Objective To study and analysis the MRI characteristics of common intracranial ring enhanced lesions.Methods MRI studies of 32 cases intracranial ring enhanced lesions were reviewed retrospectively,all cases were confirmed by surgery or pathology and anti-inflammatory treatment.Results Among 32 cases of Intracraninal ring enhaneed lesions included 12 glioblastomas,10 metastases,5 brain abscesses,2 craniophrayngiomas,1 tuberculosis granuloma,1 neurocysticercose,1 multiple sclerosis.On the whole,the malignant tumors displayed obviously heterogeneous thickness of the walls,especially the inner walls were uneven and coarse,While the non-tumor lesions demonstrated,regular shapers,smooth inner walls and even thickness of the walls.Conclusion Intracranial ring enhanced lesions has a specific MRI finding and can supply important diagnostic value.

In atherosclerosis, chronic inflammatory processes in local diseased areas may lead to the accumulation of reactive oxygen species (ROS). In this study, we devised a highly sensitive H₂O₂-scavenging nano-bionic system loaded with probucol (RPP-PU), to treat atherosclerosis more effectively. The RPP material had high sensitivity to H₂O₂, and the response sensitivity could be reduced from 40 to 10 μmol/L which was close to the lowest concentration of H₂O₂ levels of the pathological environment. RPP-PU delayed the release and prolonged the duration of PU in vivo. In Apolipoprotein E deficient (ApoE^‒/‒) mice, RPP-PU effectively eliminated pathological ROS, reduced the level of lipids and related metabolic enzymes, and significantly decreased the area of vascular plaques and fibers. Our study demonstrated that the H₂O₂-scavenging nano-bionic system could scavenge the abundant ROS in the atherosclerosis lesion, thereby reducing the oxidative stress for treating atherosclerosis and thus achieve the therapeutic goals with atherosclerosis more desirably.