1.A Case of A3B.
Young Ae LIM ; Ae Ja PARK ; Seung Hwan CHIN ; Hyae Rim HONG ; Yeung Tak KANG
Korean Journal of Blood Transfusion 1994;5(1):53-56
The results of ABO blood typing in 64-year-old patient with chronic renal and heart failure were positive with anti-B, delayed and weak positive with anti-A in the slide method for the cell typing, mixed-field agglutiniation by light microscopy in the tube method for the cell typing, and also was negative in anti-A, lectin and positive in anti-H, therefore blood typing of this patient was confirmed to A3B.
Blood Grouping and Crossmatching
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Heart Failure
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Humans
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Microscopy
;
Middle Aged
2.Frontal lobe dysfunctions in Parkinson's disease.
Yang Eui HONG ; Ae Young LEE ; Jae Moon KIM
Journal of the Korean Neurological Association 1998;16(2):166-171
A wide range of cognitive impairments and depression can be observed in most patients with Parkinson's disease (PD). But the underlying mechanism of these changes has not to be clarified yet. This study evaluated whether the frontal lobe dysfunctions contribute to the cognitive deficits in PD by comparison with age and education-matched controls. The neuropsychological tests known to be sensitive to frontal lobe dysfunction were performed to 38 patients with PD and matched 24 controls. These were composed of 'Category Fluency Test (CFT)' including objects, animals, & nations and 'Wisconsin Card Sorting Test (WCST)'. General cognition and depression were measured 'Korean Mini-Mental State Examination (K-MMSE)' and 'Beck Depression Inventory (BDI)' respectively. We examined the degree of motor disabilities in PD using the Hoehn-Yahr Stage. Patients with PD were assessed before noon and during the ""On"" time of levodopa to reduce the diurnal variation of mood and drug effects. Although PD patients, compared with controls, showed decreased ability in attention & calculation, memory, and visuo-spatial construction, the most prominent deficit was frontal lobe dysfunction evaluated with WCST and CFTs. Cognitive impairments in PD did not attribute to the discrepancy of education level or associated depression. So we suggest that the frontal lobe dysfunction may play an important role for cognitive impairments in PD.
Animals
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Cognition
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Depression
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Education
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Frontal Lobe*
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Humans
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Levodopa
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Memory
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Neuropsychological Tests
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Parkinson Disease*
3.Dermatophagoides farinae specific IgG-subclass antibody in allergic children.
Young Mi HONG ; Kyung Hyo KIM ; Eun Ae PARK ; Gyoung Hee KIM
Journal of the Korean Pediatric Society 1993;36(10):1351-1358
For determining the distribution of specific IgE and IgG-subclass antibodies and their role in allergic disorders, we measured the serum levels of specific IgG-subclass and IgE antibodies to Dermatophagoides farinae (Df) on 60 atopic children, aged between 8 to 12. All of them had positive skin test to Df, and was grouped into three: children with asthma only (group 1), with rhinitis (group 2), and with them together (group 3). Every data were compared with that of 47 nomal children. ELISA (for IgG and IgG-subclass) and RIA (for IgE) were used. The results are as following. 1) Specific IgE-antibody is significantly higher in all three allergic groups, compared with normal control group. But there was no significant difference between three allergy groups. 2) Specific IgG, IgG1, IgG2 IgG4-antibodies were higher than those in normal control group, but IgG3 was not significant. IgG1 and IgG2 were elevated particularly in patients with asthma and rhintis, but IgG4 was elevated in asthma group. 3) The linear correlation between specific IgE and IgG1-antibody was significant (r=0.286), but IgG4 did not have this correlation with IgE. In conclusion, the levels of specific IgE is essential for the diagnosis of allergies, and IgG1 and IgG4 seem to participate in allergic reactions with a different mechanism.
Antibodies
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Asthma
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Child*
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Dermatophagoides farinae*
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Diagnosis
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Enzyme-Linked Immunosorbent Assay
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Humans
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Hypersensitivity
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Immunoglobulin E
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Immunoglobulin G
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Pyroglyphidae*
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Rhinitis
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Skin Tests
4.A case of transent erythroblastopenia of childhood.
Gi Hong SEO ; Ae Young KIM ; Kyeong Sook CHO ; Jong Dae CHO
Journal of the Korean Pediatric Society 1992;35(4):551-555
No abstract available.
5.Basic Data for Reference Intervals in Koreans for Parameters Produced by Multiplate Platelet Function Analyzer.
