Ambulatory BP monitoring was performed in a patients with pheochromocytoma before and after removal of the tumor. Before surgery, it did not show any significant diurnal variation. But, after surgery the diurnal variation was restored.
Blood Pressure Monitoring, Ambulatory* ; Blood Pressure* ; Humans ; Pheochromocytoma*

A clinical and radiological obsevation was made on 62 cases of urinary tract injury in the Dept. of urology,Chosun Universtiy hospital during the period from January 1979 to December 1983. The results were as follows; 1.Age distribution of the lower urinary tract injury was the highest in the age 41 to 50(39.6%). The sex ratio, maleto female was 6.8:1. 2. The most common cause of the L.U.T.I. was traffic accident in 23 cases (37.1%) and othersare fall down in 15 cases (24.2%), blunt trauma in 13 cases (21.0%), saddle injury in 8 cases(12.9%). 3. Theradiological finding of the bladder injury shows intraperitoneal extravasation in 11 caess(64.7%), extraperitonealextravasation in 5 cases(29.4%), and deformity of bladder in 12 cases(70.6%). 4. The radiological finding of theurethral injury shows extravasation of contrast media in 44 cases(97.8%). venous intravasation in 11 cases(24.4%),penile urethra in 1 case(2.3%). 6. The L.U.T.I. was associated with pelvic bone fracture in 33 cases (53.2%) esp.pubic bone fracture in 24 cases(38.7%). 7. The complication of the L.U.T.I. was urethral stricture in 24cases(38.7%), fistula formation in 3 cases(4.8%), incontinence in 2 cases(3.2%).
Accidents, Traffic ; Congenital Abnormalities ; Extravasation of Diagnostic and Therapeutic Materials ; Female ; Fistula ; Fractures, Bone ; Humans ; Pelvic Bones ; Sex Ratio ; Urethra ; Urethral Stricture ; Urinary Bladder ; Urinary Tract

Pyogenic arthritis remain a difficult problem, despite the availability of a wide range of powerful modernantibiotics. Early and correct diagnosis is imperative to assure the prompt initiation of an effective therapeuticregimen and the prevent of late sequela. Careful clinical, laboratory and roentgenological analysis arefundamental to early and precise diagnosis. Therefore, plain roentgenogram shold not be overlooked. A radiologicaland clinical observation was made in 51 cases of pyogenic arthritis admittted to Chosun University Hospital duringthe period from January 1976 to Dec. 1983 and following results were obtained. 1. Among the 51 cases, 36 cases(70.6%) were male and 15 cases(29.4%) were females. The most prevalent age was 5 to 9 (27.6%). 2. Symptom durationless than 5 days was in 21 cases (41.2%) and more than 31 days was in 6 cases (11.7%). 3. The most common symptomon admission was pain around the involved joint and others are limitation of motion, swelling, tenderness, fever,local heating and erythema. 4. The underlying causes were composed of unknown in 21 cases(41.2%), trauma in 18cases(35.3%), infections focus in 8 cases (15.7%) and iatrogenic reasone 4 cases(7.8%) 5. The msot commonlyaffected joint was hip joint (45.1%). The other affected sites in order of frequency were knee, ankle, shoulder,S-I and elbow joint. In infants and children, hip and knee joint are commonly affected; In adults, knee joint ismost commonly affected. 6. In laboratory findings, the number of W.B.C and E.S.R were increased in 56.9%. Symptomduration more than 31 days in 5 cases were increased E.S,R only. Causative microorganism was isolated in 31 cases;the most common microorganism was Staphylococcus auterus in 22 cases. Others are B-hemolytic Streptococcus,Enterobacteriaceae species and Pseudomonas aeruginosa. 7. In 26 cases(50.9%) of the patients, roentgenographicfinding was negative. The most common radiological findig was soft tissue swelling and the others are include inorder of frequency: joint space widening, small erosions in articular cortex, subchondral osteoporosis. The comonradiological findings of symptom duration more than 31 days in 6 cases were lost of entire cortex, ankylosis andjoint space narrwoing.
Adult ; Ankle ; Ankylosis ; Arthritis ; Child ; Diagnosis ; Elbow Joint ; Erythema ; Female ; Heating ; Hip ; Hip Joint ; Hot Temperature ; Humans ; Infant ; Joints ; Knee ; Knee Joint ; Male ; Osteoporosis ; Pseudomonas aeruginosa ; Staphylococcus

