Sensitization to Cenasert®, a broad spectrum antimicrobial for the treatment of leukorrhea, is rare. Perineal contact dermatitis due to vaginal suppositories has never been reported in the medical literature. We report a 31-year-old woman, who developed perineal skin eruptions following the treatment of leukorrhea with Cenasert® vaginal suppositories. Patch tests showed positive reactions to Cenasert® suppositories and to the three active ingredients of Cenasert®. Vaginal suppositories can sensitize not only the vagina but also the surrounding perineum due to leakage of the allergen from the vaginal vault.
Adult ; Dermatitis, Allergic Contact* ; Dermatitis, Contact ; Female ; Humans ; Leukorrhea ; Patch Tests ; Perineum ; Skin ; Suppositories* ; Vagina

A small proportion of diabetics treated with exogenous insulin, reportedly ranging from 0.1% to 2%, experience systemic allergic reactions to insulin. We saw a 55-year-old male patient with insulin-dependent diabetes mellitus who had developed an anaphylatic reaction immediately after subcutaneous injections of neutral protamine Hagedorn (NPH) human recombinant insulin. Skin tests with insulins and a passive transfer test demonstrated that his reaction was IgE mediated. Since there were no therapeutic alternatives, desensitization with insulin was done following a slow protocol. It was successful and he was able to resume insulin therapy. During two year follow-up period, he did not developed any adverse reaction to insulin.
Anaphylaxis* ; Diabetes Mellitus, Type 1 ; Follow-Up Studies ; Humans ; Hypersensitivity ; Immunoglobulin E ; Injections, Subcutaneous ; Insulin* ; Insulins ; Intradermal Tests ; Male ; Middle Aged ; Skin Tests

Wet cement can cause caustic ulcers due to its alkalinity. Besides caustic ulcers frequently called cement burn, allergic and irritant contact dermatitides are common in cement workers. Alkalinity of calcium hydroxide in wet cement combined with the effect of pressure and occlusion against skin may result in cement burn. We report two cases of cement burn due to their occupational exposures.
Burns* ; Calcium Hydroxide ; Dermatitis, Contact ; Occupational Exposure ; Occupations ; Skin ; Ulcer

Povidone-iodine(PVP-I) is a widely used antiseptic for the skin because of its low toxicity and high germieidal efficacy, Allergic contact dermatitis to PVP-I is known to be rare. Two patients who recently underwent surgical operations were referred to us due to pruritic well-demarcated eczematous skin lesions around the wounds. Their operation wounds had persisted in spite of the treatments using systemic antibiotics and topical antiseptics. Patch tests were performed with antiseptics including PVP-I, hydrogen peroxide, and benzalkonium chloride which had been used to dress their wounds. The patch tests resulted in positive reactions to PVP-I at the concentrations of 1% in one patient and 0.01% in another.
Anti-Bacterial Agents ; Anti-Infective Agents, Local ; Benzalkonium Compounds ; Dermatitis, Allergic Contact* ; Humans ; Hydrogen Peroxide ; Patch Tests ; Povidone-Iodine* ; Skin ; Wounds and Injuries

No abstract available.
Humans* ; Saponins* ; Skin*

We report a case of fibroma of tendon sheath developed in a 22-year-old woman. The tumor of about 5 years duration was protruding on the volar surface of her 4th finger tip. It was well-demarcated rubbery-hard, and immovable on palpation. The surface on the tumor was smooth and had some telangiectasias. It was asymptomatic and non-tender. The histopathologic findings of excised specimen revealed well-demarcated lobulated mass with widely-spacd: fibroblasts in a hyalinized collagenous matrix. The characteristic slit-like spaces were found in hypoellular and fasciitis-like region. After excision, local recurrence has not been observed for about one and a half years of follow-up period.
Collagen ; Female ; Fibroblasts ; Fibroma* ; Fingers ; Follow-Up Studies ; Humans ; Hyalin ; Palpation ; Recurrence ; Telangiectasis ; Tendons ; Young Adult

We report a case of fibroma of tendon sheath developed in a 22-year-old woman. The tumor of about 5 years duration was protruding on the volar surface of her 4th finger tip. It was well-demarcated rubbery-hard, and immovable on palpation. The surface on the tumor was smooth and had some telangiectasias. It was asymptomatic and non-tender. The histopathologic findings of excised specimen revealed well-demarcated lobulated mass with widely-spacd: fibroblasts in a hyalinized collagenous matrix. The characteristic slit-like spaces were found in hypoellular and fasciitis-like region. After excision, local recurrence has not been observed for about one and a half years of follow-up period.
Collagen ; Female ; Fibroblasts ; Fibroma* ; Fingers ; Follow-Up Studies ; Humans ; Hyalin ; Palpation ; Recurrence ; Telangiectasis ; Tendons ; Young Adult

Infantile hemangiopericytoma deserves separate consideration from adult form of hemangiopericytoma in that it has a benign clinical behavior and distinct histology. We herein report a case of infantile hemangiopericytoma in a 80-day-old male. He had multiple tender subcutaneous nodules on buttock and lower extremities which disappeared spontaneously in 10 months. Microscopically, well circumscribed multiple tumor nodules were seen in the dermis and subcutis and the nodules were consisted of haphazardly packed cells around endothelium-lined vascular slits. Infantile hemangiopericytoma is usually soliitary and spontaneously healed case has not been reported yet.
Adult ; Buttocks ; Dermis ; Hemangiopericytoma* ; Humans ; Lower Extremity ; Male

Nerve sheath myxoma(NSM) is a rare cutaneous neoplasm of uncertain histogenesis. NSM can be divided into two groups; NSM1 (a myxoid NSM) and NSM2 (a cellular neurothekeoma). NSMs are characterized histologically by well-defined, lobular or plexiform dermal proliferation of stellate, spindle-shaped cells embedded in abundant myxoid stroma. A variable amount of nerve fascicles are entrapped within and around the tumor. Two variants of NSM share the same features to a certain degree but differ in cellularity and mucin deposition. We report two cases of NSMs with different clinical and histopathologic features.
Mucins ; Neurothekeoma*

The incidence of mercury sensitivity in millitary personnel without contact dermatitis was investigated using the patch test with 1% ammoniated mercury and 0.1% thimerosal. A questionaire study relating to mercury exposure was also performed in 124 subjects. We also investigated whether the several vaccines curently in use in Korea contain mercury products. The results were as follows . 1. Ammoniated mercury sensitivity was in 10.8% and thimerosal sensitivity was 6.1% in all tested subjects, a similar percentage observed in patch test clinic of the authors. 2. Vaccination history was statistically related significantly, to the senstivity to mercury allergens (P<0.05). 3. All subjects sensitized to thimerosal were also allergic to ammoniated mercury, suggesting crosssensitivity. 4. Hepavax-B, D. P.T., Japanese encephalitis vaccine, and fluvax, currently in use in Korea, contain thimerosal as a preservative.
Allergens ; Dermatitis, Contact* ; Encephalitis, Japanese ; Epidemiology ; Humans ; Incidence ; Korea ; Military Personnel* ; Patch Tests ; Thimerosal ; Vaccination ; Vaccines