1.A study on the effect of PDGF(platelet-derived growth factor) on wound healing.
Ji Young SONG ; Sung Pyo HONG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(5):802-812
No abstract available.
Wound Healing*
;
Wounds and Injuries*
2.Mercury contents in scalp hair of dentists and in their dental office.
Kyung Hee SONG ; Doo Hie KIM ; Jong Young LEE
Korean Journal of Occupational and Environmental Medicine 1991;3(1):21-31
No abstract available.
Dental Offices*
;
Dentists*
;
Hair*
;
Humans
;
Scalp*
3.Post-Laminectomy Swan Neck Deformity in Adults
Myung Sang MOON ; Kee Yong HA ; Young Kyun WOO ; Doo Hoon SUN ; Young Oh SONG
The Journal of the Korean Orthopaedic Association 1994;29(6):1536-1541
Five adult cases of post-laminectomy swan-neck deformity are reported. The factors causing the deformity, prophylactic measures, and treatment of the deformity are discussed. It is strongly adviced to the neurosurgeons and orthopedic surgeons that they should be aware of this unwanted complication of the multi-level cervical laminectomies, and that they should provide every preventive measures before post-laminectomy swan neck deformity develops. Anterior interbody fusion spanning the entire unstable segments is preferably recommended together with application of pre-fusion traction.
Adult
;
Congenital Abnormalities
;
Humans
;
Laminectomy
;
Neck
;
Neurosurgeons
;
Orthopedics
;
Surgeons
;
Traction
4.Clinical Analysis of 200 Renal Transplantations.
Kyeng Ha RYU ; Young Saeng KIM ; Seong Doo CHO ; Nam Weon SONG
Korean Journal of Anesthesiology 1997;33(5):944-952
BACKGROUND: Since the initial report on anesthesia for the renal transplantation from Peter Bent Brighan Hospital in 1962, the anesthesia for kidney transplantation has been reviewed and discussed by many authors. We have performed 200 renal transplantations from August 1990 to October 1996. No cadaveric donor was used and all except two cases was the first graft. METHODS: Anesthetic procedures in the recipients were as follows; 1) The recipient was dialysed within 24 hrs prior to operation. 2) Premedication was done as glycopyrrolate and fentanyl, or glycopyrrolate and diazepam. 3) Thiopental and vecuronium, or thiopental and succinylcholine were used for anesthetic induction. 4) N2O-O2-relaxant (vecuronium) with halothane or isoflurane were used for maintenance. 5) Neostigmine or pyridostigmine were also used to antagonize against the relaxant. 6) CVP was maintained around 10~17 cmH2O. RESULTS: The results were as follows; 1) The mean ages of donors and recipients were 35.3 and 37.4, respectively. The ratio of male to female of donors and recipients was 1.6 : 1 and 1.6 : 1, respectively. 2) One hundred and ten cases (55.0%) were living unrelated donors and 90 cases (45.0%) were living related donors. 3) Overall graft and patient survival rate was 96.9 and 98.0 at 1 year, 94.1 and 95.1 at 3 years. CONCLUSIONS: Most patients with renal failure have several common problems that are of significance to anesthesiologists, including anemia, bleeding tendency, electrolyte imbalance, acidosis, hypertension, hyper- or hypovolemia, and previous therapy with steroids and immunosuppressants, etc. Therefore anesthesiologists should keep in mind the risk factors above mentioned for the anesthetic management of patients with renal failure.
Acidosis
;
Anemia
;
Anesthesia
;
Cadaver
;
Diazepam
;
Female
;
Fentanyl
;
Glycopyrrolate
;
Halothane
;
Hemorrhage
;
Humans
;
Hypertension
;
Hypovolemia
;
Immunosuppressive Agents
;
Isoflurane
;
Kidney Transplantation*
;
Male
;
Neostigmine
;
Premedication
;
Pyridostigmine Bromide
;
Renal Insufficiency
;
Risk Factors
;
Steroids
;
Succinylcholine
;
Survival Rate
;
Thiopental
;
Tissue Donors
;
Transplants
;
Unrelated Donors
;
Vecuronium Bromide
5.Effect of alpha-Interferon 2b on Chronic Hepatitis B Patients with High Serum ALT.
