1.A Case of Scrotal Cancer.
Cheol Heon LEE ; Jai Il YOUN ; Hong Sik KIM
Korean Journal of Dermatology 1976;14(3):221-225
We presented a case of non-occupational scrotal cancer in 66-year-old male. He was a farmer and did not contact with any known carcinogen on past history. He had several erythematous walnut-sized nodules on scrotum and diffuse oozing erythema on penoscrotal and hoth crural areas. And his sclera was icteric and liver was palpable to the 3-flnger-breadth from the costal margin and had hard consistency and nodular surface. Spleen was palpable to the 4-finger-breadth. On laboratorary exarninations marked liver furtction impairment was noted. On histologic examinations of biopsied scrotal skin and ingoiaal lymyhnode undifferentiated squamous cell carcinoma was noted. On the 5th day of admission he became dull and irritable and tbe condition was deteriorated from day to day. At that time blood ammonia level was elevated to 140.63mcg% He was discharged in comatose state without any treatrnent for the scrotal cancer itself and died 4 days later.
Aged
;
Ammonia
;
Carcinoma, Squamous Cell
;
Coma
;
Erythema
;
Humans
;
Liver
;
Male
;
Sclera
;
Scrotum
;
Skin
;
Spleen
2.The Study of Identification of Methicillin-Resistant Staphylococcus Aureus using Polymerase Chain Reaction.
Youn Gyoung GIL ; Jin Hong JEONG ; Chan Bin IHM ; Youn Sik SHIN ; Sun Hoe KOO
Korean Journal of Clinical Pathology 1997;17(4):581-587
BACKGROUND: Rapid and accurate identification of methicillin-resistant Staphylococcus (MRSA) is very important for patients because they are one of the most common etiologic agents of hospital infection. Conventional identification methods for MRSA are influenced by various factors such as pH, concentration of salt, conditions of media. METHODS: 53 methicillin resistant staphylococcus strains identified by ATB plus system (Biomerieux, France) were preformed the polymerase chain reaction (PCR), Southern blot hybridization fort the detection of mec A gene, and subcultured in Meuller-Hinton media containing 4 microgram/mL oxacillin for the comparison. RESULTS: The correlation of detection rate of mec A gene PCR and ATB plus systems was 81.6%. The correlation of mec A gene PCR and MRSA on Mueller-Hinton media containing 4 microgram/mL oxacillin was 80%. We confirmed by Southern blot hybridization the amplified mer A gene originated from chromosome of MRSA. As the results of oxacillin sensitivity test, minimal inhibitory concentrations of MRSA were distributed between 40 microgram/mL and 320 microgram/mL. When compared with executing time, ATB plus system took 24 hours, but PCR took 5 hours for identification. CONCLUSION: We concluded that mec A gone PCR techniques were simple and rapid for detection of MRSA comparative to conventional methods.
Blotting, Southern
;
Cross Infection
;
Genes, vif
;
Humans
;
Hydrogen-Ion Concentration
;
Methicillin Resistance*
;
Methicillin-Resistant Staphylococcus aureus*
;
Oxacillin
;
Polymerase Chain Reaction*
;
Staphylococcus
3.One Case of Erythromelalgia.
Jai Il YOUN ; Cheol Heon LEE ; Hong Sik KIM ; Choong Sang KIM
Korean Journal of Dermatology 1976;14(1):63-67
Erythromelalgia is a rare disease characterized by burning pain of the extremities associated with erythema and increased temperature of the skin. A case of erythromelalgia was reported with review of literatures. It seemed that this is the first reported case in Korean literatures. patient was 12 years old male having erythematous swelling associated with burning pain on his feet and lower legs for five years. Immersion of his feet in warm water quickly, increased the pain but cold water gave prompt relief that he soaked his feet for many hours during the day and night. No specific abnormalities were noticed in Iaboratory studies, Treatment with various topical, systemic medication revealed of unfavorable result.
