The previous reports about Supracondylar-Condylar Fracture of the femur which extends to articular surfaces revealed poor results in general, regardless of the methods of treatment. But those results are thought to be much alleviated if they are treated according to the principles of ASIF. Fifteen cases of Supracondylar-condylar fractures of the femur from 13 patients were treated by open reduction and rigid internal fixation during last 3 years at Department of Orthopedic Surgery, Early mobilization of knee joint was permissible in most of the cases without loss of fixation or other complications during convalescence Subsequently, greatifying results were obtained as observed in varying period of follow up days.
Convalescence ; Early Ambulation ; Femur ; Follow-Up Studies ; Humans ; Knee Joint ; Orthopedics

BACKGROUND: Chronic pain is often associated with changes in the immune responses, which highlights the need for the aggressive pain control to obtain a better prognosis. This study examined splenic NK cell cytotoxicity in an attempt to assess the possible changes in the immune function under chronic neuropathic pain after a partial transsection of the sciatic nerve. METHODS: After confirming tactile allodynia in response to the von Frey filament, a modified lactate dehydrogenase (LDH) release assay was used to determine the cytotoxic activity of splenic NK cells on the YAC-1 cell line in C3H/HeN (H-2k) mice (n = 6). NK cells as effector cells were mixed with YAC-1 cells as target cells (1 x 10(4)/100microliter), resulting in an effector-target ratio of 1 : 25, 1 : 50, 1 : 100 in the culture medium. RESULTS: At 1 and 2 weeks after the nerve injury, all the subjects showed significant mechanical sensitivity compared with those observed before surgery. The percentage of NK cell cytotoxicity of the neuropathic mice increased significantly 1 week after the nerve injury but decreased within 2 weeks compared with the normal mice. CONCLUSIONS: In terms of the altered NK cell cytotoxicity, neuropathic pain can cause changes in the normal performance of the immune function.
Animals ; Cell Line ; Chronic Pain ; Cytotoxicity Tests, Immunologic ; Hyperalgesia ; Immune System ; Killer Cells, Natural* ; L-Lactate Dehydrogenase ; Mice* ; Neuralgia ; Peripheral Nerve Injuries* ; Peripheral Nerves* ; Prognosis ; Sciatic Nerve

Healing of periodontal tissues require the migration and proliferation of gingival fibroblasts and periodontal ligament cells. There is many evidences that the some agents like cytokines and polypeptide growth factors are mediate these cellular events in wound healing. Recently someone is interested in herbal drugs on periodontal tissue healing processes. The purpose of this study was to examine the effects of 4 herbal drugs, Carthami Flis, Moutan Radicis Cortex, Scirpi Rhisoma, Seed of Carthamus tinctorius L. on human gingival fibroblasts and periodontal ligament cells. Periodontal ligament cells and gingival fibroblasts were primarily cultured from extracted premolar with non-periodontal diseases. The powder from extracted herbal drugs were prepared with distilled water. Cells were cultured with DMEM at 37degrees C, 5% CO2, 100% humidity incubator, and treated with each herbal drugs with proper concentration for 1, 2, and 3 days. The cell activity was determined by ELISA reader using MTT assay. There was the most significant elevation in 10(-3)g/ml of almost herbal drugs on cellular activities. The result of this study demonstrated that Carthami Flis, Moutan Radicis Cortex, Scirpi Rhisoma, Seed of Carthamus tinctorius L. appears to have beneficial effect on healing process after periodontal treatment.
Bicuspid ; Carthamus tinctorius ; Cytokines ; Enzyme-Linked Immunosorbent Assay ; Fibroblasts* ; Humans ; Humidity ; Incubators ; Intercellular Signaling Peptides and Proteins ; Periodontal Ligament* ; Water ; Wound Healing

