1.The Effect of a Proton-pump Inhibitor in Unexplained Chronic Cough Patients.
Joo Youn YANG ; Ho Youn LEE ; Nam Hee KIM ; Youn Seup KIM
Tuberculosis and Respiratory Diseases 2006;61(2):137-142
BACKGROUND: Recent studies have suggested an association between chronic cough and gastroesophageal reflux. Our study aimed to assess the utility of a proton-pump inhibitor in unexplained chronic cough patients. METHODS: Patients with chronic cough of unknown etiology were evaluated using a chest x-ray, methacholine challenge test, and an empirical trial of postnasal drip therapy. After excluding other potential causes of the cough, forty patients were included in the study and treated for 8 weeks with a proton-pump inhibitor. RESULTS: Eleven and three patients in the first and second 4 weeks were lost to follow-up, leaving twenty-six patients finally included in the study. Of these patients, two were unimproved, eight partially responded to the proton-pump inhibitor and sixteen responded completely after the 8 week treatment. CONCLUSION: We suggest that empirical treatment with a proton pump inhibitor in all patients with persistent cough, which is not secondary to asthma or postnasal drip syndrome, represents a practical and simple approach to this ailment.
Asthma
;
Cough*
;
Gastroesophageal Reflux
;
Humans
;
Lost to Follow-Up
;
Methacholine Chloride
;
Proton Pumps
;
Thorax
2.Detection of the anti-neural antibodies in the sera of leprosy patients.
Joo Young PARK ; Jung Koo YOUN ; Sang Nae CHO ; Woo Ick YANG ; Choon Myung KOH
Journal of the Korean Society for Microbiology 1992;27(3):239-251
No abstract available.
Antibodies*
;
Humans
;
Leprosy*
3.A 6 year experience with the St. Jude Medical cardiac valve prosthesis.
Kwang Hyun CHO ; Youn Ho WHANG ; Yang Haeng LEE ; Shin Hyun JUNG ; Kang Joo CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(3):296-306
No abstract available.
Heart Valve Prosthesis*
;
Heart Valves*
4.Juvenile Granulosa Cell Tumor Arising in Undescended Testis: A case report.
So Ya PAIK ; Hae Youn KANG ; Jae Ho HAN ; Woo Ick YANG ; Seok Joo HAN
Korean Journal of Pathology 1999;33(5):376-379
Juvenile granulosa cell tumor is rare but one of the common congenital testicular neoplasms. Although histological features are typical of its ovarian counterpart, testicular juvenile granulosa cell tumor has a distinctly different clinical presentation. We report a case of juvenile granulosa cell tumor arising in the cryptochid testis of a 4-day-old newborn. A 6 5 5 cm sized multilocular cyst containing thick, mucinous fluid was found in the peritoneal cavity. The external surface of the cyst was smooth and the septae were relatively thin. The cyst consisted of numerous mucin-filled, cystic follicles lined by cells having vacuolated cytoplasm and round to oval dark nuclei without grooves. Cells resembling granulosa cells of an ovarian follicle were also observed in the intervening stroma forming irregular solid nests.
Cryptorchidism*
;
Cytoplasm
;
Female
;
Granulosa Cell Tumor*
;
Granulosa Cells*
;
Humans
;
Infant, Newborn
;
Male
;
Mucins
;
Ovarian Follicle
;
Peritoneal Cavity
;
Testicular Neoplasms
;
Testis
5.Intra-abdominal Angiosarcomatosis Induced by Irradiation.
Hee Jin CHANG ; Youn Joo KIM ; Sung Eun YANG ; Sung Sook PAENG ; Jung Il SUH
Korean Journal of Pathology 1997;31(3):269-274
Therapeutic irradiation can induce angiosarcoma. Radiation-induced angiosarcoma constitutes 20% of all angiosarcomas. Although its common site of origin is the skin and subcutaneous tissue, it rarely arises in small or large bowels with a presentation as multifocal abdominal angiosarcomatosis. We report a case of intra-abdominal angiosarcomatosis involving the jejunum, ileum, transverse colon, mesentery and right ovary in a 63-year-old female. It developed 10 years after therapeutic irradiation for squamous cell carcinoma of uterine cervix. She developed panperitonitis due to intestinal perforation. She died from sepsis 3 days after segmental resection of the small bowel and right oophorectomy. We reviewed the previously reported cases and describe the clinicopathologic features of this tumor.
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Colon, Transverse
;
Female
;
Hemangiosarcoma
;
Humans
;
Ileum
;
Intestinal Perforation
;
Jejunum
;
Mesentery
;
Middle Aged
;
Ovariectomy
;
Ovary
;
Sepsis
;
Skin
;
Subcutaneous Tissue
6.Clinical review about corrective surgery of tetralogy of Fallot.
Kwang Hyun CHO ; Youn Ho WHANG ; Yang Haeng LEE ; Jong Weon PARK ; Shin Hyun JUNG ; Kang Joo CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(7):674-684
No abstract available.
Tetralogy of Fallot*
7.Treatment Effect of Tranexamic Acid in Plasma D-dimer Level Elevated Anti-histamine Resistant Chronic Urticaria Patients.
Ji Young JUN ; Ji Hye PARK ; Jong Hee LEE ; Dong Youn LEE ; Joo Heung LEE ; Jun Mo YANG
Korean Journal of Dermatology 2017;55(9):628-629
No abstract available.
