2.Tinea pedis in garbage workers.
Jeong Aee KIM ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1992;30(3):340-346
Tinea pedis is frequently found in people with poor personal hygiene and in hot, humid environments. The authors investigated the clinical, epidemiological, and mycological characteristics of tinea pedis in 170 garbage workers(166 males and 4 females) employed in a garbage plant in Seoul, Korea. 40 were clerical workers and 130 were field workers. Tinea pedis was found in 134 with a prevalence rate of 78.8%. Of those 134, 61(45.5%) also had onychomycosis. The prevalence of tinea pedis increased with age and the period working in garbage plant. However, there was no difference in the prevalence of tinea pedis between clerical workers and field workers, mitigating against the conclusion that their tinea pedis may be of occupational origin. Clinically tinea pedis was classified into 4 types ; interdigital (41.8%), vesicular(23.1%), dry squamous(22.4%), and mixed(12.7%). KOH smear positivity and culture positivity was related to clinical types of the lesion the lowest in the interdigital type. In the interdigital type, the etiology of nonmycotic lesions could not be identified. Negative fungal cultures could have been due to secondary bacterial infections. 63 strains of dermatophytes were isolated; 54 strains of Trichophyton rubrem(85.7%), 8 strains of Trichophyton mentagrophytes(12.7%) and 1 mixed infection of T. rubrum and T. mentagrophytes. T. mentagrophytes was isolated only from the vesicular lesions. 8 strains of yeast forms, positive in KOH smears and yielding pure colonies, were also isolated, and repeated mycologic examination yielded the same results. Among them, at least 4 cases of Trichosporon beigelii, and 1 case of Candida parapsilosis were considered to be of pathogenic significance.
Arthrodermataceae
;
Bacterial Infections
;
Candida
;
Coinfection
;
Garbage*
;
Health Personnel
;
Humans
;
Hygiene
;
Korea
;
Male
;
Onychomycosis
;
Plants
;
Prevalence
;
Seoul
;
Tinea Pedis*
;
Tinea*
;
Trichophyton
;
Trichosporon
;
Yeasts
3.An Evaluation of Sunscreen Efficacy Using Mouse Ear Swelling Reaction.
Joo Hyun CHOI ; Jai Il YOUN ; Ai Young LEE ; Jeong Aee KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1990;28(4):419-424
This study was undertaken to investigate the efficacy of 5% PABA cream using mouse ear swelling reaction(ESR). Mice were exposed to 100mJ/cm of UVB, five times a week for four weeks, on the both ventral aspect of the ear, with application of 5% PABA cream on the right ear. The results were as follows : 1. The intensity of ear swelling reaction of 5% PABA protected group was reduced greater than unproteeted group after the first 3 days of UUR. 2. The intensity of ear swelling reached at peak after 1 week of the ultraviolet radiation. Thereafter it has decreased gradually the following 4 weeks. The difference of ear swelling between the two groups was the greatest after 1 week, and the sunscreening efficacy of 5% PABA cream has remained persisted for 4 weeks. 3. The number of mice which have shown severe inflarnmatory response after ultravioiet radiation was more in unprotected group than that in 5% PABA protected group. 4. Determination of mouse ESR is considered a good method for the evaluation of longterm efficacy of sunscreen preparation.
4-Aminobenzoic Acid
;
Animals
;
Ear*
;
Mice*
4.Studies on the relationship between cell proliforation and human cytomegalovirus multiplication: effect of papaverine and methotrexate.
Youn Jeong NAM ; Jae In LEE ; Yong Hoon JIE ; Chan Hee LEE
Journal of the Korean Society of Virology 1991;21(2):193-200
No abstract available.
Cytomegalovirus*
;
Humans*
;
Methotrexate*
;
Papaverine*
5.An analysis of the results of periodic health examination.
Hyung Yune KANG ; Moon Jeong KIM ; Sang Wha LEE ; Hye Ree LEE ; Bang Bu YOUN
Journal of the Korean Academy of Family Medicine 1991;12(7):46-51
No abstract available.
6.An analysis of the results of periodic health examination.
Hyung Yune KANG ; Moon Jeong KIM ; Sang Wha LEE ; Hye Ree LEE ; Bang Bu YOUN
Journal of the Korean Academy of Family Medicine 1991;12(7):46-51
No abstract available.
7.Expression of the S Genome Segment of Hantaan 76-118 in E. coli: Evaluation of Antigenicity of the capsid Protein.
Yun Tai LEE ; Bo Kyung YUN ; Jeong Joong YOON ; Kyoung Won YOUN ; Kyung Hee LEE
Journal of Bacteriology and Virology 2001;31(2):187-192
No abstract available.
Capsid Proteins*
;
Capsid*
;
Genome*
8.Cutaneous Leiomyoma of the Nipple in a Male.
Jeong Joon OH ; Jae Hong PARK ; Dong Youn LEE ; Eil Soo LEE
Annals of Dermatology 2004;16(1):16-18
Cutaneous leiomyoma is a benign tnmor originating from smooth muscle fibers which are derived from arrector pili muscle, media of blood vessels and dartoic muscle of scrotum, vulvar, or nipple. It is classified into 3 types according to the site of origin, namely pilar leiomyoma, angioleiomyoma and genital leiomyoma. Leiomyoma of the nipple is the less kquent type of cutaneous leiomyoma. We report a case of cutaneous leiomyoma on the nipple in a 53-year-old man.
