No abstract available.
Korea* ; Liver Transplantation* ; Liver*

No abstract available.

No abstract available.
Free Radicals* ; Reperfusion*

Recently it has been stated that animals without ischemic arrhythmia would be at almost no risk for reperfusion ventricular fibrillation(VF) in contrast to animals with ischemic arrhythmias. In order to observe the differences of ararrhythmias characteristics between ischemic and reperfusion period, and correlationship between occlusion and reperfusion arrhythmias, the left anterior descending(LAD) coronary artery was occluded for 20 minutes and reperfused for 10 minutes in 24 anesthetized cats. The results were as follows; 1) After ligation of LAD coronary artery, the R wave, S-T segment and T wave of epicardial EKG were elevated to reach maximum level at 5-10 minutes. 2) During reperfusion, the changes of R wave, S-T segment, and T wave of epicardial EKG were not significant. 3) The incidence of arrhythmias at early phase and late phase of occlusion period were 41.6% and 100% respectively. The ischemic arrhythmia score was 2.38+/-1.61 and incidence of ventricular tachycardia(VT) was 66% 4) The incidence of VT and VF during reperfusion was 100% and 62.5% respectively. The reperfusion arrhythmia score was 5.88+/-1.72. 5) The two morphologies of ventricular arrhythmias were observed at occluson and reperfusion period. 6) The disparities between occlusion and reperfusion arrhythmias were observed. 7) The cats with shorter R-R internal and/or lower systolic left ventricualr pressure had the higher incidence of VF. In summary, although the morphology of occlusion ventricular arrhythmias was similar to that of reperfusion ventricular arrhythmias, the lack of correlation between reperfusion VF and ischemic arrhythmias was observed. So we suggest that further studies which provide the different mechanisms involved in occlusion and reperfusion arrhythmias were needed.
Animals ; Arrhythmias, Cardiac* ; Cats* ; Coronary Vessels ; Electrocardiography ; Incidence ; Ligation ; Reperfusion*

Clinical analysis is done on 108 meniscus injuries operated on at Kwangju Armed Forces General Hospital from 1961 to 1971, with the following results. l. All cases included in this report were military personnels aged from 19 to 35 years old 2. The lateral meniscus was more frequently injured than the medial with a ratio of 79 to 29 (8:3) and the right side knee than the left with a ratio of 60 to 48(6:5). 3. The posterior horn tears were the most common type of injuries involved in 40 cases (41%) 4. There could be found no history of definitive trauma in l7 cases.
Animals ; Arm ; Gwangju ; Horns ; Hospitals, General ; Humans ; Knee ; Menisci, Tibial ; Military Personnel ; Tears

The effect of amiodarone on reperfusion arrhthmias after release of left anterior descending coronary artery(LAD) occlusion was studied in 22 anesthetized cats. All cats underwent 20 minutes LAD occlusion followed by reperfusion and amiodarone(20mg/Kg) or normal saline was given on cats which had reperfusion arrhythmias through the left ventricular catheter to observe the antiarrhythmic effect of amiodarone. And also the incidence and type of arrhymias during occlusion and reperfusion were analyzed. During the 20 minute LAD occlusion, 10 of 22 cats(45%) had no arrhythmias, and 12 cats(55%) had nonsustatined ventricular tachycardia. After release of occlusion, 5 of 22 cats(23%) had no arrthmias, and 17 cats(77%) developed sustained ventricular arrhythmias(ventricular tachycardia (n=5), ventricular fibrillation(n=12)). The 17 cats which had reperfusion arrhythmias were randomly divided and given normal saline(control(n=8)) or amiodarone(amiodarone group(n=9)). There was no difference on 2 groups. The reperfusion arrhythmias disappeared in 6 out of 9 cats(66.7%) vs none of 8 controls(P<0.01). We conclude that amiodarone seems to be the effective antiarrhythmic drug on reperfusion arrhythmias after release of LAD occlusion in anesthetized cats, and might be useful for the treatment of reperfusion arrhythmias in human.
Amiodarone* ; Animals ; Arrhythmias, Cardiac* ; Catheters ; Cats ; Humans ; Incidence ; Reperfusion* ; Tachycardia ; Tachycardia, Ventricular

