1.Dementia in Neruology.
Journal of the Korean Neurological Association 1985;3(1):17-24
No abstract available.
Dementia*
2.A new estimate of prevalence of dementia of the alzheimer type among the eldrely by Three-Phase approach in Jookjang-Myun, Youngil County, Kyungpook Province.
Jong Han PARK ; Hyo Jin KO ; Young Choon PARK
Journal of Korean Neuropsychiatric Association 1993;32(3):430-438
No abstract available.
Dementia*
;
Gyeongsangbuk-do*
;
Prevalence*
3.In vitro antibacterial activity of WCM 302, a substance obtained from culture filtrate of streptomyces sp. 302, against staphylococcus aureus.
Woon Seob SHIN ; Joo Young PARK ; Choon Myung KOH
Journal of the Korean Society for Microbiology 1992;27(6):493-500
No abstract available.
Staphylococcus aureus*
;
Staphylococcus*
;
Streptomyces*
4.2 cases of male urethral diverticulum combined with stone.
Hyun Chul SHIN ; Young Soo KIM ; Tong Choon PARK
Yeungnam University Journal of Medicine 1992;9(2):416-421
Male urethral diverticulum is uncommon lesion, furthermore calculus formation within the male urethral diverticulum is very rare. Generally, urethral diverticula are classified as congenital and acquired. The majority of male urethral diverticula are acquired and approximately 10 to 20 per cent are congenital. Acquired urethral diverticula in the male may arise from many sources, including infection (prostatic abscess, infection of periurethral glands, hematoma or schistosomiasis), obstruction (stricture, impacted stone, Cunningham clamp or condom catheter) and trauma (instrumentation, external injury and pelvic fracture). Calculi formation is more common in the acquired diverticulum owing to stagnation of urine and infection. These calculi in the diverticulum usually are solitary and may attain considerable size with predisposing factors, 1) a ureteral or bladder calculus that is lodged in the urethra 2) urethral trauma or stricture, 3) calcification around a foreign body or hair. The treatment of urethral diverticulum combined with stone is excision of the diverticula with removal of stone. We treated two cases of urethral diverticulum combined with stone in the male, and report with review of literature.
Abscess
;
Calculi
;
Causality
;
Condoms
;
Constriction, Pathologic
;
Diverticulum*
;
Foreign Bodies
;
Hair
;
Hematoma
;
Humans
;
Male*
;
Ureter
;
Urethra
;
Urinary Bladder Calculi
5.Optimum Culture Conditions for Production of Proteinases secreted by Candida albicans , C. tropicalis , and C. parapsilosis.
Choon Myung KOH ; Kyoung Ho LEE ; Woon Seob SHIN ; Joo Young PARK ; Hyun Sook PARK
Journal of the Korean Society for Microbiology 1997;32(4):421-428
In the present study, culture conditions to secrete proteinases from C. albicans, C. tropicalis and C. parapsilosis were examined. All three Candida species were found to secrete proteinases from acceleration phase to stationary phase, although the proteinase activities in culture filtrate were maximal during late exponential or early stationary phase. The proteinase activity in the culture filtrate of C. albicans cells grown at 30'C, was much higher than those grown at either 20 or 37'C. In culture of C. tropicalis and C. parapsilosis, the highest activity was found in culture filtrate grown at 37C. C. albicans secreted proteinases well in medium at initial pH 4.0-7.0. The optimal initial pH of medium for proteinase secretion was 7.0 for C. tropicalis and 5.0-6.0 for C. parapsilosis. All three Candida species secreted proteinases to greater amount in aerobic state. The most effective carbon source for proteinase secretion was xylose, glucose, maltose and sucrose for C. albicans, xylose for C. tropicalis and trehalose for C. parapsilosis. The effects of proteins, hydrolyzed proteins, ammonium sulfate as a sole nitrogen source on proteinase secretion were examined. Bovine serum albumin was the most effective nitrogen source of those tested and a little proteinase activity was detected in the culture filtrates when yeast cells were incubated in the medium containing ammonium sulfate. C. parapsilosis secreted proteinases to greater amount than the other Candida species in all nitrogen sources under study, indicating that C. parapsilosis proteinase would not be a inducible but a constitutive enzyme.
Acceleration
;
Ammonium Sulfate
;
Candida albicans*
;
Candida*
;
Carbon
;
Glucose
;
Hydrogen-Ion Concentration
;
Maltose
;
Nitrogen
;
Peptide Hydrolases*
;
Serum Albumin, Bovine
;
Sucrose
;
Trehalose
;
Xylose
;
Yeasts
6.Regulation of TNF - alpha Gene Expression in Human Fetal Astrocytes.
Hye Myung RYU ; Joo Young PARK ; Sun Ju CHOI ; Hyun Sook PARK ; Choon Myung KOH
Journal of Bacteriology and Virology 2001;31(3):291-297
Tumor necrosis factor-n (TNF - alpha) involved in the pathogenesis of multiple sclerosis and contribute to the degeneration of oligodendrocytes as well as neurons. TNF - alpha is produced by miocroglia and astrocytes, which also produce hormones and cytokines that influence its biological activity. Astrocytes, the major glial cells in the CNS, are capable of producing TNF - alpha at both the mRNA and protein levels in response to interleukine-1 (IL-1) or TNF - alpha. Two immunosuppressive cytokines, transforming growth factor - beta (TGF - beta) and IL-10, have been shown to influence glial cell function. TGF - beta can modulate the activity of glial cells by inhibiting interferon-gamma (IFN - gamma) induced expression of class II major histocompatibility complex (MHC) molecules on astrocytes and microglia. To explore the role of astrocytes in the production of TNF - alpha, astrocytes were pretreated with IL-10 or TGF - beta and then stimulated with IL-1p to determine their effects on TNF - alpha production. The secretion of TNF - alpha by human fetal astrocytes was markedly inhibited by TGF - beta at a low concentration. In contrast IL-10 had no effect on TNF - alpha mRNA level. These results show that TGF - beta may regulate the expression of TNF - alpha in activated human fetal astrocytes.