Yeungnam University Journal of Medicine 1998;15(2):237-245
No abstract available.
Chronic Disease
;
Hepatitis B
;
Hepatitis B, Chronic*
;
Hepatitis, Chronic*
;
Interferon-alpha*
6.Molecular Epidemiological Characteristics of Vibrio parahaemolyticus Isolated from Diarrheal Patients in Jeonnam, Korea.
Doo Young JEON ; Jeong Chi LEE ; Hyeon Je SONG
Journal of Bacteriology and Virology 2009;39(3):229-235
To investigate the occurrence and distribution of serotype, specific virulence genes, and pulse field gel electrophoresis (PFGE) patterns in Vibrio parahaemolyticus isolates from Jeonnam, Korea, we tested 87 strains which were identified with V. parahaemolyticus from diarrheal episode patients in 2005. In this study, 16 different O:K serotype combinations of V. parahaemolyticus were determined. The distributions of O and K serotypes were O4:K68 (51.72%), O1:K70 (18.39%), O3:K6 (5.74%), O1:K68 (4.60%) and O3:K57 (4.60%) respectively. Serotype O4:K68 was the regional dominant specific serotype of V. parahaemolyticus in Sinan of Jeonnam, Korea. For the detection of thermostable direct hemolysin (tdh) and TDH-related hemolysin (trh) gene of V. parahaemolyticus, PCR was performed. The tdh gene was detected in all of the V. parahaemolyticus isolates from diarrheal patients, but trh gene was not detected. Analysis of PFGE patterns of 30 V. parahaemolyticus isolates showed 3 groups and 20 types. Among 14 O4:K68 serotypes which were isolated in Sinan, PFGE patterns of 12 strains were closely related (100%), but 2 strains were related by 58.3% and 45.4%, respectively. Also two strains of O1:K4 serotype in Gurye and two strains of O3:K6 serotype in Yeosu were closely related (100%), respectively. Although serotypes (O1:K4, O1:K70, O3:K6 and O4:K68) were different, PFGE patterns were related for more than 80.9%. Therefore, the epidemiological surveillance of V. parahaemolyticus is required by PFGE typing scheme as a further diagnostic tool.
Bacterial Toxins
;
Electrophoresis
;
Hemolysin Proteins
;
Humans
;
Korea
;
Polymerase Chain Reaction
;
Serotyping
;
Vibrio
;
Vibrio parahaemolyticus
7.Patella Chondromalacia
Kyung Doo LEE ; Kyung Song PARK ; Min LEE ; Young Girl LEE
The Journal of the Korean Orthopaedic Association 1984;19(2):311-316
Early chondromalacia patellae is initiated by malalignment in the extensor machaniam and abno-rmal patellofemoral tracking. It is well known that chondromalacia often occurs in recurrent pateIlar subluxation. In the 50 normal and 60 pathologic knees, the following five parameters were studied; 1) Q angle 2) PT ratio by Insall & Salvati method 3) AB ratio dy Blackburne & Peel method 4) sulcus angle 5) congruence angle. The following conclusions were made. l. In 50 normal asymptomatic knees, the average Q angle was 14°. The patellar length was equal to the patellar ligament length and the average congruence angle was −8°. In 40 knees with “Chondromalacia”, the Q angle was increaed (19.5°), and the average congruence angle was −2°. 3. In 20 knees with recurrent subaxation, the patellar was high riding (PT ratio, 0.89), the sulcus angle was shallow (145.1°), and the average congruence angle was +4.35°.
Cartilage Diseases
;
Chondromalacia Patellae
;
Knee
;
Methods
;
Patella
;
Patellar Ligament
8.Retrograde Tracheal Intubation through Cricothyroid Membrane and Cricotracheal Ligament.