BACKGROUND: During the adolescent growths spurt, iron deficiency becomes more common, particularly with the additional factors of menstrual blood loss in females and the androgen-related rise in hemoglobin concentration in males. This study was conducted to investigate the iron status in the adolescent students. METHODS: Venous peripheral blood was sampled from 178 males(79 of 12-13years, 99 of 15-16years) who were 1st grade students of two boy's middle schools and two high schools and from 186 females(87 of 12-13years, 99 of 15-16years) who were 1st grade students of two girl's middle schools and two high schools. Laboratory procedures included a hemoglobin, hematocrit, serum iron, TIBC and serum ferritin. Transferrln saturation was calculated. RESULTS: 1) Mean values were hemoglobin 13.7+/-0.78 g/dl, hematocrit 40.6+/-2.47%, serum iron 127.6+/-43.02 ug/dl, TIBC 387.9+/-47.73 ug/dl, transferrin saturation 33.3+/-11.38%, and serum ferritin 26.1+/-16.90 ng/ml in 12-13years old males. 2) Mean values were hemoglobin 13.7+/-0.85 g/dl, hematocrit 40.9+/-3.79%, serum iron 99.4+/-34.93 ug/dl, TIBC 387.8+/-45.53 ug/dl, transferrin saturation 26.2+/-9.99%, and serum ferritin in 22.7+/-14.18 ng/ml in 12-13years old females. 3) Mean values were hemoglobin 15.2+/-0.84 g/dl, hematocrit 45.9+/-2.77%, serum iron 144.9+/-51.97 ug/dl, TIBC 419.8+/-52.46 ug/dl, transferrin saturation 34.2+/-10.44%, and serum ferritin 31.2+/-20.91 ng/dl in 15-16years old males. 4) Mean values were hemoglobin 13.2+/-0.89 g/dl, hematocrit 39.9+/-2.78%, serum iron 111.1+/-39.78 ug/dl, TIBC 392.8+/-50.06 ug/dl, transferrin saturation 28.9+/-10.85%, and serum ferritin 21.4+/-17.11 ng/ml in 15-16years old females. 5) The prevalence of iron deficiency was 8.9% and 10.1% in 12-13years and 15-16years old males respectively. In 12-13years and 15-16years old females, the prevalence was 16.1% and 29.3% respectively. The prevalence of iron deficincy anemia was 1.1% and 2.0% in 12-13years and 15-16years old female and absent in male. CONCLUSIONS: Although hemoglobin is normal, we recommend to check other parameters to optimize the identification of individuals with iron deficiency.
Adolescent* ; Anemia ; Female ; Ferritins ; Hematocrit ; Humans ; Iron* ; Male ; Prevalence ; Seoul* ; Transferrin

The antihypertensive efficacy and safety of doxazosin, a selective alpha1-inhibitor, were assessed in 20 patients with essential hypertension. Doxazosin induced a clinically significant reduction in blood pressure(26.0mmHg in systolic blood pressure and 21.7mmHg in diastolic blood pressure) with similar heart rates after 12 weeks therapy. The efficacy of doxazosin therapy was successful in 17 patients(89.5%) and failed in 2 patients(10.5%). The mean dose of the efficacy evaluable patients was 4.4mg/day. most of all patients completed for 12 weeks therapy except one patients who experienced side effects sych as vertigo, dizziness and fatigue. There were no clinically significant laboratory changes before and after the doxazosin therapy. The overall lipid profile indicated a decrease in total cholesterol with increases in HDL-cholesterol. This results indicated that doxazosin given once daily is and effective antihypertensive agent with the additional action of favorably affecting blood lipid level in the treatment of mild-to-moderate hypertension.
Blood Pressure ; Cholesterol ; Dizziness ; Doxazosin* ; Fatigue ; Heart Rate ; Humans ; Hypertension* ; Vertigo

