1.A Clinical Study on BCG Lymphadenitis.
Jin Soo HWANG ; Young Youn CHOI ; Jae Sook MA ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1997;40(5):614-619
PURPOSE: We studied the incidence and clinical course of BCG lymphadenitis to investigate the BCG related problem. SUBJECT AND METHODS: Three hundred and eighty-six infants received BCG vaccine (Pasteur-1173p2) in the Well Baby Clinic, Dept. of Pediatrics, Chonnam University Hospital from May 1993 and April 1994. Among them, twenty three infants developed regional lymphadenitis. We investigated the clinical course in twenty six infants with BCG lymphadenitis (three infants were transferred from the Public Health Center and they also had taken same BCG preparations). According to the lymph node size, we divided them into three groups (A : below 1cm, 5 infants; B : 1 to 2cm, 10; C : above 2cm, 11), and evaluated the clinical outcome. RESULTS: 1) The incidence of BCG lymphadenitis was 6.0% (23/386), the differences according to sex or age at vaccination were not observed. 2) Twenty three of twenty six infants (88.5%) showed one lymph node (left axillary 19 infants, left cervical 3 infants, left supraclaviclar 1 infant), but three (11.5%) showed multiple lymph node involvement. 3) Eight (30.8%) showed spontaneous improvement, but eighteen (69.2%) received single or double antituberculous medication at the beginning or after a period of observation. Two infants were treated by incision and drainage. CONCLUSIONS: The incidence of BCG lymphadenitis was relatively higher (6.0%) than previous reports, and the two thirds of the cases received antituberculous medication and or surgical treatment. Further prospective study according to the recent recommendation by the Korean Health Administration should be needed.
BCG Vaccine
;
Drainage
;
Humans
;
Incidence
;
Infant
;
Jeollanam-do
;
Lymph Nodes
;
Lymphadenitis*
;
Lymphatic Diseases
;
Mycobacterium bovis*
;
Pediatrics
;
Public Health
;
Vaccination
2.Atypically Large Calcific Tendinitis of the Shoulder: A Case Report.
Jin Wan KIM ; Kyu Pill MOON ; Kyung Taek KIM ; Youn Soo HWANG ; Won Seok PARK
Clinics in Shoulder and Elbow 2016;19(4):241-244
Calcific tendinitis of the shoulder joint is common disease causing acute pain, mainly involving the supraspinatus or infraspinatus muscle, and less frequently the teres minor or subscapularis muscle. This study reports on the satisfactory arthroscopic removal of calcium deposits as well as infraspinatus and supraspinatus muscle repair without relapse via minimal incision using suture anchors. This was a case of atypically extensive calcific tendinitis involving the infraspinatus muscle, with a bursal side partial rupture of the supraspinatus muscle in a 61-year-old female whose chief complaint was chronic pain of the right shoulder exacerbated by limited movement.
Acute Pain
;
Calcium
;
Chronic Pain
;
Female
;
Humans
;
Middle Aged
;
Recurrence
;
Rupture
;
Shoulder Joint
;
Shoulder*
;
Suture Anchors
;
Tendinopathy*
3.Ossification of the Coracoacromial Ligament in Subacromial Impingement Syndrome: A Case Report.
Kyupill MOON ; Youn Soo HWANG ; Kyung Taek KIM ; Jin Wan KIM ; Jeong Hoon CHAE
Clinics in Shoulder and Elbow 2017;20(3):167-171
Here, a case of a 59-year-old man with rotator cuff tear and impingement syndrome caused by an ossified coracoacromial ligament is presented. Ossification of the coracoacromial ligaments can occur because of degenerative changes due to trauma or repeated stress, which can lead to impingement syndrome. Therefore, when coracoacromial ligament ossification is present, rotator cuff damage due to impingement syndrome should be considered. Here, we conducted arthroscopic subacromial decompression, removal of the ossified coracoacromial ligament, and supraspinatus and subscapularis tendon repairs. We achieved satisfactory surgical outcomes without relapse; therefore, we report this case with a literature review.
