1.The Scope of HCV Vaccine Development.
The Korean Journal of Hepatology 1997;3(2):108-113
No abstract available.
2.Factors Influencing Regeneration of Calvarial Defects in Rats.
Sung Chul LIM ; Young Sook KIM
Korean Journal of Pathology 1999;33(11):999-1008
An experimental study was done to evaluate factors influencing guided regeneration of bone in standardized calvarial bony defect. An 8 mm circular transosseous calvarial bony defect was made. Various material such as demineralized freeze-dried bone (DFDB), BioMesh , Millipore filter and its combination was placed in the bony defect. A sequential histopathologic, histochemical, immunohistochemical, and histomorphometric studies were done on the guided bone regeneration in the calvarial bony defect. Bone formation was sigificantly enhanced when the DFDB was retained within the bony defect with a protective bioabsorbable membrane. Inframembranous DFDB-filling was required to prevent collapse of the membrane and preserve spaces for bone regeneration. The bioabsorbable membrane should presumably remain intact for longer than at least 5 weeks to facilitate bone regeneration. The new bone formation was dependent on the barrier-effect (preserving secluded spaces) and inflammation-inducing property of membrane, and guiding bone regeneration of the grafts. Macrophages recruited by grafts were partly involved in decrease of bone regeneration via the sequential events of release of fibronectin, chemotactic effect of the fibronectin to fibroblasts, and collagen lay-down.
Animals
;
Bone Regeneration
;
Collagen
;
Fibroblasts
;
Fibronectins
;
Macrophages
;
Membranes
;
Micropore Filters
;
Osteogenesis
;
Rats*
;
Regeneration*
;
Transplants
3.A Case of Metastatic Cutaneous Squamous Cell Carcinoma Arising in Chronic Osteomyelitic Focus.
Sung Yeol LEE ; Young Chul KYE ; Young Woo CINN
Korean Journal of Dermatology 1988;26(3):442-446
No abstract available.
Carcinoma, Squamous Cell*
;
Osteomyelitis
4.A Case of Impetigo Herpetiformis.
Sung Yeol LEE ; Young Chul KYE ; Young Woo CINN
Korean Journal of Dermatology 1988;26(5):724-728
We report herein a case of impetigo hepetiformis treated with etretinate. The patient was 30 year old female in the 7th month of her second pregnancy, who had suffered from generalized coalesced pustular eruption with slightly itching and hurning sensation with fever on whole body except face, both had and foot. The euption began as an erythemations patch which developed pustules along the mar gin. I'here was extensian by the develupment of fresh peripheral pustules and coaleence of these patches. Histopathological findings showed hyperkeratosis, subcorneal spongiform pustule, spon,iosis in the epidermis and vascular proliferation in the devmis, She was treated successfully with etretinate for 4 weeks.
Acitretin
;
Adult
;
Epidermis
;
Etretinate
;
Female
;
Fever
;
Foot
;
Humans
;
Impetigo*
;
Pregnancy
;
Pruritus
;
Sensation
5.Molecular genetic analysis of non-transferable antimicrobial resistance of shigella isolates.
Sung Yong SEOL ; Young Chul KWON ; Je Chul LEE ; Yoo Chul LEE ; Dong Taek CHO
Journal of the Korean Society for Microbiology 1992;27(2):125-141
No abstract available.
Molecular Biology*
;
Shigella*
6.Airway Obstrauction during Endotracheal Anestheaia - Case report.
Young Chul LEE ; Ki Young LEE ; Sung Chul CHOI
Korean Journal of Anesthesiology 1987;20(3):432-434
Acute airway obstruction during endotracheal anesthesia is embarrassing and critical situation which requires early diagnosis and immediate management. The authors experienced extremely high inspiratory resistance and declared expiration time during endotracheal anesthesia for right pneumonectemy of lung cancer in the left decubitus position. A foreign material was suspected to be dislodged in the trachea distal to the endotrac-heal tube. But the surgical procedure did not allow to change the tube for examination. Ventilation was managed by rotating and moving the endotracheal tube frequently. After extubation, the patient expectorated a polypoid mass and the cause of the obstru-ction was proved to be a result of the detached and dislodged tumor mass of the lung, in diameter 3X1.5 cm.
Airway Obstruction
;
Anesthesia
;
Early Diagnosis
;
Humans
;
Lung
;
Lung Neoplasms
;
Trachea
;
Ventilation
7.A Case Report of Heterotopic Pregnancy after IVF-ET.