Humans
;
Plasma*
;
Tranexamic Acid*
;
Urticaria*
8.Clinical experiences of open heart surgery.
Kwang Hyun CHO ; Youn Ho HWANG ; Yang Haeng LEE ; Ji Yoon RYOO ; Kang Joo CHOI ; Sang Jin LEE ; Sang Gwon LEE ; Yang Won KIM ; Yong Gil CHO ; Youn Kyu KIM ; Suk Chul CHOI ; Young Whan SO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(4):282-293
No abstract available.
Heart*
;
Thoracic Surgery*
9.Clinical Effectiveness of Laryngeal Mask Airway ProSeal(TM), Laryngeal Tube and PAxpressTM as a Supraglottic Airway.
In Young HUH ; Youn Joo LIM ; Yoon Kyung LEE ; Hong Seuk YANG
Korean Journal of Anesthesiology 2005;48(3):253-258
BACKGROUND: Supraglottic airway devices can be used to maintain stable hemodynamics during intubation, to secure a difficult airway and to administer muscle relaxants at reduced levels for brief operation. We investigated the insertion success rates, hemodynamic stabilities after insertion, intraoperative ventilatory parameters, and postoperative laryngopharyngeal discomforts of three supraglottic airway devices: the ProSealTM laryngeal mask airway (PLMA), the laryngeal tube (LT), and the PAxpressTM (PAX). METHODS: After induction with thiopental 5 mg/kg with fentanyl 1microgram/kg and rocuronuim 0.6 mg/kg as muscle relaxants, manual control ventilation was done with N2O : O2 (1 : 1) and sevoflurane 5-6 vol% for 2 minutes. The supraglottic airway devices were inserted into 94 adult ASA physical status I and II patients. Unblinded observers collected the intraoperative data, and blinded observers collected the postoperative data. RESULTS: The success rates of first-attempts were similar (PLMA: 96.9%, LT: 93.1%, PAX: 96.8%). The time to achieve effective ventilation was shorten for PLMA. Peak inspiratory pressure (PIP) was significant higher for PAX than PLMA. Cuff pressure significantly increased in LT at 60 and 90 minutes after insertion. LT provided the tightest seal for positive ventilation. The incidence of blood-tinged and sore throat was highest for PAX. CONCLUSIONS: These three supraglottic airway devices can be used successfully and effectively without gastric insufflation. We suspected that the incidences of airway complications were proportional to PIP and cuff pressure and that they are dependent upon insertion skill.
Adult
;
Fentanyl
;
Hemodynamics
;
Humans
;
Incidence
;
Insufflation
;
Intubation
;
Laryngeal Masks*
;
Pharyngitis
;
Thiopental
;
Ventilation
10.The Usefulness of Serum S-100B Protein and Neuron-Specific Enolase as a Screening Test for Making the Differential Diagnosis of Patients with Non-Traumatic Altered Mentality.
Young Mo AN ; Yong Su LIM ; Jae Kwang KIM ; Jin Joo KIM ; Hyuk Jun YANG ; Seong Youn HWANG
Journal of the Korean Society of Emergency Medicine 2009;20(1):101-107
PURPOSE: There are so many causes of an altered mental status, including acute stroke and nonorganic causes. Making the differential diagnosis and the diagnostic approach for cases with an altered mental status represent a challenge to all emergency physicians. The serum S-100B protein concentration and the neuron-specific enolase (NSE) concentration have been used to evaluate brain damaged patients. We evaluated the usefulness of the serum S-100B protein concentration and the NSE concentration as screening tests for the patients with an altered mentality METHODS: Seventy-eight patients with an altered mentality were included in this prospective study. The patients were divided in two groups. One was the acute stroke group and the other was the non-organic cause group. We analyzed the serum S-100B protein and NSE concentrations of the two groups. We also assessed the correlation of the serum S-100B protein and NSE concentrations with the clinical and laboratory data of the two groups RESULTS: The serum concentration of S-100B was higher in the acute stroke group (median: 0.376, interquartile range: 0.18-1.05) than that in the nonorganic group (0.123, 0.087-0.307, p=0.000). The NSE level was also higher in the acute stroke group (median: 19.12, interquartile range: 14.42-27.19) than that in the non-organic group (13.71, 10.48-19.29, p=0.002). To differentiate the acute stroke group from the non-organic group, the sensitivity and specificity was 81.1% and 61.0%, respectively, at a cutoff value for the serum S-100B protein concentration of 0.14 microgram/L, and these were 81.1% and 51.2%, respectively, at a cutoff value for the serum NSE concentration of 13.71 microgram/L CONCLUSION: Our study suggests that the serum S-100B protein and NSE concentrations may be useful as screening markers for differentiating acute stroke from non-organic causes. However, further studies are needed to evaluate the relationship between the two proteins and the various diseases that have possibility to alter patients' mental status before these two proteins can be used clinically as screening tests.
Brain
;
Diagnosis, Differential
;
Emergencies
;
Humans
;
Mass Screening
;
Mentally Ill Persons
;
Nerve Growth Factors
;
Phosphopyruvate Hydratase
;
Prospective Studies
;
Proteins
;
S100 Proteins
;
Sensitivity and Specificity
;
Stroke