Burns
;
Child
;
Erythema
;
Erythromelalgia*
;
Extremities
;
Foot
;
Humans
;
Immersion
;
Leg
;
Male
;
Rare Diseases
;
Skin
;
Water
4.Ultrasonographic findings of pelvic masses
Youn Jin KIM ; In Soo HONG ; Hyung Sik YOO ; Chang Yun PARK
Journal of the Korean Radiological Society 1982;18(3):610-617
Ultrasonography affords an accurate assessment of the presence, size, location and internal consistency of apelvic mass. We present our experience of 105 cases of pelvic masses in female patients by ultrasonography, andthe results are as described; 1. Ultrasonography is nonspecific, however, the possibility of mucinous cystadenomaof ovary, teratoma(dermoid cyst), uterine leiomyoma and trophoblastic disease can be suggested due to theircharacteristic internal consistency. 2. This smooth internal septation seen within mucinous cystadenoma, eccentricsolidmural component of dermoid cyst, enlarged uterine wall with lobulated outer margin of leiomyoma, andyesicular appearance of trophoblastic disease were the specific sonographic features. 3. Loculated ascites and hydronephrosis were identified with malignant ovarian neoplasm and pelvic metastasis. 4. Accurate ultrasonographicdiagnosis was made in 88 cases (83.7%) and it may be improved with clinical history of the mass in question.
Ascites
;
Cystadenoma, Mucinous
;
Dermoid Cyst
;
Female
;
Humans
;
Hydronephrosis
;
Leiomyoma
;
Mucins
;
Neoplasm Metastasis
;
Ovarian Neoplasms
;
Ovary
;
Trophoblasts
;
Ultrasonography
5.Two cases of renal vein thrombosis in patients with systemic lupus erythematosus.
Sang Heon LEE ; Young Shin SHIN ; Ji Youn HAN ; Jae Kyung CHOI ; Seung Hun LEE ; Youn Sik HONG ; Chul Soo CHO ; Dong Jun PARK ; Ho Youn KIM
Korean Journal of Medicine 1993;45(3):376-382
No abstract available.
Humans
;
Lupus Erythematosus, Systemic*
;
Renal Veins*
;
Thrombosis*
6.A Case of Left Main Coronary Artery Disease Treated with Medication.
Geon Young KIM ; Geung Sik JANG ; Sun Pyuo HONG ; Sang Jun YOUN ; Young Kon KIM ; Hee Jong KIM
Korean Circulation Journal 1999;29(4):415-418
We report a case of 34-year-old woman who had left main coronary artery disease and treated with medication only. She was presented with severe chest pain. Isolated left main coronary disease was demonstrated on selective left coronary angiography. There was no regional wall motion abnormality on echocardiogram with normal global LV systolic function. We considered the lesion as a varient of Takayasu's arteritis. So with anti-anginal medication, treatment started with steroid therapy. After then there was no chest pain. We performed follow-up coronary angiography after 1 month and 3 month in which revealed improved left main lesion. Since then there was no subjective symptom and Thallium-201 SPECT revealed no significant ischemic finding. We think that this case's underlying disease is may be Takayasu's arteritis which has isolated left main stenosis without systemic involvement and improved with medical treatement only.
Adult
;
Chest Pain
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Disease
;
Coronary Vessels*
;
Female
;
Follow-Up Studies
;
Humans
;
Takayasu Arteritis
;
Tomography, Emission-Computed, Single-Photon
7.The analysis of the emergency patients: for the training of emergency medicine residents.
Kwang Je BAEK ; Seung Hoi PARK ; Kyung SUN ; Youn Hee CHANG ; Byung Sun UM ; Yun Sik HONG
Journal of the Korean Society of Emergency Medicine 1993;4(2):138-147
No abstract available.
Emergencies*
;
Emergency Medicine*
;
Humans
8.Surgical Outcome of Patients with Ischemic Cardiomyopathy Selected by the Results of Myocardial Viability by Preoperative F-18 FDG PET.
