1.Investigation and analysis of psychological consulting requirement for the hospital staff
Yuezhen QI ; Cheng ZHAO ; Mingjie LIU ; Wei YOU ; Fei YAN
Chinese Journal of Hospital Administration 2014;30(6):453-454
Objective To learn the psychological needs of the hospital staff in terms of their life,medical care and psychological health.Methods 2910 hospital staff were interviewed with questionnaires and the outcomes analyzed with x2 test and descriptive analysis.Results 96.9%of the surveyed found themselves in need of psychological counseling; considerable consulting needs of the staff; most of them turn to friends to complain instead of their leaders.Conclusion The psychological counseling should be enhanced to build effective communication channels and ease stress of the staff.
2.Removal Algorithm of Power Line Interference in Electrocardiogram Based on Morphological Component Analysis and Ensemble Empirical Mode Decomposition.
Wei ZHAO ; Shixiao XIAO ; Baocan ZHANG ; Xiaojing HUANG ; Rongyi YOU
Journal of Biomedical Engineering 2015;32(6):1179-1184
Electrocardiogram (ECG) signals are susceptible to be disturbed by 50 Hz power line interference (PLI) in the process of acquisition and conversion. This paper, therefore, proposes a novel PLI removal algorithm based on morphological component analysis (MCA) and ensemble empirical mode decomposition (EEMD). Firstly, according to the morphological differences in ECG waveform characteristics, the noisy ECG signal was decomposed into the mutated component, the smooth component and the residual component by MCA. Secondly, intrinsic mode functions (IMF) of PLI was filtered. The noise suppression rate (NSR) and the signal distortion ratio (SDR) were used to evaluate the effect of de-noising algorithm. Finally, the ECG signals were re-constructed. Based on the experimental comparison, it was concluded that the proposed algorithm had better filtering functions than the improved Levkov algorithm, because it could not only effectively filter the PLI, but also have smaller SDR value.
Algorithms
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Electrocardiography
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Humans
5.ACUTE MYOCARDIAL INFARCTION WITH DIABETES MELLITUS: A CLINICAL STUDY OF 89 CASES
Yuanyou ZHAO ; Sirang WANG ; Lianbi YOU ; Lixin WEI
Medical Journal of Chinese People's Liberation Army 1983;0(02):-
Among 941 patients of AMI admitted in the period from Jan 1969 to Jan 1989, 89 cases were complicated with diabetes mellitus (9.5%). The diabetic patients are older than non-diabetic, the occurrence of reinfarction and complications during AMI were more frequent and the mortality was higher incidence of complication of hypertension (69.7%) and hyperlipi-demia(39.3%).The clinical characteristics of AMI in diabetic patients are: higher occurrence of silent myo-cardial infarction and more frequent occurrence of heart failure. Recently, evidences from clinic-pathologic and epidemiologic investigations and experimental studies suggest that diabetes mellitus is associated not only with severe coronary atherosclerosis, but also microangiopathy, disorders in vegetative nervous system, and pathology of the myocardium. Therefore effective measures for prevention and treatment of diabetes is very important to decrease the mortality of AMI.
6.Development of the Structures and Characteristics of Microcapsules
Wei-Yan HAN ; You-Xi ZHAO ; Ping GONG ;
China Biotechnology 2006;0(01):-
Microcapsule technology recently has been applicated and developed in pharmaceutical,chemical,food and so on.The achievments have been obtained on the novel technics of microcapsulation,analytical methods of microcapsule characteristics,and methods of characterization for the appearance and porous structures of microcapsules.The novel developments on the structure and property of microcapsules were reviewed.
7.Behavior problems and family factors in children of off-farm workers of Shanghai
Baolong ZHAO ; Wei JI ; Zhimin ZHAO ; Wenhong CHENG ; Guangping LI ; Meina YOU ; Yong ZHAO ; Min LI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(12):1073-1076
Objective To survey prevalence of behavior problems in children of off-farm workers and effects of family factors on children' s behavior problems.Methods The study was done in the whole 7 schools for off-farm workers' children in Shanghai Baoshan district,including all 3 ~ 6 grades students of primary school and 1 ~3 grades students of junior high school.Totally 4350 students finished survey (95.4%).Achenbach' s child behavior checklist ( CBCL,parent' s version) and general family questionnaire were used.Results ( 1 ) Prevalence of behavior problems in children was 11.2% ; 12.8% 12 ~ 16 years children had behavior problems( 14.7%boys and 10.4% girls) ; 11.4% of one-child children had behavior problems compared with that of 11.2% child with siblings children ( x2 =0.038,P > 0.05 ).(2) Total score ( 20.64 ± 17.67 ) and factor scores of thought problems,depressed,hyperactivity,delinquent rule-breaking behavior were higher than those of Chinese norm (P <0.05 or P < 0.01 ) among 6 ~ 11 years boy group.Total score ( 17.23 ± 14.73 ) and scores of thought problems,depressed,social problems,hyperactivity,delinquent rule-breaking behavior were higher than those of Chinese norm (P < 0.01 ) among 6 ~ 11 years girl group.Among 12 ~ 16 years boy group,total score (20.44 ± 19.32) and all factor scores of CBCL were higher than those of Chinese norm(P<0.01 ).Total score ( 17.02 ± 16.72) and scores of immature,delinquent rule-breaking behavior,brutality were higher than those of Chinese norm(P < 0.05 or P <0.01 ) among 6 ~ 11 years girl group.(3)Multi-regression analysis showed that poor parent-child relationship was the most important predict factor for higher score of CBCL among all family risk factors (P < 0.05 ).Conclusion Children of the off-farm workers and their families need special mental health care program.
