1.Clinicopathologic analysis on 25 cases of giant cell tumor of bone.
Hyun Ki YOUN ; Seung Seok SEO ; Hyun Duk YOO ; Young Chang KIM ; Jang Seok CHOI ; Young Goo LE
The Journal of the Korean Orthopaedic Association 1993;28(6):2256-2264
No abstract available.
Giant Cell Tumor of Bone*
;
Giant Cell Tumors*
;
Giant Cells*
2.Pseudo-Meigs' syndrome associateed with pedunculated subserosal myoma and elevated CA-125 level.
Seung Hyun HONG ; Youn Seok CHOI
Korean Journal of Obstetrics and Gynecology 2005;48(12):2998-3003
Pseudo-Meigs' syndrome consists of pleural effusion, ascites, and benign tumors of the ovary other than fibromas. These benign tumors include those of the fallopian tube or uterus and mature teratomas, struma ovarii, and ovarian leiomyomas. Although uterine leiomyomas are frequent gynecological finding, they are rarely cause pseudo-Meigs' syndrome with elevated serum CA 125 levels. A case of pseudo-Meigs' syndrome associated with subserosal leiomyoma is presented with a brief review of literatures.
Ascites
;
Fallopian Tubes
;
Female
;
Fibroma
;
Hydrothorax
;
Leiomyoma
;
Myoma*
;
Ovary
;
Pleural Effusion
;
Struma Ovarii
;
Teratoma
;
Uterus
3.The Effect of Intravitreal Triamcinolone Acetonide on Intraocular Pressure.
Youn Seok IN ; Joon Hyun KIM ; Ki Bang UHM
Journal of the Korean Ophthalmological Society 2004;45(7):1075-1080
PURPOSE: To evaluate the effect of a single intravitreal injection of 4.0 mg/0.1ml triamcinolone acetonide on intraocular pressure (IOP). METHODS: Retrospective studies were conducted by reviewing the charts of 26 eyes of 24 patients that were followed up for 16 weeks after intravitreal triamcinolone injection. The IOPs before and after triamcinolone injection were measured with Goldmann applanation tonometer. RESULTS: Within 16 weeks after intravitreal triamcinolone acetonide injection, 23 of 26 eyes (88.5%) demonstrated an increment in IOP of 5 mmHg or greater, and 6 of 26 (23.1%) had an increment of 10 mmHg or greater. The mean duration of the increase in IOP of 5 mmHg or greater was 5.5 weeks (standard deviation=4.4), and the mean time to reach maximum IOP was 6.6 weeks (standard deviation=4.4). The difference between the mean pre-injection IOP (14.12 mmHg, n=26) and the maximum post-injection IOP (24.65 mmHg, n=26) was statistically significant (P<0.001). All eyes that needed treatment responded to topical glaucoma medication. CONCLUSIONS: An increment in IOP is a common complication after a single intravitreal injection of 4.0 mg/0.1ml triamcinolone acetonide and despite this serious increment in IOP, it was controlled by topical glaucoma medication.
Glaucoma
;
Humans
;
Intraocular Pressure*
;
Intravitreal Injections
;
Retrospective Studies
;
Triamcinolone Acetonide*
;
Triamcinolone*
4.Anaplastic Thyroid Carcinoma: A Therapeutic Dilemma.
Hang Seok CHANG ; Kee Hyun NAM ; Woung Youn CHUNG ; Cheong Soo PARK
Yonsei Medical Journal 2005;46(6):759-764
Anaplastic thyroid carcinoma (ATC) is one of the most malignant human neoplasms and has a grave prognosis. This study gives an update on our experience with this unusual neoplasm, with specific focus on the response to various treatment modalities. Forty-seven patients with histologically proven ATCs were enrolled (19 men, 28 women; mean age, 62.8 years). This number represents 1.5% among a total of 3, 088 thyroid cancers treated between 1977 and 2002. The mean tumor diameter was 8.8 cm, and 22 patients had distant metastasis. Extrathyroidal extension was seen in 26 (89.7%) of the cases that underwent surgery. Treatment modalities adopted could be classified into 5 groups: Group 1, biopsy only; Group 2, biopsy and chemoradiotherapy; Group 3, debulking only; Goup 4, debulking and chemoradiotherapy; Group 5, complete excision and chemoradiotherapy. Survival was calculated from the time of diagnosis, and comparisons of survival were done by log-rank analysis. The mean survival was 4.3 months (range, 1.0-21 months). The mean survival based on treatment modalities were as follows: Group 1 (n = 10), 2.1 months, Group 2 (n = 8) ; 3.6 months; Group 3 (n = 7), 3.0 months; Group 4 (n = 14), 3.5 months, Group 5 (n = 8), 9.4 months. There was no significant difference in survival time between the various types of treatment modalities. Even though a small improvement in survival was observed with complete excision and aggressive multimodality therapy, nearly all ATCs remain unresponsive to ongoing treatment modalities and as such, present a therapeutic dilemma. A more effective treatment regimen should be sought in order to improve survival.