Decompression
;
Humans
;
Ligaments*
;
Middle Aged
;
Recurrence
;
Rotator Cuff
;
Shoulder
;
Shoulder Impingement Syndrome*
;
Tears
;
Tendons
4.Pregnancy following conization of the cervix.
Yoon Young LEE ; Soo Hyun CHO ; Sam Hyun CHO ; Youn Yeoung HWANG ; Jai Auk LEE
Korean Journal of Obstetrics and Gynecology 1993;36(5):614-617
No abstract available.
Cervix Uteri*
;
Conization*
;
Female
;
Pregnancy*
5.Adolescent menstrual disorders: Comparison Between 1988 and 1998.
Soo Hyun CHO ; Kee Don KIM ; Seung Ryong KIM ; Sam Hyun CHO ; Youn Yeung HWANG
Korean Journal of Obstetrics and Gynecology 1999;42(9):2043-2047
OBJECTIVE: To compare the age of menarche, changing patterns of the menstrual characteristics in adolescent girls between 1988 and 1998. METHODS: A survey was undertaken for 1,500 highschool girls and compare with those of pervious study for 5,000 middle and highschool girls performed by same author in 1998 by means of questionnaire. RESULTS: During a decade, the mean menarcheal age decreased from 13.5+/-1.0 to 12.7+/-1.0 years(p=0.001). Gynecologic age, Body mass index were associated with age of menarche in both 1988 and 1998. The interval of menstruation was 30.6 3.5dyas in 1998 and shortened compared with 32.1+/-6.3 days in 1988(p=0.001). The duration of menstruation was lengthened in 1998 than in 1988(6.1+/-1.1 days vs 5.8+/-2.2 days, p=0.001). The incidence of irregular cycle(28.2% vs 58.2%, p=0.001), dysmenorrhea(73.9% vs 77.8%, p=0.001), and secondary amenorrhea(16.2% vs 27.2%, p= 0.001) decreased in 1998 compared with those of 1988. The incidence of agonies about menstruation was also decreased in 1998 than in 1988(26.2% vs 69.1%, p=0.001). The most common agony about menstruation in 1988 was irregular cycle(28.4%), but dysmenorrhea( 64.3%) in 1998. CONCLUSIONS: From the above results, the mean age of menarche was advanced since last decade but most of the adolescent girls still have suffered from dysmenorrhea.
Adolescent*
;
Body Mass Index
;
Dysmenorrhea
;
Female
;
Humans
;
Incidence
;
Menarche
;
Menstruation
;
Surveys and Questionnaire
6.Three cases of Lyphodystophia Centrifugalis Abdominalis Juvenilis.
Young Soo CHUN ; Byung Hee KIM ; Young Youn CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1990;33(8):1146-1152
No abstract available.
7.A case of Beckwith-Wiedemann Syndrome.
Jin Soo CHOI ; Byung Hee KIM ; Young Soo CHON ; Hwa Il KWANG ; Young Youn CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1990;33(3):367-372
No abstract available.
Beckwith-Wiedemann Syndrome*
8.Generation and maintenance of type II collagen-specific T-cell line expressing conserved TCR-CDR3 motifs among patients with rheumatoid arthritis Author.
Seung Hoon KIM ; Mi La CHO ; Jee Hee YOUN ; Sung Hwan PARK ; Sue Yun HWANG ; Ho Youn KIM ; Chul Soo CHO
Immune Network 2001;1(1):61-69
BACKGROUND: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). METHODS: We generated CII-specific T-cell lines of 8 RA patient s by prolonged in vitro culture with bovine CII (bCII) and the immunogenic peptide (256-270) of human CII. The proliferation response towards CII stimulation was measured from the uptake of 3 H-thymidine. Changes in the secretion of Th 1 and Th2 cytokines in the culture supernatent were measured by ELISA. The TCR clonotypes of these T-cells were examined by RT-PCR/ SSCP analyses of all 22 V beta chains. RESULTS: T-cells from patients' tissue exhibited strong proliferation index upon CII stimulation, which was maintained up to 6 months in the culture. The secretion of INF-gamma from these T-cells increased along with the duration of culture time, while the amount of IL-4 production did not show significant changes. The SSCP band patterns of patients' T-cells appear as discrete bands unlike the smeary streak produced from normal samples. Some SSCP bands, each representing selected expansion of a TCR containing certain subtype of V beta peptides, appeared to be identical in more than one patients. Among these, the expansion of SSCP band representing the V beta 14 CDR3 region persisted after switching the antigen to the immunogenic human peptide (256-270). CONCLUSION: CII-reactive T-cells expressing distinct CDR3 motifs are selectively expanded in the peripheral blood and synovial fluid of RA patients, and their persistent proliferation upon CII stimulation, as well as the production Th 1-type cytokines, may play pivotal roles in RA pathogenesis.