Sae Yun BAIK ; Ji Man HONG ; Young Ae LIM
Laboratory Medicine Online 2013;3(4):191-197
BACKGROUND: The Multiplate analyzer (Dynabyte GmbH) has been recently introduced as a platelet function test for patients taking antiplatelet drugs. The study aimed at providing basic data for determining the reference interval of parameters produced by Multiplate in Koreans and to study the factors that influence those parameters. METHODS: Blood was collected from 35 healthy volunteers (female 18, male 17) into tubes containing hirudin or 3.2% sodium citrate. Whole blood platelet aggregations triggered by adenosine-5'-diphosphate (ADP), ADP-high sensitive (ADP+PGE1 only in hirudin samples), arachidonic acid (AA), collagen or thrombin receptor activator peptide (TRAP) were investigated using Multiplate according to the manufacturer's instructions. Data from healthy volunteers for the area under the curve (AUC) were determined from the central 95th percentile of the results. RESULTS: The values of AUC in hirudin samples for all agonists were significantly higher than those in sodium citrate samples. The AUC values in hirudin (sodium citrate) samples were as follows: ADP 38-107 (18-119) U; ADP+PGE1 16-91 U; AA 64-156 (32-117) U; collagen 53-112 (26-108) U; and TRAP 81-163 (49-149) U. The parameters from Multiplate were significantly correlated with leukocyte counts, but not with hematocrit levels. CONCLUSIONS: Although our data were derived from only 35 subjects, the results are expected to be helpful in determining the reference interval at a single institute and may serve as basic data for future cumulative data of reference intervals from multiple institutes in Korea.
Academies and Institutes
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Adenosine Diphosphate
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Arachidonic Acid
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Area Under Curve
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Blood Platelets
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Citrates
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Citric Acid
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Collagen
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Hematocrit
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Hirudins
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Humans
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Korea
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Leukocyte Count
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Male
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Platelet Aggregation Inhibitors
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Platelet Function Tests
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Receptors, Thrombin
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Sodium
6.An Analysis of Nursing Research on Diabetes Published in Korea from 1981 to 2000.
Journal of Korean Academy of Fundamental Nursing 2001;8(3):416-429
The purpose of this study was to analyze research trends and to suggest future directions for nursing research on the diabetes in Korea. The method was a review of 97 nursing research papers on diabetes published between 1981 and 2000. Analysis included year of publication, academic theses or not, research design, key words and the results. The results of the analysis can be summarized as follows: The number of the nursing research papers on diabetes has been increasing. Of those paper analyzed, it was found that 64 (65.97%) were master's theses, and 58 (59.79%) were descriptive or correlational studies. The most frequent key word was client behavior. Client behavior as the dependent variable was reported to be influenced by various causal variables but the results were not consistent. Nursing interventions reported as effective included education, exercise therapy, camps, and telephone coaching. CONCLUSION: We question whether the concepts, measurement scales, and theories used in these research papers were appropriate for Korean clients with diabetes. Development of concepts and theories for Korean clients is necessary.
Diabetes Mellitus
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Education
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Exercise Therapy
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Korea*
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Nursing Research*
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Nursing*
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Publications
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Research Design
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Telephone
;
Weights and Measures
7.Comparing Clinical Usefulness of Cognitive Function Tests (CDT, K-MMSE, K-3MS, CDR) in Dementia Patient.
Hong Hyun SHIN ; Heeyoung SO ; Ae Young LEE
Korean Journal of Rehabilitation Nursing 2008;11(2):90-98
PURPOSE: The purpose of this study was to examine the cognitive function and degree of dementia patient by doing clock drawing test and to explore the relationship among other dementia screening test. METHOD: The study subjects were 94 dementia in patients department. The data was collected by face to face interview by clinical psychologist from January 2007 to February 2008. The tools were Clock Drawing Test, K-MMSE, K-3MS and CDR Scale. RESULTS: 1) The average score of CDT was 5.13 (2.54), of K-MMSE was 20.53 (4.85), of K-3MS was 61.66 (16.46), and of CDR was 1.2 (.72), those scores showed dementia. 2) There was a statistically the significant difference in CDT (F=2.83, p=.043) and CDR (F=2.00, p=.008) by age. CDT has shown the differences by gender (t=-2.42, p=.018) and education (F=7.66, p=.000). 3) There were significant relationships between CDT and K MMSE (r=-.294. p=.004), K-3MS (r=-.335, p=.001), and CDR (r=.286, p=.008). CONCLUSION: It is believed that using CDT which measures the visuospatial ability of dementia patients and K-MMSE which assesses an ability of language and orientation and K-3MS at the same time helps examining the beginning and the progressive degree of dementia more easily and objectively.
