1.Brain MRI findings in schizophrenics.
Young Bong LEE ; Young Cho CHUNG ; Gam HUR
Journal of Korean Neuropsychiatric Association 1993;32(6):1026-1035
No abstract available.
Brain*
;
Magnetic Resonance Imaging*
2.Hematoimmunological prognosis of AIDS patients in Korea.
Young Keol CHO ; Young Bong KIM ; Byung Sun CHOI ; Goon Jae CHO ; Young Ho WON ; Yung Oh SHIN
Korean Journal of Infectious Diseases 1992;24(3):161-169
No abstract available.
Humans
;
Korea*
;
Prognosis*
3.Correlation between the response of multitest@ CMI and CD4+ T cell count in HIV infected persons.
Young Keol CHO ; Kyung Soon CHEONG ; Won Kyung JUN ; Young Bong KIM ; Yung Oh SHIN
Journal of the Korean Society of Virology 1992;22(1):53-59
No abstract available.
Cell Count*
;
HIV*
;
Humans
5.Epidemiological characteristics of HIV infected homosexuals in Korea(1992).
Young Keol CHO ; Yung Oh SHIN ; Young Bong KIM
Korean Journal of Preventive Medicine 1993;26(4):541-550
In order to investigate psychological and behavioral characteristics homosexuals and to present evidence that homosexuals are in danger of HIV infection in Korea, this study was done by self-administered questionnaire and then direct interview with the 28(35%) HIV infected homosexual/bisexuals of 79 HIV infected persons reported in 1992. Homosexuals without heterosexual activity were 9 and the others were bisexuals. Sixty-five percent of respondents had a guilty conscience for their homosexual activity. Twenty(71%) were in twenties and 5(18%) in thirties. Twelve(43%) were detected via health card checking by health office, 21% by blood donation, 18% by hospital visit, and 7% by partner notification. Motivations for homosexual activity were curiosity(36%), temptation or recommendation(14%) and compulsion(11%). Eighteen(72%) never used condom on anal sex. Nine of 26 respondents had experience for anal sex with foreigners. Fourteen(54%) of 26 respondents had history for sexually transmitted diseases. Fightly percent did not have sexual contact after HIV infection and the others usually used condom. It was confirmed that over 57% of the respondents were infected within 1 year before HIV diagnosis and over 82% within 2 years. These data suggest that HIV infection among homosexual group is rapidly spreading.
Bisexuality
;
Blood Donors
;
Condoms
;
Conscience
;
Contact Tracing
;
Surveys and Questionnaires
;
Diagnosis
;
Emigrants and Immigrants
;
Heterosexuality
;
HIV Infections
;
HIV*
;
Homosexuality*
;
Humans
;
Korea
;
Surveys and Questionnaires
;
Sexual Behavior
;
Sexually Transmitted Diseases
6.Sequence Analysis of C2-V3 Region of Human Immunodeficiency Virus Type 1 gp120 and its Correlation with Clinical Significance : the Effect of Long-Term Intake of Korean Red Ginseng on env Gene Variation.
Young Keol CHO ; Young Bong KIM ; Yoo Kyum KIM ; Hee Jung LEE ; Won Il OH
Journal of the Korean Society for Microbiology 1997;32(5):611-623
Human immunodeficiency virus type 1 (HIV-1) phenotype plays an important role in the pathogenesis of AIDS. The presence of syncytium-inducing (SI) HIV-1 isolates in infected persons is associated with a rapid decline of CD4+T cells (CD4+), rapid disease progression, and reduced survival time after AIDS diagnosis. We have reported the effects of Korean red ginseng (KRG) on HIV-1 infected patients. To investigate whether KRG affects HIV-1 at gene level and there is a correlation between genotype and decline of CD4+, the C2-V3 region of env gene from 65 HIV-1 isolates were cloned and sequenced. Distributions of subtype were subtype B 57 (88%), subtype A 4 (6%), subtype C 2 (3%), subtype G 1 (2%), and subtype H 1 (2%). The prevalences of SI according to the number of CD4+ are as follows; 40% (6/15) in CD4+ <100/ ul, 14% (1/7) in 100-200/ul, and 2% (1/43) in >200/ul. Seventy-five percent (6/8) of SI were detected in rapid progressor with the decline of CD4+ over 60/ul per year. The correlation between SI genotype and the detection of immune complex dissociated (ICD) p24 antigen was significant (p<0.001). In the 40 patients followed-up over 60 months by CD4+, there was significant correlation between annual decrease of CD4+ and duration of KRG intake (R=-0.380, p<0.01), whereas no correlation between CD4+ and zidovudine (ZDV) was observed. The intrapatient variation of amino acid level showed significant inverse correlation with the months of KRG intake (R=-0.47, p<0.01). These results suggest that the determination of genotype by C2- V3 sequencing may be used for the evaluation of prognosis of AIDS patient, and long-term intake of KRG may prevent or delay the progression from NSI to SI.