Angiomyoma
;
Blood Vessels
;
Humans
;
Leiomyoma*
;
Male*
;
Middle Aged
;
Muscle, Smooth
;
Nipples*
;
Scrotum
9.The Pretreatment Effects of Morphine, Propofol, Atropine, and Midazolam on Fentanyl Cough Response.
Jeong Yeon HONG ; Hae Keum KIL ; Won Oak KIM ; Youn Woo LEE ; Chang Ho KIM
Korean Journal of Anesthesiology 1997;33(4):711-715
BACKGROUND: The afferent and efferent pathways of fentanyl cough response (FCR) and central organization are poorly understood at present. The aim of this study was to investigate the pretreatment effects of morphine, propofol, atropine, and midazolam on FCR. METHOD: The 120 healthy patients were randomly assigned to six equal pretreatment groups. They received 2ug/kg fentanyl rapidly through a peripheral venous catheter. The patients in each group were pretreated before the time necessary for peak plasma levels with different drugs as follows: group 1, no premedication; group 2, morphine 0.05 mg/kg iv; group 3, morphine 0.05 mg/kg iv naloxone 0.01mg/kg iv; group 4, propofol 0.5 mg/kg iv; group 5, atropine 0.01 mg/kg iv; group 6, midazolam 0.05 mg/kg iv. The patients were observed for any coughing or side effects, including oxygen desaturation, bronchoconstriction, chest wall rigidity and seizure. RESULT: 40% of patients in group 1 (control) had a cough response to fentanyl. Group 2 (morphine) and group 3 (morphine naloxone) showed a reduced FCR of 10%. The incidence of coughing was 60% of the patients in group 4 (propofol), 30% in group 5 (atropine), and 40% in group 6 (midazolam). These were not statistically significant. CONCLUSION: FCR is not altered by pretreatment with propofol, atropine, or midazolam, but morphine inhibits cough response and this antitussive effect was not antagonized by naloxone.
Atropine*
;
Bronchoconstriction
;
Catheters
;
Cough*
;
Efferent Pathways
;
Fentanyl*
;
Humans
;
Incidence
;
Midazolam*
;
Morphine*
;
Naloxone
;
Oxygen
;
Plasma
;
Premedication
;
Propofol*
;
Seizures
;
Thoracic Wall
10.Effect of Recombinant Human Growth Hormone on Lipid peroxidation and Plasma TNF-alpha and IL-6 Following Thermal Injury in Rats.
Gil Joon SUH ; Joong Eui LEE ; Yeon Kwon JEONG ; Yeo Kyu YOUN ; Seung Keun OH
Journal of the Korean Society of Emergency Medicine 1997;8(2):137-149
Inflammatory mediators, such as oxidants, TNF-alpha, and IL-6, play a major role in the systemic response to bum injury It has been known that a continuing inflammatory response cause a sepsis and subsequent multiple organ failure. Recent studies have shown that burn patients receiving recombinant human growth hormone(rhGH) therapy have an improvement of the general condition, but the mechanism by which rhGH exerts its effects has not been clearly understood. The aim of this study was to evaluate the effect of rhGH on the early bum injury. Female Sprague-Dawley rats were divided into four groups : control group, bum group, burn plus rhGH treated group, and rhGH only treated group. Animals were killed at 30min., 3, 6, 24, and 48 hours after treatment. Histology and biochemical changes including malondialdehyde(MDA) content, tissue reduced glutathione(GSH) and catalase activity in the lung and liver, and plasma TNF-alpha and IL-6 levels were examined. Lung histology in the bum plus rhGH treated group showed decreased inflammtory response such as neutrophil and lymphocyte infiltrations, interstitial thickening, and edema compared with the bum group. Liver histology in the bum group revealed mild neutrophil and lymphocyte infiltrations, vacuolization .of hepatocytes, disrupted lobular structures, and dilated sinusoids. But liver histology of the bum plus rhGH was similar to control group. Lung and liver MDA in the burn plus rhGH and rhGH only treated groups were decreased with time compared with the burn group. Lung and liver GSH and catalase activities in the bum plus rhGH and GH only treated groups remained significantly increased compared with the bum group for the 48-hours period. Plasma TNF-alpha levels in the bum group remained elevated for the 48-hours period compared with the bum plus rhGH and rhGH only treated groups. Plasma IL-6 levels in the burn group were significantly increased only at first compared with the bum plus rhGH and rhGH only treated groups. These results suggested that rhGH showed inhibitory effects on the inflammatory cell infiltration and lipid peroxidation in the lung and liver after bum injury. Increased GSH levels and catalase activities seemed to be associated with the antioxidant effect of rhGH. But the inhibitory effect of rhGH on plasma TNF- and R-6 levels was not clearly demonstrated.
Animals
;
Antioxidants
;
Burns
;
Catalase
;
Edema
;
Female
;
Hepatocytes
;
Human Growth Hormone*
;
Humans*
;
Interleukin-6*
;
Lipid Peroxidation*
;
Liver
;
Lung
;
Lymphocytes
;
Multiple Organ Failure
;
Neutrophils
;
Oxidants
;
Plasma*
;
Rats*
;
Rats, Sprague-Dawley
;
Sepsis
;
Tumor Necrosis Factor-alpha*