Sang Min YUN ; Young Saeng KIM ; Seong Doo CHO ; Nam Weon SONG
Korean Journal of Anesthesiology 1995;29(2):304-309
Numerous devices and techniques have been devised to facillitate the difficult endotracheal intubation. Percutaneous retrograde intubation was first described by Waters, who used a Tuohy needle to puncture the cricothyroid membrane and an epidural catheter as a guideline in 1963 and many variations on the technique have been described. Failure to intubate 2 male adult patients were planned retrograde tracheal intubation using the cricothyroid membrane. While the patients were awake, and after adequate local anesthesia was obtained, a 16G Medicut was punctured through cricothyroid membrane. After confirmation of the intratracheal position by aspiration of air into syringe, the opening of the Medicut was directed upward foward the larynx and the epidural catheter was inserted through it and advanced retrograde between the vocal cords and into mouth. The epidural catheter tip was passed through the Murphy's eye from outside to inside and out of the tracheal tube. By keeping the catheter taut and coincidently pulling back, the tube was advanced into trachea. Correct positioning of the tracheal tube inside the trachea was confirmed by end-tidal carbon dioxide monitoring and auscultation. Another 2 male adult patients were intubated by using cricotracheal retrograde approach method. We experienced successful retrograde tracheal intubation without significant complications using an epidural catheter through cricothyroid membrane and cricotracheal ligament in 4 male adult patients who were predicted impossibility of simple orotracheal intubation. (Korean J Anesthesiol 1995; 29: 304~309)
Adult
;
Anesthesia, Local
;
Auscultation
;
Carbon Dioxide
;
Catheters
;
Humans
;
Intubation*
;
Intubation, Intratracheal
;
Larynx
;
Ligaments*
;
Male
;
Membranes*
;
Mouth
;
Needles
;
Punctures
;
Syringes
;
Trachea
;
Vocal Cords
9.The Incidence of Hypoxia Following the Use of Hypnotics and Analgesics during Spinal Anesthesia.
Myung Hwa HA ; In Cheol CHOI ; Young Saeng KIM ; Seong Doo CHO ; Nam Won SONG
Korean Journal of Anesthesiology 2000;39(6):792-797
BACKGROUND: The purpose of this study was to find out the effect of hypnotics and analgesics on oxygen saturation by pulse oximetry in surgery patients under spinal anesthesia. METHODS: Sixty-five patients classified ASA physical status 1 or 2 scheduled for surgery under spinal anesthesia were studied. These patients were divided into three groups. The 22 subjects of the first group did not receive either midazolam or fentanyl. The 22 subjects of the second group received midazolam. The 21 subjects of the third group received midazolam (0.03 mg/kg) and fentanyl (1.0 microgram/ kg). Oxygen saturation was measured with a pulse oximetry. Measurements were made before spinal anesthesia, 5 minutes, and 10 minutes after starting of spinal anesthesia, 5 minutes, 10 minutes, 30 minutes, and 60 minutes after the start of the operation or intravenous injection of drugs. In addition, measurements were made on arrival in the recovery room, and 5 minutes, 10 minutes, 20 minutes, and 30 minutes after arrival in the recovery room. RESULTS: There were statistically significant differences in oxygen saturation at 5 minutes after the start of the operation or intravenous injection of drugs. The mean oxygen saturation for the first group was 98.2 +/- 1.8%, for the second group 97.9 +/- 2.6%, and for the third group 92.4 +/- 2.8%. Hypoxia cases at 5 minutes after the start of the operation or intravenous injection of a drug occurred in 4.5% of the first group, 9.1% of the second group, and 57.1% of the third group CONCLUSIONS: We concluded that oxygen saturation monitoring should be done routinely in patients receiving hypnotics and analgesics during spinal anesthesia, and oxygen should be administered to patients who develope hypoxia during spinal anesthesia.
Analgesics*
;
Anesthesia, Spinal*
;
Anoxia*
;
Fentanyl
;
Humans
;
Hypnotics and Sedatives*
;
Incidence*
;
Injections, Intravenous
;
Midazolam
;
Oximetry
;
Oxygen
;
Recovery Room
10.Immediate and Late Results of Percutaneous Mitral Balloon Valvuloplasty Using Inoue and Double Balloon Techniques(Prospective Randomized Trial): Comparison of Mechanism of Dilation and 1 Year Follow-up.
