1.Hypomelia-Hypotrichosis-Facial Hemangioma Syndrome.
Wook LEW ; Dong Kun KIM ; Nam Joon CHO ; You Chan KIM ; Hui Wan PARK
Annals of Dermatology 1995;7(4):358-360
We report a mild variant of hypomelia-hypotrichosis-facial hemangioma syndrome in a 3 month-old female. The patient showed major features of the previously reported cases including flexion deformities of both upper extremities, sparse light colored hair, mid-facial hemangioma and a characteristic facial appearance. Roentgenogram showed radio-humeral synostosis at both elbow joints by which shortening of upper limbs could be anticipated. However, intra- and extrauterine growth retardation were not remarkable and the lower limbs were not affected.
Congenital Abnormalities
;
Elbow Joint
;
Female
;
Hair
;
Hemangioma*
;
Humans
;
Hypotrichosis
;
Lower Extremity
;
Synostosis
;
Upper Extremity
2.Clinical analysis of bladder dysfunction after vaginal delivery.
Jin Shouk HUH ; Yong CHO ; Sung Won LEE ; You Dong CHO ; Eu Sun RO ; Yong Pil KIM ; Sun Uk KWON
Korean Journal of Obstetrics and Gynecology 1993;36(7):1496-1501
No abstract available.
Urinary Bladder*
3.A clinical analysis of ectopic pregnancy.
You Dong CHO ; Byung Tae MOON ; Yong CHO ; Eui Sun RO ; Yong Pill KIM ; Soon Uck KWON
Korean Journal of Obstetrics and Gynecology 1993;36(7):2863-2871
No abstract available.
Female
;
Pregnancy
;
Pregnancy, Ectopic*
4.A Case of Acute Tubular Necrosis Induced by Paraquat (Gramoxon) Intoxication.
Young Guk KIM ; Dong Gun PARK ; Kee Hwan YOU ; Keun Heang CHO ; Young Sook HONG ; Soon Kyum KIM
Journal of the Korean Pediatric Society 1994;37(8):1143-1148
Paraquat (1, 1'-dimethy-14, 4' dipyridium chloride: Gramoxon(r)) was first discovered in England in 1955. It has been widely distributed for use in Korea since 1970 as a pesticide and also often the cause of accidental intoxications. The authors would like to report the following case of paraquat intoxicatio in a 13 year old female child admitted via emergency room with complaints of epigastric pain, vomiting and hematuria of four days duration. On admission the data of laboratory evaluation were as follows: BUN/Cr 126/11.6 mg/dl; sGOT/sGPT 641/641 IU/L; total bilirubin/direct bilirubin 3.9/2.4 mg/dl; alkaline phosphatase 396.1 U/L; fecal occult blood test-positive; pH 7.428, pCO2 26.2 mmHg, pO2 131.4 mmHg, base excess -5.0 mmol/L on arterial blood gas analysis (ABGA). Gastroendoscopy revealed esophageal ulcers, and as symptoms of renal failure could not be relieved by hemodialysis, kidney biopsy was performed on the otherwise previously healthy child to establish the cause of renal failure. The result of biopsy revealed tubular necrosis with eosinophilic infiltrations. A more detailed retrograde probe of the child's past medical history evoked that the patient had ingested paraquat in a suicidal attempt. Supportive therapy and hemodialysis were continued thereafter, but the symptoms of renal failure could not be reversed, and the patient eventually died due to acute respiratory distress syndrome.
Adolescent
;
Alkaline Phosphatase
;
Bilirubin
;
Biopsy
;
Blood Gas Analysis
;
Child
;
Emergency Service, Hospital
;
England
;
Eosinophils
;
Female
;
Hematuria
;
Humans
;
Hydrogen-Ion Concentration
;
Kidney
;
Korea
;
Necrosis*
;
Occult Blood
;
Paraquat*
;
Renal Dialysis
;
Renal Insufficiency
;
Respiratory Distress Syndrome, Adult
;
Ulcer
;
Vomiting
5.In vitro Effect of Kalopanaxsaponin A on the Ultrastructure of Trichomonas vaginalis.