Vascular tissue presumed to be the most sensitive target tissue of the immune and toxic reactions. Most of the vasculitides can be directly or indirectly associated with immunopathogenic rnechanisms. In this regards, the purpose of the study is to understand imrnunopathogenic mechanism of various cutaneous vasculitides by comparing their immunopathologic patterns. Imrnunopathologic studies were carried out on the blood vessel of various skin diseases by means of the direct immunofluorescent technique using FITC conjugated rabbit antihurnan IgG, IgA, IgM, C3 C1q, C4 and fibrinogen)(F). The results obtained were as follows : 16 patients with leukocytoclastic vasculitis out of 19 showed deposition of irnmune complex in the small upper dermal vessels and had positive reaction for F, 8 for IgA, 5 for C3 and 2 for IgM. Of the 6 patients with chronic pigmented purpura studied, 2 had IgM, 3 had Ca and all of these had F in small upper or middle dermal vessels. Immunopathologic patterns of livedo vasculitis were similar to those of chronic pigmented purpurs, except mainly affected in upper dermis. Nodular vasculitis and Behqets syndrome had deposits of F, C and IgM in medium or large vessels of the middle or lower dermis. Simultaneously, Cs in 2 patients with nodular vnsculitis and IgM in one patient with Behqets syndrorne were also noted along the basement mernbrane zone. In a patient with pityriasis lichenoides et varioliformis acuta, IgM and F were noted on the samll upper dermal vessels. With these results, the immune complex mechanism could be closly related the pathogenesis of most of cutaneous vasculitis. And various clinical manifestations or expression of vasculitis appear to be dependent upon 1) type of imrnune reaction, 2) size of blood vessels, 3) location and depth of blood vessels, 4) extend of affected areas and 5) involvement of other organs.
Antigen-Antibody Complex ; Blood Vessels ; Dermis ; Fluorescein-5-isothiocyanate ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Pityriasis Lichenoides ; Purpura ; Skin Diseases ; Vasculitis*

In an attempt to find out the effect of epidural administration with morphine on postoperative pain relief, a small dose of morphine with a local anesthetic(lidocaine) was administered into the epidural space, either by lumbar or caudal approach. Morphine injected into the epidural space has been suggested to produce it's effect by direct action on the specific oplate receptor in the substantia gelatinosa of the posterior horn of the spinal cord. 90 patients who were anesthetized under epidural block in the Pusan Paik's Hospital, INJE Medical College, from May 1980 trhough Jan. 1981 were divided into the groups "Lidocaine alone" and "Lidocaine + Morphine". The number of patients of patients of the lumbar approach was 73 (81.1%) and of the caudal approach was 17(18.9%). The group "Lidocaine alone" numbered 45 cases which were injected with 2% lidocaine into the epidural space as an anesthetic. Group "Lidocaine + Morphine" also numbered 45 cases and received 2mg of morphine with 500 mg of 2% lidocaine as an epidural anesthetic. 0.2mg of 0.1% epinephrine was mixed to the anesthetic solution in all the above cases. The results of this study are as follows: 1) Alteration of arterial blood pressure during anesthesia was minimal within 30 minutes after injection of the epidural anesthetic in both groups. 2) Duration of postoperative pain relief in the group "Lidocaine + Morphine" was significantly extended comparing it to that in the group "Lidocaine alone". 3) Between the two groups, no significant difference was noted in recovery of spontaneous volding. 4) Complications were similar in both groups except for nausea and vomiting which occurred more frequently in the group "Lidocaine + Morphine"(8.9% and 6.7%, respectively) than in the group "Lidocaine alone" (2.2% and none, respectively). Any signs of CNS depression or neurologic sequelae were not observed.
Anesthesia ; Anesthesia, Epidural* ; Animals ; Arterial Pressure ; Busan ; Depression ; Epidural Space ; Epinephrine ; Horns ; Humans ; Lidocaine ; Morphine* ; Nausea ; Pain, Postoperative* ; Spinal Cord ; Substantia Gelatinosa ; Vomiting

We present here a brief literature review and a case study of postpartum pulmonary arterial hypertension, a rare and progressive disease with a high maternal mortality rate. The patient, a 32-year-old woman, presented with dyspnea and shivering immediately following an uncomplicated vaginal delivery. The patient had no remarkable individual or familial history. She died 4 hours after her delivery, and an autopsy revealed atherosclerosis of the main pulmonary arteries and characteristic plexiform lesions on the lung. The remaining organs showed no remarkable pathology. We reported pulmonary arterial hypertension associated with pregnancy as the cause of death.
Adult ; Atherosclerosis ; Autopsy ; Cause of Death ; Death, Sudden ; Dyspnea ; Female ; Humans ; Hypertension* ; Lung ; Maternal Mortality ; Pathology ; Postpartum Period* ; Pregnancy ; Pulmonary Artery ; Shivering

No abstract available.