1.MR Imaging of Posterior Cruciate Ligament Injury.
Kyung Hee LEE ; Young Ja CHO ; Yang Hee PARK ; Jee Yean LEE ; Keum Nahn JEE
Journal of the Korean Radiological Society 1994;31(5):961-964
PURPOSE: There is increasing awareness of the clinical importance of early detection and treatment of posterior cruciate ligament(PCL) injury. We evaluate the usefulness of Magnetic resonance(MR) imaging in the diagnosis of PCL injury. MATERIALS AND METHODS: We retrospectively analysed the MR images of 140 cases with clinically suspected knee injury. Arthroscopic or surgical correlation was available in 63 cases. We observed the finding and extent of PCL injury and other associated abnormalities. The frequency of anterior and posterior meniscofemoral ligament was evaluated. RESULTS: Eleven PCL injuries were observed, six midsubstance tears, two tibial attachment tears, two fernoral attachment tear, one laxity. The sensitivity, specificity and accuracy of MR imaging diagnosis are 100%, 98.1%, 98.4%. MR findings of PCL injury are discontinuity and focal mass formation, irregular increased signal intensity, detachment or redundancy of the ligament with avulsed bony fragment. In all cases of injured PCL, other associated abnormalities of adjacent structures were observed. Accessory anterior and posterior meniscofemoral ligaments were observed in 67.4%(87/129). CONCLUSION: MR imaging is useful in evaluation of presence or absence of PCL injury, accurate extent of PCL injury and other important associated abnormalities of adjacent structures.
Diagnosis
;
Knee Injuries
;
Ligaments
;
Magnetic Resonance Imaging*
;
Posterior Cruciate Ligament*
;
Retrospective Studies
;
Sensitivity and Specificity
2.Microcystic Adnexal Carcinoma: Report of a case.
Eun Deok CHANG ; Young Hee JEE ; Sun Moo KIM
Korean Journal of Pathology 1993;27(3):290-292
Microcystic adenxal carcinoma is an unusual, locally aggressive neoplasm that has recently been recongized as a clincopathologic entity. Its histologic appearance includes both pilar and eccrine differentiation. Microscopically, the tumor consisted of small cysts and gland-like structures in superficial portion. In other area, basaloid cell nests and abortive hair follicles in the sclerotic stroma were seen. The cysts were filled with secretory eosinophilic material, which was positively stained with Periodic acid-Schiff and carcinoembryonic antigen. Immuno-peroxidase staining for carcinoembryonic antigen supported the dual differnetiation of this neoplasm. Despite the benign histologic appearance, there was deep and extensive infiltration of the subcutaneous tissue.
Cysts
3.Anticancer Effect and Apoptosis of All-trans-retinoic Acid on the Human Ovarian Epithelial Carcinoma Cell Lines.
Jee Young HAN ; Woo Hee JUNG ; Tai Seung KIM
Korean Journal of Pathology 2000;34(3):225-234
Ovarian carcinoma is a serious disease in women. Some reports revealed all-trans-retinoic acid (tRA) inhibited the proliferation of ovarian carcinoma cell lines and induced apoptosis. The aim of this study was to evaluate the anticancer and apoptotic effects of tRA and the expression of the retinoic acid receptor (RAR) alpha, beta, gamma, p53, bcl-2, and c-myc genes on the ovarian carcinoma cell lines, NIH OVCAR3 and SKOV3. In both cell lines, the proliferation of tumor cells was inhibited and characteristic morphologic patterns of apoptosis were shown after treatment of tRA. The number of apoptotic cells and the percentage of apoptosis were increased after treatment of tRA. The gel electrophoresis revealed the DNA ladder pattern in the NIH OVCAR3. Gene expressions were observed using northern blotting. There was no RARalpha expression in both cell lines. In NIH OVCAR3, there was no changes in the expression of RARbeta and bcl-2 gene. The RARgamma gene expression of tRA treated group was slightly increased, but p53 gene expression was decreased, and c-myc gene was not expressed. In SKOV3, the expressions of RARbeta, gamma, and p53 genes were increased and that of bcl-2 was decreased in the tRA treated group. There was no change in c-myc gene expression. These results suggest tRA has anticancer and apoptotic effect on both ovarian carcinoma cell lines. RARbeta, RARgamma, bcl-2, and p53 gene expressions were correlated with these effects of tRA on SKOV3 but not on NIH OVCAR3.
Apoptosis*
;
Blotting, Northern
;
Cell Line*
;
DNA
;
Electrophoresis
;
Female
;
Gene Expression
;
Genes, bcl-2
;
Genes, myc
;
Genes, p53
;
Humans*
;
Receptors, Retinoic Acid
;
Tretinoin*
4.Treatment of Chronic Cough in Primary Care.
Journal of the Korean Academy of Family Medicine 2004;25(6):441-446
No abstract available.
Cough*
;
Primary Health Care*
5.Malignant Mixed Mullerian Tumor of the Fallopian Tube: Report of a Case.
