1.A Pathological Study of Phenol Induced Hepatic and Gastrointestinal Lesions.
Korean Journal of Pathology 1993;27(6):561-572
In an attempt to elucidate the pathological effects of phenol, the present study was undertaken in male Sprague-Dawley rats. The control group of animals was fed a basal diet, and potable underground water. The experimental group of animals was fed a basal diet and potable underground water containing 30ppm, 60ppm, and 1% phenol with once a week administration of dimethylnitrosamine(DMN) 10 mg/kg I.P. Each group of animals was sacrificed on the 3rd, 6th, and 9th month. The liver and gastrointestinal tract were examined light microscopically, along with transmission electron microscopic studies of the liver and scanning electron microscopic studies of the gastric mucosa. The results were as follows: 1) In the acute phenol intoxicated group, the liver showed fatty changes in the hepatocytes with mitochondrial membrane destruction and myelin figure formation. 2) In the chronic phenol intoxicated group, fatty changes in the liver were observed. In addition, there was chronic inflammation in the gastrointestinal tract, with gastric mucosal erosion and central necrosis of the hepatic lobules, especially in the high phenol contaminated water treated group. 3) As a result of the examination under the light microscope, the DMN treated group showed hyperplastic nodules and liver cell dysplasia, the degree of which was proportional to the duration of the experiment, and was more severe in the DMN + phenol treated group. 4) As a result of the examination under the electron microscope, fatty changes in the liver, pleomorphism of the mitochondria and loss or shortness of bile canalicular microvilli in the DMN + phenol treated group were more severe than in the group treated only with DMN. In summary, the results obtained by the present study indicate chronic highly concentrated phenol intoxication induce liver cell necrosis and chronic inflammatory with a hepatotoxin such as DMN.
Male
;
Humans
;
Animals
2.Effects of dietary fish oil on myocardical ischemia and reperfusion in isolated guinea pig heart.
Korean Circulation Journal 1993;23(1):82-91
No abstract available.
Animals
;
Cholesterol
;
Corn Oil
;
Guinea Pigs*
;
Guinea*
;
Heart*
;
Ischemia*
;
Reperfusion*
3.A Case of Localized Hypertrophic Lichen planus Treated with Triamcinolone Intralesional Injection.
Korean Journal of Dermatology 2000;38(10):1422-1424
Hypertrophic lichen planus is rare chronic variant of this disease, usually occurs on the lower extremities especially the shins, and associated with severe itching sensation. We report a case of localized hypertrophic lichen planus with bilateral hyperkeratotic polygonal violaceous papuloplaques on both upper eyelids and dorsa of hands and lace-like patches in oral mucosa. The patient had been treated with triamcinolone acetonide intralesional injection at two week intervals, two times and topical steroid after then the lesion had significantly improved.
Eyelids
;
Hand
;
Humans
;
Injections, Intralesional*
;
Lichen Planus*
;
Lichens*
;
Lower Extremity
;
Mouth Mucosa
;
Pruritus
;
Sensation
;
Triamcinolone Acetonide
;
Triamcinolone*
4.Choriocarcinoma in Kidney: A Case Report.
Korean Journal of Urology 1968;9(2):109-111
5.Management of Hypertension.
Korean Journal of Nephrology 2000;19(4):579-580
No abstract available.
Hypertension*
6.Lymph Node Ratio for Nodal Staging in Colorectal Cancer - a Promising, but Premature Tool.
Journal of the Korean Society of Coloproctology 2011;27(5):224-225
No abstract available.
Colorectal Neoplasms
;
Lymph Nodes
7.A Radiologic Approach to Diffuse Interstitial Lung Disease.
Tuberculosis and Respiratory Diseases 1997;44(4):716-728
No abstract available.
Lung Diseases, Interstitial*
8.Effect of Compound 48/80 on Cardiac Function and Histamine Release in Isolated Guinea Pig Hearts.
Korean Circulation Journal 1992;22(2):240-247
No abstract available.
Animals
;
Guinea Pigs*
;
Guinea*
;
Heart*
;
Histamine Release*
;
Histamine*
9.The effect of vitamine E on intestinal tumorigenesis by 1,2-dimethylhydrazine.
Kang Hyuk LEE ; Dae Young KANG
Journal of the Korean Cancer Association 1991;23(1):29-38
No abstract available.
1,2-Dimethylhydrazine*
;
Carcinogenesis*
;
Vitamins*
10.A case of recurrent pneumonia due to gastroesophageal reflux after repair of TEF.
Hye Young KANG ; Young Yull KOH
Pediatric Allergy and Respiratory Disease 1993;3(1):105-112
No abstract available.
Gastroesophageal Reflux*
;
Pneumonia*