.1 months (1-38 months). VAS score improved from pre-operative average of 8.40 (5-10) to 1.35 (0-3) after operation. Average postoperative MSTS function score was 19.65 (65.50%, 7-28). The associated complications were 2 local recurrences, 3 hematomas, 3 infections, 2 scrotal swellings, and 1 dislocation. There was no case of periprosthetic fracture or loosening. CONCLUSION: Limb salvage operation with tumor prosthesis is an appropriate treatment for early pain reduction and functional restoration in malignant bone tumors in the proximal femur with pain an/or complicated pathologic fractures.
Breast Neoplasms
;
Carcinoma, Hepatocellular
;
Carcinoma, Renal Cell
;
Colonic Neoplasms
;
Dislocations
;
Female
;
Femur*
;
Follow-Up Studies
;
Fractures, Spontaneous
;
Hematoma
;
Humans
;
Limb Salvage*
;
Lung Neoplasms
;
Male
;
Multiple Myeloma
;
Osteosarcoma
;
Periprosthetic Fractures
;
Prostatic Neoplasms
;
Prostheses and Implants*
;
Recurrence
;
Thyroid Neoplasms
;
Walking
;
Weights and Measures