Dong Jin KIM ; You Jung CHO ; Jong Phil CHU
Infection and Chemotherapy 2003;35(6):446-453
BACKGROUND: T. vaginalis is a pathogenic protozoa infecting genitourinary tract. Metronidazole is a drug of choice to treat T. vaginalis infection. However, because of appearance of metronidazole- resistant T. vaginalis, it is needed to develop an alternative drug. So, we evaluated the effects of various concentration of kalopanaxsaponin A against T. vaginalis. METHODS: The antiprotozoal effect of kalopanaxsaponin A on the growth and fine structure of T. vaginalis was examined by using trypan blue exclusion assay and electron microscopy. RESULTS: The viability test showed markedly decreased number of T. vaginalis, treated with increasing concentration of kalopanaxsaponin A. We evaluated the electron microscopic findings for antiprotozoan effects against T. vaginalis. SEM showed that in T. vaginalis treated with 4 microgram/mL for 1 hour, axostyle was shrinked and flagella began to disappear. With gradual increase of the concentration of kalopanaxsaponin A, destruction of cell membrane was getting more severe, and degenerative change was observed in T. vaginalis treated with 8 microgram/mL for 2 hours. TEM showed that in T. vaginalis treated with 4 microgram/mL for 2 hours, the vacuoles in cytoplasm were larger and hydrogenosomes were smaller than those in control group. The number of vacuole was increased, the nucleus was destroyed, the number of polyribosome and free ribosome was also decreased in trichomonads treated with kalopanaxsaponin A (8 microgram/mL), which indicated the occurrence of degenerative changes. CONCLUSION: These results indicated that kalopanaxsaponin A had the antiprotozoal effect on T. vaginalis by inhibition of cell multiplication as well as an impairment of protein synthesis.
Cell Membrane
;
Cell Proliferation
;
Cytoplasm
;
Flagella
;
Metronidazole
;
Microscopy, Electron
;
Polyribosomes
;
Ribosomes
;
Trichomonas vaginalis*
;
Trichomonas*
;
Trypan Blue
;
Vacuoles
6.In vitro Effect of Kalopanaxsaponin A on the Ultrastructure of Trichomonas vaginalis.
Dong Jin KIM ; You Jung CHO ; Jong Phil CHU
Infection and Chemotherapy 2003;35(6):446-453
BACKGROUND: T. vaginalis is a pathogenic protozoa infecting genitourinary tract. Metronidazole is a drug of choice to treat T. vaginalis infection. However, because of appearance of metronidazole- resistant T. vaginalis, it is needed to develop an alternative drug. So, we evaluated the effects of various concentration of kalopanaxsaponin A against T. vaginalis. METHODS: The antiprotozoal effect of kalopanaxsaponin A on the growth and fine structure of T. vaginalis was examined by using trypan blue exclusion assay and electron microscopy. RESULTS: The viability test showed markedly decreased number of T. vaginalis, treated with increasing concentration of kalopanaxsaponin A. We evaluated the electron microscopic findings for antiprotozoan effects against T. vaginalis. SEM showed that in T. vaginalis treated with 4 microgram/mL for 1 hour, axostyle was shrinked and flagella began to disappear. With gradual increase of the concentration of kalopanaxsaponin A, destruction of cell membrane was getting more severe, and degenerative change was observed in T. vaginalis treated with 8 microgram/mL for 2 hours. TEM showed that in T. vaginalis treated with 4 microgram/mL for 2 hours, the vacuoles in cytoplasm were larger and hydrogenosomes were smaller than those in control group. The number of vacuole was increased, the nucleus was destroyed, the number of polyribosome and free ribosome was also decreased in trichomonads treated with kalopanaxsaponin A (8 microgram/mL), which indicated the occurrence of degenerative changes. CONCLUSION: These results indicated that kalopanaxsaponin A had the antiprotozoal effect on T. vaginalis by inhibition of cell multiplication as well as an impairment of protein synthesis.
Cell Membrane
;
Cell Proliferation
;
Cytoplasm
;
Flagella
;
Metronidazole
;
Microscopy, Electron
;
Polyribosomes
;
Ribosomes
;
Trichomonas vaginalis*
;
Trichomonas*
;
Trypan Blue
;
Vacuoles
7.A pathogenetic role of T-lymphocytes in the development of IgE-mediated respiratory allergy : analysis of T-lymphocytes by flowcytometry and lymphocyte blastogenesis to allergens and mitogens.