Seung Jung PARK ; Jae Joong KIM ; Seong Wook PARK ; Jae Kwan SONG ; Young Cheoul DOO ; Simon Jong LEE
Korean Circulation Journal 1992;22(5):754-767
BACKGROUND: Large series of patients with symptomatic mitral stenosis have undergone percutaneous mitral balloon valvuloplasty(PMV) with use of the Inoue or double balloon technique. But to date the result of the two procedure have not been compared with a single series prospectively. METHODS: In order to assess the immediate hemodynamic results and the longterm efficacy of two different PMV technique, a prospective, randomized trial of PMV was performed using the Inoue balloon(Toray, I group) in 59 patients and the double balloons(a pair of Mansfield balloon. D group) in 61 patients with moderate to severe mitral stenosis. Before valvuloplasty, the patients series were comparable with regard to average age. gender, most clinical and echocardiographic variables. All the patients(120 patients, M/F 38/82, mean age 41+/-11 year) were preselected with good echoscore> or =9. RESULTS: The success rate was 83% in the I group and 89% in the D group when the success defined as mitral valve area(MVA)> or =1.5cm2 with 25% gain in MVA and mitral regurgitation> or =2+ at the end of procedure. The magnitude of increase of mitral valve area and decrease of mitral gradient, left atrial pressure and pulmonary arterial pressure were not significantly different in the Inoue and double balloon series(1.0+/-0.4 and 1.1+/-0.4cm2 for mitral vale area, 10.2+/-6.6 and 11.7+/-6.4mmHg for mitral gradient, 10.5+/-6,4 and 12.9 +/-7,3mmHg for left atrial pressure, and 8.7+/-7.3 and 10.1+/-9.4 mmHg for pulmonary artrial pressure respectively). Immediatly after dilation, the long diameter changes of the mitral orifice was more prominent in the D group(from 1.0+/-0.2 to 2.6+/-0.4cm p<0.01) than those in I series(from 1.1+/-0.4 to 2.3+/-0.3cm) Moreover, the magnitude of increase in the EF slop was significantly larger in the D group(31.9+/-17.0 vs 21.8+/-14.2mm/sec, p<0.001). The duration of total procedure(56+/-20 vs 84+/-24 min, p<0.002) and the fluoroscopic time (15+/-6 vs 25+/-11min, p<0.002) was significantly shorter in group I. The incidence of left to right shunt at the atrial level(Qp/Qs>1.5) was 3.4% in group I and 4.9% in group D. Severe mitral regurgitation> or =3+ occurred in 2 patients in each I(3.4%) and D(3.3%) group respectively. At follow-up, the mitral valve area was significantly decreased(1.6 in group I vs 1.8cm2 in group D, P<0.001 vs immediate after MVA) at 6 months and well maintained at 1 year follow-up in both groups. Until 6 months after valvuloplasty, the long diameter of orifice was greater in group D, however the difference was not apparent at 1 year follow-up. CONCLUSION: The Inoue and double balloon techniques obtained equivalent results of the success rate and the frequently of complications. However, the Inoue balloon technique reduced significantly fluoroscope time and total procedure duration. Double balloon technique afforded a longer longitudinal splitting of the commissure immediatly and 6 months after valvuloplasty. However the differences was not apparent at 1 year follow-up. Increased MVA was well maintained at 1 year in both groups. The severity of the newly developed mitral regurgitation immediately after valvuloplasty reduced significantly in 53% of the Inoue and 43% in the double balloon group at 6 months follow-up. In the view point of similiar immediate and late results of the two methods, the stepwise dilation with Doppler echocardiographic monitoring during the Inoue procedure appeared to be cumbersome.
Arterial Pressure
;
Atrial Pressure
;
Balloon Valvuloplasty*
;
Echocardiography
;
Follow-Up Studies*
;
Hemodynamics
;
Humans
;
Incidence
;
Mitral Valve
;
Mitral Valve Insufficiency
;
Mitral Valve Stenosis
;
Prospective Studies