1.Clinical Study of Conservative Management of the Acute Epidural Hematoma.
Ju Han LEE ; Seong Ho KIM ; Youn KIM
Journal of Korean Neurosurgical Society 1990;19(10-12):1323-1328
The authors present 31 patient with acute epidural hematoma who had been admitted from January, 1987 to June. 1989 managed by consevative treatment. The results were as follows ; 1) The age of patients was distributed evenly, most patients were male (26 cases) and the most common mechanism of injury was traffic accidents(14 cases). 2) Sites of hematoma were mostly the temporal and parietal area and the maximum thickness of hematoma was not different from each site. 3) On admission, all patients presented GCS score above 13 except 2 cases. 4) All patients did not undergo delayed up, due to the enlargement of the hematoma or neurological deterioration. 5) The maximum thickness of hematoma was under 20 mm in all patients. 6) The hematoma was resolved within 30 days in all cases. This was confirmed with brain CT scan.
Brain
;
Hematoma*
;
Humans
;
Male
;
Rabeprazole
;
Tomography, X-Ray Computed
2.Comparative Studies of the Effect on the Cat Brain between Intermittent Brain Retraction and Continuous Brain Retraction.
Seong Ho KIM ; Joo Han LEE ; Youn KIM
Journal of Korean Neurosurgical Society 1990;19(10-12):1405-1416
The authors compared the changes of morphology, blood brain barrier alteration, pathology, arterial blood lactate content and cerebrospinal fluid lactate content between an intermittent brain retraction group and a continuous brain retraction group in 56 mongrel cats. The results were as follows ; 1) Microscopically, hemorrhages were punctate in 15 cases among 25 cases in the intermittent retraction group. However, there were multiple or large hemorrhages in 13 cases among the 25 cases in the continuous brain retraction group. 2) All cases of the intermittent retraction group showed 0~25% Evans blue staining of the coronal section crossing the retraction site. However, 8 cases among the 25 cases of the continuous retraction group showed 51~75% Evans blue staining and 4 cases of this group showed 76~100% staining. 3) With photomicroscopy, the authors noted small hemorrhage and cellular swelling in the intermittent retraction group instead of pyknosis, hemorrhagic necrosis, vacuolation in the continuous retraction group. 4) The change of arterial blood lactate content was from 1.22+/-0.24mmol/L at preretraction time to 1.42+/-0.26mmol/L at 90 minutes after release of retractor in the intermittent retraction group(p<0.01). In the continuous retraction group, the authors noted a change in the lactate content from 1.20+/-0.38mmol/L to 3.15+/-0.97mmol/L for the same time as above(p<0.001). 5) The change of CSF lactate content in the intermittent retraction group was from 1.39+/-0.29mmol/L at preretraction time to 1.43+/-0.23mmol/L at 90 minutes after release of retractor(p>0.05). In the continuous retraction group, this author noted change in the lactate content from 1.37+/-0.28mmol/L to 2.11+/-0.52mmol/L for the same time as described above(p<0.01). From the above results, the superiority of the intermittent brain retraction was demonstrated as compared with the continuous brain retraction. Also the possible utilization of this experimental method was discussed for other wxperimental studies on ischemia.
Animals
;
Blood-Brain Barrier
;
Brain*
;
Cats*
;
Cerebrospinal Fluid
;
Evans Blue
;
Hemorrhage
;
Ischemia
;
Lactic Acid
;
Necrosis
;
Pathology
3.Finding and Characterization of Viral Nonstructural Small Protein in Prospect Hill Virus Infected Cell.
Ki Yean NAM ; Dong Hoon CHUNG ; Jae Won CHOI ; Youn Seong LEE ; Pyung Woo LEE
Journal of the Korean Society of Virology 1999;29(4):221-233
No abstract available.
4.Growth of Human Melanocytes in Human Epidermis Reconstructed by Culture.
Kwang Hyun CHO ; Dong Youn LEE ; Seong Gyu YANG ; Un Cheol YEO ; Kyoung Chan PARK ; Jai Il YOUN
Korean Journal of Dermatology 1997;35(3):526-531
BACKGROUND: Melanocytes grown in pure monolayer culure lack many of the cellular interactions that exist in vivo. This can be partially overcome by growing melanocytes together with other epidermal cells in skin equivalent models. OBJECTIVE: The objective of the present study was to grow human melanocytes in human epidermis reconstructed on dermal substrates in vitro and to examine their response to UV radiation. METHODS: The skin equivalents were prepared by seeding cultured human keratinocytes together with cultured human melanocytes(in a ratio of 5%) onto de-epidermized dermis. After 7 days of culture, they were exposed to UVB irradiation(total 150m J/cm over 5days). On day 12 of air exposure the sections of the skin equivalents were prepared for histology. The structure of the skin equivalents was studied following staining with hematoxylin and eosin. Melanocytes were characterized by DOPA staining and by immunohistochemistry. RESULTS: Melanocytes were localized singly within the basal layer of the reconstructs. Melanin was also visible both in the melanocytes and in neighboring keratinocytes. There was an increase in melanocyte size and dendricity following UV irradiation. Melanocytes became positive to staining with HMB-45 antibody following UV irradiation. CONCLUSION: Our results indicate that melanocytes grown in reconstructed human epidermis are functional and capable of responding to UV irradiation.
