1.Morphological study on the development of human fetal kidney.
Hee Young SHIN ; Kwang Wook KO ; Je Geun CHI
Journal of the Korean Pediatric Society 1991;34(8):1045-1056
No abstract available.
Embryonic Structures
;
Fetus
;
Humans*
;
Kidney*
2.Outbreak of Imipenemase-1-Producing Carbapenem-Resistant Klebsiella pneumoniae in an Intensive Care Unit.
Jin Young LEE ; Ji Young PARK ; Je Hun KIM ; Young Hee LEE ; Hee Young YANG ; Jung Sik YOO
Korean Journal of Critical Care Medicine 2017;32(1):29-38
BACKGROUND: Carbapenem-resistant Enterobacteriaceae (CRE) with acquired metallo β-lactamase (MBL) resistance have been increasingly reported worldwide and associated with significant mortality and morbidity. Here, an outbreak of genetically related strains of Klebsiella pneumoniae producing the imipenemase (IMP)-1 MBL in a medical intensive care unit (MICU) in Korea is reported. METHODS: Since isolating carbapenem-resistant K. pneumoniae (CRKP) at the MICU of the hospital on August 10, 2011, surveillance cultures for CRE in 31 hospitalized patients were performed from August to September 2011. Carbapenem resistance was determined based on the disk diffusion method outlined in the Clinical and Laboratory Standards Institute guidelines. Polymerase chain reaction (PCR) was performed for genes coding for β-lactamase. Associations among isolates were assessed via pulsed-field gel electrophoresis (PFGE). In addition, a surveillance study of environmental cultures and health-care workers (HCWs) was conducted in the MICU during the same time frame. RESULTS: During the study period, non-duplicated CRKP specimens were discovered in four patients in the MICU, suggestive of an outbreak. On August 10, 2011, CRKP was isolated from the sputum of a 79-year-old male patient who was admitted to the MICU. A surveillance study to detect additional CRE carriers by rectal swab revealed an additional three CRKP isolates. PCR and sequencing of the four isolates identified the presence of the IMP-1 gene. In addition, PFGE showed that the four isolated strains were genetically related. CRE was not identified in specimens taken from the hands of HCWs or other environmental sources during surveillance following the outbreak. Transmission of the carbapenemase-producing Enterobacteriaceae strain was controlled by isolation of the patients and strict contact precautions. CONCLUSIONS: This study shows that rapid and systemic detection of CRE and strict infection controls are important steps in preventing nosocomial transmission.
Aged
;
Clinical Coding
;
Critical Care*
;
Diffusion
;
Disease Outbreaks
;
Drug Resistance, Bacterial
;
Electrophoresis, Gel, Pulsed-Field
;
Enterobacteriaceae
;
Hand
;
Humans
;
Infection Control
;
Intensive Care Units*
;
Klebsiella pneumoniae*
;
Klebsiella*
;
Korea
;
Male
;
Methods
;
Mortality
;
Pneumonia
;
Polymerase Chain Reaction
;
Sputum
3.A Case of Bart's Syndrome.
Hong Shin JEON ; Young Jin HONG ; Don Hee AHN ; Hee Jun YOO ; Je Geun CHI
Journal of the Korean Pediatric Society 1994;37(1):104-108
A female newborn had the following characteristics; a congenital localized absence of skin over the lower extremities; blistering of the skin or mucous membrane, incited by trauma, which heals without scarring; and congenital absence or deformity of the nails. In respect to the characteristic manifestation, clinical course and electron microscopic features, our patient seems to fit well into Bart's syndrome. The inheritance pattern appears to be autosomal dominant but, as in this report, isolated cases have been recognized. As the review of the literatures, congenital localized absence of skin has been observed in various subsets of inherited E.B. But, we believe that the term Bart's syndrome should be used to identify patients with good prognosis as the Bart's initial description To the best of our knowedge, this is the first reported case of Bart's syndrome in the korean literature.
Blister
;
Cicatrix
;
Congenital Abnormalities
;
Female
;
Humans
;
Infant, Newborn
;
Inheritance Patterns
;
Lower Extremity
;
Mucous Membrane
;
Prognosis
;
Skin
4.Pseudolymphoma Induced by Ear Piercing.
Chang Hun HUH ; Je Young PARK ; Chong Hyun WON ; Hee Chul EUN ; Sang Eun MOON
Annals of Dermatology 2004;16(1):9-12
We present a patient who developed a pseudolymphoma after ear piercing. A patch test showed gold sensitivity. Therefore, long standing dermal exposure to gold from a pierced-type earring might have produced the patient's disease. This patient did not respond to an intralesional steroid injection and was finally treated with a complete resection of the lesion. It is proposed that every patient with a hyperplastic lesion in the ear lobe should be taken a biopsy in order to rule out the possibility of a pseudolymphoma. When a pseudolymphoma develops in the ear lobe, a complete surgical excision could be the treatment of choice, especially for the prevention of recurrence.
Biopsy
;
Body Piercing*
;
Ear*
;
Humans
;
Patch Tests
;
Pseudolymphoma*
;
Recurrence
5.A Case of Advanced Gastric Cancer, Developed from Endoscopic Diagnosis of Early Gastric Cancer.
