OBJECTIVE To assess the current status of nosocomial infection and antibiotics utilization of the hospital.METHODS The hospital infection rate was investigated,by means of prevalence survey and investigation of bed-side and cases records.RESULTS Of the 1620 surveyed cases,the prevalence rate was 5.49% and the case prevalence rate 5.93%.And the top three infected sites were the lower respiratory tract,upper respiratory tract and urinary tract(48.88%,13.54% and 10.42%,respectively).The total number of antibiotic use was 599 case-times.The incidence of antibiotic use was 36.9%.Of 322 cases,53.76% was intended for active treatment,and 34.56% for preventive regimen.CONCLUSIONS It is necessary to strengthen management of hospital infection and the management of clinical antibiotic usage in some wards.

OBJECTIVE To survey antibiotic use and its rationality in clinical settings. METHODS Randomly selected medical records of 500 patients from Oct to Dec of 2004 were reviewed for retrospective studies.Analysis with regard to drug category combination purpose,therapeatic course,indications and resistance was conducted. RESULTS The incidence of antibiotic use was 98%,31% of which was intended for active treatment,and 69% for preventive regimen;65% of the cases in internal medicine were for active treatment,and 34% for preventive regimen,45% of the cases in surgical use were for active treatment,and 54% were for preventive purposes.The total number of antibiotic use was 539 case-times.In terms of preventive use,single drug comprised 57%,bi-drug therapy 19%,before operations 19%,and local use was 5%.As for active treatment single drug consisted of 49%,two-drugs 27%,three-drugs 7%,and four-drugs 1%,local use accounted for 16%.Fifty five cases of the therapeutic use of antibiotics were reviewed,taking up 28% of the total with 19 positive cases,whose positive rate accounted for 35%. CONCLUSIONS The administration of the reasonable use of antibiotics is a systematic project.

OBJECTIVE To find out the clinic air disinfectant effect and the damage to human body between air aerosol sprayer of hydrogen peroxide and peracetic acid. METHODS New ninety eight sickrooms were randomly disported into two groups. The group of using peracetic acid was a control one. Then the clinic air disinfectant effect and the damage between two groups were observed. RESULTS After thirty minutes, to sample through flat exposure method. The total number of bacteria of two groups reached the third grade of environment eligible standard without pathogenic bacteria being checked. Hydrogen peroxide had not obvious mucous membrane stimulation and hypersusceptible reaction to human body. But peracetic acid had mucous membrane stimulation and hypersusceptible reaction to human body. CONCLUSIONS The air disinfection using aerosol sprayer is still an available method when there are no person in new sickrooms or extended sickrooms. At present, some chemical disinfectant methods that have strong poisonous reactions and pollute environment, such as peracetic acid, have been restricted to be used because of thrill, toxicity to human body and causticity to goods. But the method of dynamic air disinfectant machine that can be used in the situation of ventilation, dust catching, decontaminating, and ultraviolet irradiation, at the same time having someone has became a new idea of air disinfection.

OBJECTIVE To improve the accuracy of the radiant intensity detection of ultraviolet lamp and ensure its disinfection effect.METHODS At the different time after use of the ultraviolet lamp,its radiant intensity was measured by using the luminometer,and estimated.RESULTS If the ultraviolet lamp with good uality and worked one hour each day,with detected intensity ≥90 ?W/cm2,it could be used one year continuously,when ≥80 ?W/cm2,it could be used 6 months continuously,and when 80-75 ?W/cm2,it could be used 1 month continuously.The lump's detected intensity must be exceeded over 70 ?W/cm2.CONCLUSIONS The method that detecting the radiant intensity of ultraviolet lamp in scheduled time and consulting the used time of lump is viable.The method is real,simple,convenient and easy manipulated and ensures the effectiveness of disinfection by using ultraviolet lamp.

Objective To study a new closed medical waste transportation vehicle. Methods The carriage,doors,floor drains pipes and spray system are all used in stainless steel materials with made through the welding. Results The vehicle can protect medical staffs from pollution of medical waste and enhance occupational health protection for staff. Conclusion The vehicle is closed that has the function of 360? spray cleaning and disinfection system,and it many advantages such as the use of safe,effective,energy saving,convenient and development application.

