Objective:To observe the effect of Jieyu Anmian prescription of Chinese medicine foot bath on gastrointestinal function in patients with digestive system tumor during perioperative period.Methods:A total of 130 patients with digestive system tumors were chosen from January 2019 to March 2020 for the first time visits to the first hospital of lanzhou university for surgical treatment, 15 cases lost follow-up, and the rest 115 cases of patients were divided into the experimental group (59 cases) and the control group (56 cases) according to random number table method. The control group using conventional care method, the experimental group was treated with Jieyu Anmian washing formula on the basis of routine nursing care for 10 days. During the foot bath, the recovery of gastrointestinal function, the time of the first exhaust and defecation, the length of stay, the cost of stay and the satisfaction of patients were compared between the two groups.Results:The recovery time of bowel sounds, anal exhaust time and first defecation time of the experimental group were all earlier than those of the control group (16.21±11.81) h, (19.64±12.40) h and (41.98 ±19.16) h, respectively, while those of the control group were (27.34±31.47) h, (35.81±18.26) h and (34.47±16.41) h, respectively. The differences were statistically significant ( t value was -2.41, -5.33, 2.17, P< 0.05). The results of the survey of patient satisfaction showed that the experimental group was superior to the control group, with 97.47 ± 4.37 in the experimental group and 94.19 ± 3.29 in the control group, with statistically significant differences ( t value was 3.89, P<0.01). The satisfaction of doctors in the experimental group was 97.41 ± 6.25 and 94.21±5.91 in the control group, with statistically significant difference ( t value was 3.95, P<0.05). The satisfaction of nurses in the experimental group was 97.58 ± 4.53 and 93.85±5.23 in the control group, and the difference was statistically significant ( t value was 4.12, P<0.05). There was no significant difference between the two groups in terms of length of stay and hospitalization expenses ( P>0.05). Conclusions:Jieyuanmian prescription of Chinese medicine foot bath can promote the recovery of gastrointestinal function, promote the exhaust and defecation, and improve the satisfaction of patients and nurses.

Objective To evaluate clinical efficacy and safety of levornidazole in the treatment of pelvic anaerobic infections. Methods A multicenter randomized controlled clinical study was conducted to evaluate clinical efficacy and safety of levornidazole. One hundred and fourty-three patients with pelvic anaerobic bacteria infection were classified into 70 cases treated by levornidazole in study group and 73 cases treated by Ornidazole in control group. Those patients in two groups were both administered at a dose of 0. 5 g twice daily for 5 - 7 days. The rate of clinical efficacy, bacteria clearance and adverse effect were recorded and compared between two groups. Results At the endpoint, the rate of clinical efficacy were 80% (56/70) in study group and 81% (59/73) in control group, which did not reach significant difference (P＞0. 05). The rate of bacteria clearance were 97% (36/37) in study group and 92% (22/24) in control group, which also did not reach significant difference(P ＞0. 05). The rate of adverse reaction of 3% (20/70) in study group was significantly lower than 22% ( 16/73 ) in control group ( P ＜ 0. 05 ). Conclusion It is effective and safe to treat pelvic anaerobic infections with levornidazole and sodium chloride injection.

Objective: To investigate the effection of 10% glucose on laparoscopic cholecystectomy. Methods: Including 82 cases in patients undergoing laparoscopic cholecystectomy from June 2018 to November 2018 in the First Hospital of Lanzhou University. They were divided into the experimental group(40 cases) and the control group (42 cases) according to admission time. The control group used conventional nursing measures, fast day after 0:00. The experimental group took orally 400 ml 10% glucose solution on the night before surgery, 10% glucose 100 ml at 6:00 on the day. And then the perioperative safety, comfort and hospital satisfaction were observed. Results: No postoperative nausea and vomiting and complications occurred in the two groups. The perioperative satisfaction score of the experimental group was greater than the control group, which was 94.00±3.08 and 80.00±11.54 points, respectively, and the difference was statistically significant (t=3.45, P<0.01). The VAS scores of thirst, hunger, fatigue and anxiety in the experimental group were 2.97±3.55, 1.50±0.57, 2.50±1.00, 2.25±0.96, respectively, which were lower than those in the control group (3.55±2.98, 2.25±0.50, 5.50±0.57, 5.25±1.89), and the differences were statistically significant (t= 2.83-5.19, P<0.01 or 0.05). The VAS scores of thirst, hunger and fatigue in the experimental group were 3.60±1.00, 3.50±0.56, 2.75±1.50, respectively, 4 h after surgery, which were lower than those in the control group (7.00±0.58, 4.75 ±1.25, 5.75±0.50), with statistically significant differences (t=5.00, 3.69, 3.79, P<0.05). Compared with preoperative situation, the thirst and hunger degree of the two group both increased after surgery, while the anxiety degree of the control group decreased, and the difference was statistically significant (t=-9.91-5.20, P<0.05 or 0.01). Conclusions Oral administration of 10% glucose solution before laparoscopic cholecystectomy is safe and effective, which can improve perioperative comfort and hospitalization satisfaction of patients.