A 35 year old woman, gravid 5, multiparous, was admitted to our department at 6 weeks and 5 days of gestation after being diagnosed with cervical pregnancy. Before the evacuation, the uterine arteries were embolized using angiographic techniques. As a result, dilatation and curettage were performed with minimal hemorrhage. We report one case of cervical pregnancy managed, successfully with preoperative uterine artery embolization and evacuation.
Adult ; Dilatation and Curettage ; Female ; Hemorrhage ; Humans ; Pregnancy* ; Uterine Artery Embolization* ; Uterine Artery*

No abstract available.
Diverticulum*

The congenital cataracts are lens opacity which are present at birth or within 3 months after birth. The pathogenesis of congenital cataract is no less varied and complex than that of adult-onset or senile lens opacification, but most of etiology is unknown. Inheritance can play a major role in their etiology and the most mode of inheritance is autosomal dominant. However, the possibility of preventing the disease in future generation through genetic counseling give the ophthalmologist responsibility in the recognition and classification of congenital lens opacities. We experienced hereditary congenital cataract, and so we reported these patients with review of literatures.
Cataract* ; Classification ; Genetic Counseling ; Humans ; Parturition ; Social Responsibility ; Wills

BACKGROUND: The erythromycin-resistance rate and phenotype distribution of Streptococcus propenes are quite different by geographical variation and study period. The aim of the present study was to determine the evolution of resistance to erythromycin and the frequency of erythromycin resistance phenotype of S. pyogenes isolated from Wonju Christian Hospital. METHODS: The minimal inhibitory concentrations (MICs) of erythromycin and clindamycin for 94 S. pyogenes isolated from clinical specimens between 1990 to 1998 were investigated. Double disk test of erythromycin (78microgram) and clindamycin (25microgram) were performed for 15 isolates of erythromycin resistant S. pyogenes to evaluate the erythromycin resistance phenotype. RESULTS: The resistance rates of 94 isolates of S. pyogenes were 16%(15/94) to erythromycin and 4%(4/94) to clindamycin. The frequency of erythromycin resistance phenotype in decreasing order were M phenotype (47%), inducible resistance phenotype (40%), and constitutive resistance phenotype (13%). Erythromycin-resistant S. pyogenes did not exist until 1993, but was isolated since 1994, and ranged from 14.0% to 24.0% during the period of 1994-1998. CONCLUSIONS: Our finding documents the emergence of high resistance rates to erythromycin in S. pyogenes at Wonju area since 1994. The M phenotype (47%) and inducible resistance phenotype (40%) account for the majority of erythromycin-resistant S. pyogenes.
Clindamycin ; Erythromycin* ; Gangwon-do ; Phenotype* ; Streptococcus pyogenes* ; Streptococcus*

BACKGROUND: Herpes simplex virus thymidine kinase (HSVtk) phosphorylates the prodrug ganciclovir to a nucleoside analog that inhibits DNA synthesis, causing cell death. Neighbouring nontransfected cells may be affected through a 'bystander effect', thereby amplifying the antiproliferative actions. This study was carried out to determine whether retrovirus-mediated HSVtk gene therapy could reduce intimal hyperplasia and prevent stenosis following balloon injury of the rat carotid artery. METHODS: A replication-defective recombinant retroviral vector containing HSVtk cDNA (LtkSN) was constructed. Cultured primary rat smooth muscle cells (SMCs) infected with this vector (SMC/LtkSN) were transplanted to the balloon injured rat right carotid artery. One week after transplantation, HSVtk gene therapy group was administered a 2-week treatment of ganciclovir (30 mg/kg/d). Three weeks after balloon injury and SMC/LtkSN transplantation, carotid arteriography was performed and carotid arteries were perfusion-fixed for histologic examination. RESULTS: Carotid arteriographic evaluation comparing with the uninjured left carotid artery showed that the mean luminal diameter of HSVtk gene therapy group (n=5, 85+/-3%) was significantly larger than that of balloon injury only group (n=5, 65+/-5%). The neointimal mass of HSVtk gene therapy group was less than that of balloon injury only group. SMC/LtkSN transplantation without ganciclovir treatment group (n=3) showed asymmetric intimal proliferation probably because of gravitational pooling of seeding. There were inflammatory cell infiltrations at the gravity dependent portion of HSVtk gene therapy group. CONCLUSION: Retrovirus-mediated HSVtk gene therapy following balloon injury of the rat carotid artery reduced neointimal expansion and arteriographic stenosis.
Angiography ; Animals ; Carotid Arteries* ; Carotid Artery Injuries* ; Cell Death ; Constriction, Pathologic* ; DNA ; DNA, Complementary ; Ganciclovir ; Genetic Therapy* ; Gravitation ; Herpes Simplex* ; Hyperplasia ; Myocytes, Smooth Muscle ; Phenobarbital ; Phosphotransferases* ; Rats* ; Simplexvirus* ; Thymidine Kinase ; Zidovudine