Arthritis, Rheumatoid*
;
Cytokines
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Interleukin-4
;
Molecular Structure
;
Peptides
;
Polymorphism, Single-Stranded Conformational
;
Receptors, Antigen, T-Cell
;
Synovial Fluid
;
T-Lymphocytes*
9.Purturbation of Th1 / Th2 Balance by Interleukin 4 Receptor alpha Variant Q576R in Rheumatic Disease.
Sung Hee HWANG ; Jee Hee YOUN ; Chul Soo CHO ; Jun Ki MIN ; Wan Uk KIM ; Sung Hwan PARK ; Ho Youn KIM
Korean Journal of Immunology 2000;22(1):9-15
No abstract available.
Interleukin-4*
;
Interleukins*
;
Receptors, Interleukin-4*
;
Rheumatic Diseases*
10.Nutritional status and plasma amino acid profile in maintenance hemodialysis patients.
Dong Jin YOUN ; Jin Kook KIM ; Soo Jeong CHOI ; Tae Youn CHOI ; Seung Duk HWANG
Korean Journal of Medicine 2002;62(5):522-529
BACKGROUND: Many studies document the presence of abnormalities in amino acids metabolism in chronic uremia. These abnormalities have been attributed to low protein intake, deficiency of excretory and metabolic functions of the diseased kidneys, toxic effects of uremia on the intermediary metabolism of amino acids and in dialysis patients, loss of protein and amino acids by the dialytic procedure. METHODS: This study was designed to compare anthropometric measurement, biochemical characteristics and plasma amino acid concentration between patients with end stage renal disease on maintenance hemodialysis (HD) and normal controls. A cross sectional study of overnight fasting plasma amino acids and plasma albumin, prealbumin, triglyceride (TG), cholesterol, transferrin concentration were performed on 20 hemodialysis patients and 20 normal controls, matched by age and sex. RESULTS: The concentrations of prealbumin (25.60+/-7.05 mg/dL vs 35.08+/-8.11 mg/dL, p<0.005), transferrin (158.30+/-39.66 mg/dL vs 275.50+/-55.46 mg/dL, p<0.001) were found to be lower in HD patients. No differences in albumin, cholesterol and TG were observed between the two groups. Several amino acids (taurine, cystine, phosphoserine) were found to be higher in the HD patients, while the concentrations of other five amino acids (serine, alanine, valine, leucine, tyrosine) were lowered in HD patients. No differences in nine amino acids (asparagine, glutamine, proline, glycine, methionine, isoleucine, lysine, histidine, arginine) were observed between the two groups. CONCLUSION: Our results suggest that chronic renal failure patients have malnutrition and amino acids abnormalities. To correct the amino acids abnormalities and improve nitrogen utilization in hemodialysis patients, correction of acidosis and supplementation of the diet with serine should be considered.
Acidosis
;
Alanine
;
Amino Acids
;
Cholesterol
;
Cystine
;
Dialysis
;
Diet
;
Fasting
;
Glutamine
;
Glycine
;
Histidine
;
Humans
;
Isoleucine
;
Kidney
;
Kidney Failure, Chronic
;
Leucine
;
Lysine
;
Malnutrition
;
Metabolism
;
Methionine
;
Nitrogen
;
Nutritional Status*
;
Plasma*
;
Prealbumin
;
Proline
;
Renal Dialysis*
;
Serine
;
Serum Albumin
;
Transferrin
;
Triglycerides
;
Uremia
;
Valine