PURPOSE: Children in migrant villages in Kyrgyzstan have a high incidence of anemia and need effective health promotion programs. The purpose of this study was to evaluate a pilot study of a health promotion project for infants and toddlers based on community participation.METHODS: This was a retrospective study conducted to evaluate the effectiveness of the project. The project was carried out by nurses at a public health center, community health workers, and local residents in a migrant village. After the operational system of the project was established, health assessments, child-care education, provision of vouchers for iron supplements, and activities to improve residents' awareness were conducted during 6 months among 100 children, of whom 85 were finally analyzed.RESULTS: In international health projects, close cooperation of the project team with community residents and health workers is important. Access to the community-based program was feasible in the socially and economically poor migrant village, and improvements were shown in children's anemia and awareness of health care.CONCLUSION: By focusing on the effective aspects of this preliminary project, plans to utilize community health workers and promotion strategies can be added to the main project to improve health promotion among children in this area.
Anemia ; Child Health ; Child ; Community Health Centers ; Community Health Workers ; Community-Based Participatory Research ; Consumer Participation ; Delivery of Health Care ; Education ; Health Promotion ; Humans ; Incidence ; Infant ; Iron ; Kyrgyzstan ; Pilot Projects ; Program Evaluation ; Public Health ; Retrospective Studies ; Transients and Migrants

PURPOSE: To evaluate the diagnostic value of source images of 3D TOF MR angiography in patients with hemifacial spasm. MATERIALS AND METHODS: Thirteen patients with surgically-confirmed hemifacial spasm and 30 who were not suffering from this condition were included in this study. T1 and T2-weighted images and 3D TOF MR angiography were performed. In 43 randomly-selected individuals, we retrospectively determined whether source images obtained during 3D TOF MR angiography could be used to evaluate symptoms. The results were correlated with surgical findings. RESULTS: Sensitivity was 92% and specificity was 86%. In all 13 patients with hemifacial spasm, neurovascular compression was detected during their operation. Offending vessels were the anterior inferior cerebellar artery (AICA) in four cases, the posterior inferior cerebellar artery (PICA) in seven, both the vertebral artery and PICA in one, and the vertebral vein, also in one. There were ten false-positive cases in the asymptomatic control group, nine of which showed neurovascular contact in the root entry zone of the facial nerve; one case showed indentation of the pons. CONCLUSION: Source images obtained during 3D TOF MR angiography are useful in the preoperative evaluation of hemifacial spasm.
Angiography ; Arteries ; Facial Nerve ; Hemifacial Spasm* ; Humans ; Pica ; Pons ; Retrospective Studies ; Sensitivity and Specificity ; Veins ; Vertebral Artery

Background: The Korean Red Cross has conducted serologic tests for C, c, E, e antigens and found 18 D-- donors.In this study, we performed RHCE genotyping to identify the molecular characteristics of the serologic D-- blood type in Korean blood donors. Methods: We performed RHCE-specific PCR-based electrophoresis to check the amplification pattern of each exon.Sanger sequencing was conducted to find the variants in the nucleotide sequence. We determined the RHCE genotype based on the electrophoresis and Sanger sequencing results. Results: Total eight out of 18 D-- donors were participated in this research. In the PCR-based electrophoresis tests, RHCE exons 3, 4, and 6 were not amplified in samples #4, #6, and #8. Also, sample #2 showed an abnormal band pattern of RHCE exon 9. The Sanger sequencing results showed that the nucleotide sequences of the RHCE exons 5, 7, and 8 in samples #4, #6 and #8 corresponded to the nucleotide sequences of RHD exons 5, 7, and 8, respectively, suggesting the possibility of a RHCE-RHD(3-8)-RHCE hybrid allele. The nucleotide sequences of RHCE exons 7 and 8 in sample #2 were the same as the nucleotide sequences of RHD exons 7 and 8, respectively.In samples #1, #3, #5, and #7, no specific variants known to cause D-- phenotype were found. Conclusion RHCE genes partially replaced by the RHD genes were found in four out of eight participants and three of them were identified as ?RHCE*02N.07, which is known as the RHCE null allele. A further study with complete RHCE sequencing could be helpful for an understanding of the molecular mechanisms of samples in which no significant variants were identified.