You Young KIM ; Sang Heon CHO ; Dong Chull CHOI ; Ho Joo YOON ; Kyung Up MIN ; Young Joo CHO ; Hee Bum MON
Korean Journal of Medicine 1993;45(6):703-712
No abstract available.
Allergens*
;
Hypersensitivity*
;
Lymphocyte Activation*
;
Lymphocytes*
;
Mitogens*
;
T-Lymphocytes*
8.Clinical investigation of patients with acute paraquat poisoning and a case report of patient who survived repeated intoxication.
Myoung Chai KWAK ; You Hyun CHO ; Pil Kyu KANG ; Hong Hyou CHO ; Gi Young YI ; Dong Chan JIN ; Du Hyok CHOI
Journal of the Korean Academy of Family Medicine 1992;13(2):173-180
No abstract available.
Humans
;
Paraquat*
;
Poisoning*
9.Effect of Posterior Urethral Reconstruction (PUR) in Early Recovery of Urinary Continence after Robotic-Assisted Radical Prostatectomy.
Soo Dong KIM ; Tae Hyo KIM ; Jae Wook CHO ; Youn Chul YOU ; Gyung Tak SUNG
Korean Journal of Urology 2009;50(12):1203-1207
PURPOSE: Prolonged urinary incontinence is one of the greatest concerns for patients undergoing radical prostatectomy. One of the possible causes for this urinary incontinence is a postoperative deficiency of the external striated urethral sphincter (EUS) complex and continence nerves. We evaluated the effect of posterior urethral reconstruction (PUR) in the early recovery of urinary continence after robotic-assisted radical prostatectomy. MATERIALS AND METHODS: Between January 2008 and March 2009 we performed robotic-assisted radical prostatectomy with PUR in 30 patients (PUR group) and without PUR in 30 patients (non-PUR group). We compared perioperative parameters and postoperative continence rates between the two groups. Continence was defined as no pads or one diaper per 24 hours and was assessed 1 month, 3 months, and 6 months after the procedure. RESULTS: Patients in the PUR group achieved better continence rates at 1 month (43% vs. 35%) and 3 months of follow-up (89% vs. 64%). At 6 months of follow-up, the continence rate was similar between the two groups (96% vs. 90%). No major complications were observed in the PUR group. However, 2 cases of anastomotic site leakage and 1 case of delayed bleeding were observed in the non-PUR group. CONCLUSIONS: Posterior urethral reconstruction appears to be an easy and reproducible technique in robotic-assisted radical prostatectomy. Our early experience demonstrates that PUR in robotic-assisted radical prostatectomy appears to confer early continence recovery and reduce intraoperative complications.
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Intraoperative Complications
;
Prostatectomy
;
Robotics
;
Urethra
;
Urinary Incontinence
10.Posterior C2-C3 Fixation for Unstable Hangman's Fracture.
Dong Hwan JEONG ; Nam Kyu YOU ; Chul Kyu LEE ; Ki Hong CHO ; Sang Hyun KIM
Korean Journal of Spine 2013;10(3):165-169
OBJECTIVE: This is a retrospective review of 13 unstable Hangman's fractures who underwent posterior C2-3 fixation to describe clinical outcomes with a literature review. METHODS: Thirteen patients for unstable Hangman's fracture were enrolled between July 2007 and June 2010 were included in this study. The medical records of all patients were reviewed. Concurrently, clinical outcomes were evaluated using Neck Disability Index (NDI) scores and Visual Analogue Scale (VAS) scores during preoperative and postoperative follow up period. Plain radiographs were obtained on postoperative 1day, 1week, and then at 1, 2, 6, and 12 months. CT was done at postoperative 12 months in all patients for evaluation of bone fusion. The mean period of clinical follow-up was 17 months. RESULTS: Mean age were 43 years old. Bone fusion was recognized in all cases at the final follow-up. The average preoperative VAS score for neck pain was 8.3+/-1.1, while the final follow-up VAS score was 2.07+/-0.8 (p<0.001). The average immediate postoperative NDI was 84% points and final NDI was 22% points (p<0.001). There were one case of infection and 1 case of screw loosening. CONCLUSION: In the treatment of the patients with unstable Hangman's fracture, posterior C2-C3 fusions is effective and curative treatments to achieve cervical spinal stability.
Follow-Up Studies
;
Humans
;
Medical Records
;
Neck
;
Neck Pain
;
Retrospective Studies