1.Clinical and Epidemiological Studies of Cysticercosis.
Young Pio KIM ; Inn Ki CHUN ; Bom Seock HA
Korean Journal of Dermatology 1989;27(5):521-529
Taenia aolium is responsible for producing human intestinal infection with the tapeworm (taeniasis) and the lodging of the larval stage (Cysticercua cellulosae) in numerous organs. especially subcutaneous tissue with the prodution
Cestoda
;
Cysticercosis*
;
Epidemiologic Studies*
;
Humans
;
Subcutaneous Tissue
;
Taenia
2.A case of proliferating tumor unusually occurring on the lnguinal area.
Sang Keun HA ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1993;31(3):434-438
Proliferating trichilemmal tumor is a relatively uncommon tumor which develops preferentially as a solitary tumor on the scalp of elderly women. Histologically, the tumor i epresents a proliferation of the outer root sheath epithelium in a characteristic pattern, but the presense of cellular atypia, dyskera.totic cells and mitotic figures may lead to a false impression of squamous cell carcinoma. We report a case of proliferating trichliemmal tumor in a 70-yeiir-old male who presented with a slowly growing tumor on his right inguinal area for 2 years. This case is unusual in that the tumor occurred on the inguinal are anoher than the scalp in a male.
Aged
;
Carcinoma, Squamous Cell
;
Epithelium
;
Female
;
Humans
;
Male
;
Scalp
3.A Case of Omphalith.
Bom Seock HA ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1989;27(3):325-328
Omphalith generally consists of keratinous materials and sebum. It gradually forms a stone-like hard, dark brown to a black mass in elderly persons with deep umbilical depression and not clean umbilicus. A 75 years old male noticed a brownish black nodule on the umbilical depression 2 weeks ago. He did not try to remove it. This nodule gradually became to project from umbilical depression accompanied with intermittent pain. Removed specimen was brownish black stonelike on projecting polypoid lesion, but in umbilical depression, yellowish brown and not so hard. Histopathological examination showed a small quantity of melanin granules, but no nuclear components of cells.
Aged
;
Depression
;
Humans
;
Male
;
Melanins
;
Sebum
;
Umbilicus
4.Incidence of Abnormal Liver Function and Risk Factors in Male Employees.
Young Ae HA ; Kyeong Dong CHUNG ; Byung Yeol CHUN
Korean Journal of Occupational and Environmental Medicine 2000;12(1):59-69
OBJECTIVES: This study was conducted to estimate the incidence of abnormal liver function and risk factors in male employees of an industry in Ulsan City. METHODS: Five hundreds and seventy nine male employees were selected as the study cohort and 533(92.1%) of them were followed after one year. The blood sample was collected to test for AST, ALT, gamma-GTP, total-cholesterol, fasting blood sugar and a self-administered questionnaire on life style was done. General characteristics(age, marital status, educational level), job department, exposure status for organic solvents, life style(alcohol, smoking, exercise, diet), past history of liver disease, family history of liver disease, drug intake, HBsAg, blood glucose, total-cholesterol were considered as risk factors. The result of liver function test after 1 year follow-up was treated as dependent variable. The operational definition of abnormal liver function was as follows; those who had abnormal liver functions in the two repeated tests with one month interval. RESULTS: The annual incidence of abnormal liver function was 9.6 per 100 and age-standardized incidence was 9.5. BMI, alcohol, past history of liver disease, and meat intake were significantly related to the incidence(p<0.05). In multiple logistic regression analysis, BMI(RR=2.70, 95% CI=1.41-5.16) and alcohol(RR=1.98, 95% CI=1.08-3.60) were proved as the significant variables. By stratified analysis considering changing pattern of alcohol and BMI, the relative risk of the BMI normal-normal and alcohol intake high-high group was 2.24(95% CI=1.09-4.62) and that of the BMI obese-obese and alcohol intake high-high group was 5.66(95% CI=2.69-11.88) compared with that of BMI normal-normal and alcohol intake low-low group. CONCLUSIONS: The age-standardized annual incidence of abnormal liver function was 9.5 per 100 in male employees. Thus, an active effort for reducing alcohol intake and controlling BMI should be done to reduce the incidence.