BACKGROUND:Denis B thoracolumbar burst fractures are common spinal injury and may be involved in the upper end plate injury. Fracture reduction and pedicle screw fixation are used to repair above injury. This scheme can effectively achieve the aim of correcting deformity, but the trabecular bone after crushing cannot be fuly recovered. OBJECTIVE:To observe the repair effect of fracture reduction and pedicle screw fixation + artificial bone graft in vertebral body on Denis B thoracolumbar burst fracture, and compare with fracture reduction and pedicle screw fixation alone. METHODS:Clinical data of 70 cases of Denis B thoracolumbar burst fractures, who were treated in the Department of Orthopedics, Zhangjiagang Aoyang Hospital from January 2012 to December 2014, were retrospectively analyzed. According to repair scheme, they were equaly divided into two groups. Patients in the control group received fracture reduction and pedicle screw fixation. Patients in the observation group received fracture reduction and pedicle screw fixation + artificial bone graft in vertebral body. Oswsetry Disability Index, height of anterior border of injured vertebral body, lower back pain visual analogue scale and vertebral kyphosis Cobb’s angle were compared and observed between the two groups before repair, 1 week, 3 and 6 months after repair. RESULTS AND CONCLUSION:No significant difference in Visual Analogue Scale was detected at 1 week, 3 and 6 months after repair between the observation and control groups (P > 0.05). Oswsetry Disability Index was significantly lower in the observation group than in the control group (P < 0.05). No significant difference in the height of anterior border of injured vertebral body was detected between the observation and control groups (P > 0.05). Cobb’s angle was significantly lower in the observation group than in the control group (P < 0.05). These findings suggest that fracture reduction and pedicle screw fixation + artificial bone graft in vertebral body obtained good repair effects on Denis B thoracolumbar burst fracture, not only effectively corrected Cobb’s angle and the height of anterior border of injured vertebral body, but also helped to restore normal spinal loads by filing bone in the injured vertebral body.

OBJECTIVE To discuss the reasons of causing mistakes in the nosocomial infection reports.METHODS We collected 183 cases with inaccurate reports and analyzed them by the prospective method.RESULTS The major reasons of causing the inaccurate nosocomial infection reports were the ill-defined infection time,inaccurate diagnostic standard,and the lack of clinic training.CONCLUSIONS It can reduce the inaccurate nosocomial infection reports,advance the level of nosocomical infection diagnosis,and improve the work efficiency through special training,in paralleling with the manager of nosocomial infection going deep into sickroom and communicating with clinicians.

0.05),while there was difference between length of hospital stay,expense of antibacterial for prevention and total expense of hospitalization(P

This paper presents the configuration defect of HITACHI 7080 biochemical analyzer and the trouble from it.The resolvent is also put forward.

Objective To probe the association between possible single nucleotide polymorphism (SNP) in the FGB promoter region and idiopathic deep venous thrombosis.Methods A prospective analysis was performed in both IDVT group and control group (120 cases each) followed by a duplex examination using gene sequencing technique and restriction fragment length polymorphism (RFLP) in the promoter region of fibrinogen gene β.Possible SNPs in this region were detected arranged before HardyWeinberg equilibrium test and Linkage disequilibrium (LD) analyses.Ultimately,we compared the genotype frequencies between the two groups and undertook a multiple Logistic regression.Results Six kinds of SNPs were determined in the promoter region of β-fibrinogen gene:-148C/T,-249C/T,-455G/A,-854G/A,-993C/T and-1420G/A.A stronger linkage disequilibrium was confirmed between-993C/T and -455G/A (r2 =0.699) ;-993C/T and-148C/T (r2 =0.509) ;-455G/A and-148C/T (r2 =0.556).Statistical differences of genotype frequencies between two groups were observed in-148C/T,-249C/T,-455G/A and-1420G/A polymorphisms (all P ＜ 0.05).Conclusions The risk of IDVT was 4.579 times higher with every 1 g/L increase of fibrinogen concentration.Allele-148T,-455G and-1420A are IDVT risk factors.-993C/T may indirectly affect IDVT through linkage disequilibrium with-455G/A and-148C/T.