1.Red Blood Cell Transfusion in Autoimmune Hemolytic Anemia.
Youn Kyung KIL ; Young Jin CHOI ; Sung Ran CHO ; Hwi Jun KIM ; Hyun Ok KIM
Korean Journal of Clinical Pathology 1997;17(5):839-846
BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic*
;
Anemia, Hemolytic, Autoimmune
;
Autoantibodies
;
Blood Group Incompatibility
;
Blood Transfusion
;
Erythrocyte Transfusion*
;
Erythrocytes*
;
Hemolysis
;
Humans
;
Incidence
2.Red Blood Cell Transfusion in Autoimmune Hemolytic Anemia.
Youn Kyung KIL ; Young Jin CHOI ; Sung Ran CHO ; Hwi Jun KIM ; Hyun Ok KIM
Korean Journal of Clinical Pathology 1997;17(5):839-846
BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic*
;
Anemia, Hemolytic, Autoimmune
;
Autoantibodies
;
Blood Group Incompatibility
;
Blood Transfusion
;
Erythrocyte Transfusion*
;
Erythrocytes*
;
Hemolysis
;
Humans
;
Incidence
3.Two Cases of Quintuplets.
Hwa Il KWAG ; Kwang Ok LEE ; Wan LEE ; Young Youn CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1989;32(5):687-694
No abstract available.
Humans
;
Quintuplets*
4.Clinical Survey of Perinatal Mortality in Multiple Pregnancy.
Hoon KOOK ; Dong Hun CHO ; Hwa Il KWANG ; Kwang Ok LEE ; Young Youn CHOI
Journal of the Korean Pediatric Society 1989;32(3):321-330
No abstract available.
Female
;
Perinatal Mortality*
;
Pregnancy
;
Pregnancy, Multiple*
5.Early Diagnosis of Acute Appendicitis by Use of Ultrasonography in Emergency Department.
Byoung Youn OH ; Kyoung Soo LIM ; Young Ju LEE ; Won KIM ; Ok Kyoung CHOI
Journal of the Korean Society of Emergency Medicine 1998;9(4):586-594
BACKGROUND: In the most of emergency department, the diagnosis of appendicitis has been carried by clinical history, physical examination and plain X-ray. But the diagnostic accuracy by these methods was so low that unnecessary operation was common performed, and sometimes the operation was delayed till the physicians could confirm the acute appendicitis clinically. Although many kinds of diagnostic tools such as CT scan, laparoscope, and etc, we believe that ultrasonography(US) would be a quick and sensitive diagnostic method for the evaluation of acute appendicitis in the Emergency Department. METHODS: Forty-seven patients who were clinically suspected as acute appendicitis were evaluated with the grayscaled US by emergency physician. The probe of US was placed on maximal tender point of abdomen, and the appendix image was evaluated while probe was pressed deeply and gentry. When the blind loop was fecund at maximal tender point of abdomen, we evaluated the diameter of appendix, the presence of compressibility, peri-aspen-diceal fluid collection and other mass effect. As soon as the ultrasonographic evidences of the appendicitis were noticed, the operations were done and pathologic report were reviewed later. RESULTS: Among the forty-seven patients, forty patients were diagnosed as a appendicitis by US, and most common ultrasonic findings were as follows; 1) non-compressible blind loop larger than 5 mm in diameter, 2) wall thickening more than 3 mm, 3) peri-appendiceal fluid collection, 4) periappendiceal mass. Among remaining 7 patients in whom we could not get any positive findings of appendicitis, abdominal CT scan was carried in 2 cases who had direct and rebound tenderness on right lower abdomen, and CT scan showed the evidences of the appendicitis. The other 5 cases without rebound tenderness were observed far 2 hours, and abdominal pain was disappeared lately. Finally forty-two patients were operated and confirmed as acute appendicitis by pathologic reports; 24 were reported as suppurative appendicitis, and 12 cases of gangrenous appendicitis, 3 cases of perforated appendicitis, and 3 cases were peri-appendiceal abscess. The specificity of US in the diagnosis of acute appendicitis was 71.4%, and the sensitivity was 95.2%. CONCLUSIONS : In some patients suspected appendicitis, emergency physicians could diagnosis acute appendicitis accurately and rapidly by use of ultrasonography. Although the US was an actuate imaging modality to diagnosis acute appendicitis and evaluate its complications, we recommend a laparotomy or abdominal Cf scan in the patients with negative US findings in spite of presence of peritoneal irritation signs such as rebound tenderness and/or muscle guarding on right lower abdomen.
Abdomen
;
Abdominal Pain
;
Abscess
;
Appendicitis*
;
Appendix
;
Diagnosis
;
Early Diagnosis*
;
Emergencies*
;
Emergency Service, Hospital*
;
Humans
;
Laparoscopes
;
Laparotomy
;
Physical Examination
;
Sensitivity and Specificity
;
Tomography, X-Ray Computed
;
Ultrasonics
;
Ultrasonography*
6.Occupational Contact Urticaria Syndrome Induced by Cefotiam Dihydrochloride in a Nurse.
Hye Jeong CHOI ; Ji Youn SONG ; Young Min PARK ; Chung Won KIM ; Hyung Ok KIM
Annals of Dermatology 2003;15(3):113-115
We herein report a case of occupational contact urticaria syndrome induced by cefotiam di-hydrochloride in a nurse. She had generalized pruritic wheals accompanied by palpitations and tachypnea during the preparation of cefotiam solution. A scratch patch test with cefotiam di-hydrochloride, a major component of cefotiam ingredient showed multiple erythema and wheals within 5 minutes, accompanied by palpitations and tachypnea. No delayed type reaction was observed. Based on her clinical history and scratch test result, we diagnosed her condition as contact urticaria syndrome caused by cefotiam.