BACKGROUND: Minerals are essential nutrients of human body and related with various diseases. Some minerals may be associated with endocrine function. Especially, chromium is known to enhance the action of insulin. The correlation of minerals with DM has not been studied in Korea yet. Therefore, to know whether there is any significant difference of minerals concentration and component between DM patient and non-DM patient, the quantity of each mineral in the hair of patients and controls was measured. If there is any significance, a guideline of nutritional therapy with minerals could be proposed and recommended. METHOD: An analysis of hair was performed on the type II diabetic patients and non-diabetic patients who visited Severance hospital outpatient clinic from April, 2001 to January, 2002. Hairs were obtained from each subject and were analyzed into the concentration of mineral using an atomic absorption spectrophotometer. The concentration of each element between the two groups was compared by t-test analysis. RESULTS: The concentration of copper, sodium, chromium, sulfur, and antimony was significantly different; the level of copper was significantly lower in the diabetic group (P=0.013). On the other hand, the levels of sodium, chromium, sulfur, and antimony were significantly higher in the diabetic group (P=0.013, 0.0001, 0.010, 0.0001). CONCLUSION: Previous studies have suggested that the concentration of chromium in diabetic patients' blood was lower than those in normal population. However, this study showed that the measured amount of chromium in hair was significantly higher in the diabetic group. This result warrants a study on the correlation between the concentration of chromium in blood and hair, and also, on the mutual relationship of other minerals (copper, sodium, sulfur, and antimony) which also showed significant difference in this study.
Absorption ; Antimony ; Chromium ; Copper ; Hair* ; Hand ; Human Body ; Humans ; Insulin ; Korea ; Minerals ; Outpatient Clinics, Hospital ; Sodium ; Sulfur

High-intensity focused ultrasound (HIFU) has been regarded as a non-surgical, minimally invasive therapeutic option for patients who prioritize uterus-conservation. Although many studies have shown that HIFU therapy is a safe and effective treatment of uterine fibroid, not all fibroids are suitable for HIFU due to risks of serious complications. We experienced three cases of complications after the HIFU ablation for huge uterine fibroids, including two cases of rapid myoma enlargement and one case of heavy vaginal bleeding.
Female ; Humans ; Leiomyoma ; Myoma ; Single Person* ; Ultrasonography* ; Uterine Hemorrhage

Interest in the correction of jaw deformities has increased due to the development of techniques and instruments of jaw operation. The accurate position of the mandibular foramen and lingula is important for the prevention of the complications and successful inferior alveolar nerve block. This study was conducted on 104 dried mandibles (65 males, 39 females) from Korean cadaver. The positions of the mandibular foramen and lingula were measured on the coronoid notch, occlusal plane, mandibular notch, gonion, koronoid and kondylion. The structures of the mandibular foramen and lingula were determined and the thickness of ramus and the angle of mandible were measured. Independent t-tests and paired t-tests were performed to determine the statistically significant difference. The results as follows; The line between coronoid notch and posterior border of ramus was located on the same level with the tip of lingula in 42.2% of the cases, and in between the mandibular foramen and the tip of lingula in 33.8% of the cases. The occlusal plane was located on the level between the mandibular foramen and the tip of lingula in 47.7% of cases, and on the same level with the tip of lingula in 35.6% of the cases. The line between lower end of the mandibular notch to inferior border of the mandible, in parallel to the posterior border of the mandibles, met the tip of lingula in 55.8% of the cases. The mandibular foramen was located posteriorly to the midpoint on the anteroposterior (AP) width of the ramus. It was located at 57.3% of AP width from the coronoid notch and 56.5% from the occlusal plane. The mandibular foramen and the tip of lingula were located superiorly to the midpoint on the vertical height of the ramus, on the 48.5% and 35.7% of vertical distance from the coronoid notch, respectively. The mandibular foramen was located at 40% of the length on the line from the gonion to the koronion. The results of this study will provide important morphometric information to prevent the complications in mandibular surgery and also provide the basis for the development of the new techniques.
Cadaver ; Congenital Abnormalities ; Dental Occlusion ; Humans ; Jaw ; Male ; Mandible ; Mandibular Nerve