No abstract available.
Delivery of Health Care* ; Family Practice* ; Humans ; Inpatients* ; Insurance* ; Korea*

No abstract available.
Congenital Hypothyroidism*

The orbital varices are rare venous malformation of the orbit. These lesions typically present in childhood or adolescence with mild to moderate proptosis that increase on crying, coughing, jugular vein compression, and Vasalva's maneuver. Barely, orbital varices are associated with venous malformations outside the orbit: the buccal mucosa(the uvula, the soft palate, and the hard palate), in the upper and lower limbs, in the side of the neck, and in the face and head. Diagnosis is made by clinical findings, simple skull X-ray, and orbital venography. Recently, orbital C-T scanning gives some beneficials in diagnosis for orbital varices. The authors experienced a case of the orbital varix with varix in the buccal mucosa. So, the brief literature of the orbital varix was reviewed.
Adolescent ; Cough ; Crying ; Diagnosis ; Exophthalmos ; Head ; Humans ; Jugular Veins ; Lower Extremity ; Mouth Mucosa* ; Neck ; Orbit* ; Palate, Soft ; Phlebography ; Skull ; Uvula ; Varicose Veins*

The orbital varices are rare venous malformation of the orbit. These lesions typically present in childhood or adolescence with mild to moderate proptosis that increase on crying, coughing, jugular vein compression, and Vasalva's maneuver. Barely, orbital varices are associated with venous malformations outside the orbit: the buccal mucosa(the uvula, the soft palate, and the hard palate), in the upper and lower limbs, in the side of the neck, and in the face and head. Diagnosis is made by clinical findings, simple skull X-ray, and orbital venography. Recently, orbital C-T scanning gives some beneficials in diagnosis for orbital varices. The authors experienced a case of the orbital varix with varix in the buccal mucosa. So, the brief literature of the orbital varix was reviewed.
Adolescent ; Cough ; Crying ; Diagnosis ; Exophthalmos ; Head ; Humans ; Jugular Veins ; Lower Extremity ; Mouth Mucosa* ; Neck ; Orbit* ; Palate, Soft ; Phlebography ; Skull ; Uvula ; Varicose Veins*

PURPOSE: The residual intrahepatic stones with biliary strictures are difficult to remove percutaneously via T-tube tract after surgery in patients with recurrent pyogenic cholangitis. We evaluated the effectiveness of percutaneous balloon dilatation of benign biliary strictures. MATERIALS AND METHODS: The balloon dilatations with 6-12mm angioplasty balloon catheter and stone extractions were performed via a T-tube tract after surgical treatment in 15 patients with recurrent pyogenic cholangitis. The balloons were inflated for 3-4minutes under 5 atm. until disappearance of waist of the stricture site, from one to seven session. After balloon dilatation, residual stones were extracted with saline irrigation or stone basket. RESULTS: Among total 42 strictures, the balloon dilatation was succesful in 27 strictures(64.3%), partially successful in 12 strictures(28.6%), and failed in three strictures(7.1%). Single or central biliary strictures were dilated easily rather than multiple ductal strictures. Of 26 sites with residual intrahepatic stones, stone extraction was complete in 17 sites(65.4%), incomplete in seven sites(26.9%) due to impacted or large stone and acute ductal angulation, and failed in two sites(7.7%). CONCLUSION: Percutaneous balloon dilatation of benign biliary strictures is an effective procedure for extraction of residual intrahepatic stones associated with recurrent pyogenic cholangitis.
Angioplasty ; Catheters ; Cholangitis ; Constriction, Pathologic* ; Dilatation* ; Humans