Blood Glucose
;
Cohort Studies
;
Fasting
;
Follow-Up Studies
;
Hepatitis B Surface Antigens
;
Humans
;
Incidence*
;
Life Style
;
Liver Diseases
;
Liver Function Tests
;
Liver*
;
Logistic Models
;
Male*
;
Marital Status
;
Meat
;
Questionnaires
;
Risk Factors*
;
Smoke
;
Smoking
;
Solvents
;
Ulsan
5.Experience of Vascularized Joint Transfer for Segmental Loss of M-P Joint: A Case Report
Eun Woo LEE ; Jae Myeung CHUN ; Young Joon HA
The Journal of the Korean Orthopaedic Association 1986;21(5):943-947
Restoration of the M-P joint of a damaged or lost joint by trauma, tumor and others is necessary for adequate function of the hand. Several procedure have been described for restoration of the M-P joint. We experienced a case of vascularized joint transter for a lost joint by trauma. After 1 year and 2 months follow-up, there have been no degenerative change and no pain.
Follow-Up Studies
;
Hand
;
Joints
6.Impact of the Discontinuance of Regular Exercise on Serum Lipids.
Byung Yeol CHUN ; Min Hae YEH ; Young Ae HA
Korean Journal of Epidemiology 1996;18(1):76-83
To estimate the impact the discontinuance of regular exercise on serum lipids, we selected 90 healthy young adults who were recruited and completed their training course as scheduled(5-week basic physical training and 4-week indoor education) during the period February 1995 to April 1995. Serum lipids, height, and weight were measured three times(Time I: before training, Time II: after 5-week training, Time III: after 4-week detraining). Ninety study subjects were classified as underweight, normal and overweight based on the criteria of Katsura equation. Of 17 underweight subjects, two were weight maintainers and 15 were weight gainers. There was no significant change in serum lipids after detraining among 15 weight gainers. Of 64 normal weight subjects, three were weight losers, 12 weight maintainers and 49 were weight gainers. There was significant increase in total cholesterol after detraining among 12 weight maintainers(P<0.01). In addition to this, there was also significant increase in total cholesterol(P<0. 01), LDL- cholesterol(P<0. 01) and HDL-cholesterol(P<0.05) after detraining among 49 weight gainers. This might be due to the harmful effect of detraining except HDL-cholesterol change. Of nine overweight subjects, only one was weight loser and eight were weight maintainers. There was significant increase in HDL-cholesterol after detraining among 7 weight maintainers (P<0.05). However, there were no significant changes in total cholesterol, triglyceride, LDL-cholesterol and MI index. The harmful effect of detraining was not observed in overweight subjects. In conclusion, the harmful effect of detraining was observed in weight maintainers and weight gainers among normal weight subjects after regular exercise.
Cholesterol
;
Humans
;
Overweight
;
Thinness
;
Triglycerides
;
Weight Gain
;
Young Adult
7.A Case of Benign Neonatal Eruptive Hemangiomatosis.
Bom Seock HA ; Young Ho WON ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1988;26(6):960-966
Benign neonatal eruptive hemangiomatosis is extremely rare congenital multiple hemangiomatic disease without systemic visceral involvement. The akin lesions are usually detected at birth and virtually disappear by the age of 12 months. A female infant of 27 days had three or four flat reddish purple maculopapules on the face from the time of birth. They spreaded into the entire body surface and increased in size forming plaque upto little finger tip size for 3 days. There was no evidence of asociated symptomatic visceral involvement. Histologically they were compatible with capillary angiomatous nevi. They began to resolve into residual hyperpigmented macules necrotizing centrally at 2 months of age and almo. completely resolved at 6 months of age without any treatment.
Capillaries
;
Female
;
Fingers
;
Humans
;
Infant
;
Nevus
;
Parturition
8.Immunohistochemical obervation of EGF,TGF - alpha and EGF-R in psoriatic epidermis.
Sang Keun HA ; Seung Chul LEE ; Young Ho WON ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1993;31(1):72-75
Epidermal growth factor(KGF) and transforming growth factor arpha(TGF-a) are polypeptides of 53 amd 50 amino acid residuies. Both bind to epidermal growth factor receptor (EGR-R) leading to phosphorylation of the receptor, enhancement of its tyrosine-specific kinase activity and ultimately to stimulation of cell growth. To study he role of EGF, TGF-a, and EGF-R in differentiation and hyperproliferation of cell, we se lected psoriasis vulgaris, because the affected keratinocyte may house both an abnormally increased proliferative capacity and an abnormally differentiated state. The biopsy specimens were taken from involved and uninvolved skin of 20 patients with psoriasis and immunoperoxidase studies with formalin-fixed paraffin-embedded tissues were performed with EGF, TGF-a and EGF-R useing the Vectastain ABC irnmunoperoxidase stain system. The antibodies were used at a concentration of 6 ug/ml In involved psoriatic skin, distributions of TGF-a and EGF-R were increased in all layers of epidermis as compared to normal, uninvolved psoriatic skin, in which chev were showed to the basal and parabasal layers. However, distribution of EGF was weekly positive in the basal layers of epidermis in both involved and uninvolved skin with no difference between toem. These results suggest that increased distribution of TGF-a and EGF-R may be involved in hypoproliferative state of epidermal keratinocytes in psoriatic lesion.