Treatment Outcome
;
Thyroid Neoplasms/mortality/surgery/*therapy
;
Survival Analysis
;
Radiotherapy, Adjuvant
;
Neoplasm Metastasis
;
Middle Aged
;
Male
;
Humans
;
Female
;
Combined Modality Therapy
;
Chemotherapy, Adjuvant
;
Carcinoma/mortality/surgery/*therapy
;
Aged, 80 and over
;
Aged
;
Adult
5.Warty Dyskeratoma with a Cutaneous Horn: Report of a case.
Ah Won LEE ; Hyun Joo CHOI ; Youn Soo LEE ; Seok Jin KANG ; Byung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1998;32(8):616-618
The clinical and pathological features of warty dyskeratoma are presented. Warty dyskeratoma is a rarely encountered, solitary, benign cutaneous tumor occurring most often on the head and neck and to our knowledge, no cases associated with cutaneous horn have been published in western literature. We experienced a case of warty dyskeratoma with a cutaneous horn occurring in a 70-year-old male, who had a 1.3 cm-sized and slowly growing nodule on his neck. A brief review of the literature, was made especially in relation to the pathological findings and histogenesis of warty dyskeratoma.
Aged
;
Animals
;
Head
;
Horns*
;
Humans
;
Male
;
Neck
6.Diver Death due to Underwater Explosion.
Joo Young NA ; Jeong Woo PARK ; Seok Hyun YOON ; Jong Shin PARK ; Byung Ha CHOI ; Youn Shin KIM
Korean Journal of Legal Medicine 2014;38(4):171-174
A 44-year-old man was cutting an outer plate of a ship, at a depth of 25 m below sea level. Following a sudden explosion, he was discovered unconscious and was carried to the surface by other divers. There was no evidence of vital signs upon arrival at the hospital. Postmortem computed tomography, which was performed prior to autopsy, revealed massive pneumocephalus in the brain, pneumohemothorax, diffuse lung contusions with multiple traumatic lung cysts, air-fluid level in the cardiac chamber of the chest, and pneumoperitoneum in the abdomen. Postmortem external examination showed a circular abrasion on the jaw, diffuse subcutaneous emphysema, and contusion in the right upper arm. An internal examination revealed intravascular air bubbles in all four chambers of the heart, and diffuse pulmonary trauma including contusion, laceration, and multiple traumatic cysts. Blast injury to the chest, and air embolism due to the underwater explosion were established as the underlying cause of death.
Abdomen
;
Adult
;
Arm
;
Autopsy
;
Blast Injuries
;
Brain
;
Cause of Death
;
Contusions
;
Diving
;
Embolism, Air
;
Explosions*
;
Heart
;
Humans
;
Jaw
;
Lacerations
;
Lung
;
Pneumocephalus
;
Pneumoperitoneum
;
Ships
;
Subcutaneous Emphysema
;
Thorax
;
Vital Signs
7.Thoracoscopic Sympathectomy for Hyperhidrosis Lowers Arterial Pressure Measured in Ipsilateral Arm.
Yong Seok OH ; Won Shik AHN ; Youn Suk LEE ; Seoung Hyun LEE
Korean Journal of Anesthesiology 1998;34(6):1216-1220
BACKGROUND: Thoracoscopic sympathectomy seems to be a safe therapeutic procedure without a severe complication. Hypotension has been often reported as one of postoperative complications, but intraoperative changes in blood pressure (BP) were not studied. However, authors' past experience of thoracic sympathectomy told that intraoperative BP reduction could be observed only when measured in ipsilateral arm. During general anesthesia, BP reduction might be a crucial, which could be associated with complication. Authors conducted this study to establish whether BP reduction is confined to ipsilateral arm, or is systemic phenomenon in thoracoscopic sympathectomy. METHODS: Twenty healthy, male and female patients scheduled for one stage thoracoscopic thoracic sympathectomy were prepared for this study. Without premedication, invasive BP monitoring was taken place in bilateral radial arteries. General anesthesia was induced with low dose of fentanyl, propofol and vecuronium. Endotracheal intubation was done with double lumen tube and anesthesia was maintained with variable concentrations of isoflurane in 100% oxygen. Sympathetomies were done for T2~3 during one lung ventilation. BP and palmar temperature were recorded at arrival, after one lung ventilation, after sympathectomy, 5 min, 10 min, after two lung ventilation. BPs and temperatures were analyzed by time and groups. RESULTS: Concurrent with initiation of sympathectomy, BP was reduced only in ipsilateral radial artery. Mean BP decrement was almost 11% (right side: 80 +/- 11 mmHg -> 71 +/- 15 mmHg; left side: 80 +/- 14 mmHg -> 71 +/- 9 mmHg; both of p<0.05). It was accompanied with ipsilateral palmar temperature elevation (right side: 1.28 degrees C; left side: 1.19 degrees C; both of p<0.05). CONCLUSION: Conclusively, BP reduction in thoracic sympathectomy is a change confined to ipsilateral arm, which seems because of peripheral vasodilation.