Eun Deok CHANG ; Young Hee JEE ; Sun Moo KIM
Korean Journal of Pathology 1988;22(1):92-96
Malignant mixed mullerian tumor of the fallopian tube is an extremely rare neoplasm. To date, only 26 cases of primary malignant mixed mullerian tumor of the fallopian tube have been reported, and no report has been published in Korea. This is not surprising, since as a group these meoplasms are least likely to occur in the fallopian tube; the most common sites being the endometrium, vagina, cervix and ovary. We report a case of malignant mixed mullerian tumor of the fallopian tube ina 63-year-old woman with brief review of the literatures.
Female
;
Humans
6.Adenoid Cystic Carcinoma of Skin: A case report.
Eun Duk CHANG ; Young Hee JEE ; Sun Moo KIM
Korean Journal of Pathology 1989;23(3):378-381
A primary skin adenoid cystic carcinoma first described by Boggio in 1975, is one of the rarest type of eccrine sweat gland carcinoma. Histologically, a tumor with typical morphologic features closely resembles adenoid cystic carcinoma was found in other tissues but in the skin must be distinguished from aggressive basal cell carcinoma. The natural history of this tumor is not yet fully determined but suggests a long indolent and progressive course. We report a case of a 77-year-old male with a small skin nodule in the abdomen.
Male
;
Humans
7.Malignant Acanthosis Nigricans Associated with Stomach Adenocarcinoma.
Young Hee JEE ; Eun Joo SEO ; Mi Kyung HUR ; Chin Hee CHO ; Sun Moo KIM
Korean Journal of Pathology 1985;19(1):88-91
Malignant acanthosis nigricans is very rare disease. The disease is related with internal malignancy, especially gastrointestinal tract malignancy. Reported occurrence rate of malignant acanthosis nigricans associated internal malignancies are 64% of stomach adenocarcinoma, 27% of other organs of abdomen (liver, gall bladder, small intestine, rectum, uterus, ovary), 9% of non-abdominal organs(breast, lung). We report a case of malignant acanthosis nigricans associated with stomach adenocarcinoma from 20-year-old female and discuss review of literature on a acanthosis nigricans briefly.
Female
;
Humans
;
Adenocarcinoma
8.Congenital Mesoblastic Nephromas with lmmunohistochemical and Flow Cytometric Analysis.
Woo Hee JUNG ; Yee Jeong KIM ; Jee Young HAN ; Woo Ick YANG ; Dae Young KANG
Korean Journal of Pathology 1995;29(3):303-310
We reviewed 7 cases of congenital mesoblastic nephroma (4 cases of classical mesoblastic nephroma (CMN) and 3 cases of atypical mesoblastic nephroma (AMN)) using immuno-histochemical and flow cytometric study. Results are as follows. 1) The mean tumor size was 5 (3 to 7cm)cm in CMN and 9 (7 to 10cm)cm in AMN. The AMN revealed hemorrhage and necrosis in two Of three cases. A case of AMN showed cystic change without hemorrhage and necrosis. Mitotic count ranged in 0~4/10HPF in CMN and 20-35/10HPF in AMN. 2) Immunohistochemistry for vimentin was all positive. Actin, desmin were weakly positive in CMN, but negative in AMN. The findings were consistent with myofibroblastic differentiation in CMN and AMN was considered to be the less differentiated form of CMN. 3) Flow cytometiic analysis showed diploidy in two of two CMNs and two of three AMNs. Only one AMN showed aneuploidy with DNA index of 1.41. %SG2M were 8.1 and 15.9 (mean 12.0) in CMN and 16.9, 32.9 and 19.3 (mean 22.9) in AMN, respectively. We concluded that AMN should be distinguished from CMN, clinicopathologically.
9.Clock drawing test to screen for dementia in parkinsonian patients with low educational backgrounds
Han-Yeong Jeong ; Jee-Young Lee ; Hee Kyung Park ; Sohee Oh ; Jun-Young Lee
Neurology Asia 2016;21(4):357-365
Objectives: This study was aimed to assess the usefulness of the quantitative assessment of clock
drawing test (CDT) combined with the Mini-Mental State Examination (MMSE) compared to that
of the Montreal Cognitive Assessment (MoCA) or the MMSE alone for screening of dementia in
Parkinson disease (PD) in patients with a low educational level. Methods: A representative sample of
91 PD patients was administered MMSE, MoCA and CDT. The discriminative validity of the MMSE,
MoCA, and a MMSE+CDT combination for dementia screening was determined by estimating the
sensitivity and specificity of each test and by testing integrated discrimination improvement (IDI).
Results: The mean age and educational years were 69.0 (years) and 7.3 in the study population. The
best screening cut-off points for the MMSE, MoCA, and MMSE+CDT were 25/26, 21/22 and 41/42.
In a group of patients with educational years ≤6,
Dementia
10.A Case of Relapsed Lepromatous Leprosy Misdiagnosed as Granuloma Faciale.
Yong Se CHO ; Jee Hee SON ; Yunsun BYUN ; Bo Young CHUNG ; Hyeone KIM ; Chun Wook PARK
Korean Journal of Dermatology 2017;55(3):215-217
No abstract available.
Granuloma*
;
Leprosy, Lepromatous*