1.The incidences of autoantibodies after in vivo administration of interferon-gamma.
Myung Shik LEE ; Seong Hoe PARK ; Yong Seong KIM ; Noe Kyeong KIM ; Think You KIM
Journal of Korean Society of Endocrinology 1991;6(3):227-231
No abstract available.
Autoantibodies*
;
Incidence*
;
Interferon-gamma*
2.Surgical decompression of thyrotoxic exophthalmos: a case report.
Hyeon Ok KIM ; Seong Hoon JEONG ; Seong Jong YOU ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(4):849-858
No abstract available.
Decompression, Surgical*
;
Exophthalmos*
3.The Relationship between ST-T Electrical Alternans on EKG and Ventricular Arrhythmia.
You Hong KIM ; Seong Yun O ; Dal Soo LIM ; Dae Seong HYUN ; Sung Gug CHANG ; Young Hoon YOU ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Korean Circulation Journal 1990;20(3):305-314
In order to observe the development of ventricular arrhythmia during regional myocardial ischemia and reperfusion, especially under the presence or absence of ST-T electrical alternans on epicardial EKG. The proximal left descending coronary artery(LAD) was ligated for 20 minutes and then reperfused suddenly in twenty-three cats. Standard lead EKG(Lead??, chest lead EKG and epicardial lead EKG were recorded simultaneously during the occlusion and reperfusion respectively. During the ligation of LAD, STEA was observed in thirteen cats(56.5%). In occlusion period, the incidence of ventricular tachycardia in STEA positive group was significantly higher than in the negative group(p<0.01) and arrhythmic score was significantly higher(p<0.005) also In the reperfusion period the incidence of vefntricular fibrillation in STEA positive group was significantly higher than in the negative group(p<0.025). But there was the tendency to be higher in arrhythmic score of STEA positive group. There were no differences in heart rate, systolic left ventricular pressure, ST elevation and ST width in both groups. Most forms of ST-T of sinus rhythm before and after development of ventricular premature beat was low form(L). It was concluded that at the presence of STEA on EKG, the incidence of ventricular arrhythmia was more prevalent. So, STEA can be available as a marker of ventricular arrhythmia and prognostic factor.
Animals
;
Arrhythmias, Cardiac*
;
Cardiac Complexes, Premature
;
Cats
;
Electrocardiography*
;
Heart Rate
;
Incidence
;
Ligation
;
Myocardial Ischemia
;
Reperfusion
;
Tachycardia, Ventricular
;
Thorax
;
Ventricular Pressure
4.A case of delayed hemolytic transfusion reaction due to anti-e identified by bromelin treatment.
You Kyoung LEE ; Yeon Sun KIM ; Jee Young AHN ; Hwi Jun KIM ; Seong Gyu HWANG
Korean Journal of Blood Transfusion 1992;3(2):185-189
No abstract available.
Blood Group Incompatibility*
;
Bromelains*
5.A study of effect on human epithelization by topical application of epidermal growth factor.
Hyeon Ok KIM ; Sung Moon CHUNG ; Seong Jong YOU ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(3):509-518
No abstract available.
Epidermal Growth Factor*
;
Humans*
6.Consenital blepharophimosis with family history.
Hyeon Ok KIM ; Kwang Ho LEE ; Sung Moon CHUNG ; Seong Jong YOU ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):1058-1063
No abstract available.
Blepharophimosis*
;
Humans
7.IMMEDIATE CHANGE OF THE TEMPOROMANDIBULAR JOINT SYMPTOMS AFTER EVRO(EXTRAORAL VERTICAL RAMUS OSTEOTOMY) WITHOUT FIXATION IN THE TMJ INTERNAL DERANGEMENT PATIENTS.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1999;25(2):165-171
TMJ internal derangement has been treated by the conservative methods and the surgical methods according to the clinical state. There are several surgical methods for treatment of TMJ internal derangement, such as disk repositioning and repair, diskectomy with and without grafts, articular surface contouring, high condylectomy, condylotomy, and arthroscopic surgery etc. Especially, it has been reported that the condylotomy produced the increase of the joint space, the pain relief, the elimination of the joint dysfunction due to the antero-inferiorly movement of the condyle, and the condylar morphologic change resulted from the progressive remodeling in TMJ without the surgical intervention within the TMJ. We have performed EVRO(extraoral vertical ramus osteotomy) to the 5 patients diagnosed as ADDWR(Anterior disk displacement with reduction) from June 1997 to December 1997 in the Chin-Hae military hospital. We diagnosed them with MRI and clinical examination. And we compared the preoperative symptoms with postoperative 2 months symptoms. They were compared by Helkimo index, mandibular mobility index, and pain scale. Anamnestic Index(Ai) was changed from 2.0 preoperatively to 1.2 postoperatively, clinical dysfunction score from 11.8 to 2.8, and Clinical Dysfunction Index(Di) from 2.8 to 1.2. The pain scale of the affected side was changed from 4.4 to 2.6 and that of the non-affeted side from 2.2 to 2.6. The maximal mouth opening was changed from 35.2mm to 40.9mm, right lateral excursion from 7.8mm to 8.0mm, left from 8.8mm to 7.0mm, and protrusion from 6.2mm to 6.2mm. In these results, we could not expect any excellent improvement of the clinical symptoms during the immediate postoperative periods. But we could observe the disappearance of the joint noise and the improvement of the clinical dysfunction score. On the basis of the results of the previous investigations about condylotomy effect which presented the condyle position were changed antero-inferiorly in the articular fossa during the immediate postoperative period, the displaced condyles may prevent wide mouth opening. Therefore it is elucidated that the improvement of the maximal mouth opening and other functions were restricted during the immediate postoperative periods. After long term follow-up period, the symptomatic and functional improvement will be expected by the passive repositioning of the proximal segment. We report the preliminary results with the related references.