Antigen-Antibody Complex
;
Clone Cells
;
Diagnosis
;
Disease Progression
;
Genes, env*
;
Genotype
;
HIV*
;
HIV-1*
;
Humans*
;
Panax*
;
Phenotype
;
Prevalence
;
Prognosis
;
Sequence Analysis*
;
Zidovudine
7.Effect of Korean red ginseng on the levels of serum p24 antigen, ?-microglobulin, and CD4+T cell counts in HIV infected patients treated with AZT(I).
Young Keol CHO ; Young Bong KIM ; Byung Sun CHOI ; Young Sik JANG ; Young Oh SHIN ; Yoo Kyum KIM
Journal of the Korean Society for Microbiology 1993;28(5):409-417
No abstract available.
Cell Count*
;
HIV*
;
Humans
;
Panax*
8.Cord-like Atresia of the Abdominal Aorta Due to Takayasu Arteritis in Middle Aged Woman: A case Report.
Bong Keun LEE ; Sung Rae CHO ; Bong Gyun CHO ; Jae Wha LEE ; Young Duk JOH
The Korean Journal of Thoracic and Cardiovascular Surgery 2001;34(11):870-874
Takayasu arteritis is a chronic non-specific inflammatory arteriopathy that involves primarily the first branches of aortic arch but may also affect the aorta and any of its primary branches. A characteristic trait of the disease is that most of the patients are young females of mainly Asian and South American origin. Recently, we experienced a rare case of Takayasu arteritis which showed a cord-like atresia of abdominal aorta just below renal arteries in 52-year-old woman. We performed a side to side bypass graft from descending thoracic aorta to abdominal aorta just above the aortic bifurcation with a 18mm PTFE(polytetrafluoroethylene) vascular graft. The postoperative course was uneventful.
Aorta
;
Aorta, Abdominal*
;
Aorta, Thoracic
;
Asian Continental Ancestry Group
;
Female
;
Humans
;
Middle Aged*
;
Renal Artery
;
Takayasu Arteritis*
;
Transplants
9.Analysis of predictive factors in the Assessment of Mear-drowning in Children.
Dae Bong JUNG ; Chun Ho KIM ; Yong Bae KIM ; Soo Hyoung CHO ; Nam Soo CHO ; Eun Seok YANG ; Young Bong PARK ; Sang Kee PARK ; Kyung Rye MOON
Journal of the Korean Society of Emergency Medicine 1998;9(3):437-444
Drowning is the second most common cause of accidental death of children in Korea. But the study of near-drowning is very rare in Korea. The purpose of our study is to determine the factors that may influence survival on the basis of submersion time, consciousness state upon admission to hospital, the kinds of water, laboratory findings and neurological outcomes. The survey was performed by a retrospective cohort study on 28 near drowning victims of less than 15 years of age who were admitted to the emergency room in the Chosun University Hospital between May 1988 & May 1997. The results were as follows 1) Sex distribution was 22 males and 6 females. 2) Submersion time was (5 minutes in 9 cases, 5-9 minutes in 6 cases,10-14 minutes in 5 cases,15-19 minutes in 3 cases, > or =20 minutes in 5 cases. 3) Comatose patients upon arrival were 6/7 cases in the death group(86%) and 2/21 cases in the improved group(10%). they had unfavorable outcomes(P<0.05). 4) The first pH value was mean 7.02)0.12 in the death group and mean 7.31 +/-0.13 in the improved group. there was a statistically significant difference between the death and the improved group(P<0.05). 5) The patients who had increased blood glucose concentration were all 7 cases in the death group and 12/22 cases in the improved group(54%). The mean blood glucose concentration was mean 424.7235.6mg/dl in the death group and mean 140.182.7mg/dl in the improved group. There was a statistically significant difference between the death and the improved group(P<0.05). 6) The patients who had pulmonary edema upon arrival were all 7 cases in the death group and 1/21 cases in the improved group(18%). They had unfavorable outcomes(P<0.05). 7) The patients who had been submerged more than 15 minutes were all 7 cases in the death group and 6/21 cases in the improved group(5%). They had unfavorable outcomes(P<0.05). We conclude that pediatric victims of near-drowning can be assigned to high or low likelihoods of unfavorable outcomes with the use of five variables, comatose mentation upon arrival, decreased initial blood pH, increased initial blood glucose concentration, pulmonary edema, and maximum submersion time estimated longer than fifteen minutes. This prediction rule may be useful if it can be validated in another cohort.
Blood Glucose
;
Child*
;
Cohort Studies
;
Coma
;
Consciousness
;
Drowning
;
Emergency Service, Hospital
;
Female
;
Humans
;
Hydrogen-Ion Concentration
;
Immersion
;
Korea
;
Male
;
Near Drowning
;
Pulmonary Edema
;
Retrospective Studies
;
Sex Distribution
10.Epidemic Aseptic Meningitis in 1993.
Ji Yeon CHO ; Hyang Ju KIM ; Ghee Young JUNG ; Jin Keun PANG ; Du Bong LEE
Journal of the Korean Pediatric Society 1995;38(7):901-906
No abstract available.
Meningitis, Aseptic*