2.Prevalence and Clinical Features of Probable REM Sleep Behavior Disorder- An Epidemiological Study in Osan City.
Young Min CHOE ; In Young YOON ; Ki Woong KIM ; Sang Don LEE ; Gawon JU ; Joon Hyuk PARK
Sleep Medicine and Psychophysiology 2011;18(1):23-28
OBJECTIVES: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. METHODS: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. RESULTS: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. CONCLUSIONS: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.
Aged
;
Depression
;
Epidemiologic Studies
;
Humans
;
Mass Screening
;
Prevalence
;
Surveys and Questionnaires
;
REM Sleep Behavior Disorder
;
Sleep, REM
3.A case of prenatal ultrasonographic diagnosis of Roberts syndrome.
Yong Hoon CHO ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN ; Young Youn CHOI
Korean Journal of Perinatology 1992;3(1):88-94
No abstract available.
Diagnosis*
4.A case of successful neonatal treatment for congenital eleal atresia detected by antenatal ultrasonogram.
Jin Soon PARK ; Tae Bok SONG ; Young Don YOON ; Ji Soo BYUN ; Eun Kyung KIM
Korean Journal of Obstetrics and Gynecology 1992;35(6):915-919
No abstract available.
Ultrasonography*
5.A case of endometriosis in the abdominal scar following cesarean section.
Young Don YOON ; Hun Ju KIM ; Hae Won JUNG ; Tae Bok SUNG ; Ji Soo BYUN
Korean Journal of Perinatology 1993;4(2):229-234
No abstract available.
Cesarean Section*
;
Cicatrix*
;
Endometriosis*
;
Female
;
Pregnancy
6.Evaluation of Culture Proved Tuberculosis Patients.
Eun Kyung LEE ; Jae Yoon KIM ; Young Jin HONG ; Don Hee AHN
Journal of the Korean Pediatric Society 1995;38(5):633-640
No abstract available.
Humans
;
Tuberculosis*
7.The Effect of Corticosteroid Therpy in the Very Premature Infant.
Hye Jeong KIM ; Mi Ja PARK ; Jae Yoon KIM ; Young JIn HONG ; Don Hee AHN
Journal of the Korean Society of Neonatology 1997;4(2):178-186
PURPOSE: Our purpose was to deterrnine the efficacy of maternal corticosteroid therapy on the morbidity of premature infants between 26 and 31 weeks' gestation. METHOD: A total of 62 premature infants between 26 and 31 weeks gestation admitted to pediatric department of National Medical Center from Nov, 1990 to June 1996 were analyzed to evaluate the efficacy of prenatal corticosteroid therapy on the morbidity such as hyaline membrane disease, intreventricular hernorrhage, necrotizing enterocolitis, sepsis, neonatal death, days on ventilation and hospital days. RESULT: Among 62 women who delivered premature infants between 26 and 31 weeks, 22 received betamethasone before delivery and 40 did not. 1) The rate of hyaline membrane disease was less in the betamethasone group (41% vs. 70%, P<0.05). 2) The rate of intracranial hemorrhage was less in the betamethasone group (0 vs. 20%, P<0.05). 3) The days of ventilator care was less in the betamethasone group among survival cases (27+/-3.2 vs. 5.2+/-4.6, P<05). 4) Arnong 14 women who delivered at 26 to 28 weeks, 4 received betamethasone before delivery and 10 did not. The rate of neonatal death was less in the betamethasone group (o% vs. 80%, P<0.05). 5) Among 48 women who delivered at 29 to 31 weeks, 18 received betamethasone before delivery and 30 did not. The rate of hyaline membrane disease was less in the betamethasone group (39% vs. 73%, P<0.05). CONCLUSION: Betamethasone appears to reduce hyaline membrane disease, intraven- tricular hemorrhage, neonatal death and the morbidity significantly in premature infants between 26 and 31 weeks' gestation.
Betamethasone
;
Enterocolitis, Necrotizing
;
Female
;
Hemorrhage
;
Humans
;
Hyaline Membrane Disease
;
Infant, Newborn
;
Infant, Premature*
;
Intracranial Hemorrhages
;
Pregnancy
;
Sepsis
;
Ventilation
;
Ventilators, Mechanical
8.A comparison of ritodrine and magnesium sulfate for the suppression of preterm labor.
Tae Bok SONG ; Young Don YOON ; Sang Yook LEE ; Seung Kuk KIM
Korean Journal of Perinatology 1992;3(1):33-41
No abstract available.
Female
;
Magnesium Sulfate*
;
Magnesium*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
9.A case of advanced mixed germ cell tumor.
Yoon Sung NAM ; Hyo Don SOHN ; Young Mi LEE ; Il Soo PARK ; Tae Ho LEE
Korean Journal of Obstetrics and Gynecology 1991;34(12):1788-1794
No abstract available.
Germ Cells*
;
Neoplasms, Germ Cell and Embryonal*
10.Effects of calcium antagonists on contractions of chorionic arteries in normal and preeclampsia placenta.
Hyun KOOK ; Young Don YOON ; Yung Hong BAIK
Journal of Korean Medical Science 1996;11(3):250-257
This study was undertaken to observe the effects of organic or inorganic calcium antagonists and to investigate the involvement of cyclic nucleotides in regulating the vascular tone in the chorionic artery from normal or preeclamptic placenta. KCI and prostaglandin (PG) F2 alpha produced marked and constant contractions in chorionic arterial preparations of both normal and preeclamptic placentas. Nifedipine (NIF), verapamil (VER) and diltiazem (DIL) reduced the tension that had been produced by KCI and PGF2 alpha in a concentration-dependent fashion in both preparations, and the potency order of the three agents was NIF> VER > DIL. In preeclamptic arteries, however, the magnitudes of vasodilatation induced by NIF and DIL were much smaller than those in normal chorionic arteries. Mg2+ and Cd2+ also relaxed the tension induced by KCI and PGF2 alpha. In preeclamptic chorionic artery, the vasodilatation induced by Mg2+ was significantly potentiated, while that by Cd2+ was not. Removing endothelium did not alter cyclic GMP content in both preparations. In both preparations contracted by PGF2 alpha, nitroprusside markedly increased cyclic GMP content, but neither cyclic GMP nor cyclic AMP content was affected by acetylcholine, NIF, isopro-terenol, or Mg2+. The above results suggest that neither cyclic AMP nor cyclic GMP is involved in regulating the vascular tone of chorionic artery and that sensitivity of the artery in preeclampsia to the inhibitory action of calcium antagonist might be different from that in normal placenta.
Arteries/physiopathology
;
Calcium Channel Blockers/*pharmacology
;
Cyclic AMP/analysis
;
Cyclic GMP/analysis
;
Dinoprost/pharmacology
;
Female
;
Human
;
Placenta/*blood supply
;
Potassium Chloride/pharmacology
;
Pre-Eclampsia/*physiopathology
;
Pregnancy
;
Vasoconstriction/*drug effects