8.Radiofrequency ablation of cardiac fat pad at right pulmonary vein-atria junction attenuates Bezold-Jarisch reflex in canine
Wei ZHAO ; De-Ning LIAO ; Yang XIA ; Xue ZHAO ; Jia-You ZHANG ; Xing-Jian GU ;
Academic Journal of Second Military Medical University 1999;0(12):-
Objective:To observe the influence of radiofrequency catheter ablation of the fat pad at the right pulmonary vein- atria junction(RPV fat pad)on Bezold-Jarisch reflex(BJR)induced by veratridine in canine.Methods:Ten mongrel dogs were anesthetized and their chest were opened through a right thoracotomy to expose the RPV fat pad.Veratridine was injected into the left ventricle at bolus doses of 10?g/kg through a catheter to induce BJR.The sinus cycle length(SCL),systolic arterial pressure(SAP),diastolic arterial pressure(DAP),mean arterial pressure(MAP),left ventricle systolic pressure(LVSP), left ventricle diastolic pressure(LVDP)and mean left ventricle pressure(MLVP)were measured under the baseline and after ablation of the RPV fat pad;the changes of the above parameters(?SCL,?SAP,?DAP,?MAP,?LVSP,?LVDP,and?MLVP)were calculated.Then the same dose of veratridine was injected under the pad after ablation and the changes of the a- bove parameters were observed.Results:BJR was successfully induced in the 8 animals;the animals has prolonged sinus cycle length(SCL)and decreased MAP and MLVP.After ablation,the prolongation of SCL after injection of veratridine was markedly reduced([229.2?92.3]ms vs[39.3?14.1]ms,P
9.Allogeneic bone marrow derived mesenchymal stem cells transplantation leads to stable chimerism and induces donor specific tolerance
Weimin DENG ; Qin HAN ; Shengguo YOU ; Wei ZHANG ; Wei GE ; Changhong LI ; Hongye DENG ; Chunhua ZHAO
Chinese Journal of Laboratory Medicine 2003;0(08):-
Objective To investigate the possibility of immune tole rance induced by bone marrow-derived mesenchymal stem cells in allogeneic organ transplantation. Methods Allogeneic bone marrow-derived mesenchymal stem cells and syngeneic bone marrow cells were cotransplanted to lethally irradiated female C57BL/6 recipient mice. FACS was used to analyze the chimerism 150 days later. Mixed lymphocyte reaction and ConA induced proliferation test were performed to evaluate proliferative activity of mice spleen cells in cell-transplanted group. Skin transplantation test was done to observe immune response of cell-transplanted group mice against organ graft from donor mice. Results About 5 97% donor T cells were detected in splenocytes of cell-transplanted group mice. MLR showed that mean SI of cell-transplanted group mice was 1.79, and that of untreated group mice was 7 28. ConA induced proliferation test showed that mean SI of cell-transplanted group mice was 31 92; and that of untreated group mice was 34 99. Mean survival time of donor-derived skin graft in cell-transplanted group mice was more than 90 days; and that in untreated group mice was 8 days. Conclusion Our results showed for the first time that induction of stable mixed hematopoietic chimerism after allogeneic bone marrow derived mesenchymal stem cells transplantation lead to stable donor-specific tolerance in allogeneic host and skin graft survival from donor mice.
10.Protective effects of yanggan lidan granules on carbon tetrachloride-induced liver damage in mice
Shengfu YOU ; Peiyong ZHENG ; Guang JI ; Huafeng WEI ; Jie ZHAO ; Peiting ZHU
Journal of Integrative Medicine 2005;3(6):470-2
OBJECTIVE: To observe the protective effects of Yanggan Lidan Granules (YGLDG) on carbon tetrachloride (CCl(4))-induced liver damage in mice and to find out its mechanism. METHODS: A model of chronic liver damage was established in mice by intraperitoneal injection of CCl(4). After three weeks, those model mice were treated with low-, medium-, high-dose YGLDG, Danning Tablets and bifendate respectively for four weeks. Then the levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST), as well as the contents of superoxide dismutase (SOD) and malondialdehyde (MDA) in liver tissues were detected. RESULTS: YGLDG could significantly reduce the levels of serum ALT and AST in model mice, and the content of MDA was obviously decreased while the content of SOD was increased in liver tissue. CONCLUSION: The therapeutic effect of YGLDG on mice with CCl(4)-induced liver damage is to relieve the seriousness of liver damage, and its mechanism may relate to reducing peroxidation activity in liver tissue.