Chul Min PARK ; Sung Yop KIM ; Young Soo SON
Korean Journal of Fertility and Sterility 2005;32(4):353-358
Heterotopic pregnancy is named when an extrauterine (ectopic) pregnancy coexists with an intrauterine pregnancy simultaneously by many causes such as PID (pelvic inflammatory disease), endometriosis, IUD (intrauterine device), previous pelvic surgery and others. This is very rare in general population, with a range of occurrence estimated between 1:7963 and 1:30000. But recently the incidence has increased as the uses of ARTs (assisted reproductive technologies) including ovulation induction, IVF-ET (in-vitro fertilization and embryo transfer) and GIFT (gamete intrafallopian transfer) increase. Because this has high maternal morbidity, mortality and fetal loss, early diagnosis and proper management is very important. We report a case of heterotopic pregnancy following IVF-ET with a brief review.
Early Diagnosis
;
Embryonic Structures
;
Endometriosis
;
Female
;
Fertilization
;
Incidence
;
Mortality
;
Ovulation Induction
;
Pregnancy
;
Pregnancy, Heterotopic*
8.A Case of Apocrine Hidrocystoma.
Sung Dae KWON ; Young Chul KYE ; Soo Nam KIM
Annals of Dermatology 1999;11(3):179-181
Apocrine hidrocystoma is an uncommon benign tumor derived from the secretory segment of apocrine sweat glands and another name for it is apocrine cystadenoma. A 48-year-old female patient had a solitary, translucent red-brownish cystic nodule, 10 × 6 × 7mm in size, on the periorbital area of her left eye. The lesion had enlarged very slowly for 25 years. We excised the lesion and identified it as apocrine hidrocystoma. This is a case of apocrine hidrocystoma with typical clinical and histopathological findings.
Cystadenoma
;
Female
;
Hidrocystoma*
;
Humans
;
Middle Aged
;
Sweat Glands
9.Resurfacing of Pitted Facial Acne Scars with a Pulsed Erbium: YAG laser.
Sung Dae KWON ; Soo Nam KIM ; Young Chul KYE
Annals of Dermatology 1999;11(1):5-8
BACKGROUND: Laser resurfacing has beneficial effects for the treatment of several skin conditions. Recently, the pulsed erbium:YAG laser has been shown to be a highly effective treatment for several kinds of pitted facial scars. OBJECTIVE: The purpose of this study was to assess the efficacy and safety of pulsed erbium:YAG laser skin resurfacing at the setting of low or high energy for pitted acne scars. METHODS: 65 patients with pitted acne scars were included in this study. All patients had skin types III or IV. All patients were instructed to use tretinoin cream 0.05% nightly for 2-4 weeks prior to the laser treatment. The pulsed erbium:YAG laser with a 2 mm handpiece at the setting of 500 mJ/pulse, 3.5-5 W in 45 patients and 1,000 mJ/pulse, 7-10 W in 20 patients was used. Two weeks after laser treatment, topical application of hydroquinone 4%, tretinoin 0.05%, and hydrocortisone 1% cream was recommended for 2-4 weeks. Facial photographs were obtained at baseline and 2 week intervals postoperatively. The results of treatment were evaluated for the changes of skin texture and color at 1 month, 3 months, and 6 months. RESULTS: In 45 cases treated with 500 mJ/pulse energy, pitted acne scars were improved about 46.7 % on average and no erythema and postinflammatory hyperpigmentation was observed after 6 months. In 20 cases treated with 1,000 mJ/pulse energy, pitted acne scars were improved about 64% on average and erythema in two patients and postinflammatory hyperpigmentation in one patient were observed after 6 months. CONCLUSION: The results of laser treatment for pitted facial acne scars at the setting of high energy are better than those of laser treatment at the setting of low energy.
Acne Vulgaris*
;
Cicatrix*
;
Erbium*
;
Erythema
;
Humans
;
Hydrocortisone
;
Hyperpigmentation
;
Lasers, Solid-State*
;
Skin
;
Tretinoin
10.Immunohistochemical study on the brain serotonergic neurons of diabetic rats.
Sung Chul KIM ; Young Buhm HUH ; Jin Hwa YOO
Korean Journal of Anatomy 1993;26(3):338-351
No abstract available.
Animals
;
Brain*
;
Rats*
;
Serotonergic Neurons*