No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*

No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*

No abstract available.
Blood Donors* ; Humans ; Phenotype*

Prolonged ischemic-reperfusion induces cellular damages and apoptosis in rat skeletal muscle. Reactive oxygen species generated during reperfusion time induce expression of various genes and apoptosis. Among apoptosis-related gene products, Bcl-2 and Bax regulate the apoptotic response by inhibiting and promoting cell death, respectively. The purpose of this study was to observe the age-related alertation of expression profile of Bcl-2 and Bax in rat tibialis anterior muscle and soleus muscle following ischemia-reperfusion. 9 weeks, 30 weeks, and 65 weeks old male Sprague-Dawley rats were divided into control and ischemia groups. Ischemia group was divided into 3 subgroups based on reperfusion time. For ischemia, left commom iliac artery was occulded for 4 hours using rodent vascular clamps. The animals were sacrificed at hours 0, 3 and 24 after onset of reperfusion and tibialis anterior and soleus muscles were removed. Muscle tissues were embedded in paraffin and 6 micrometer sections were made. The expression level of Bcl-2 and Bax were examined using immunohistochemical methods. The results obtained were as follows; 1. In control group, immunoreactivities (IMRs) of Bcl-2 and Bax were weak or moderate in 30 weeks old rats and were trace in 9 and 65 weeks old rat. 2. In control group, IMRs of Bcl-2 and Bax in tibialis anterior muscle were more higher than those in soleus muscle, but not significantly. 3. In ischemia group, IMRs of Bax were increased with aging. 4. In ischemia group, IMR of Bax in tibialis anterior muscle was higher than that in soleus muscle. These results suggested that the increased IMR of Bax may be related to increasing of ischemic injury, and both old skeletal muscle and tibialis anterior muscle are susceptabile to ischemic injury of rat skeletal muscle.
Male ; Humans ; Rats ; Animals

Prolonged ischemic-reperfusion induces cellular damages and apoptosis in rat skeletal muscle. Such injury takes place in the phase of reperfusion following ischemia induction in part via regulating of apoptosis-related gene inductions. The present study was performed to examine the age-related alertation of expression of apoptosis in rat tibialis anterior and soleus muscles following ischemia-reperfusion. 9 weeks, 30 weeks, and 65 weeks old male Sprague-Dawley rats were divided into 2 groups such as controls and ischemia. For ischemia, left commom iliac artery was occulded for 4 hours using rodent vascular clamps. The tibialis anterior and soleus muscles were removed 0, 3, and 24 hours after onset of reperfusion. Muscle samples were embedded in paraffin and 6 micrometer sections were made. The apoptotic reactions was detected using TUNEL methods. The results obtained were as follows; 1. In control groups, the number of apoptosis was increased with aging, but not significantly. 2. In ischemia groups, the number of apoptosis was increased at 3 hours after ischemia, and decreased at 24 hours after ischemia. 3. In ischemia groups, the number of apoptosis was increased with aging. 4. In ischemia groups, the number of apoptosis in the tibialis anterior muscle was higher than that in soleus muscle. These results suggested that the ischemic injury of the rat skeletal muscle is increased with aging and that tibialis anterior muscle is more susceptabile to ischemic injury than soleus muscle.
Male ; Humans ; Rats ; Animals

Fibroma of tendon sheath is a benign, soft tissue tumor that presents as a painless mass in the distal portion of an extremity. It is a slow-growing, dense, fibrous nodule which firmly attaches to the tendon sheath, and usually occurs in adults between the age of 20 and 50 years old. Histopathologically, it shows a well-demarcated nodule consisting of haphazardly-arranged, fibroblast-like spindle cells, which are embedded in a dense collagenous matrix. It is thought to be either a reactive process or a neoplasm, and the recurrence rate after excision is reported to be 24%. Herein, we present a typical case of fibroma of tendon sheath in a 39-year-old female, who presented with a firm nodule on her left 2nd finger. This was confirmed by histopathologic findings. The information described above should carefully be taken into consideration during differential diagnosis of soft tissue tumors of the hand.
Adult ; Collagen ; Diagnosis, Differential ; Extremities ; Female ; Fibroma* ; Fingers ; Hand ; Humans ; Middle Aged ; Recurrence ; Tendons*