Dermis
;
Dihydroxyphenylalanine
;
Eosine Yellowish-(YS)
;
Epidermis*
;
Hematoxylin
;
Humans*
;
Immunohistochemistry
;
Keratinocytes
;
Melanins
;
Melanocytes*
;
Skin
5.Cerebral Arterial Embolism Treated by Intra-Arterial Infusion of Urokinase Which Was Occurred during Percutaneous Balloon Mitral Valvuloplasty.
Jae Joong KIM ; Seung Jung PARK ; Seong Wook PARK ; In Whan SEONG ; Jong Koo LEE ; Youn Mee HWANG ; Dae Cheol SEO
Korean Circulation Journal 1991;21(1):146-150
Cerebral arterial embolism which resulted in total occlusion of right proximal middle cerebral artery was occured in 33 years old female patients with severe mitral stenosis and atrial fibrillation during percutaneous mitral balloon valvuloplasty(PMV). The occluded artery could be detected by transfemoral carotid angiography and recanalized immediately by intra-arterial infusion of urokinase. There were no cerebral hemorrhage by CT scan after intra-arterial urokinase infusion and the patients discharged without any neurologic sequale 7 days after thrombolysis. We report a case of successful recanalization with intraarterial infusion of urokinase in patient with cerebral arterial embolism occurred during PMV.
Adult
;
Angiography
;
Arteries
;
Atrial Fibrillation
;
Cerebral Hemorrhage
;
Embolism*
;
Female
;
Humans
;
Infusions, Intra-Arterial*
;
Intracranial Embolism
;
Middle Cerebral Artery
;
Mitral Valve Stenosis
;
Tomography, X-Ray Computed
;
Urokinase-Type Plasminogen Activator*
6.Activities of Infection Control in Pusan Paik Hospital, Inje University.
Young Soon BEA ; Hee Kyung SEONG ; Youn Jae LEE ; Young Jae KIM
Korean Journal of Nosocomial Infection Control 1997;2(1):73-76
No abstract available.
Busan*
;
Infection Control*
7.Two Cases of Congenital TBG Deficiency.
In Seong JO ; Ha Joo CHOI ; Young Ah LEE ; Woo Gap CHUNG ; Youn Bok CHANG
Journal of the Korean Pediatric Society 1995;38(5):697-701
No abstract available.
8.A Statistical Study of Pediatric Dermatoses During Last 10 Years (1975 ~ 1984).
Yong Kee SEONG ; Seon Hoon KIM ; Hee Chul EUN ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1986;24(2):196-204
11,609 of childhood new outpatients seen in Department of Dermatology of Seoul National University Hospital from 1975 to 1984 were analyzed statistica,lly. The study results were summarized as follows: l. 11, 609 out of 48, 188 new outpatients were under 15 years old age, amounting to 24. l %. 2. The 10 most common dermatoses were atopic dermatitis, vitiligo, urticari, hemangiorna, contact dermatitis, fungal disease, molluscum contagiosum, scabies, impetigo and nevocellular neuvs. The most freguent age groups were 2 to 6 years amounting to 47 2p, af total outpatients. 4. The peak incidence occurred in August, while the lowest incidence occurred in November and October. 5. Dermatoses which showed increasing tendency were nevocellular nevus and vitiligo, those of decreasing tendency were contact dermatitis and impetigo,
Adolescent
;
Dermatitis, Atopic
;
Dermatitis, Contact
;
Dermatology
;
Humans
;
Impetigo
;
Incidence
;
Molluscum Contagiosum
;
Nevus
;
Outpatients
;
Scabies
;
Seoul
;
Skin Diseases*
;
Statistics as Topic*
;
Vitiligo
9.Two Cases of Plasma Cell Cheilitis Treated with Intralesional Injection of Corticosteroids.
Nark Kyoung RHO ; Seong Jae YOUN ; Hyung Seok PARK ; Eil Soo LEE
Annals of Dermatology 2003;15(1):34-38
Plasma cell cheilitis is a rare inflammatory disorder which shows a dense, band-like infiltrate of plasma cells in the upper dermis. Although the histological picture is shared with other diseases of the lips, plasma cell cheilitis is not associated with any known dermatoses. Some authors have shown the effectiveness of topical or intralesional corticosteroids; however, there have been many reports describing poor therapeutic response to topical steroids. We de-scribe two patients with plasma cell chielitis whose clinical condition responded rapidly to the intralesional injection of corticosteroids.
Adrenal Cortex Hormones*
;
Cheilitis*
;
Dermis
;
Humans
;
Injections, Intralesional*
;
Lip
;
Plasma Cells*
;
Plasma*
;
Skin Diseases
;
Steroids
10.The discharge patterns and the caloric response of the primary afferent vestibular neurons.
Sang Heun LEE ; Jong Joub YOUN ; Eun Kyung CHO ; Tae Hwan CHO ; Chang Sup SEONG
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):921-928
No abstract available.
Neurons*