2.Prevalence and Clinical Features of Probable REM Sleep Behavior Disorder- An Epidemiological Study in Osan City.
Young Min CHOE ; In Young YOON ; Ki Woong KIM ; Sang Don LEE ; Gawon JU ; Joon Hyuk PARK
Sleep Medicine and Psychophysiology 2011;18(1):23-28
OBJECTIVES: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. METHODS: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. RESULTS: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. CONCLUSIONS: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.
Aged
;
Depression
;
Epidemiologic Studies
;
Humans
;
Mass Screening
;
Prevalence
;
Surveys and Questionnaires
;
REM Sleep Behavior Disorder
;
Sleep, REM
3.A case of prenatal ultrasonographic diagnosis of Roberts syndrome.
Yong Hoon CHO ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN ; Young Youn CHOI
Korean Journal of Perinatology 1992;3(1):88-94
No abstract available.
Diagnosis*
4.A Clinical Study on Coenzyme Q10(Neuquinon(R)) in the Treatment of Congestive Heart Failure.
Jeong Hyun KIM ; Jong Yoon LIM ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1979;9(1):17-22
Coenzyme Q is concentrated in Golgi apparatus membranes and mitochondria, but not in other membranes. Although it is difficult to prove the metabolic action of coenzyme Q administered exogenously in clinical cases, the effect of this substance can be evaluated by criteria based on clinical findings. In an attempt to evaluate the effect of coenzyme Q for the treatment of 67 patients(male 26 cases, female 41 cases) of congestive heart failure, we administered Coenzyme Q1030mg daily for 4 to 8 weeks. Most of them were valvular heart disease(74.6%) and hypertension (14.9%). Clinical effects were evaluated at least 4 weeks later by the criteria using a scoring method of severity of congestive heart failure which was devised by Ishiyama, etc. In summary, a definite effect was found in 13 cases(19%) and a mild effect was observed in 46 cases(69%). During treatment there were no significant side effects, and also no significant changes in heart rate and blood pressure.
Blood Pressure
;
Estrogens, Conjugated (USP)*
;
Female
;
Golgi Apparatus
;
Heart
;
Heart Failure*
;
Heart Rate
;
Humans
;
Hypertension
;
Membranes
;
Mitochondria
;
Research Design
;
Ubiquinone
5.The Effect of Corticosteroid Therpy in the Very Premature Infant.
Hye Jeong KIM ; Mi Ja PARK ; Jae Yoon KIM ; Young JIn HONG ; Don Hee AHN
Journal of the Korean Society of Neonatology 1997;4(2):178-186
PURPOSE: Our purpose was to deterrnine the efficacy of maternal corticosteroid therapy on the morbidity of premature infants between 26 and 31 weeks' gestation. METHOD: A total of 62 premature infants between 26 and 31 weeks gestation admitted to pediatric department of National Medical Center from Nov, 1990 to June 1996 were analyzed to evaluate the efficacy of prenatal corticosteroid therapy on the morbidity such as hyaline membrane disease, intreventricular hernorrhage, necrotizing enterocolitis, sepsis, neonatal death, days on ventilation and hospital days. RESULT: Among 62 women who delivered premature infants between 26 and 31 weeks, 22 received betamethasone before delivery and 40 did not. 1) The rate of hyaline membrane disease was less in the betamethasone group (41% vs. 70%, P<0.05). 2) The rate of intracranial hemorrhage was less in the betamethasone group (0 vs. 20%, P<0.05). 3) The days of ventilator care was less in the betamethasone group among survival cases (27+/-3.2 vs. 5.2+/-4.6, P<05). 4) Arnong 14 women who delivered at 26 to 28 weeks, 4 received betamethasone before delivery and 10 did not. The rate of neonatal death was less in the betamethasone group (o% vs. 80%, P<0.05). 5) Among 48 women who delivered at 29 to 31 weeks, 18 received betamethasone before delivery and 30 did not. The rate of hyaline membrane disease was less in the betamethasone group (39% vs. 73%, P<0.05). CONCLUSION: Betamethasone appears to reduce hyaline membrane disease, intraven- tricular hemorrhage, neonatal death and the morbidity significantly in premature infants between 26 and 31 weeks' gestation.
Betamethasone
;
Enterocolitis, Necrotizing
;
Female
;
Hemorrhage
;
Humans
;
Hyaline Membrane Disease
;
Infant, Newborn
;
Infant, Premature*
;
Intracranial Hemorrhages
;
Pregnancy
;
Sepsis
;
Ventilation
;
Ventilators, Mechanical
6.A case of pregnancy complicated by ruptured endometrioma.
Young Don YOON ; Hye Won CHUNG ; Tae Bok SONG ; Sang Woo JUHNG ; Ji Soo BYUN
Korean Journal of Perinatology 1993;4(3):428-432
No abstract available.
Endometriosis*
;
Female
;
Pregnancy*
7.A case of successful neonatal treatment for congenital eleal atresia detected by antenatal ultrasonogram.
Jin Soon PARK ; Tae Bok SONG ; Young Don YOON ; Ji Soo BYUN ; Eun Kyung KIM
Korean Journal of Obstetrics and Gynecology 1992;35(6):915-919
No abstract available.
Ultrasonography*
8.Protein/creatinine ratio in random urine specimens for quantitation of proteinuria in preeclampsia.
Kyeong Seok JANG ; Sang Yook LEE ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN
Korean Journal of Obstetrics and Gynecology 1993;36(7):2147-2151
No abstract available.
Pre-Eclampsia*
;
Proteinuria*
9.A clinical study on the delivery after previous cesarean section.
Hyun Ju KIM ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN
Korean Journal of Obstetrics and Gynecology 1993;36(7):2140-2146
No abstract available.
Cesarean Section*
;
Female
;
Pregnancy
10.A comparison of ritodrine and magnesium sulfate for the suppression of preterm labor.
Tae Bok SONG ; Young Don YOON ; Sang Yook LEE ; Seung Kuk KIM
Korean Journal of Perinatology 1992;3(1):33-41
No abstract available.
Female
;
Magnesium Sulfate*
;
Magnesium*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*