A clinical survey on the condyloma acuminatum in the army was carried out during the period of 16 months from July, 1976 to Dec., 1977 by means of ready-made chart and questionare. This study concems a series of 100 maIe patients treated in the ROK Army Hospital. The result can be summarized as follows: 1. 91% of the patients were between the age of 21 and 25, the commonest age being 24(31%) years. The average age was 23.6 years. 86%. of the patients experienced their first sexual contact between the age of 18 and 22, the commonest age being 20 (22%) and 2l(22%) years. The average age was 20years. 2. Predilection sites of the condyloma acuminatum were coronal sulcus (32%), perianal region(22%), glans penis(7%), urethral meatus(7%) and prepuce(4%) 3. Barmaid (58%) was the most frequently suspected sources of prsent infectian and other suspected sources were the prostitute (15%) and the lover (7%). 4. Among the 100 cases of condyloma acuminatum, 78 cases (78%) faund. their skin lesion 1 to 6 months after sexual contact and 49 cases (49%) found it within 8 months. Average incubation period was 3. 7 months. 5. Thirty two cases (32%) of condyloma acuminatum had a past history of other STD and 18 casea (18%) had other coincidently combined STD which were composed of syphilis (15%), urethritis (2%) and chancroid (1% ).
Chancroid ; Hospitals, Military ; Humans ; Sex Workers ; Skin ; Syphilis ; Urethritis

A case of lymphangioma circumscriptum which was hard to diagnose because of complicated clinical pictures, was described and the pathogenesis of the disease was reviewed, The 23 year-old male patient had palm sized, verrueous, oozing and crusted patch with some grouped vesicles on the right upper thigh since childhood. Histopathologically the verrucous lesion showed marked hyperkeratosis, acanthosis in the epidermis and proliferation and cystic dilatation of lymph vessels lined by a single layer of endothelium in the dermis, subcutis and muscular tissues. He was treated with surgical excision and skin graft and showed no recurrence over 3 months.
Dermis ; Dilatation ; Endothelium ; Epidermis ; Humans ; Lymphangioma* ; Male ; Recurrence ; Skin ; Thigh ; Transplants ; Young Adult

No abstract available.
Leg* ; Myocutaneous Flap*

Goltz syndrome is known as a rare mesoectodermal hereditary disease, characterized by focal dermal atrophies with hernias of adipose tissue and also associated with a multitude of possible skeletal, dental, ophthalmological and other abnormalities. We experienced a case of Goltz syndrome. An one day old female newborn had focal atrophic and telangiectatic skin lesions, microphthalmia, syndactyly and urinary tract abnormality. The finding of skin biopsy was consistent with focal dermal hypoplasia. We report the case with a brief review and related literatures.
Adipose Tissue ; Atrophy ; Biopsy ; Female ; Focal Dermal Hypoplasia* ; Genetic Diseases, Inborn ; Hernia ; Humans ; Infant, Newborn ; Microphthalmos ; Skin ; Syndactyly ; Urinary Tract

One hundred and seven patients with alopecia areata were studied in regard to the character of personality, emotional stress during their military life, socioeconomic status and their possible role in the pathogenesis of alopecia areata by ready-made chart and Minnesota Multiphasic Personality Inventory (M.M.P.I,) While only 55. 4% of out patients were enlisted men, 73. 0% of alopecia areata patients were soldiers suggesting that soldiers are more prone to develop alopecia areata. This trend was more apparent among soldiers who were less than 6 months in the service. In clinical scale, abnormal MMPI profiles were noted in 65 patients (60. 7%). Among abnormal MMPI profiles, hysteria scale is most common (23. 1%) and followed by hypochondriasis scale 18. 5%, psychiasthenia scale 16. 9%, and paranoia scale 12. 3%. The alopecia areata group showed significant difference in psychopathic deviate, schizophrenia, and paranoia which is high in person having psychotic symptoms and psychopathic personality. The neurotic triad or anxiety index is not significantly elevated.
Alopecia Areata ; Alopecia* ; Antisocial Personality Disorder ; Anxiety ; Humans ; Hypochondriasis ; Hysteria ; Male ; Military Personnel ; MMPI ; Outpatients ; Paranoid Disorders ; Schizophrenia ; Social Class ; Stress, Psychological