Arthroscopy
;
Diskectomy
;
Follow-Up Studies
;
Hospitals, Military
;
Humans
;
Joints
;
Magnetic Resonance Imaging
;
Mouth
;
Noise
;
Postoperative Period
;
Temporomandibular Joint*
;
Transplants
8.Classification and Prognostic Significance of Immunophenotypic Subgroups in Non-T-ALL(I).
Seong Soo JANG ; Think You KIM
Korean Journal of Clinical Pathology 1998;18(2):234-239
BACKGROUND: Recently, the importance of immunologic subclassification based on surface marker expression of acute lymphoblastic leukemia (ALL) has been emphasized. The importance of immunophenotypic analysis of ALL has been documented by numerous studies, but study for survival rate of subgroups in the non-T-ALL was rarely documented in Korea. The aim of this study was to classify the non-T-ALL immunologically, and to compare the survival rates among the subgroups. MATERIALS AND METHODS: From April, 1987 to October, 1997, 142 patients diagnosed as non-T- ALL by immunophenotyping were classified into 6 subgroups, group I to group VI. Review of medical records were undertaken in 130 patients and analysed for survival rates. For the cases in whom CD20 not tested, classification was also undertaken into 4 groups. The survival analysis of immunophenotypic subgroups was carried out by Kaplan-Meier method and differences in survival rates were tested by the log-rank test. RESULTS: The 142 patients, which included patients in whom CD20 was not tested, were assigned into 4 groups as follows: Group I (2 cases, 1%), Group II (24 cases, 17%), Group III-V (110 cases, 78%), Group VI (6 cases, 4%). On the other hand, 113 patients in whom CD20 was tested, were assigned into 6 groups as follows: Group I (0 cases, 0%), Group II (22 cases, 20%), Group III (59 cases, 52%), Group IV (23 cases, 21%), Group V (3 cases, 3%), Group VI (5 cases, 4%). The result showed that median survival time was higher in Group III and Group III-V, and lower in Group VI. However, statistic difference was not seen for 6 subgroups, while in the study for 4 subgroups, statistic difference was seen (p=0.04). And in children, study for 6 subgroups and 4 subgroups showed statistic differences in survival rate. CONCLUSIONS: We conclude that immunophenotypic subclassification of Non-T-ALL is a valuable prognostic marker in children.
Child
;
Classification*
;
Hand
;
Humans
;
Immunophenotyping
;
Korea
;
Medical Records
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Prognosis
;
Survival Rate
10.Immunopathogenesis of Allergic Asthma: More Than the Th2 Hypothesis.
You Me KIM ; You Sun KIM ; Seong Gyu JEON ; Yoon Keun KIM
Allergy, Asthma & Immunology Research 2013;5(4):189-196
Asthma is a chronic obstructive airway disease that involves inflammation of the respiratory tract. Biological contaminants in indoor air can induce innate and adaptive immune responses and inflammation, resulting in asthma pathology. Epidemiologic surveys indicate that the prevalence of asthma is higher in developed countries than in developing countries. The prevalence of asthma in Korea has increased during the last several decades. This increase may be related to changes in housing styles, which result in increased levels of indoor biological contaminants, such as house dust mite-derived allergens and bacterial products such as endotoxin. Different types of inflammation are observed in those suffering from mild-to-moderate asthma compared to those experiencing severe asthma, involving markedly different patterns of inflammatory cells and mediators. As described in this review, these inflammatory profiles are largely determined by the involvement of different T helper cell subsets, which orchestrate the recruitment and activation of inflammatory cells. It is becoming clear that T helper cells other than Th2 cells are involved in the pathogenesis of asthma; specifically, both Th1 and Th17 cells are crucial for the development of neutrophilic inflammation in the airways, which is related to corticosteroid resistance. Development of therapeutics that suppress these immune and inflammatory cells may provide useful asthma treatments in the future.
Allergens
;
Asthma
;
Developed Countries
;
Developing Countries
;
Dust
;
Housing
;
Inflammation
;
Korea
;
Neutrophils
;
Prevalence
;
Pulmonary Disease, Chronic Obstructive
;
Respiratory System
;
Stress, Psychological
;
T-Lymphocytes, Helper-Inducer
;
Th17 Cells
;
Th2 Cells