Chilblain lupus erythematosus is a special, relatively rare subtype of chronic cutaneous lupus erythematosus. Usually, discoid lesions precede or occur concurrently with perniotic lesions, and about 20% of the patients later develop systemic lupus erythematosus. Herein, we present a 26-year-old female patient who developed erythematous to purplish scaly and crusted papules on the palms, fingers and toes. She also had erythematous hyperkeratotic plaques on the ears and scalp with scarring alopecia that was consistent with discoid lupus erythematosus. Histopathologic finding revealed perivascular and periappendigeal lymphocytic infiltration and fibrin deposition in dermal blood vessels. Therefore, this represents a case of chilblain lupus erythematosus which is a rare subtype and shows typical clinical and histopathologic findings.
Adult ; Alopecia ; Blood Vessels ; Chilblains* ; Cicatrix ; Ear ; Female ; Fibrin ; Fingers ; Humans ; Lupus Erythematosus, Cutaneous ; Lupus Erythematosus, Discoid ; Lupus Erythematosus, Systemic ; Scalp ; Toes

BACKGROUND: The C-reactive protein(CRP) is one of the "acute phase" proteins and it is known to be the most sensitive indicator of the inflammatory and/or necrotic process. Traditional methods for measuring CRP are capillary precipitation assay and latex agglutination assay. However, these methods have low sensitivity and provide only qualitative results. Recently the development of specific and very sensitive assays for CRP using highly specific monoclonal antibodies for CRP have done, including radioimmunoassay, nephelometric assay(NA), and turbidimetric immunoassay(TIA). We evaluated the Hitachi 7600-110(R)(Hitachi Co., Japan) using TIA in the measurement of CRP and compared its results to those of the the LX-M(R)(Eiken Chemical Co., Japan) using NA in order to replace the Hitachi 7600-110(R) for quantitative analysis of CRP. METHODS: CRP were measured by the Hitachi 7600-110(R) using TIA and the LX-M(R) using NA in the sera from 106 patients. The relationship between results of Hitachi 7600-110(R) and LX-M(R). By performing 20 repetitive assays at three levels of CRP control serum and pooled sera, within-run, within-day, and between-day precision of the Hitachi 7600-110(R) were established. RESULTS: When the CRP value of 4.60 +/- 5.65 mg/dL by the Hitachi 7600-110(R) was compared with that of 3.71 +/- 4.32 mg/dL by the LX-M(R), coefficients of correlation of 0.994 was obtained. The regression equation was Y(Hitachi 7600-110(R)) = 1.298 X(LX-M(R)) - 0.211(r=0.994, n=106). CVs of CRP measured by Hitachi 7600-110(R) were 5.45% at 0.82 mg/dL, 1.32% at 2.39 mg/dL, and 2.37% at 4.62 mg/dL. The precision was excellent in each group. The linearity was acceptable, and sample to sample carry-over was 0.8%. CONCLUSIONS: The Hitachi 7600-110(R) using TIA, compared with the LX-M(R) using NA, showed good coefficient of correlation and excellent precision. Therefore the Hitachi 7600-110(R) can replace the LX-M for quantitative analysis of CRP.
Agglutination ; Antibodies, Monoclonal ; C-Reactive Protein* ; Capillaries ; Humans ; Latex ; Radioimmunoassay

Primary cutaneous diffuse large B-cell lymphoma is characterized by a diffuse infiltration of atypical large centroblasts and immunoblasts through the dermis without extracutaneous involvement. We report a case of primary cutaneous diffuse large B-cell lymphoma in a 71-year-old female, who presented with a solitary erythematous nodule on the inner thigh. Physical examination and staging work-up revealed no other extracutaneous or systemic involvement. After radiotherapy, the skin lesion had almost cleared, and no evidence of extracutaneous involvement was observed for 4 months.
Aged ; B-Lymphocytes* ; Dermis ; Female ; Humans ; Lymphoma, B-Cell* ; Physical Examination ; Radiotherapy ; Skin ; Thigh

Central nervous system (CNS) involvement may occur in chronic schistosomiasis. It can be produced by any Schistosome species but happens most frequently in chronic Schistosoma japonicum infection. CNS involvement by S. mansoni is relatively rare but it may occur by embolization of eggs or ectopic migration of adult worms. A case of cerebral schistosomiasis caused by S. mansoni in a 40-year-old man, who had worked in Yemen, is reported. Biopsies taken from the cerebellar vermis and the roof of the fourth ventricle, showed granulomatous inflammation due to eggs. S. mansoni was identified by stool examination and ELISA using serum and CSF. This is the first imported case of cerebral schistosomiasis in Korea.
Adult ; Brain Diseases/diagnosis/*pathology/surgery ; Case Report ; Human ; Male ; Schistosomiasis mansoni/diagnosis/*pathology/surgery