BACKGROUNDS: The high mortality and morbidity rates associated with traumatic rupture of the hollow viscera have been attributed to the clinical difficulty in establishing an early diagnosis. The accuracy of CT in the detection of injuries of the solid visceral organ is well established, but the value of CT in diagnosing small bowel perforation artier blunt abdominal trauma is controversal. This study was conducted to ascertain CT findings of small bowel perforation result from blunt abdominal trauma. METHODS: A retrospective analysis of preoperative abdominal CT findings in 40 patients was performed. Small bowel perforation was confirmed by surgery. Precontrast and postcontrast enhanced CT images were obtained in all patients. RESULTS: Diagnostic findings of small bowel perforation including intraperitoneal or retroperitoneal free air, discontinuity of the bowel wall and extravasation of oral or IV contrast materials were observed in 34 cases(85%). The most common fading of small bowel perforation was intraperitoneal or retroperitoneal free fluid collection(90%), followed by segmental bowel wall thickening(83%), intraperitoneal or retroperitoneal free air(80%) and focal mesenteric fat infiltration(70%). CONCLUSIONS : The CT scan is sensitive and effective modality for evaluation of small bowel perforation after blunt abdominal truauma, because of high detectability of diagnostic antral suggestive CT findings.
Contrast Media ; Diagnosis* ; Early Diagnosis ; Humans ; Mortality ; Retrospective Studies ; Rupture ; Tomography, X-Ray Computed ; Viscera

The extracellular cytolysin produced by V. ulnificus has gained great attention as a causative factor for the pathogenesis of V. vulnificus-infected disease. In this study, an attempt was made to elucidated the mechanism for the toxity of cytolysin. 1. Cytolysin given to mouse showed lethal activity with LD of 3.7 HU and produced hemoconcentration, suggesting that its lethal activitis attributable to the increased vascular permeability. 2. The lethal activity of cytolysin for mouse was prevented by intraperitoneal administration of clemastin or verapamil one hour before intravenous injection of cytolysin. 3. Treatment of peritoneal mast cells from rats with cytolysin stimulated histamine relesse irrespective of the prescence of extracellular Ca and the stimulatory effect of cytolysin was not affected by the pretreatment of mast cells with per tussis toxin. 4. The hemolytic activity and stimulatory effect of cytolysin on histamine release from mast cell were inhibited by cholesterol. The results suggest that the lethal activity of cytolysin is attributable to the increased vascular permeability which is resulted from the stimulation of histsmine release from mast cells and/or basophils by cytolysin.
Animals ; Basophils ; Capillary Permeability ; Cholesterol ; Histamine ; Histamine Release ; Injections, Intravenous ; Mast Cells ; Mice ; Perforin* ; Rats ; Verapamil ; Vibrio vulnificus* ; Vibrio*

Wilson's disease is an inborn error of copper metabolism which may be associated with hepatic cirrhosis and progressive degeneration of the central nervous system. The most common ophthalmologic finding in Wilson's disease is the Kayser-Fleischer ring. Other much less common physical signs include neurologic signs, endocrinologic abnormality. The Kayser-Fleischer ring occurs in the corneal periphery and is usually yellow- brown color. The Kayser-Fleischer ring.copper deposition at the level of the posteior position of Descemet's membran. The authours have recently experienced two cases of wilson's disease. One case. a 20-year-old girl, has Kayser-Fleischer rings in both eyes, amenorrhea, chronic active hepatitis and the other case, a 21-years-old girl, has dense yellow-green colored Kayser-Fleischer rings in both eyes, palilalia, and family relationship. Both cases have been treated with D-penicillaine and low copper diet. After treatment, clinical manifestation have been improved markedly at former case and the other cae is steady stage, but the Kayse-Fleischer rings have not disappeared yet in both cases.
Amenorrhea ; Central Nervous System ; Copper ; Diet ; Family Relations ; Female ; Hepatitis, Chronic ; Hepatolenticular Degeneration* ; Humans ; Liver Cirrhosis ; Metabolism ; Neurologic Manifestations ; Penicillamine ; Young Adult

Takayasu's arteritis is briefly as an inflammatory process of unknown etiology occuring dominantly in young female most commonly involving the great vessels arising from the aortic arch. The disease process results in stenosis and obliteration of involved vessels. Syncope in Takayasu's arteritis is known to result from decreased blood flow to brain because of stenosing blood vessels. We herein describe a case of paroxysmal atrioventricular block in a 40-year old man with Takayasu's arteritis. The patient presented with spontaneous recurrent syncope associated with paroxysmal AV block. Carotid sinus pressure repeatedly induced paroxysmal AV block and syncope. Carotid sinus pressure after pretreatment of atropine failed to induce AV block or syncope. Coronary angiogram was normal. We concluded that syncope in this patients was attributed to carotid hypersensitivity rather than decreased blood flow to the brain due to vessel stenosis.
Adult ; Aorta, Thoracic ; Atrioventricular Block* ; Atropine ; Blood Vessels ; Brain ; Carotid Sinus ; Constriction, Pathologic ; Female ; Humans ; Hypersensitivity ; Syncope ; Takayasu Arteritis*

