1.Application of morpheme translation method in english translation of TCM.
Chinese Journal of Integrated Traditional and Western Medicine 2006;26(3):266-268
In this paper, application of morpheme translation method in English translation of TCM was introduced, and its superiorities and limitations were analyzed in order to promote the standardization and improve the confused current status of the English translation of TCM.
Medicine, Chinese Traditional
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Terminology as Topic
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Translations
2.Analysis on variation of hemagglutinin genes of sixteen H9N2 subtype avian influenza viruses isolated in Shandong area.
Li-Li WU ; You-Xiang DIAO ; Xiao-Jun JU ; Chun-Mei YU ; Jing-Teng CUI
Chinese Journal of Virology 2012;28(3):272-277
In order to explore the genetic mutations of the H9N2 subtype avian influenza viruses isolated in Shandong, sixteen avian influenza virus subtype H9N2 were isolated from different areas of Shandong Province. The complete HA fragments of the viruses were amplified by RT-PCR and the sequences were analyzed on homology and heredity evolution after the cloning and sequencing of the products. The results showed that the amino acid motif of cleavage sites for all the sixteen virus in the HA gene were RSSR decrease GLF, which was consistent with the characterization of the LPAIV. Seven to nine potential glycosylation sites were found during the analysis and the receptor binding sites were relatively conservative except the 198 site. The Leucine(L) at the amino acid position 234 in the HA genes of all isolates indicated the potential of binding with SAalpha,2-6 receptor of mammals. Homology analysis showed that the homology of HA nucleotide and amino acid sequences was 96.3%-99.9% and 97.1%-99.6% for different strains. They belonged to a branch of the A/Duck/Hong Kong/Y280/97 in the phylogenetic tree.
Amino Acid Sequence
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Animals
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Birds
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China
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Genetic Variation
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Hemagglutinin Glycoproteins, Influenza Virus
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chemistry
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genetics
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Influenza A Virus, H9N2 Subtype
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chemistry
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classification
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genetics
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isolation & purification
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Influenza in Birds
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virology
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Molecular Sequence Data
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Phylogeny
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Sequence Homology, Amino Acid
3.Prognostic Predictors of Adrenocortical Carcinoma in Adults
Shao-hua LI ; Ju-ying TANG ; Shao-ling ZHANG ; Li-li YOU ; Ke-xu XIANG ; Diao-zhu LIN ; Ying GUO ; Li YAN ; Jian HUANG
Journal of Sun Yat-sen University(Medical Sciences) 2019;40(1):62-69
adrenocorticalcarcinoma;cortisolhypersecretion;hypokalemia;prognosis
【Objective】To analyze the prognostic determinants of adreno cortical carcinoma(ACC)inadults.【Methods】Alladult patients who were admitted to SunYat-sen Memorial Hospital,SunYat-sen University from December 2011 to March 2017 and pathologically diagnosed ACC were included in this study.Thec linical data and preoperative laboratory examinations of those patients were analyzed retrospectively. Overall survival or disease-free survival was calculated and survivalcurves were plotted by Kaplan-Meier and compared by log-rank test. Harzardratios(HRs) with their 95% confidenceintervals(CIs) were calculated by univariate and multivariate Coxregression model.【Results】The study included 20 adult patients with ACC, with a median follow-up of 13months (6~73 months). The mean survival time of those patients was 49.2 months(6~73months),with a 1-year survival rate of 70.0%. The results of multivariate Coxregression analysis revealed that the presense of cortisol hypersecretion(HR=23.60,95%CI:2.49-223.79,P=0.006) and hypokalemia(HR=23.60,95%CI:2.49-223.79,P=0.006)were predictors of poorprognosis of ACC. Moreover,in 18 patients with completely resected ACC,the presense of hypokalemia resulted in a worse disease-free survival.【Conclusion】The presense of cortisol hypersecretion and hypokalemiaare independent risk factors associated with poorprognosis of ACC in adults.