No abstract available.
Pancreatic Polypeptide*

No abstract available.
Coronary Artery Disease* ; Coronary Vessels* ; Education* ; Health Behavior*

No abstract available.
Nitric Oxide*

Lidex(Fluacinonide) 0.05% in FAPG base is a new fluorinated topical corticosteroid. 30 patients with different steroid responsive dermatoaes were treated with 0. 05% Lidex. The diagnosis included atopic dermatitis, contact dermatitis, neurodermatitis, seborheic dermatitis, nummular eczema, psoriasis vulgaris, chronic eczema and pustulosis pahmaris et plantaris. In the majority of cases Lidex cream produced excellent to good result(70%) after unoccluded application 3 times daily for 10 days. Two patients complained burning or itching sensation after the initial application of Lidex. 0.05% Lidex was compared with 0. 25% Desoxymethasone cream and 0. 25% Fluocortolone cream and was found slightly more effective in Lidex.
Burns ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Desoximetasone ; Diagnosis ; Eczema ; Fluocinonide* ; Fluocortolone ; Humans ; Neurodermatitis ; Pruritus ; Psoriasis ; Sensation

Multiple basal cell epithelioma on the face is a rare disease and the lesions are hard to indistinguish from multiple trichoepithelioma. The 15-year-old school girl has been suffered from multiple small pea-sized, slightly waxy appearing skin lesions on the face for 4 years. She has no history of arsenic ingestion; irradia tion and previous dermatoses. Physical examination and X-ray films (chest, mandibule and skull) showed no pathological findings. Biopsy findings revealed basal cell epithelioma cells.
Adolescent ; Arsenic ; Biopsy ; Carcinoma, Basal Cell* ; Eating ; Female ; Humans ; Physical Examination ; Rare Diseases ; Skin ; Skin Diseases ; X-Ray Film

We report a case of atrophie blanche which was accompanied by cryoglobulinemia. The patient, 17-year-old female, have had recurrent painful ulcerations and ivory-white atrophic scars with telangiectases surrounded by hyperpigmentation. On histological examination, vessel wall thickening and hyalinization of the intima, partial vascular occlusion, vascular proliferation and mild perivascular chronic inflammatory cells infiltration and hemorrhage in the upper dermis were noted. The patient had been treated with dipyridarnol(Persantin) and acetylsalicylic acid hut the lesions had been waxed and waned.
Adolescent ; Aspirin ; Cicatrix ; Cryoglobulinemia* ; Dermis ; Female ; Hemorrhage ; Humans ; Hyalin ; Hyperpigmentation ; Telangiectasis ; Ulcer

This study was designed to investigate the effect of substitution of strontium for calcium on mechanical activity in isolated perfused spontaneously beating rat hearts. The mechanical activity of the hearts of Langendorff's preparation in conditions of low calcium and strontium-substitution for calcium was compared. The effect of norepinephrine and verapamil were also observed in those conditions. The results were as follows: 1. In low calcium, the mechanical activity of the heart preparation was significantly reduced, but when the equimolar strontium was substituted for the reduced calcium, the activity was kept at similar level to the normal condition. 2. When equimolar strontium was substituted for the total calcium in perfusate, the heart preparation stopped its beating, and it was not restored in spite of reperfusion with normal calcium perfusate. 3. Norepinephrine-induced positive inotropic effect was inhibited in low-calcium condition especially with low concentration of norepinephrine, but not in strontium-substitution for calcium. 4. Verapamil reduced the activity of the heart both in low-calcium and strontium-substitution as well as in normal calcium conditions. From above results, it was concluded that strontium served as a substitute of calcium in maintaining mechanical activity and in responsiveness to norepinephrine, and the influx of strontium through cell membrane is inhibited by verapamil as the influx of calcium.
Animals ; Calcium ; Cell Membrane ; Heart* ; Norepinephrine* ; Rats* ; Reperfusion ; Strontium* ; Verapamil