Although laryngomalacia is the most common cause of congenital stridor in infancy, it is a benign, self-limited disease which usually resolves by the age of 18 months with no long- term sequelae. Nevertheless, infants who suffered from recurrent stridor and respiratory distress should be evaluated for other causes of stridor such as cardiopulmonary anomalies. We report 3 cases of infants who had recurrent stridor and respiratory distress from their early infancy. Case 1 had a double aortic arch and a tracheomalacia, case 2 had a hypoplasia of the right lung, and case 3 had a horseshoe lung as well as scimitar syndrome. Physicians should be alert for the possibility of the congenital cardiopulmonary abnormalities in infants with recurrent stridor and/or respiratory distress.
Aorta, Thoracic ; Dyspnea ; Humans ; Infant ; Laryngomalacia ; Lung ; Respiratory Sounds ; Scimitar Syndrome ; Tracheomalacia

Intestinal metaplasia of the stomach is a common metaplastic lesion associated with chronic gastritis and mucosal atrophy. However, squamous metaplasia is a comparatively rare condition. On endoscopy, squamous metaplasia is usually observed as a whitish mucosal lesion in the lesser curvature of the cardiac region of the stomach. When Lugol's iodine solution is applied, the lesion stains brown in the same way as normal esophageal mucosa. We report a case of 79-year-old man with a whitish flat lesion in the lesser curvature of the cardiac region on surveillance endoscopy after endoscopic treatment of gastric adenoma. The endoscopic biopsy showed stratified squamous epithelial mucosa.
Adenoma ; Atrophy ; Biopsy ; Coloring Agents ; Endoscopy ; Gastritis ; Iodides ; Iodine ; Metaplasia ; Mucous Membrane ; Stomach

A subepicardial aneurysm is a rare, life-threatening complication of acute myocardial infarction. Clinical and pathologic features include abrupt interruption of the myocardium, a narrow neck, and a propensity for progression to sudden transmural rupture. Echocardiography, magnetic resonance imaging, and computed tomography are diagnostic imaging tools used for identifying subepicardial aneurysms after acute myocardial infarction. Surgical repair is thought to be the best treatment modality for this type of aneurysm. Here, we report a case of a 72-year-old woman with subepicardial aneurysm of the left ventricle after acute myocardial infarction. She was treated using surgical repair without complications.
Aged ; Aneurysm ; Diagnostic Imaging ; Echocardiography ; Female ; Heart Aneurysm ; Heart Ventricles ; Humans ; Magnetic Resonance Imaging ; Myocardial Infarction ; Myocardium ; Neck ; Rupture

BACKGROUND: A piroxicam patch has been widely used to treat musculoskeletal pain. The aim of this study was to assess the pharmacokinetic (PK) characteristics and skin irritation of Murupe(R) patch (piroxicam 96 mg) compared with Trast(R) patch (piroxicam 96 mg) in healthy volunteers. METHODS: A randomized, open-label, 2-way crossover study was conducted in 12 healthy Korean male subjects. They were allocated to one of the two treatment sequences of RT and TR (R, reference drug, Trast(R) patch; T, test drug, Murupe(R) patch). Each patch was applied to the subject once during 48 hours. Serial blood samples were collected up to 72 hours after removing the patch and plasma concentrations were determined by high performance liquid chromatography. Safety was monitored and the skin irritation potential was assessed. RESULTS: The plasma concentration-time profile during 48 hours showed an exponential increase in both of two patch products. Mean C(max) and AUC(last) values were not statistically different between two patch groups. Mean AUC[0-48h] was lower in Murupe(R) patch group than that in Trast(R) patch group; 806.4 and 1196.5 ng.h/mL. However, the mean AUC[48-120h] value tended to be higher in Murupe(R) patch group, implying more delayed excretion than in Trast(R) patch group; 2724.7 ng.h/mL and 1989.2 ng.h/mL. The overall results of skin irritation potential test showed no clinically significant differences between two patch groups. CONCLUSION: Mean Cmax and AUC(last) values in Murupe(R) patch group were comparable to those in Trast(R) patch group. Murupe(R) patch was safe and well tolerated in healthy male subjects.
Chromatography, Liquid ; Cross-Over Studies ; Humans ; Male ; Musculoskeletal Pain ; Piroxicam ; Plasma ; Skin