PURPOSE: It is well known that cyclooxygenase-2 (COX-2) is associated with carcinogenesis in many human cancers. In thyroid cancers, COX-2 expression in aging patients is known as a powerful prognostic factor of differentiated thyroid cancer. Therefore, in this study, we investigated the expression of COX-2 in cases of papillary thyroid cancer (PTC), as well as its association with other prognostic factors of thyroid cancer. METHODS: A total of 213 cases of papillary thyroid cancer were enrolled in this study and their clinicopathological characteristics were investigated retrospectively by a review of medicalrecords. Immunohistochemical staining for COX-2 was performed in the malignant tissue of the cases and the resultsof were then evaluated to determine if they were associated with other prognostic factors. RESULTS: The mean age of patients was 46 years (Range: 17~77 years old) and the tumor sizesranged from 0.1 to 5 cm (mean 1.2±0.9 cm). The pathological findings were as follows; thyroid capsule invasion in 101 patients (47%), lymph node metastasis in 76 patients (36%), multiplicity in 47 patients (22%), and bilaterality in 36 patients (17%). Positive results of immunohistochemical staining for COX-2 were noted in 131 patients (62%), however, the statistical analyses showed no significant association between COX-2 expression and other prognostic factors of papillary thyroid cancer. CONCLUSION: No association of COX-2 expression and prognostic factors of papillary thyroid cancer were found in this study. However, a larger prospectivestudy with survival analyses would provide a better understanding of thesignificance of COX-2 expression in cases of papillary thyroid cancer.
Aging ; Carcinogenesis ; Cyclooxygenase 2* ; Humans ; Lymph Nodes ; Neoplasm Metastasis ; Prognosis* ; Retrospective Studies ; Thyroid Gland* ; Thyroid Neoplasms*

OBJECTIVE: To evaluate the colonic motility and nutrients intake in children with spastic cerebral palsy (CP) and to compare the results with those of normal children. METHOD: Thirty-eight children with spastic CP were participated in this study. They took the radioopaque markers for 3 successive days. Then, abdominal X-ray was taken on the fourth day. Total and segmental colon transits were estimated by the simplified assessment of a single-film technique by Metcalf et al. The amounts of nutrients intake for 3 days were recorded and nutritional factors were analyzed by ESHA Food Processor. Then, daily intakes of the nutrients were compared with Recommended Dietary Allowance of the Korean Nutrition Society. RESULTS: Total and segmental colon transit time were more than 2 times delayed in children with spastic CP as compared with those of normal controls. Total colon transit time was significantly prolonged in quadriplegic and non-ambulatory children (p<0.05). On the evaluation of daily nutrients intake, most of nutritional factors were inadequate in children with spastic CP. CONCLUSION: The children with spastic CP had the problems in colonic motility and nutritional intake. Also, delayed colon transit time was significantly related with poor mobility. Therefore, early intervention for these problems will be required in spastic CP, especially quadriplegic and non-ambulatory children.
Cerebral Palsy* ; Child* ; Colon* ; Early Intervention (Education) ; Humans ; Muscle Spasticity* ; Recommended Dietary Allowances