Je Young WOO ; Ki Ho SONG ; In Sik CHUNG ; Hee Sik SUN ; Boo Sung KIM
Korean Journal of Gastrointestinal Endoscopy 1988;8(1):29-32
Early gastric cancer is defined carcinoma that is limited to the gastric mucosa and submucosa and that does not extend into the muscularis propria. The development and widespread use of upper gnstrointestinal endoscopy with biopsy and cytology have enhanced our ability to make early diagnosis of gastrie carcinoma. Gastric cancinoma is being diagnosed at an ealry stage aad the survival rates for these patients are significantly greater than those with advanced gastric carcinoma. These ealry lesion can be cured in over 90% of the cases. In fact, it is almost impossible to follow up cases of early gastric cancer without surgical treatment. We report a case developed advanced gastric carcinoma 34 months after initial endoseopic diagnosis of early gastric cancer. A, 48-year-old woman was diagnosed early gaatrie cancer on June 21, 1985 by endoscopy. Proper surgical intetvention was not carried out due to her liver cirrhosis. The follow-up endoscopic examination was done on March 16, 1988. The gastric cancer looked like an advanced stomach and extended to other site.
Biopsy
;
Diagnosis*
;
Early Diagnosis
;
Endoscopy
;
Female
;
Follow-Up Studies
;
Gastric Mucosa
;
Humans
;
Liver Cirrhosis
;
Middle Aged
;
Stomach
;
Stomach Neoplasms*
;
Survival Rate
6.Therapeutic trial of PUVA therapy on a case of telangiectasia macularis eruptiva perstans.
Sun Je SUNG ; Young Gon BAIK ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1991;29(5):667-671
No abstract available.
PUVA Therapy*
;
Telangiectasis*
7.Achondrogenesis Type 2: An autopsy case.
Joon Mee KIM ; Young Chae CHU ; Soo Kee MIN ; Hee Jeung CHA ; Je Geun CHI
Korean Journal of Pathology 1997;31(5):482-488
Achondrogenesis type 2 is a lethal form of congenital skeletal dysplasia characterized by severe short-limbed dwarfism, decreased vertebral ossification and normal ossification of the skull. We report an autopsy case of achondrogenesis type 2 in a female fetus terminated at 29 weeks of gestation. External morphology revealed a relatively large head, short upper and lower extremities, short neck, and distended abdomen. The x-ray finding showed normal calvarial ossification, hypoplastic ilium and unossified ischium, and metaphyseal flares of the femur and tibia. Histologically, chondrocytes were large and irregular with increased vascularity.
Abdomen
;
Autopsy*
;
Chondrocytes
;
Dwarfism
;
Female
;
Femur
;
Fetus
;
Head
;
Humans
;
Ilium
;
Ischium
;
Lower Extremity
;
Neck
;
Pregnancy
;
Skull
;
Tibia
8.A case of agenesis of the right lung with H-type tracheoesophageal fistula.
Yong Seok CHOI ; Kyung Hee KIM ; Young Chul AHN ; Baik Lin EUN ; Kwang Je BAEK
Journal of the Korean Pediatric Society 1992;35(6):816-821
No abstract available.
Lung*
;
Tracheoesophageal Fistula*
9.A Case of Ovarian Mucinous Cystadenocarcinoma with Mural Nodule of Anaplastic Carcinoma.
Mee Sook ROH ; Sook Hee HONG ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(3):243-247
Mural nodules in ovarian mucinous tumors, whether benign, borderline, or malignant, have been described by several authors since Prat and Scully first described sarcoma or sarcoma-like mural nodules occurring in association with mucinous epithelial neoplasia in 1979. Three distinct types of the mural nodule have been identified; i. e., 1) sarcoma-like lesion, 2) true mesenchymal sarcome, and 3) anaplastic carcinoma simulating a sarcoma. Mural nodules of sarcomatous and carcinomatous foci associated with mucinous ovarian tumors should be separated from sarcoma-like nodules because of the poor prognosis of the former compared to the favorable prognosis of the latter. We experienced a case of ovarian mucinous cystadenocarcinoma with sarcoma-appearing mural nodule of anaplastic carcinoma occurred in a 59-year-old woman and reported with brief review of the literatures.
Carcinoma*
;
Cystadenocarcinoma, Mucinous*
;
Female
;
Humans
;
Middle Aged
;
Mucins*
;
Ovary
;
Prognosis
;
Sarcoma
10.A Case of Severe Air Leak Syndrome Treated with High - Frequency Oscillatory Ventilation ( HFOV ).
Seong Hee SHIN ; Je Woo KIM ; Phil Soo OH ; Young Ah LEE ; Hye Sun YOON
Journal of the Korean Society of Neonatology 1999;6(1):121-126
In air leak syndrome, a significant portion of the volume delivered during a positive pressure breath can be lost through the leak. HFOV can achieve adequate ventilation at lower peak and/or mean intrapulmonary pressure than conventional mechanical ventilation (CMV) and has been an effective treatment of already established air leak syndrome. We report a 1-day-old male infant with severe respiratory failure from pneumothorax and pneumomediastinum, who was refractory to CMV with chest tube drainage. HFOV was applied to this patient for 114 hours, and improvement of oxygenation and ventilation as well as significant reduction of pneumothorax followed.
Chest Tubes
;
Drainage
;
Humans
;
Infant
;
Male
;
Mediastinal Emphysema
;
Oxygen
;
Pneumothorax
;
Respiration, Artificial
;
Respiratory Insufficiency
;
Ventilation*