Jae Sung KIM ; Dong Soo LEE ; Suk Keun HONG ; Young Tak LEE ; Yu Kyeong KIM ; Youn Jung KIM ; Keon Sik MOON ; Tae Kyoung WON ; Hweung Kon HWANG
Korean Journal of Nuclear Medicine 2000;34(4):276-284
PURPOSE: We investigated the operative outcome after bypass surgery in patients selected using viability criteria on F-18 FDG PET. MATERALS AND METHODS: Rest-24hr delay redistribution imaging of Tl-201 SPECT and F-18 FDG PET were performed in 11 patients. Seven of these 11 patients (6 men, 1 woman) were evaluated to have viable myocardium by F-18 FDG PET. Changes in symptoms and left ventricular ejection fraction (LVEF) after operation were evaluated. RESULTS: In seven of 11 patients, a significant amount of viable myocardium was found on F-18 FDG PET and Tl-201 SPECT. Severity of both chest pain and dyspnea improved markedly in all patients. Mean LVEF improved from 22% to 32%. CONCLUSION: F-18 FDG PET could be used to select the patients who will benefit from coronary artery bypass surgery.
Cardiomyopathies*
;
Chest Pain
;
Coronary Artery Bypass
;
Dyspnea
;
Humans
;
Male
;
Myocardium
;
Positron-Emission Tomography
;
Stroke Volume
;
Tomography, Emission-Computed, Single-Photon
9.A Case of Trigeminal Neuropathy Associated with Mixed Connective Tissue Disease.
Seok Joon SHIN ; Tak Yong KIM ; Jun Ki MIN ; Sang Heon LEE ; Yeon Sik HONG ; Sung Hwan PARK ; Jeong Lim MOON ; Chul Soo CHO ; Ho Youn KIM
The Journal of the Korean Rheumatism Association 1997;4(2):191-196
The occurrence of a trigeminal neuropathy associated with connective tissue disease is rare. Trigeminal neuropathy in connective tissue disease is predominantly sensory and it is characterized by numbness, hypesthesia, slurred speech, and touch pain. Although the pathogenesis of trigeminal neuropathy associated with connective tissue disease remains obscure, the main pathologic findings are vasculitis and neuritis. A case of trigeminal neuropathy associated with mixed connective tissue disease is described, and the incidence, symptoms, pathophysiology, treatment of the disease is discussed.
Connective Tissue Diseases
;
Hypesthesia
;
Incidence
;
Mixed Connective Tissue Disease*
;
Neuritis
;
Trigeminal Nerve Diseases*
;
Vasculitis
10.Obstetric Outcomes in Patients with Systemic Lupus Erythematosus.
Wan Uk KIM ; Jun Ki MIN ; Nak Ki KWUN ; Sung Hwan PARK ; Yeon Sik HONG ; Sang Heon LEE ; Chul Soo CHO ; Ho Youn KIM
The Journal of the Korean Rheumatism Association 1997;4(2):131-138
OBJECTIVE: To analyze the effect of clinical and serological variables of SLE on pregnancy outcome and to analyze the effects of pregnancy on the disease course of SLE. METHODS: We studied retrospectively about 91 pregnancies in 41 female patients with SLE, who had visted to Kangnam St Mary Hospital from January,1990 to May,1996. We divided the patients into two groups, who had been pregnant before SLE was established versus who were pregnant after SLE had been established. We considered the former as control group. We compared the fetal or maternal outcomes after divided the latter into subgroups according to our purposes such as cases with lupus flare versus without lupus flare, autoantibody (+) cases versus (-) cases, cases with renal disease versus without renal disease. RESULTS: The rate of fetal loss, prematurity was 19. 7%, 46. 9% respectively in 63 cases of 32 patients who were pregnant after SLE had been estabished. The number of pregnancy loss and premature delivery was higher in pregnancy after SLE was established than before SLE was established. Lupus flare was associated with the positivity of antibody to ds DNA and negativity of antibody to Ro. The frequency of fetal loss was higher in pregnancies of antiphospholipid (+) women than those of antiphospholipid (-) women. Pregnancy with renal involvement was associated with short duration of gestation and small body weight of neonate. CONCLUSION: Lupus pregnancy remains highly risky from a maternal standpoint in terms of increased lupus activity and from fetal outcome standpoint in terms of fetal loss and preterm birth, especially in the antiphosphospholid positive mother.
Antibodies, Antiphospholipid
;
Body Weight
;
DNA
;
Female
;
Humans
;
Infant, Newborn
;
Lupus Erythematosus, Systemic*
;
Mothers
;
Pregnancy
;
Pregnancy Outcome
;
Premature Birth
;
Retrospective Studies