Cognition
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Dementia
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Deoxycytidine
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Humans
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Mass Screening
;
Orientation
8.The Effects of a Communication Program on Incivility, Critical Thinking, and Clinical Practice Stress Experienced by Nursing Students
Soon Ae KIM ; So Young LEE ; Eunhee HONG
Journal of Korean Academic Society of Nursing Education 2019;25(2):197-205
PURPOSE: To identify the effects of a communication program on nursing students' incivility, critical thinking, and clinical practice stress. METHODS: A randomized control group pretest-posttest study was conducted. Fifty randomly selected nursing students were divided into experimental and control groups. A 160-minute communication program was applied to the experimental group and a second survey was conducted two weeks later, shortly after their clinical practice. RESULTS: There was a statistically significant difference in the incivility experienced in the clinical practice after application of the communication program, and refusal in the sub-categories of incivility was statistically significant in this group. CONCLUSION: It is necessary to foster communication skills for nursing students. Communication programs reduce incivility. Therefore, nursing educators need to recognize the importance of communication during clinical practice and consider incorporating it into their regular curricula.
Curriculum
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Humans
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Nursing
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Students, Nursing
;
Thinking
9.Infestation status of Paragonimus westermani metacercariae in the second intermediate host in Ulchin county, Kyungpook Province.
Young Ae HONG ; Chong Yoon JOO ; Young Sik PYUN
The Korean Journal of Parasitology 1986;24(2):194-200
A study on the population density of crayfish intermediate hosts and infestation status of crayfish with encysted larvae of Paragonimus westermani in Ulchin county, Kyungpook province, Korea was conducted from May to October in 1986. The population density of the crayfish ranged from 1 to 13, with an average of 4 per manhour. Among the six habitats, Ducheon had a somewhat higher density than that of the others. Of eight hundred and seventeen crayfish examined, 127 or 15.5 per cent harboured the metacercarial larvae of Paragonimus westermani. The majority of the larvae were found in three parts of the body: most frequently in the cephalothorax, next in the gills, and then in the liver. The average number of metacercarial larvae per infected crayfish ranged from 1.0 to 1.9, with an average of 1.7. Summarizing the results, this study indicates that the population density of crayfish intermediate host and infestation rates for the crayfish with encysted larvae of Paragonimus westermani in Ulchin county of Kyungpook province is relatively high.
parasitology-helminth-trematoda
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Paragonimus westermani
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metacercaria
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epidemiology
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cray fish-Cambaroides similis
10.Elevated Serum C-Reactive Protein as a Prognostic Marker in Small Cell Lung Cancer.
Soojung HONG ; Young Ae KANG ; Byoung Chul CHO ; Dae Joon KIM
Yonsei Medical Journal 2012;53(1):111-117
PURPOSE: Elevated C-reactive protein (CRP) is associated with poor prognosis in several tumor types. The purpose of this study was to investigate serum CRP as a prognostic marker in small cell lung cancer (SCLC). MATERIALS AND METHODS: The pretreatment serum CRP level was measured in 157 newly diagnosed SCLC patients, and correlation between serum CRP level and other clinical parameters was analyzed. Multivariate analyses were performed to find prognostic markers using Cox's proportional hazards model. RESULTS: The initial CRP concentration was within the normal range in 72 (45.9%) patients and elevated in 85 (54.1%) patients. There was a significant correlation between serum CRP level and the extent of disease (p<0.001), weight loss (p=0.029) and chest radiation (p=0.001). Median overall survival (OS) in the normal CRp group was significantly longer than with the high CRp group (22.5 months vs. 11.2 months, p<0.001). Extent of disease (p<0.001), age (p=0.025), and performance status (p<0.001) were additional prognostic factors on univariate analysis. On multivariate analysis, elevated serum CRp level was an independent prognostic factor for poor survival (HR=1.8; p=0.014), regardless of the extent of disease (HR=3.7; p<0.001) and performance status (HR=2.2; p<0.001). CONCLUSION: High level of CRP was an independent poor prognostic serum marker in addition to previously well-known prognosticators in patients with SCLC.
Aged
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Aged, 80 and over
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Biological Markers/blood
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C-Reactive Protein/*metabolism
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Female
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Humans
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Kaplan-Meier Estimate
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Lung Neoplasms/*blood/*mortality
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Male
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Middle Aged
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Predictive Value of Tests
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Prognosis
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Small Cell Lung Carcinoma/*blood/*mortality