1.A Case of Complete Thrombotic Occlusion by Endovascular Stent Grafting for Anastomosis Leakage after Aortic Arch Replacement of Stanford Type A Dissecting Aortic Aneurysm.
Hiroaki Ichihashi ; Shin Ishimaru ; Taro Shimazaki ; Yoshihiko Yokoi ; Satoshi Kawaguchi ; Hiromi Yano ; Yukio Obitsu ; Mikio Ishikawa
Japanese Journal of Cardiovascular Surgery 1999;28(4):256-259
A 60-year-old woman with acute Stanford type A dissecting aneurysm underwent Dacron graft replacement of the total aortic arch combined with the modified elephant trunk technique. Follow-up CT and angiogram demonstrated blood flow into the false lumen from the distal anastomosis. In order to interrupt the blood flow, endovascular stent grafting was undertaken. She recovered uneventfully, and was discharged on the 14th postoperative day. Follow-up CT taken in the third postoperative month demonstrated exclusion of the blood flow into the false lumen of descending thoracic aorta. Aortic arch replacement followed by endovascular stent grafting of the descending thoracic component is a potential therapeutic option in patients with dissecting aneurysm.
2.The preliminary report of occult HBV infection in Vietnamese
Truong Xuan Bui ; Bang Van Nguyen ; Phuong Minh Tran ; Trach Khanh Nguyen ; Quy Tran ; Yoshihiko Yano ; Yasushi Seo ; Yoshitake Hayashi
Journal of Medical Research 2007;47(1):28-32
Background: Vietnam is located in the endemic region of hepatitis B virus (HBV) infection, but no data of occult HBV infection was reported at present. Objectives: To investigate the prevalence of occult HBV infection in different ethnics of people and generations. Subjects and method: 80 voluteers with HbsAg negative from five different ethnics: Kinh, Tay, Mong, Giay and Dao in a Chino \ufffd?Vietnamses border province (Lao Cai) were enrolled in the study. After HBV-DNA was extracted, nested PCR of S gene and of Core-promoter/Pre-core region were used to detect HBV-DNA. Specifying nucleotide sequence was confirmed by direct sequencing. Results:The prevalence of occult HBV infection in population study was very high 73/80 (91,3%) by nested PCR of Core-promoter/Pre-core, significantly more sensitive than nested PCR of S gene (26,3%) (p<0,0001). The prevalence of occult HBV infection was notdifferent between ethnics of people or between children, adults. Conclusion: Occult HBV infection in Vietnamese is very common; however, nationwide further studies should be carried out to confirm this preliminary results and evaluate the impact of occult HBV infection in Vietnam.
Hepatitis B virus
;
Hepatitis B Surface Antigens
;
3.Clinical characteristics and molecular characteristics of\r\n', u'hepatitis B virus in chronic hepatitis B virus infected patients\r\n', u'with A1899 mutation in precore region\r\n', u'
Truong Xuan Bui ; Ho Thi Thu Pham ; Phuong Minh Tran ; Son Truong Nguyen ; Long Cong Nguyen ; Trach Khanh Nguyen ; Yasushi Seo ; Yoshihiko Yano
Journal of Medical Research 2007;47(2):64-68
Background: Hepatitis B is an infectious illness caused by hepatitis B virus (HBV) which infects the liver of hominoidea, including humans, and causes an inflammation called hepatitis. Objectives: The aim of study is to clarify clinical features and molecular characteristics of HBV in chronic HBV-infected patients with A 1899 mutation. Subjects and method: HBV genotype, HBV-ONA level, HBeAg and anti-HBe in 29 chronic HBV-infected patients were determined by PCR-RFLP, Real-time PCR and ELISA, respectively. Mutations were analyzed by direct sequencing. Results: Mutations in core-promoter/precore regions of HBV genome can suppress HBeAg secretion and stimulate HBV-ONA replication. The prevalence of hepatocel- lular carcinoma (HCc): 10/29, liver cirrhosis (LC) : 15/29 are significantly higher than that in chronic hepatitis (CH) : 4/29 (P < 0.001). HbeAg seroconversion rate in CH (75%) is higher than that in HCC \r\n', u'(40%) and in LC (53.3%), but not significant (P > 0.05). ALT level is the highest in CH and the lowest in HCC \r\n', u'(P = 0.02), 8/10 (80%) HCC patients have normal range of ALT. HBV-ONA level in HCC and in LC is significantly higher than that in CH (P = 0.024). The emerging of A 1899 is often accompanied by C/G1753 mutation (37.9%) and dual core-promoter mutation T1762A1764 (79.3%). Conclusion: A1899 mutation can play a role in the pathogenesis of liver diseases in chronic HBV-infected Vietnamese.\r\n', u'
Hepatitis B virus/ growth &
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development
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physiology
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Hepatitis B
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Chronic/ pathology
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transmission
4.Polymicrobial Anaerobic Bacteremia Caused by Butyricimonas virosa and Brachyspira pilosicoli in a Patient with Peritonitis following Intestinal Perforation
Yoshihiko OGAWA ; Masatoshi SATO ; Takaya YAMASHITA ; Ryuichi NAKANO ; Satoshi MOCHIZUKI ; Kei KASAHARA ; Hisakazu YANO ; Keiichi MIKASA
Annals of Laboratory Medicine 2018;38(1):71-73
No abstract available.
Bacteremia
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Brachyspira
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Humans
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Intestinal Perforation
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Peritonitis
5. Prevalence and genotype distribution of hepatitis B virus among migrant workers in Lombok Island, Indonesia
Laura YAMANI ; Eva TRIANI ; Mochamad AMIN ; Mochamad JUNIASTUTI ; Mochamad SOETJIPTO ; Mochamad NASRONUDIN ; Hak HOTTA ; Yoshitake HAYASHI ; Maria LUSIDA ; Laura YAMANI ; Laura YAMANI ; Mochamad AMIN ; Mochamad JUNIASTUTI ; Takako UTSUMI ; Takako SOETJIPTO ; Takako NASRONUDIN ; Maria LUSIDA ; Eva TRIANI ; Maria LUSIDA ; Takako UTSUMI ; Yoshihiko YANO
Asian Pacific Journal of Tropical Medicine 2020;13(1):8-16
To examine the potential risk of hepatitis B virus (HBV) spread in Indonesia by migrant workers, based on the molecular characteristics of HBV strains. Methods: Sera collected from migrant workers traveling to their destination countries (pre-migrant workers) and those returning to Indonesia (post-migrant workers) were screened for HBsAg by ELISA, followed by HBV DNA detection by PCR and (sub) genotype/subtype determination according to surface region and whole genome sequencing. Results: Of 87 pre-migrant workers, 15 (17.24%) were HBsAgpositive, whereas 15 (12.10%) of 124 post-migrant workers were HBsAg seropositive. HBV genotype analysis based on the S region showed that HBV-B3/adw2 was predominant (96.15%, 25/26) whereas 3.85% (1/26) of isolates were HBV-C3/adrq+. Whole genome sequencing of selected strains and phylogenetic tree analysis identified subgenotype B7 in three samples previously categorized as subgenotype B3 based on S region analysis, supporting a recent argument that subgenotypes B5/B7/B8/B9 could be considered as a quasi-subgenotype of B3. Conclusions: A high prevalence of HBsAg carriers was detected among migrant workers from Lombok Island, with no significant difference in prevalence between before and after returning to Indonesia. All strains were classified into genotypes common in Indonesia, and the results suggested that migrant workers are not a risk factor for HBV transmission into Indonesia.