Oro-facial dyskinesia (OFD) is involuntary, abnormal, uncontrolled and stereotyped movements, consisting of forehead furrowing, eye opening and closing, smacking and pursing of the lips, lateral deviation and protrusion of the tongue, and occasionally lateral deviation and protrusion of the jaw.1 OFD is known to have various complications including speech difficulty, chewing and eating disorders, and social embarrassment; facial muscle stiffness, mucosal and gingival traumatic lesions. In addition, it may leads to cranio-mandibular joint (TMJ) complications in the presence of intense and prolonged abnormal movements, with pain and degeneration.1,2 There is no previous report of TMJ dislocation due to OFD. In this report, we describe a patient who developed bilateral anterior TMJ dislocation due to OFD which occurred following intra-cranial hemorrhage (ICH).
Movement Disorders ; Dyskinesias

Osteopetrosis is a rare familial disease, characterized roentgenographically by a marked increase in the radiodensity of bone and by abnormality in the shape of the long bone, especially the metaphysis. It was discovered fist by Albers-Schonberg in 1904 during an X-ray examination of a patient and is known as Albers-Schonberg disease, marble bone or osteosclerosis fragilis generalisata. We experienced a case of osteopetrosis in adult.
Adult ; Calcium Carbonate ; Humans ; Osteopetrosis

PURPOSE: To evaluate the diagnostic usefulness of ultrasound-guided cutting-needle biopsy(CNB) with an automated biopsy device in head and neck masses. MATERIALS AND METHODS: A series of 153 consecutive head and neck masses in 133 patients, biopsied with an 18G cutting-needle and automated biopsy device under ultrasound guidance, was analysed for diagnostic yield and complications. Fine-needle aspiration biopsy(FNAB) was also performed on 88 masses and compared with the findings of CNB. RESULTS: Diagnostic specimens were obtained in 135 (88.2 %) of 153 masses. Eighty-four (90.3 %) of 93 lymph node CNBs provided a diagnostic histological specimen. Tuberculous lymphadenitis or chronic reactive hyper-palsia was diagnosed by CNB in 22 cases, but only six case were diagnosed by FNAB. Ten metastatic lymph nodes and two malignant lymphomas diagnosed by CNB were concordant with the findings of FNAB ; the exception was one case in which metastasis involved lymph nodes. Twenty-seven (77%) of 35 CNBs of thyroid nodule provided a diagnostic specimen. Seven of 28 FNAB cases in which CNB failed to provide a diagnostic specimen, revealed two papillary cancers and three benign nodular lesions. Twenty-five CNBs of soft tissue and salivary gland tumors provided diagnostic specimens; the exception was one probable hemangioma (96 %). In six of 11 FNABs of soft tissue and salivary gland masses, a diagnostic specimen was not obtained. There were four cases of hematoma (2.6%) without clinical significance. CONCLUSION: CNB of head and neck masses using an automated biopsy device is a useful and safe method. In the case of thyroid masses, however, FNAB is more useful and safe than CNB.
Biopsy* ; Biopsy, Fine-Needle* ; Diagnosis* ; Head* ; Hemangioma ; Hematoma ; Humans ; Lymph Nodes ; Lymphoma ; Neck* ; Neoplasm Metastasis ; Salivary Glands ; Thyroid Gland ; Thyroid Nodule ; Tuberculosis, Lymph Node ; Ultrasonography

No abstract available.

Nifedipine is the Ca++ channel blocker, of which action mechanism is blocking the calcium influx through the smooth muscle of vessels. It is known that Nipine(R) improve the visual field by increasing blood supply to the optic nerve with dilatation of vessels in low tension glaucoma patient whose visual field loss is thought to be caused by the ischemic change of optic nerve. We have clinically evaluated the sensitivities of visual fields of 7 cases (11 eyes) of low tcnsion glaucoma, who were medicated with Nipinetension glaucoma patient whose visual field loss is thought to be caused by the ischemic change of optic nerve. We have clinically evaluated the sensitivities of visual fields of 7 cases (11 eyes) of low tcnsion glaucoma, who were medicated with Nipine(R), 1Omg Tid per os for more than 2 weeks. The visual fields were tested at least 3 times or more with Humphrey automatic perimetry (Allergan, Statpac) and were divided into 10 sectors according to the nerve fiber bundles. In each sector, we analyzed the change of light sensitivity and global index, then compared by Student Pared t-Test. After medication of Nipine(R), improvements of mean light sensitivity in total sectors were found in 7 eyes among the 11 eyes and also superonasal portion of their visual field was more recovered than the other portions and they showed the improvement of the mean deviation but it was not significant.
Calcium ; Dilatation ; Glaucoma ; Humans ; Low Tension Glaucoma* ; Muscle, Smooth ; Nerve Fibers ; Nifedipine* ; Optic Nerve ; Photophobia ; Visual Field Tests ; Visual Fields*

No abstract available.