Astrocytes*
;
Cytokines
;
Gene Expression*
;
Humans*
;
Interferon-gamma
;
Interleukin-10
;
Major Histocompatibility Complex
;
Microglia
;
Multiple Sclerosis
;
Necrosis
;
Neuroglia
;
Neurons
;
Oligodendroglia
;
RNA, Messenger
;
Transforming Growth Factors
7.Identification of Differentially Expressed Genes in Human Fetal Astrocytes.
Hye Myung YOO ; Hyun Sook PARK ; Hyun Chul CHO ; Choon Myung KOH ; Joo Young PARK
Journal of the Korean Society for Microbiology 2000;35(5):374-374
No Abstract Available.
Astrocytes*
;
Humans*
8.Clinical Competence and Organizational Socialization according to Communication Style of Preceptors as Perceived by New Nurses.
Young Choon PARK ; Hyoung Sook PARK
Journal of Korean Academy of Fundamental Nursing 2016;23(1):42-50
PURPOSE: The purpose of this study was to examine clinical competence and organizational socialization according to communication style of preceptors as perceived by new nurses. METHODS: From May 1 to July 31, 2014, data were collected from 180 new graduated nurses who had been working for 3~12 months in hospitals in Busan and one in Gyungnam. Data were analyzed using descriptive statistics, t-test, ANOVA, and Pearson correlation coefficients. RESULTS: Preceptors's communication style perceived by the new nurses included supportive type, reflective type, emotive type, and directive type in order of precedence. The average score for clinical competence was 2.82+/-0.31, and the average score for organizational socialization was 3.05+/-0.40. There were significant differences in nurses' clinical competence(F=9.087, p<.001) and organizational socialization (F=30.129, p<.001) according to preceptor's communication style. CONCLUSION: Results indicate that supportive and emotive communication styles of preceptors were important factors in the success of the preceptees' clinical competence and organizational socialization.
Busan
;
Clinical Competence*
;
Gyeongsangnam-do
;
Preceptorship
;
Socialization*
9.Evaluation of hepatic pliability using supine and erect abdominal x-rays
Se Young JUNG ; Cheol Kyu PARK ; Seog Hee PARK ; Choon Yul KIM ; Yong Whee BAHK
Journal of the Korean Radiological Society 1986;22(4):499-502
Although many approaches have been attempted in the evaluation of liver size such as measurement of length,area and volume, the linear measurements have been used most frequently because of simplicity. We measured theliver size using 4 linear measurements for evaluation of hepatic pliability on plain abdominal film in the erectand the supine position. Our cases consisted of 125 persons who have no symptom or signs clinically and havenormal liver function test. The results were as follows: 1. The measurements of the liver size using diagonaldiameter(DD), oblique diameter of right lobe(OD), midline vertical diameter(MD) and height of right dome of theliver(HD) were ; 19.6+-1.8cm, 13.7+-1.6cm, 2.03+-0.4cm in the supine position; and 20.5+-2.1cm, 21.9+-2.1cm,15.4+-2.1cm, 1.87+-0.4cm in the erect position, respectively. 2. The differences of each diameter between erectand supine position were 0.9+-1.0cm in DD, 0.9+-1.0cm in OD and 1.7+-1.4cm in MD, and they were longer in thesupine position (p<0.001). 3. The HD was slinghtly longer in the supine position than in the erect position(p<0.001). 4. Among the 4 measurements, the largest difference of linear diameter between the erect and the supineposition was by MD. 5. We found the change or size and shape of the normal liver in the different position.
Humans
;
Liver
;
Liver Function Tests
;
Pliability
;
Supine Position
10.A case of giant lymph node hyperplasia in the spermatic cord.
Hyun Chul SHIN ; Young Soo KIM ; Tong Choon PARK ; Young Ran SHIM
Yeungnam University Journal of Medicine 1992;9(1):175-180
Giant lymph node hyperplasia (Castleman's disease) is a rare disease, which represents a peculiar form of lymph node hyperplasia. Generally, it has been considered as benign and localized disease but recently, revealed malignant transformation in some cases of multicentric form. It usually occurs on the mediastinum and occasionally neck, lung, axilla, mesentery, broad ligament, retroperitoneum or soft tissue of extremities. Histopathologically, it is divided into hyaline vascular or plasma cell type and the former is characterized with prominent vascular proliferation and hyalinization in the central portion and tight concentric layering of lymphocytes at the periphery of the follicles (mantle zone) and the latter is characterized by a diffuse plasma cell proliferation in the interfollicular area. From the point of view of clinical presentation, it has been divided into solitary form, which presents as a localized mass located most commonly in the mediastinum, and multicentric form, which occurs multiple location and has systemic manifestation and transformation into malignancy. Herein we report a case of Giant lymph node hyperplasia occurring in the left spermatic cord in a 58-year old male with brief review of literatures.
Axilla
;
Broad Ligament
;
Extremities
;
Female
;
Giant Lymph Node Hyperplasia*
;
Humans
;
Hyalin
;
Hyperplasia
;
Lung
;
Lymph Nodes
;
Lymphocytes
;
Male
;
Mediastinum
;
Mesentery
;
Neck
;
Plasma Cells
;
Rare Diseases
;
Scrotum
;
Spermatic Cord*