1.Comparative study of radiologic-pathologic findings of experimental clonorchiasis in rabbits.
Kyung Nam RYU ; Jae Hoon LIM ; You Jung CHO ; Moon Ho YANG
Journal of the Korean Radiological Society 1993;29(1):1-8
Radiological investigation in patients with clonorchiasis is very important as this is the only method of evaluating the severity of clonorchiasis. In order to correlate the radiologic and pathologic findings of clonorchiasis, fourteen rabbits infested with Clonorchis sinensis and five control rabbits were examined radiologically by ultrasonography, computed tomography and cholangiography and the results were correlated with pathologic findings. Dilatation of the intrahepatic small bile ducts of the liver was due to obstruction by flukes: oval or elliptical small filling defects or irregular margin of the bile ducts on cholangiogram or intraluminal echoes on sonogram represented flukes per se; periductal thickening on sonogram and periductal enhancement of bile ducts on CT were due to inflammatory cell infiltration, adenomatous hyperplasia and periductal fibrosis: band like enhancement at the periphery of the liver on CT represented proliferated bile ducts, destruction of liver cells and resultant fibrosis. The study confirmed the pathological bases for the radiological findings of clonorchiasis in liver and bile ducts and will, perhaps, serve as a basis for the future radiologic-pathological correlation of clonorchiasis and in further clinical and experimental researches in the biliary tract diseases.
Bile Ducts
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Biliary Tract Diseases
;
Cholangiography
;
Clonorchiasis*
;
Clonorchis sinensis
;
Dilatation
;
Fibrosis
;
Humans
;
Hyperplasia
;
Liver
;
Methods
;
Rabbits*
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Trematoda
;
Ultrasonography
2.Solid pseudopapillary tumor with hepatic metastasis.
Woo Seok NAM ; Yong Sung WON ; Dong Do YOU ; Jin Mo YANG ; Jee Han JUNG
Journal of the Korean Surgical Society 2011;81(Suppl 1):S55-S58
Solid pseudopapillary tumor of the pancreas is a rare tumor that affects young females with low malignant potential and good prognosis with more than 90% survival at 5 years. Metastasis is very rare. We report the case of a 74-year-old female who had pancreatic solid-pseudopapillary tumor and synchronous hepatic metastasis.
Aged
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Female
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Humans
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Neoplasm Metastasis
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Pancreas
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Pancreatic Neoplasms
;
Prognosis
4.A Case of Exercise-Induced Anaphylaxis Presenting with Lower Lid Angioedema.
Jung Ran YOU ; Min Hee KIM ; Youn Mi SUNG ; Suk Woo YANG
Journal of the Korean Ophthalmological Society 2015;56(9):1459-1463
PURPOSE: To describe a case of exercise-induced anaphylaxis presenting with lower lid angioedema. CASE SUMMARY: A 35-year-old female patient for the past 3 years experienced lower lid edema in her left eye after exercising. In the treadmill exercise test, sneezing, coughing, and lower lid edema in her left eye appeared 13 minutes after initiating exercise. Additionally, contrast-enhanced computed tomography scan revealed minimal soft tissue thickening of the left inferior periorbital subcutaneous area with subtle enhancement after exercise. The serum immunoglobulin E (IgE) test showed elevated total IgE levels. The patient was diagnosed with exercise-induced anaphylaxis based on the above results. We informed the patient on her trigger factors and possible symptoms and prescribed an oral antihistamine and steroid. CONCLUSIONS: In patients presenting with facial edema or eyelid edema after exercise, the possibility of exercise-induced anaphylaxis should be considered. In addition, we have to aware of possibility of complication such as airway obstruction or a life-threatening condition, and it is needed to prevent a recurrence of anaphylaxis by cooperating with other department.
Adult
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Airway Obstruction
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Anaphylaxis*
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Angioedema*
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Cough
;
Edema
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Exercise Test
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Eyelids
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Female
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Humans
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Immunoglobulin E
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Immunoglobulins
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Recurrence
;
Sneezing
5.A comparative study of the puberty suppression effect of gonadotropin-releasing hormone agonist in precocious or early puberty girls.
Kye Shik SHIM ; Chong Woo BAE ; You Jung YANG
Korean Journal of Pediatrics 2008;51(6):634-639
PURPOSE: There has been considerable disagreement regarding the most appropriate dosage of gonadotropin-releasing hormone agonist in cases of central precocious puberty. The aim of this study was to determine the appropriate dosage for suppression of the puberty in girls with central precocious or early puberty. METHODS: Twenty-two girls with early puberty were randomly subjected to 3 types of dosages of leuprolide acetate for at least 6 months. The number of cases in groups 1, 2, and 3 were 7, 7, and 8, and dosages were 70, 90, and 110 microgram/ kg/-month, respectively. Height, weight, bone age, Tanner stage of breast development, and serum levels of LH, FSH, estradiol, and progesterone were measured before treatment and after 6 months of treatment. The number of cases of puberty suppression was compared using a modified puberty suppression score with a nonparametric chi-square test. RESULTS: There were no significant differences of chronologic and bone ages among the groups. There was a significant decrease in height SDS gain after 6 months in group 3 (P<0.05) compared with groups 1 and 2. Serum levels of LH, FSH, estradiol and progesterone were all significantly decreased after treatment in all 3 groups (P<0.05). The number of cases of puberty suppression in each group were 4 (57%), 5 (71%), and 8 (100%). There was a significantly increased proportion of suppression of puberty in group 3 (P<0.05). CONCLUSION: It was necessary to use a higher dose of gonadotropin-releasing hormone agonist to suppress early puberty in girls; however further longitudinal study will be needed for their prognosis of final adult height.
