2.Prevalence and Clinical Features of Probable REM Sleep Behavior Disorder- An Epidemiological Study in Osan City.
Young Min CHOE ; In Young YOON ; Ki Woong KIM ; Sang Don LEE ; Gawon JU ; Joon Hyuk PARK
Sleep Medicine and Psychophysiology 2011;18(1):23-28
OBJECTIVES: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. METHODS: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. RESULTS: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. CONCLUSIONS: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.
Aged
;
Depression
;
Epidemiologic Studies
;
Humans
;
Mass Screening
;
Prevalence
;
Surveys and Questionnaires
;
REM Sleep Behavior Disorder
;
Sleep, REM
3.A case of prenatal ultrasonographic diagnosis of Roberts syndrome.
Yong Hoon CHO ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN ; Young Youn CHOI
Korean Journal of Perinatology 1992;3(1):88-94
No abstract available.
Diagnosis*
4.A case of endometriosis in the abdominal scar following cesarean section.
Young Don YOON ; Hun Ju KIM ; Hae Won JUNG ; Tae Bok SUNG ; Ji Soo BYUN
Korean Journal of Perinatology 1993;4(2):229-234
No abstract available.
Cesarean Section*
;
Cicatrix*
;
Endometriosis*
;
Female
;
Pregnancy
5.A comparison of ritodrine and magnesium sulfate for the suppression of preterm labor.
Tae Bok SONG ; Young Don YOON ; Sang Yook LEE ; Seung Kuk KIM
Korean Journal of Perinatology 1992;3(1):33-41
No abstract available.
Female
;
Magnesium Sulfate*
;
Magnesium*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
6.A case of advanced mixed germ cell tumor.
Yoon Sung NAM ; Hyo Don SOHN ; Young Mi LEE ; Il Soo PARK ; Tae Ho LEE
Korean Journal of Obstetrics and Gynecology 1991;34(12):1788-1794
No abstract available.
Germ Cells*
;
Neoplasms, Germ Cell and Embryonal*
7.Effects of calcium antagonists on contractions of chorionic arteries in normal and preeclampsia placenta.
Hyun KOOK ; Young Don YOON ; Yung Hong BAIK
Journal of Korean Medical Science 1996;11(3):250-257
This study was undertaken to observe the effects of organic or inorganic calcium antagonists and to investigate the involvement of cyclic nucleotides in regulating the vascular tone in the chorionic artery from normal or preeclamptic placenta. KCI and prostaglandin (PG) F2 alpha produced marked and constant contractions in chorionic arterial preparations of both normal and preeclamptic placentas. Nifedipine (NIF), verapamil (VER) and diltiazem (DIL) reduced the tension that had been produced by KCI and PGF2 alpha in a concentration-dependent fashion in both preparations, and the potency order of the three agents was NIF> VER > DIL. In preeclamptic arteries, however, the magnitudes of vasodilatation induced by NIF and DIL were much smaller than those in normal chorionic arteries. Mg2+ and Cd2+ also relaxed the tension induced by KCI and PGF2 alpha. In preeclamptic chorionic artery, the vasodilatation induced by Mg2+ was significantly potentiated, while that by Cd2+ was not. Removing endothelium did not alter cyclic GMP content in both preparations. In both preparations contracted by PGF2 alpha, nitroprusside markedly increased cyclic GMP content, but neither cyclic GMP nor cyclic AMP content was affected by acetylcholine, NIF, isopro-terenol, or Mg2+. The above results suggest that neither cyclic AMP nor cyclic GMP is involved in regulating the vascular tone of chorionic artery and that sensitivity of the artery in preeclampsia to the inhibitory action of calcium antagonist might be different from that in normal placenta.
Arteries/physiopathology
;
Calcium Channel Blockers/*pharmacology
;
Cyclic AMP/analysis
;
Cyclic GMP/analysis
;
Dinoprost/pharmacology
;
Female
;
Human
;
Placenta/*blood supply
;
Potassium Chloride/pharmacology
;
Pre-Eclampsia/*physiopathology
;
Pregnancy
;
Vasoconstriction/*drug effects
8.A case of prenatal ultrasonographic diagnosis of thoracic ectopia cordis.
Yung Hyun OH ; Yong Hoon CHO ; Young Don YOON ; Tae Bok SONG ; Bong Suck OH
Korean Journal of Obstetrics and Gynecology 1992;35(7):1065-1070
No abstract available.
Diagnosis*
;
Ectopia Cordis*
9.Evaluation of Culture Proved Tuberculosis Patients.
Eun Kyung LEE ; Jae Yoon KIM ; Young Jin HONG ; Don Hee AHN
Journal of the Korean Pediatric Society 1995;38(5):633-640
No abstract available.
Humans
;
Tuberculosis*
10.A Clinical Study on Coenzyme Q10(Neuquinon(R)) in the Treatment of Congestive Heart Failure.
Jeong Hyun KIM ; Jong Yoon LIM ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1979;9(1):17-22
Coenzyme Q is concentrated in Golgi apparatus membranes and mitochondria, but not in other membranes. Although it is difficult to prove the metabolic action of coenzyme Q administered exogenously in clinical cases, the effect of this substance can be evaluated by criteria based on clinical findings. In an attempt to evaluate the effect of coenzyme Q for the treatment of 67 patients(male 26 cases, female 41 cases) of congestive heart failure, we administered Coenzyme Q1030mg daily for 4 to 8 weeks. Most of them were valvular heart disease(74.6%) and hypertension (14.9%). Clinical effects were evaluated at least 4 weeks later by the criteria using a scoring method of severity of congestive heart failure which was devised by Ishiyama, etc. In summary, a definite effect was found in 13 cases(19%) and a mild effect was observed in 46 cases(69%). During treatment there were no significant side effects, and also no significant changes in heart rate and blood pressure.
Blood Pressure
;
Estrogens, Conjugated (USP)*
;
Female
;
Golgi Apparatus
;
Heart
;
Heart Failure*
;
Heart Rate
;
Humans
;
Hypertension
;
Membranes
;
Mitochondria
;
Research Design
;
Ubiquinone