2.Clinical study on cancers in the bile duct, the pancreas head region and the liver and liver cirrhosis.
Noboru SASAKI ; Kunisuke INOUE ; Masaharu KAWAGUCHI ; Hiroshi MUTO ; Shunji HIRATA ; Satoru MORITA ; Yoshitaka SEKIGUCHI ; Seiryo TAKASHINA
Journal of the Japanese Association of Rural Medicine 1986;35(4):772-778
We evaluated the therapeutic results of cancers in the bile duct, the pancreas head region and the liver and cirrhosis.
The former two types were examined in a total of 49 cases: 10 cholecystocarcinomas, 18 cholangiocarcinomas, 6 papillocarcinomas, and 15 pancreas head cancers. Radical surgery was performed in only 9 cases: 1 cholecystocarcinoma, 1 cholangiocarcinoma, 5 papillocarcinomas and 2 pancreas head cancers. The surgical success rate was satisfactory 83%(5/6) for papillocarcinoma, yet showed 18.4% overall.
Liver cancer and cirrhosis were examined in 102 cases: 78 cirrhoses and 24 livercancers. Of the former, 15% were viral cirrhosis, 44% alcoholic, 1% specific and 40% unknown. Ofthe latter, 29% were viral liver cancer, 29% alcoholic and 42% unknown.
Treatment of these cancers, with the exception of one type, was unfavorable. To increase the surgical success rate, cancers will have to be discovered earlier using such recent, highly-advanced technological means as endoscopy, ultrasonography, angiography and computerized tomography. At the same time, radical surgery should be actively applied in a broader range of cases.
In cirrhosis, bleeding in the upper digestive tract and complicating liver cancer are increasing in frequency due to prolonged life expectancy. How to manage this increase remains subject for further study in the future.
3.Workload and health of farmers of middle age or over in the suburbs of a city of Hiroshima Prefecture with special reference to blood test findings.
Seiryo TAKASHINA ; Yoshitaka SEIKIGUCHI ; Toyofumi MITSUYAMA ; Hidetaka SENO ; Sachihiko GOMYO ; Kazuhiko HATTA ; Sachihiro YOKOTA ; Naoki MORITA ; Yasuyuki YOKOZAKI ; Masao DOI
Journal of the Japanese Association of Rural Medicine 1984;33(4):749-758
A questionnaire was conducted on the living and working conditions of inhabitants in the suburbs of a city in Hiroshima Prefecture. Respondents received medical and nutritional examinations. A summary of our findings is as follows:
Those persons who are apparently overworking themselves eke out their energy deficiency by taking diets rich in carbohydrate complex. Their major health problems are hypertension, ischemic changes in ECG, anemia and lower cholinesterase activity.
There were indications that agricultural chemicals have harmful effects on the health of the examinees.
In contrast, many of those who work less consume large-even excessive-amounts of animal proteins and fats. Among them prevail liver failxure and metabolic disorders.
In either group of the people examined, there was amundant evidence to show that they are at risk of developing arteriosclerosis.
These findings should be taken into consideration when a health control program is implemnted.
4.Efficacy of limited-duration spinal cord stimulation for subacute postherpetic neuralgia.
Masako ISEKI ; Yoshihito MORITA ; Yoshitaka NAKAMURA ; Masataka IFUKU ; Shuji KOMATSU
Annals of the Academy of Medicine, Singapore 2009;38(11):1004-1006
Excellent outcomes were achieved with spinal cord stimulation (SCS) for 7 to 10 days on 2 patients who developed postherpetic neuralgia. Both patients were within 2 to 3 months of the onset of the condition, and nerve blocks provided only temporary pain relief and drug therapies had poor efficacy. The authors believe that limited-duration SCS for subacute postherpetic neuralgia is a useful treatment approach that may prevent the pain from progressing to chronic postherpetic neuralgia.
Aged
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Electric Stimulation Therapy
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methods
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Female
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Herpes Zoster
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complications
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Humans
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Neuralgia, Postherpetic
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etiology
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physiopathology
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therapy
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Outcome Assessment (Health Care)
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Pain, Intractable
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therapy
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Spinal Cord
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physiology
5.Efficacy of the Envelope Method in Applying Polyglycolic Acid Sheets to Post-Endoscopic Submucosal Dissection Ulcers in Living Pigs
Hiroya SAKAGUCHI ; Toshitatsu TAKAO ; Yoshitaka TAKEGAWA ; Yuki KOGA ; Kazunori YAMANAKA ; Masataka SAGATA ; Shinwa TANAKA ; Yoshinori MORITA ; Takashi TOYONAGA ; Yuzo KODAMA
Clinical Endoscopy 2021;54(1):64-72
Background/Aims:
Application of polyglycolic acid (PGA) sheets using fibrin glue in post-endoscopic submucosal dissection (ESD) ulcers to prevent bleeding has been reported to be difficult with the conventional delivery method because of gravity. This study assessed the usefulness of the envelope-based delivery system with and against gravity in living pigs.
Methods:
PGA sheets were applied on post-ESD ulcers with and against gravity six times each using the conventional and envelope methods, respectively. The PGA sheet delivery time and the endoscopic and histological findings of the treated ulcer floors were compared.
Results:
With gravity, the median PGA sheet application time was 1.00 (0.68–1.30) min/cm2 and 0.32 (0.18–0.52) min/cm2 with the conventional and envelope techniques (p=0.002), respectively, and against gravity, it was 1.20 (1.13–1.63) min/cm2 and 0.50 (0.39–0.58) min/cm2 (p=0.002), respectively. Against gravity, the endoscopic and histological findings revealed that the conventional group had insufficient fixation of the PGA sheets, but the envelope groups had sufficient fixation. The results with gravity were similar between the groups.
Conclusions
The envelope method makes it possible to deliver PGA sheets to the stomach quickly and cover ulcers appropriately both with and against gravity in living pigs.