Adult
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Breast
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Estradiol
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Gonadotropin-Releasing Hormone
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Humans
;
Leuprolide
;
Longitudinal Studies
;
Progesterone
;
Prognosis
;
Puberty
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Puberty, Precocious
6.Amniotic fluid index changes in normal pregnancy.
Chan Young JUNG ; Sung Yong LEE ; You Gon KIM ; Pong Rim JANG ; Woo Young LEE ; Yang Seo PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1509-1513
No abstract available.
Amniotic Fluid*
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Female
;
Pregnancy*
7.A Case of White Fibrous Papulosis of the Neck.
Jung Hoon YANG ; Jung Woong SHIN ; Sung Yul LEE ; Moon Kyun CHO ; You In BAE ; Sanghoon LEE
Korean Journal of Dermatology 2010;48(9):817-819
White fibrous papulosis of the neck is a rare skin disease that manifests with tiny papules that are distributed on the neck. Thick collagen bundles in the papillary dermis and diminution of the elastic fiber are characteristic on histologic examination. It is thought to be a normal aging process of the skin or an associated disorder. We report here on a case of white fibrous papulosis of the neck of a 49-year-old Korean woman.
Aging
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Collagen
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Dermis
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Elastic Tissue
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Female
;
Humans
;
Middle Aged
;
Neck
;
Skin
;
Skin Diseases
8.Unusual case report as imported sparganosis.
Kyung Sik KO ; Hyung Keun CHUNG ; Myung Jae PARK ; Hwan Jo SUH ; Jung Youl CHUN ; Kyung Nam RYU ; Hyun Jong YANG ; You Jung CHO ; Yung Han PAIK
Korean Journal of Infectious Diseases 1992;24(1):65-69
No abstract available.
Sparganosis*
9.The Effect of Traumatic Experiences in Childhood on Depressive Symptoms for College Students : Focusing on the Moderating Effects of Positive Psychological Resources
Young Eun JUNG ; Hyun Ju YANG ; Jung Won YOU ; Moon Doo KIM
Mood and Emotion 2018;16(3):163-168
OBJECTIVES: The purpose of this study was to examine effects of traumatic experiences in childhood, on depressive symptoms of college students, and to determine how depression depended on positive psychological resources.METHODS: A total of 430 students were recruited, from two universities in Jeju area. All participants completed self-report questionnaires, that included demographic variables, Adverse Childhood Experience (ACE) Scale, Patient Health Questionnaire-9, and Positive Resources Test (POREST).RESULTS: Prevalence of depression was 47.9%, and a total of 133 (30.9%) college students reported traumatic experiences in childhood. Students with depressive symptoms, were likely to report more traumatic experiences in childhood, and less positive psychological resources. Results from regression analyses indicated that, while controlling for a range of demographic variables, positive psychological resources moderated the association, between traumatic experiences in childhood and depression.CONCLUSION: Based on results, professionals must consider positive psychological and social resources, for treatment to reduce depressive symptoms in patients with history of childhood adversity.
Depression
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Humans
;
Prevalence
10.Use of positron emission tomography-computed tomography to predict axillary metastasis in patients with triple-negative breast cancer
Jung Hyun YOUM ; Yoona CHUNG ; You Jung YANG ; Sang Ah HAN ; Jeong Yoon SONG
Korean Journal of Clinical Oncology 2018;14(2):135-141
PURPOSE: Axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) are important for staging of patients with node-positive breast cancer. However, these can be avoided in select micrometastatic diseases, preventing postoperative complications. The present study evaluated the ability of axillary lymph node maximum standardized uptake value (SUVmax) on positron emission tomography-computed tomography (PET-CT) to predict axillary metastasis of breast cancer.METHODS: The records of invasive breast cancer patients who underwent pretreatment (surgery and/or chemotherapy) PET-CT between January 2006 and December 2014 were reviewed. ALNs were preoperatively evaluated by PET-CT. Lymph nodes were dissected by SLNB or ALND. SUVmax was measured in both the axillary lymph node and primary tumor. Student t-test and chi-square test were used to analyze sensitivity and specificity. Receiver operating characteristic (ROC) and area under the ROC curve (AUC) analyses were performed.RESULTS: SUV-tumor (SUV-T) and SUV-lymph node (SUV-LN) were significantly higher in the triple-negative breast cancer (TNBC) group than in other groups (SUV-T: 5.99, P < 0.01; SUV-LN: 1.29, P=0.014). The sensitivity (0.881) and accuracy (0.804) for initial ALN staging were higher in fine needle aspiration+PET-CT than in other methods. For PET-CT alone, the subtype with the highest sensitivity (0.870) and negative predictive value (0.917) was TNBC. The AUC for SUV-LN was greatest in TNBC (0.797).CONCLUSION: The characteristics of SUV-T and SUV-LN differed according to immunohistochemistry subtype. Compared to other subtypes, the true positivity of axillary metastasis on PET-CT was highest in TNBC. These findings could help tailor management for therapeutic and diagnostic purposes.
Area Under Curve
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Breast Neoplasms
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Electrons
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Humans
;
Immunohistochemistry
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Lymph Node Excision
;
Lymph Nodes
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Lymphatic Metastasis
;
Needles
;
Neoplasm Metastasis
;
Postoperative Complications
;
ROC Curve
;
Sensitivity and Specificity
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Sentinel Lymph Node Biopsy
;
Triple Negative Breast Neoplasms