Cefotiam*
;
Erythema
;
Patch Tests
;
Tachypnea
;
Urticaria*
7.Two Cases of Goitrous Hypothyroidism in Siblings.
Kwang Ok LEE ; Hwa Il KWAG ; Hoon KOOK ; Young Youn CHOI ; Tai Joo HWANG
Journal of the Korean Pediatric Society 1990;33(1):129-134
No abstract available.
Humans
;
Hypothyroidism*
;
Siblings*
8.The effects of physical training on antioxidative status under exercise-induced oxidative stress.
Nutrition Research and Practice 2007;1(1):14-18
This study investigated the effect of physical training and oxidative stress on the antioxidative activity and on plasma lipid profile. Forty eight rats were given either a physical training or no training for 4 weeks and were then subdivided into 3 groups: before-exercise (BE); during-exercise (DE); after-exercise (AE). The antioxidative activity was evaluated with the activities of catalase in plasma and superoxide dismutase (SOD), the ratio of reduced glutathione/oxidized glutathione (GSH/GSSG) and the level of malondialdehyde (MDA) in liver. The plasma concentrations of triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C)) were also compared. Compared to those of non-training group, catalase activities of training group were lower before exercise but higher during and after exercise. SOD activities were higher regardless of exercise. GSH/GSSG ratio was higher before exercise but was not significantly different during exercise and even lower after exercise. There were no differences between non-training group and training group in MDA levels regardless of exercise. Compared to those of non-training group, atherosclerotic index of training group was lower after exercise and there were no significant differences before and during exercise. There were no differences between non-training group and training group in HDL-C regardless of exercise. These results suggest that moderate physical training can activate antioxidant defenses and decrease the atherosclerotic index and this beneficial effect is evident under exercise-induced oxidative stress.
Animals
;
Catalase
;
Cholesterol
;
Glutathione
;
Liver
;
Malondialdehyde
;
Oxidative Stress*
;
Plasma
;
Rats
;
Superoxide Dismutase
;
Triglycerides
9.Effect of Diabetes Education Program on Glucose Metabolism and Lipid Metabolism, Self-efficacy in NIDDM Patients.
Hyoung Sook PARK ; Yun Mi LEE ; Youn Ok CHOI ; Eun Suk BAE ; Jung Hyun NA ; Mi Sook KIM
Korean Journal of Rehabilitation Nursing 2001;4(2):165-178
The purpose of this study is to determine the effect of diabetes education program on Glucose Metabolism(blood sugar. HbAlc) and Lipid Metabolism(total cholesterol. triglyceride. low density lipoprotein. high density lipoprotein). Self-efficacy in non-insulin independent diabetes mellitus. The study design was a non equivalent control group pre-test post-test design. Data for the study were collected from March 12 to June 19, 2001. Sixty-two research subjects were assigned to experimental (36) and control (26) groups. The collected data was analyzed using the Chi-Square test. t-test by spsswin program The results are as follows: 1. Experimental group had higher level of glucose metabolism than control group(FBS: t=-3.317. p=.002. HbAlc: t=-4.956. p=.000). 2. Level of lipid metabolism were partly a significant different between experimental group and control group(Triglyceride: t=-2.108. p=.039). 3. Experimental group had higher efficacy score than control group(t=4.651. p=.000). In conclusion. the study supported the effects of diabetes education program to increase metabolism and self-efficacy. Further study with a longitudinal design is suggested to verify the effect of diabetes education program in NIDDM and standardized diabetes education program.
Cholesterol
;
Diabetes Mellitus
;
Diabetes Mellitus, Type 2*
;
Education*
;
Glucose*
;
Humans
;
Lipid Metabolism*
;
Lipoproteins
;
Metabolism*
;
Research Subjects
;
Triglycerides
10.The Effects of Dumbbell, Walking, and Yoga Exercise Interventions for the Community-Dwelling Women.
Kyung Rim SHIN ; Youn Hee KANG ; Kyung Ae CHOI ; Hyo Jin BAEK ; Mi Jin CHOI ; Ok Jong YUN
Journal of Korean Academy of Adult Nursing 2006;18(5):771-780
PURPOSE: The purpose of this study was to examine the effects of exercise intervention, including dumbbell(weight lifting), walking, and yoga, on the body composition, physiologic factors, body image, and perceived health in the community-dwelling women. METHOD: This study utilized pretest-posttest design with three types of exercise interventions. The types of exercise intervention included dumbbell, walking, and yoga. RESULTS: A total of 136 subjects were included: 49 for dumbbell, 67 for walking, and 20 for yoga. As measures of body composition, BMI, body weight, and body fat rate were significantly improved only after dumbbell intervention(p<.01). Systolic blood pressures were significantly decreased in the groups of dumbbell and walking. Diastolic blood pressure was significantly declined only in the walking group. Vital capacities and body image were improved in all groups(p<.01). However, total cholesterol levels were not improved in all groups(p>.05) and none of the measures for perceived health state were not significantly changed in all groups(p>.05). CONCLUSION: From the findings of this study, it was demonstrated that the effects of exercise interventions were differentiated by their types and variables to be affected. Therefore, future studies that apply the tailored exercise intervention to each age-categorical group are needed.
Adipose Tissue
;
Blood Pressure
;
Body Composition
;
Body Image
;
Body Weight
;
Cholesterol
;
Female
;
Humans
;
Vital Capacity
;
Walking*
;
Yoga*
;
Surveys and Questionnaires