BACKGROUND: Myocardial infarction(MI) in the rat is a model of ventricular dysfunction which is associated with activation of compensatory neurohumoral systems. This stydy was designed to determine the temporal evolution of the regulatory factors-atrial natriuretic peptide(ANP), endothelin(ET), plasma renin activity(PRA) in rats with more than moderate sized MI at 1,4,8 weeks in comparison to normal rats. METHODS AND RESULTS: MI was created in female Sprague Dawley rats weighing 250gms to 300gms by ligating the anterior descending artery. Before sacrifice, hemodynamics were measured and blood was drawn in control rats(n=8) and rats with MI(n=7), 4(n=10), and 8 weeks(n=9) after surgery. Heart weight index increased from 329.0+/-7.3mg/gm at baseline to 380.6+/-18.4mg/gm, 441.1+/-23.2mg/gm at the 1st, 4th, and 8th weeks after MI. Plasma ANP increased in the 1st weeks and remained elevated(16+/-7, 259+/-65, 404+/-72, 494+/-73pg/ml at baseline, 1st, 4th, 8th weeks after MI respectively). Plasma endothelin was suppressed at 4th weeks but elevated at 8th week(7.8+/-0.2, 5.3+/-0.3, 11.9+/-1.3pg/ml at baseline, 4th, 8th weeks respectively). PRA, indirect index of plasma angiotensin also decreased at 4th week but elevated at 8th week(14.9+/-0.3, 9.8+/-1.0, 20.3+/-1.8ng/ml/hr at baseline, 4th, 8th weeks resepctively). CONCLUSION: These results demonstrate a biphasic response of endothelin and PRA after MI despite the inhibitory effects of ANP. These data support the important differential regulation of humoral factors in the evolution of acute MI.
Angiotensins ; Animals ; Arteries ; Atrial Natriuretic Factor ; Endothelins ; Female ; Heart Failure* ; Heart* ; Hemodynamics ; Humans ; Models, Animal* ; Myocardial Infarction ; Plasma ; Rats* ; Rats, Sprague-Dawley ; Renin ; Ventricular Dysfunction

No abstract available.
Adult* ; Humans ; Korea ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*

The incidence of symptomatic thrombosis of umbilical arterial catheterization is 1-3%. Therapeutic options may include: using heparin or low molecular weight heparin, using a thrombolytic agent, or surgical thrombectomy. However, there are insufficient data to recommend any one treatment over the others. Recently, enoxaparin, a low molecular weight heparin, has emerged as a drug of choice for the treatment of neonatal thrombosis due to pharmacologic stability over unfractionated heparin or thrombolytic agents. We report a case of successful treatment of aortic thrombosis after umbilical arterial catheterization with enoxaparin in preterm infants.
Catheterization* ; Catheters* ; Enoxaparin* ; Fibrinolytic Agents ; Heparin ; Heparin, Low-Molecular-Weight ; Humans ; Incidence ; Infant, Newborn ; Infant, Premature* ; Thrombectomy ; Thrombosis* ; Umbilical Cord*