PURPOSE: To demonstrate activation signals within the cerebellar cortex and to determine the side of thecerebellar cortex eliciting activation signals in response to complex motor tasks, as seen on EPI fMRI MATERIALS AND METHODS: Seven right-handed subjects (M:F=3:4;mean age, 30.3 years) underwent repetitive finger appositionwith the dominant right hand. Using a 1.5T MRI scanner, EPI fMR images were obtained. MR parameters used for EPIfMRI were TR/TE/Flip angle : 0.96 msec/64 msec/90 degree, FOV 22cm, 128 X 128 matrix, 10 slices, 10mm thickness whilethose for SE T1 weighted localized images were TR/TE : 450/16, FOV 23cm, 256 X 256 matrix. The paradigm was threesets of alternate resting and moving fingers for six cycles, resulting in times of 360 seconds (10 slices X 15 EPIX 6 cycles = 900 images). Image processing involoved the use of a 200mHz Dual Pentium PC with homemade software.T-testing (p<0.005) and time series analysis were performed, and to verify the locations of activated regions,resulting images were analyzed in a color-coded overlay to reference T1-weighted spin echo coronal images.percentage change in signal intensity (PCSI) was calculated from the processed data. RESULTS: All normal subjectsshowed significant activation signals in both the contralateral (left) primary motor cortex (PCSI=3.12%+/-0.96) andipsilateral (right) cerebellar cortex (PCSI=3.09%+/-1.14). Signal activation was detected in the contralateralsupplemental motor area (2.91%+/-0.82), and motor activation in the anterior upper half of the contralateralcerebellum (PCSI=2.91%+/-0.69). The difference in activation signals between both sides of the cerebellar cortexwas not statistically significant. All data were matched with time-series analysis. CONCLUSION: Bilateralcerebellar activation is associated with unilateral complex finger movements, as seen on fMRI. This result maysupport the recent neurological observation that the cerebellum may exert bilateral effects on motor performance.
Cerebellar Cortex ; Cerebellum* ; Fingers ; Hand ; Magnetic Resonance Imaging* ; Motor Cortex

Granular cell tumors (GCTs) have been reported in various tissues, especially the skin and subcutaneous soft tissue of the head and neck. We report a 60-year-old man who presented with intermittent headache and dizziness for 3 months, but no other neurological symptoms. Magnetic resonance imaging (MRI) showed the presence of a mass in the pituitary stalk, and contrast-enhanced MRI showed nodular enhancement in this region. The lesion was completely excised microscopically via a frontotemporal (pterional) approach. On pathological examination, a final diagnosis of a typical GCT was made.
Diagnosis ; Dizziness ; Granular Cell Tumor* ; Head ; Headache ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neck ; Pituitary Gland* ; Pituitary Neoplasms ; Skin

The effects of fentanyl, used as preloading drug to thiopental for induction of anesthesia, on the hemodynamic responses to endotracheal intubation were investigated in 60 surgical patients. Normotensive patients were randomly assigned to receive thiopental 5 mg/kg alone(N = 20, group A) or fentanyl 3 mcg/kg preloading 4 minutes before thiopental 3 mg/kg(N=20, group B) for induction of anesthesia. Hypertensive patients(N=20, group C) reeeived the same as group B. Electrocardiogram(EKG), mean arterial pressure(MAP), heart rate(HR), and rate-pressure product(RPP) were measured automatically before and during induction of anesthesia and after endotracheal intubation. The incidence of tachycardia were 20% in normotensive group and 25% in group C. Premature ventricular contracture or ST segment depression were appeared in 25% of patients in group C. Following intubation MAP, HR and RPP were all increased significantly but the change of them were more greater in group A than other groups. We concluded that blunting effects of the low dose fentanyl preloading used before thiopental induction to postintubation hypertension and tachycardia were statistically signifieant in normo-and hypertensive patients. But in clinical view, hypertensive patients should be managed more carefully. And further investigation seems warranted for the evaluation of preloading fentanyl dosage or combination of antihypertensive drugs and fentanyl.
Anesthesia ; Antihypertensive Agents ; Arterial Pressure ; Contracture ; Depression ; Fentanyl* ; Heart ; Heart Rate ; Hemodynamics* ; Humans ; Hypertension ; Incidence ; Intubation ; Intubation, Intratracheal* ; Tachycardia ; Thiopental