Antibodies
;
Biopsy
;
Epidermal Growth Factor
;
Epidermis*
;
Humans
;
Keratinocytes
;
Peptides
;
Phosphorylation
;
Phosphotransferases
;
Psoriasis
;
Receptor, Epidermal Growth Factor
;
Skin
;
Transforming Growth Factors
9.Haemorrhagic Gangrene of Skin Caused by Aeromonas hydrophila.
Bom Seock HA ; Young Ho WON ; Inn Ki CHUN ; Young Pio KIM
Annals of Dermatology 1989;1(2):98-101
Aeromonas hydrophila is a motile gram negative rod which exists in soil and water. It can cause septicemia in persons with severe immune deficiency. Occasionally it is one of the etiologic agents of the gangrenous skin disease similar to the gangrene caused by Vibrio vulnificus septicemia. A 42-year-old farmer had been suffering from liver cirrhosis for about 3 years. He had episodes of melena and hematernesis for 2 days prior to coming to the emergency room but had no skin lesions. On the 2nd hospital day, painful, erythematous and edematous skin lesions developed on his left arm and on the 3rd hospital day, several purpuras and hemorrhagic bullae developed on his left arm and leg. In the tissue, blood and blister fluid, numerous gram negative rods were identified by direct smear and culture. The bacterial identification studies from blood and blister fluid revealed A. hydrephda.
Adult
;
Aeromonas hydrophila*
;
Aeromonas*
;
Arm
;
Blister
;
Emergency Service, Hospital
;
Farmers
;
Gangrene*
;
Humans
;
Leg
;
Liver Cirrhosis
;
Melena
;
Purpura
;
Sepsis
;
Skin Diseases
;
Skin*
;
Soil
;
Vibrio vulnificus
;
Water
10.The Relationship between Change in Obesity Indices and Change in Serum Lipids in Adult Male Workers.
Young Ae HA ; Byung Yeol CHUN ; Sin KAM ; Sung Kook LEE ; Min Hae YEH
Korean Journal of Preventive Medicine 1996;29(3):439-450
This study was conducted to evaluate the relationship between change in obesity indices and change in serum lipids in adult male workers. Two-hundred-eight adult male workers of an industry in Taegu city were followed-up from 1991 to 1995. Height, weight, circumferences of hip and waist, blood pressure were measured and serum lipids were analysed. Data on life style were obtained using self-administered questionnaires. Mean differences of anthropometric measurements between 1991 and 1995 were as follows; 1.63kg in weight, 3.61cm in waist circumferences, 4.23cm in hip circumferences, 0.52kg/m2 in BMI and -0.021 in WHR. Those of lipids were as follows; 15.09mg/dl in total cholesterol, 20.43mg/dl in triglyceride, 9.40mg/dl in HDL-cholesterol, 2.87 in MI-index(p<0.01) and 350mg/dl in LDL-cholesterol. The changed value of BMI and Katsura index were strongly correlated with that of total cholesterol(r=0.174, p<0.05), the changed value of BMI correlated with that of triglyceride(r=0.374, p<0.01) and the changed value of weight correlated with that of MI index(r=-0.173, p<0.05). The changed value of WHR was significantly correlated with that of total cholesterol(r=0.162, p<0.05), however, was not significantly correlated with HDL-cholesterol, LDL-cholesterol, triglyceride and MI index. The changed value of weight, BMI and Katsura index were correlated with that of triglyceride(r=0.262, p<0.01; r=0.267, p<0.01; r=0.258, p<0.01) and the changed value of MI index(r=-0.143, p<0.05; r=-0.158; r=-0.144, p<0.01), adjusting the pattern of change in life style. The changed values of HDL-cholesterol and MI index between 1991 and 1995 in low WHR group were significantly higher than those in high WHR group(p<0.05, p<0.01), adjusting the baseline value of them. Similar pattern was observed when considering Katsura index. When stratifying by BMI value of 1991, in low BMI group, the changed value of HDL-cholesterol and MI index showed the same pattern as above, however the of triglyceride was statistically higher in obese group than in non obese group(p<0.05). In conclusion BMI might be a better indicator to predict serum lipids change than other obesity indices.
Adult*
;
Blood Pressure
;
Cholesterol
;
Daegu
;
Hip
;
Humans
;
Life Style
;
Male*
;
Obesity*
;
Surveys and Questionnaires
;
Triglycerides
;
Waist Circumference