Anesthesia
;
Anesthesia, General
;
Arm*
;
Arterial Pressure*
;
Blood Pressure
;
Female
;
Fentanyl
;
Humans
;
Hyperhidrosis*
;
Hypotension
;
Intubation, Intratracheal
;
Isoflurane
;
Lung
;
Male
;
One-Lung Ventilation
;
Oxygen
;
Postoperative Complications
;
Premedication
;
Propofol
;
Radial Artery
;
Sympathectomy*
;
Vasodilation
;
Vecuronium Bromide
;
Ventilation
8.An Agiographic Study on Developemental and Spatial Relationship of Patent Ductus Arteriosus (PDA) and Aortic Arch in Right Ventricular Outflow Tract (RVOT) Obstruction.
DO Hyun KIM ; Youn Mo AHN ; Ha Balk LEE ; Kyoo Hwan RHEE ; Hahng LEE ; Seok Chol JEON
Journal of the Korean Pediatric Society 1988;31(9):1139-1145
No abstract available.
Aorta, Thoracic*
;
Ductus Arteriosus, Patent*
9.Cutaneous Plasmacytosis with Multiple Nodular Eruptions and Polyclonal Hypergammaglobulinemia.
Seung Yong JUNG ; Woo Seok KOH ; Sang Eun MOON ; Kwang Hyun CHO ; Jai Il YOUN ; Yoo Shin LEE
Annals of Dermatology 1994;6(2):183-187
We report two patients with multiple peculiar skin eruptions and polyclonal hypergammaglobulinemia. Both patients visited our hospital for the evaluation of asymptomatic multiple nodular eruptions on almost their entire body except for the lower extremities. Histologic examinations disclosed prominent infiltration of plasma cells and lymphoid follicular hyperplasia in the dermis but these plasma cells showed neither a mitotic figure nor atypicalities. Laboratory examinations showed polyclonal hypergammaglobulinemias and increased erythrocyte sedimentation rates. In spite of various investigations, the cause of the hypergammaglobulinemia remained obscure.
Blood Sedimentation
;
Dermis
;
Humans
;
Hypergammaglobulinemia*
;
Hyperplasia
;
Lower Extremity
;
Plasma Cells
;
Skin
10.Papillary Adenocarcinoma of Nonpigmented Ciliary Epithelium of the Eye.
Hyun Joo CHOI ; Yeong Jin CHOI ; Youn Soo LEE ; Eun Jung LEE ; Seok Jin KANG ; Byung Kee KIM ; Sang In SHIM
Korean Journal of Pathology 1998;32(12):1104-1107
Adenocarcinoma of the ciliary epithelium is a rare tumor, usually occuring in elderly patients who have a history of severe ocular trauma or chronic inflammation. We report an adenocarcinoma of the nonpigmented ciliary epithelium found within the phthisical globe of a 36-year-old female whose eye had been loss of vision since infancy. The mass, measured 4.0 x 4.0 cm, was relatively limited by sclera but had invasion to posterior portion. Histologically, the tumor was a compact mass which consisted of tubular and papillary structures with foci of the pleomorphic area. Strands of cells and individual cells were invested with thick basement membrane that have positivity for periodic acid-Schiff stain. Immunohistochemical staining showed strong reactivity for cytokeratin and epithelial membrane antigen, and focal for neuron-specific enolase and S-100 protein.
Adenocarcinoma
;
Adenocarcinoma, Papillary*
;
Adult
;
Aged
;
Basement Membrane
;
Epithelium*
;
Female
;
Humans
;
Inflammation
;
Keratins
;
Mucin-1
;
Phosphopyruvate Hydratase
;
S100 Proteins
;
Sclera