The present study was undertaken to inveatigate whether contaet sensitivity was decreased or not in patients with atopic dermatitis, and to investigate phagocytic function of neutrophils in patients with atopic dermatitis. 1. Dinitrochlorobenzene (DNCB), a compound which uniformly induce hypersensitivity in normal individuals, had been used in the preaent study to investigate cutaneous anergy in 16 patients with atopic dermatitis. Sensitizing does of DNCB (2,000 microgram) was applied and examined at 7th and 14th day for a spontaneous flare. In the absence of spontaneous flare, challenge dose (50microgram) was reapplied and examined. Seven of the 16 cases (43.8%.) had positive reaction to DNCB. These result showed decreased contact sensitivity in patients with atopic dermatitis, which suggested some defect in the cell-mediated immunity in patients with atopic dermatitis. 2. There were some evidence that susceptibility to certain infection was increased in patients with atopic dermatitis. For investigating killing function in phagoeytosis of neutrophils in patients with atopic dermatitis, nitroblue tetrazolium dye reduction (NBT) and stimalated NBT test had performed in 35 cases of atopic dermatitis and 20 cases of healthy control. 1) There was no significant difference in the mean percentage and absolute number of NBT positive neutrophils between whole group of atopic dermatitis (8. 4+4. 9%, 301.2+225.6) and control group (6. 9+2. 9%, 246.2+143. 8). 2) The mean percentage and absolute number of stmulated NBT poeitive neutrophils in whole group of atopic dermatitis (19.6+7.3%, 702. 1+377. 2) did not differ significantly from control group (22.7+5.3%, 812.2+382.2). 3) There was no significant difference in the mean value of NBT aad stimulated NBT test in comparing the mild groud, moderate group and severe group with control group. These resuIts suggested that killing function in phagocytosis of neutrophils in patients with atopic dermatitis was not impaired.
Dermatitis, Atopic* ; Dermatitis, Contact ; Dinitrochlorobenzene* ; Homicide ; Humans ; Hypersensitivity ; Immunity, Cellular ; Neutrophils ; Nitroblue Tetrazolium ; Phagocytosis

The effects of Cryosurgery of the ciliary body on the aqueous humor dynamics of ten albino rabbits were studied by perfusion experiments. The cryo-probe (tip diameter, 3 mm) was frozen by dry ice and alcohol mixture and applied over the full circumference of the eye 2 mm from the limbus for 30 seconds. Eight applications were made in each eye. Intraocular pressure fell during the first 10 days after surgery, the amount of fall averaged 2.5 mmHg (12.6% of the pre-treatment level). Thereafter the intraocular pressure rose gradually in all eyes and reached almost to the original level 3 weeks after surgery. Facility of outflow changed inconsistently, showing no definite pattern. Aqueous flow showed significant reductions during the 2 to 3 weeks after treatment, then gradually recovered. There was no significant reduction in flow after the end of 3 weeks. No complications were encountered except mild iridocyclitis during the first week. The unsatisfactory outcome of this cryotherapy is considered to be due to the insufficient freezing of the ciliary body, and more applications is recommended in order to produce more sustained reduction of intraocular pressure.
Aqueous Humor ; Ciliary Body ; Cryosurgery ; Cryotherapy ; Dry Ice ; Freezing ; Intraocular Pressure ; Iridocyclitis ; Perfusion ; Rabbits*

Three cases of pseudoxanthoma elasticum are presented and the literatures are reviewed. Two cases were presented with the marked cutaneous manifestation of this condition and angioid streak. One case was presented with only the marked skin lesion of this condition on both axilla and neck. Typically involved skin was shown to be speckled with pea-sized yellowish numorous papules. Typical elastic tissue degeneration was found in the involved skin. No genetic background was discovered in the patients.
Angioid Streaks ; Axilla ; Elastic Tissue ; Humans ; Neck ; Pseudoxanthoma Elasticum* ; Skin