OBJECTIVE: This clinical study investigates the current status of geropsychiatric consultation in Korea, as the geriatric population and the needs for geropsychiatric consultation increase. METHOD: Hospital records of all geriatiric patients (> or =65) consulted to psychiatric department during hospital stay in a general hospital for 18 months (1998. 9. 1-2000. 2. 1) were reviewed retrospectively. Data on somatic illness, psychiatric illness and patterns of consultation were collected and analyzed. RESULT: Total number of patients was 136 (M 50, F 86) and mean age was 72.5 years old. Psychiatric consultation rate for patients above 65 was 2.5%, it was 29.5% among the whole psychiatric consultations. 65.4% was consulted by the Internal Medicine, Orthopedic surgery was the second most frequent referral department. Nonpsychiatric consultations were frequent, a geriatric patient was consulted to 2.7 other different departments on average, during the same period of hospital stay. Sleep disturbance, depressive mood, anxiety/agitation, somatization with normal laboratory findings were the main reasons of psychiatric consultation. 40% of these cases were tried to manage psychiatric problems by consultee. 50% of patients were suffered from depression, followed by delirium and dementia in frequency. Mean lagtime for consultation was 8.4 days, drug compliance was 90.5%. 54.4% of consultations has been followed up more than twice, 7.4% of consultations has required to be followed up more than 5 times. Compliance for consultation follow up during hospital stay was 78.7% and complicance for OPD follow up after discharge was 52.4%. Mean number of drugs being used on the day of consultation was 7.8, among them, 0.9 were psychiatric drugs. psychiatric drugs were prescribed for 51.5% of patients before psychiatric consultation. 2.2 drugs were prescribed by consultant. Disorientation was shown at 33.8%, visual hallucination was shown at 18.4%, sleep disturbance was prevalent at 64.0% of patients. Disorientation found to be associated with age, sleep disturbance, number of nonpsychiatric consultations, number of psychiatric follow up consultations. CONCLUSION: Clinical Variables on geropsychiatric consultation at a general hospital were investigated. Further studies are warranted on geropsychiatric consultation in Korea.
Compliance ; Consultants ; Delirium ; Dementia ; Depression ; Follow-Up Studies ; Hallucinations ; Hospital Records ; Hospitals, General* ; Humans ; Inpatients* ; Internal Medicine ; Korea ; Length of Stay ; Orthopedics ; Referral and Consultation ; Retrospective Studies

BACKGROUND: Few reports have documented the clinical characteristics and treatment outcomes of adult patients with Elizabethkingia meningoseptica infection. METHODS: Medical records of patients over 18 years of age and suspected of having an E. meningoseptica infection from March 1, 2006 to February 28, 2013 were reviewed retrospectively. Their clinical characteristics, antimicrobial susceptibility results, and treatment outcomes were analyzed. RESULTS: E. meningoseptica was isolated from 30 patients. Median age was 68.5 years, and infections were more frequent in males (17, 56.7%). The most common isolation source was sputum (23, 76.7%), and pneumonia was the most common condition (21, 70%) after excluding two cases of colonization. This bacterium was most susceptible to minocycline (27, 90%) and fluoroquinolones, including levofloxacin (20, 66.7%) and ciprofloxacin (18, 60%). The mortality rate due directly to E. meningoseptica infection was 20% (6/30), and uncontrolled pneumonia was the only cause of death. After isolating E. meningoseptica, the numbers of patients with pneumonia (9/9, 100% vs. 12/21, 57.1%), history of hemodialysis (5/9, 55.6% vs. 3/21, 14.3%), tracheostomy (8/9, 88.9 vs. 10/21, 47.6%), and median Charlson comorbidity index score (6 [range, 3-9] vs. 4 [range, 0-9]) were significantly higher in non-survivors than those in survivors (p < 0.05, for each). However, only 12 (40%) patients received appropriate antibiotics. CONCLUSIONS: E. meningoseptica infection most commonly presented as pneumonia in adults with severe underlying diseases. Despite the high mortality rate, the rate of appropriate antibiotic use was notably low.
Adult* ; Anti-Bacterial Agents ; Cause of Death ; Chryseobacterium ; Ciprofloxacin ; Colon ; Comorbidity ; Cross Infection ; Fluoroquinolones ; Humans ; Levofloxacin ; Male ; Medical Records ; Minocycline ; Mortality ; Pneumonia ; Renal Dialysis ; Retrospective Studies ; Sputum ; Survivors ; Tertiary Care Centers* ; Tracheostomy