Bowen's disease is an intraepidermal squamous cell carcinoma. Although an invasive squamous cell carcinoma occasionally develops from Bowen's disease, the development of sebaceous carcinoma from Bowen's disease is very rare. We report a case of sebaceous carcinoma arising from Bowen's disease occurring on the cheek in a 72-year-old female. She presented with a crust and erythematous scaly papule on the face. Histopathologic examination of the crusted lesion showed atypical tumor cells with large, hyperchromatic nuclei and frequent mitoses in the epidermis suggesting of Bowen's disease. However, the scaly papule showed tumor lobule composed of clear cells with foamy cytoplasm and atypical undifferentiated cells suggesting of sebaceous carcinoma. CK7 staining was positive only for the tumors cells of the specimen from the scaly papule. The positive staining of CK7 may help distinguish sebaceous carcinoma from clear cell squamous cell carcinoma when that distinction can not be clearly made by light microscopy alone.
Aged ; Bowen's Disease* ; Carcinoma, Squamous Cell ; Cheek ; Cytoplasm ; Epidermis ; Female ; Humans ; Microscopy ; Mitosis

No abstract available.
Axons ; Hand ; Humans

Foreign body aspiration is most likely to occur in children and in adults aged above 60 years, causing a respiratory emergency, such as airway closure. It is diagnosed based on a history of aspiration, presenting symptoms, and radiographic findings. The treatment may include removal of the foreign body via bronchoscopy or surgery. Here, we report a rare case of bronchial aspiration of a foreign body, confirmed with clinical and radiographic examinations, in a 57-year-old patient. The patient was transferred for treatment; however, spontaneous passage of the foreign body to the gastrointestinal tract led to its removal from the bronchus.
Adult ; Bronchi ; Bronchoscopy ; Child ; Emergencies ; Foreign Bodies ; Gastrointestinal Tract ; Humans ; Middle Aged ; Respiratory Aspiration

Kikuchi-Fujimoto disease (KFD) is a benign self-limiting disease characterized by fever and lymphadenitis. The etiology and pathogenesis of KFD is unclear. However, two hypotheses have been suggested: a viral infection hypothesis and an autoimmune hypothesis. Several KFD patients with various types of autoimmune diseases have been reported, and these reports support the hypothesis for autoimmune pathogenesis of KFD. Here, we report the case of a 17-year-old female patient diagnosed with KFD and autoimmune thyroiditis. This case serves as additional evidence that the etiology of KFD is autoimmune origin.
Adolescent ; Autoimmune Diseases ; Female ; Fever ; Histiocytic Necrotizing Lymphadenitis ; Humans ; Lymphadenitis ; Thyroiditis, Autoimmune

Anti-Ma2-associated encephalitis is one of the paraneoplastic neurological syndromes. It has been shown to be associated with various neoplasms, mainly testicular, lung, and breast cancers. Most patients with anti-Ma2-associated encephalitis present limbic-diencephalic-brainstem dysfunctions such as seizure, mood disorder, excessive daytime sleepiness, and ophthalmoparesis. Some patients develop symptoms indicating the multifocal involvement of the limbic system, diencephalon, or brainstem. However, there are few case studies of anti-Ma2-associated encephalitis presenting as isolated hypersomnia. We report a case of anti-Ma2-associated encephalitis presenting as hypersomnia.
Brain Stem ; Breast ; Diencephalon ; Disorders of Excessive Somnolence* ; Encephalitis* ; Humans ; Limbic System ; Lung ; Mood Disorders ; Ophthalmoplegia ; Paraneoplastic Syndromes ; Seizures

No abstract available.
Humans* ; Pregnancy* ; Sperm Injections, Intracytoplasmic* ; Spermatozoa*

Bupivacaine is frequently used for pain control and local anesthesia. However, it is associated with certain acute and fatal side effects, although rare, including cardiac and central nervous system toxicities. In particular, bupivacaine-induced cardiac toxicity may be fatal. This condition can be diagnosed as bupivacaine-induced cardiotoxicity by excluding other causes and determining a history of bupivacaine administration. However, in emergency situations, recognizing bupivacaine toxicity can be difficult due to the physician's lack of awareness regarding the condition or in the absence of clear communication regarding the patient's medical history. In the current case report, we describe our experience with strong suspected bupivacaine-induced cardiotoxicity in a patient who underwent cesarean section along with a review of the literature.
Anesthesia, Local ; Bupivacaine* ; Cardiomyopathies* ; Cardiotoxicity ; Central Nervous System ; Cesarean Section* ; Emergencies ; Female ; Humans ; Peripartum Period* ; Pregnancy