1.Reconstruction of Foot and Ankle Soft Tissue Defecty by Lateral Supramalleolar Flap
Soo Jung CHOI ; Young Deok YUH ; Chang Ju LEE ; Won Ho CHO ; Ho Guen CHANG
The Journal of the Korean Orthopaedic Association 1995;30(6):1725-1732
In 1988, a new fascioutaneous flap, the Lateral supramalleolar flap, was introduced by Masquelet and Roman. The flap is designed on the lower third of the aspect of leg, and supplied by a cutaneous branch from the perforating branch of the peroneal artery. This perforating branch continues distally deep to the fascia along the anterior ankle and into the foot. This can be use as either proximally based rotation flap or distally based reversed pedicle island flap giving the flap an arc of rotation that allows coverage of the dorsal, lateral and plantar aspects of the foot, the posterior heel and the lower medial portion of the leg. The authors have recently used this flap for 13 cases of foot and ankle soft tissue defect reconstruction and all the cases, except two partial marginal necrosis, good postoperative course. In our opinion, this flap is useful for reconstruction of foot and ankle soft tissue defect which does not need nerve innervation. The main advantages of the flap are as follows 1. It may be a rather large flap(15× 9cm2 ). 2. The pedicle is long(8cm) and easy to dissect. 3. The pivot of the pedicle is distal(sinus tarsi) and allows great local possibilities of coverage. 4. It does not require the sacrifice of a main artery.
Ankle
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Arteries
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Fascia
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Foot
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Heel
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Leg
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Necrosis
2.Two Cases of Treatment with Intrathecal Rituximab for Primary Central Nervous System Lymphoma.
Yong Ho JANG ; Tae Hwan HA ; Deok Hee KIM ; Sung Rok KIM ; Young Jin YUH ; Byeong Seok SOHN ; Hye Ran LEE
Korean Journal of Medicine 2014;87(2):224-228
Primary central nervous system lymphoma (PCNSL) is an aggressive non-Hodgkin's lymphoma (NHL), usually composed of diffuse large B-cells. Although rituximab is known for its curative effect on B-cell NHL, data on the use of intrathecal rituximab for PCNSL are limited. In this report, we present two patients showing relapsed PCNSL with lymphomatous meningitis. Both patients were refractory to conventional methotrexate-based intrathecal chemotherapy. However, after intrathecal rituximab with or without conventional intrathecal chemotherapy, both patients showed stable disease on magnetic resonance brain imaging and cerebrospinal fluid analysis. There were no serious adverse events during each of 3 and 6 cycles with intrathecal rituximab immunotherapy.
B-Lymphocytes
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Central Nervous System*
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Cerebrospinal Fluid
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Drug Therapy
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Humans
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Immunotherapy
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Lymphoma*
;
Lymphoma, Non-Hodgkin
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Meningitis
;
Neuroimaging